Research Output

2020

High-throughput identification of protein functional similarities using a gene-expression-based siRNA screen

Neilsen, B. K., Kelly, D. L., Chakraborty, B., Kim, H. S., White, M. A., Lewis, R. E. & Fisher, K. W., Dec 1 2020, In : Scientific Data. 7, 1, 27.

Research output: Contribution to journalArticle

Open Access

HLA-B influences integrin beta-1 expression and pancreatic cancer cell migration

Sliker, B. H., Goetz, B. T., Barnes, R., King, H., Maurer, H. C., Olive, K. P. & Solheim, J. C., May 15 2020, In : Experimental Cell Research. 390, 2, 111960.

Research output: Contribution to journalArticle

How does fascin promote cancer metastasis?

Lin, S., Taylor, M. D., Singh, P. K. & Yang, S., 2020, (Accepted/In press) In : FEBS Journal.

Research output: Contribution to journalReview article

Open Access

Identification and phylogenetic characterization of bovine ephemeral fever virus (BEFV) of Middle Eastern lineage associated with 2018–2019 outbreaks in India

Pyasi, S., Sahu, B. P., Sahoo, P., Dubey, P. K., Sahoo, N., Byrareddy, S. N. & Nayak, D., 2020, (Accepted/In press) In : Transboundary and Emerging Diseases.

Research output: Contribution to journalArticle

Identification of Fusion Transcripts from Unaligned RNA-Seq Reads Using ChimeRScope

Vellichirammal, N. N., Albahrani, A., Li, Y. & Guda, C., 2020, Methods in Molecular Biology. Humana Press Inc., p. 13-25 13 p. (Methods in Molecular Biology; vol. 2079).

Research output: Chapter in Book/Report/Conference proceedingChapter

IL-17–CXC Chemokine Receptor 2 Axis Facilitates Breast Cancer Progression by Up-Regulating Neutrophil Recruitment

Wu, L., Awaji, M., Saxena, S., Varney, M. L., Sharma, B. & Singh, R. K., Jan 2020, In : American Journal of Pathology. 190, 1, p. 222-233 12 p.

Research output: Contribution to journalArticle

4 Scopus citations

IL-33/IL1RL1 axis regulates cell survival through the p38 MAPK pathway in acute myeloid leukemia

Wang, Y., Luo, H., Wei, M., Becker, M., Hyde, R. K. & Gong, Q., Sep 2020, In : Leukemia Research. 96, 106409.

Research output: Contribution to journalArticle

Image-guided tumor surgery: The emerging role of nanotechnology

Wojtynek, N. E. & Mohs, A. M., Jul 1 2020, In : Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology. 12, 4, e1624.

Research output: Contribution to journalReview article

3 Scopus citations

Immuno-epidemiology and pathophysiology of coronavirus disease 2019 (COVID-19)

Olwenyi, O. A., Dyavar, S. R., Acharya, A., Podany, A. T., Fletcher, C. V., Ng, C. L., Reid, S. P. & Byrareddy, S. N., 2020, (Accepted/In press) In : Journal of Molecular Medicine.

Research output: Contribution to journalReview article

Open Access

Impact of Social Determinants of Health on the Emerging COVID-19 Pandemic in the United States

Singu, S., Acharya, A., Challagundla, K. & Byrareddy, S. N., Jul 21 2020, In : Frontiers in Public Health. 8, 406.

Research output: Contribution to journalReview article

Open Access
1 Scopus citations

In-depth Mendelian randomization analysis of causal factors for coronary artery disease

Tan, Y. D., Xiao, P. & Guda, C., Dec 1 2020, In : Scientific reports. 10, 1, 9208.

Research output: Contribution to journalArticle

Open Access

Inhibitory activity of salivary glycoproteins on phytohemagglutins (PHA): Possible molecules to enhance nutritional quality of red kidney beans

Chachadi, V. B., Nayanegali, T. R., Pujari, B. G., Umarji, L. V., Budyhalamath, V., Inamdar, S. R. & Cheng, P. W., Jun 2020, In : Legume Research. 43, 3, p. 337-344 8 p., LR-4034.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Irreversible and sustained upregulation of endothelin axis during oncogene-associated pancreatic inflammation and cancer

Gupta, S., Prajapati, A., Gulati, M., Gautam, S. K., Kumar, S., Dalal, V., Talmon, G. A., Rachagani, S. & Jain, M., Feb 2020, In : Neoplasia (United States). 22, 2, p. 98-110 13 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

JNK signaling contributes to skeletal muscle wasting and protein turnover in pancreatic cancer cachexia

Mulder, S. E., Dasgupta, A., King, R. J., Abrego, J., Attri, K. S., Murthy, D., Shukla, S. K. & Singh, P. K., Oct 28 2020, In : Cancer Letters. 491, p. 70-77 8 p.

Research output: Contribution to journalArticle

KVA-D-88, a Novel Preferable Phosphodiesterase 4B Inhibitor, Decreases Cocaine-Mediated Reward Properties in Vivo

Burkovetskaya, M. E., Liu, Q., Vadukoot, A. K., Gautam, N., Alnouti, Y., Kumar, S., Miczek, K., Buch, S., Hopkins, C. R. & Guo, M., Aug 5 2020, In : ACS Chemical Neuroscience. 11, 15, p. 2231-2242 12 p.

Research output: Contribution to journalArticle

Lactate production by Staphylococcus aureus biofilm inhibits HDAC11 to reprogramme the host immune response during persistent infection

Heim, C. E., Bosch, M. E., Yamada, K. J., Aldrich, A. L., Chaudhari, S. S., Klinkebiel, D., Gries, C. M., Alqarzaee, A. A., Li, Y., Thomas, V. C., Seto, E., Karpf, A. R. & Kielian, T., 2020, (Accepted/In press) In : Nature Microbiology.

Research output: Contribution to journalArticle

3 Scopus citations

Linking NRP2 With EMT and Chemoradioresistance in Bladder Cancer

Schulz, A., Gorodetska, I., Behrendt, R., Fuessel, S., Erdmann, K., Foerster, S., Datta, K., Mayr, T., Dubrovska, A. & Muders, M. H., Jan 21 2020, In : Frontiers in Oncology. 9, 1461.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Local and systemic immunosuppression in pancreatic cancer: Targeting the stalwarts in tumor's arsenal

Mundry, C. S., Eberle, K. C., Singh, P. K., Hollingsworth, M. A. & Mehla, K., Aug 2020, In : Biochimica et Biophysica Acta - Reviews on Cancer. 1874, 1, 188387.

Research output: Contribution to journalReview article

Open Access

Long non-coding RNAs and nuclear factor-κB crosstalk in cancer and other human diseases

Gupta, S. C., Awasthee, N., Rai, V., Chava, S., Gunda, V. & Challagundla, K. B., Jan 2020, In : Biochimica et Biophysica Acta - Reviews on Cancer. 1873, 1, 188316.

Research output: Contribution to journalReview article

9 Scopus citations
Open Access
1 Scopus citations

Macrophages potentiate STAT3 signaling in skeletal muscles and regulate pancreatic cancer cachexia

Shukla, S. K., Markov, S. D., Attri, K. S., Vernucci, E., King, R. J., Dasgupta, A., Grandgenett, P. M., Hollingsworth, M. A., Singh, P. K., Yu, F. & Mehla, K., Aug 1 2020, In : Cancer Letters. 484, p. 29-39 11 p.

Research output: Contribution to journalArticle

1 Scopus citations

Manganese porphyrin, MnTE-2-PyP, treatment protects the prostate from radiation-induced fibrosis (RIF) by activating the NRF2 signaling pathway and enhancing SOD2 and sirtuin activity

Shrishrimal, S., Chatterjee, A., Kosmacek, E. A., Davis, P. J., McDonald, J. T. & Oberley-Deegan, R. E., May 20 2020, In : Free Radical Biology and Medicine. 152, p. 255-270 16 p.

Research output: Contribution to journalArticle

1 Scopus citations

MASTL: A novel therapeutic target for Cancer Malignancy

Fatima, I., Singh, A. B. & Dhawan, P., Sep 1 2020, In : Cancer Medicine. 9, 17, p. 6322-6329 8 p.

Research output: Contribution to journalReview article

Open Access

Maturation of Lipophagic Organelles in Hepatocytes Is Dependent Upon a Rab10/Dynamin-2 Complex

Li, Z., Weller, S. G., Drizyte-Miller, K., Chen, J., Krueger, E. W., Mehall, B., Casey, C. A., Cao, H. & McNiven, M. A., Aug 1 2020, In : Hepatology. 72, 2, p. 486-502 17 p.

Research output: Contribution to journalArticle

1 Scopus citations

Mechanisms, biomarkers and targets for therapy in alcohol-associated liver injury: From Genetics to nutrition: Summary of the ISBRA 2018 symposium

Kirpich, I. A., Warner, D. R., Feng, W., Joshi-Barve, S., McClain, C. J., Seth, D., Zhong, W., Zhou, Z., Osna, N. A. & Kharbanda, K. K., Mar 2020, In : Alcohol. 83, p. 105-114 10 p.

Research output: Contribution to journalReview article

1 Scopus citations

Mechanistic and functional shades of mucins and associated glycans in colon cancer

Pothuraju, R., Krishn, S. R., Gautam, S. K., Pai, P., Ganguly, K., Chaudhary, S., Rachagani, S., Kaur, S. & Batra, S. K., Mar 2020, In : Cancers. 12, 3, 649.

Research output: Contribution to journalReview article

Open Access
1 Scopus citations

Metabolic alterations in pancreatic cancer progression

Vernucci, E., Abrego, J., Gunda, V., Shukla, S. K., Dasgupta, A., Rai, V., Chaika, N., Buettner, K., Illies, A., Yu, F., Lazenby, A. J., Swanson, B. J. & Singh, P. K., Jan 2020, In : Cancers. 12, 1, 2.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Metabolic subtyping for novel personalized therapies against pancreatic cancer

Mehla, K. & Singh, P. K., Jan 1 2020, In : Clinical Cancer Research. 26, 1, p. 6-8 3 p.

Research output: Contribution to journalArticle

2 Scopus citations

MicroRNAs Orchestrate Pathophysiology of Breast Cancer Brain Metastasis: Advances in Therapy

Kanchan, R. K., Siddiqui, J. A., Mahapatra, S., Batra, S. K. & Nasser, M. W., Feb 15 2020, In : Molecular cancer. 19, 1, 29.

Research output: Contribution to journalReview article

Open Access
2 Scopus citations

MiR-1253 exerts tumor-suppressive effects in medulloblastoma via inhibition of CDK6 and CD276 (B7-H3)

Kanchan, R. K., Perumal, N., Atri, P., Chirravuri Venkata, R., Thapa, I., Klinkebiel, D. L., Donson, A. M., Perry, D., Punsoni, M., Talmon, G. A., Coulter, D. W., Boue’, D. R., Snuderl, M., Nasser, M. W., Batra, S. K., Vibhakar, R. & Mahapatra, S., Jul 1 2020, In : Brain Pathology. 30, 4, p. 732-745 14 p.

Research output: Contribution to journalArticle

1 Scopus citations

miR-15a-5p, miR-15b-5p, and miR-16-5p inhibit tumor progression by directly targeting MYCN in neuroblastoma

Chava, S., Reynolds, C. P., Pathania, A. S., Gorantla, S., Poluektova, L. Y., Coulter, D. W., Gupta, S. C., Pandey, M. K. & Challagundla, K. B., Jan 1 2020, In : Molecular Oncology. 14, 1, p. 180-196 17 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

MnTE-2-PyP, a manganese porphyrin, reduces cytotoxicity caused by irradiation in a diabetic environment through the induction of endogenous antioxidant defenses

Chatterjee, A., Kosmacek, E. A., Shrishrimal, S., McDonald, J. T. & Oberley-Deegan, R. E., Jul 2020, In : Redox Biology. 34, 101542.

Research output: Contribution to journalArticle

Open Access

Mnte-2-pyp suppresses prostate cancer cell growth via h2 o2 production

Zhu, Y., Kosmacek, E. A., Chatterjee, A. & Oberley-Deegan, R. E., Jun 2020, In : Antioxidants. 9, 6, 490.

Research output: Contribution to journalArticle

Open Access

MnTnBuOE-2-PyP treatment protects from radioactive iodine (I-131) treatment-related side effects in thyroid cancer

Patel, A., Kosmacek, E. A., Fisher, K. W., Goldner, W. & Oberley-Deegan, R. E., Mar 1 2020, In : Radiation and Environmental Biophysics. 59, 1, p. 99-109 11 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Modeling human-specific interlaminar astrocytes in the mouse cerebral cortex

Padmashri, R., Ren, B., Oldham, B., Jung, Y., Gough, R. & Dunaevsky, A., 2020, (Accepted/In press) In : Journal of Comparative Neurology.

Research output: Contribution to journalArticle

Open Access

Modified Papanicolaou staining for oral swab samples stored long term

Uppada, S. B., Madduri, L. S. V., Singu, S., Lawson, B., Bauer, L., Freifeld, A., Bhatt, V. R. & Byrareddy, S. N., 2020, (Accepted/In press) In : Biotechnic and Histochemistry.

Research output: Contribution to journalArticle

Molecular aspects of COVID-19 differential pathogenesis

Rothan, H. A., Acharya, A., Reid, S. P., Kumar, M. & Byrareddy, S. N., Jul 2020, In : Pathogens. 9, 7, p. 1-9 9 p., 538.

Research output: Contribution to journalReview article

Open Access
1 Scopus citations

Molecular implications of MUC5AC-CD44 axis in colorectal cancer progression and chemoresistance

Pothuraju, R., Rachagani, S., Krishn, S. R., Chaudhary, S., Nimmakayala, R. K., Siddiqui, J. A., Ganguly, K., Lakshmanan, I., Cox, J. L., Mallya, K., Kaur, S. & Batra, S. K., Feb 25 2020, In : Molecular cancer. 19, 1, 37.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Molecular targeting of renal cell carcinoma by an oral combination

Jordan, A. R., Wang, J., Yates, T. J., Hasanali, S. L., Lokeshwar, S. D., Morera, D. S., Shamaladevi, N., Li, C. S., Klaassen, Z., Terris, M. K., Thangaraju, M., Singh, A. B., Soloway, M. S. & Lokeshwar, V. B., May 1 2020, In : Oncogenesis. 9, 5, 52.

Research output: Contribution to journalArticle

Open Access

Monocyte metabolic reprogramming promotes pro-inflammatory activity and Staphylococcus aureus biofilm clearance

Yamada, K. J., Heim, C. E., Xi, X., Attri, K. S., Wang, D., Zhang, W., Singh, P. K., Bronich, T. K. & Kielian, T., 2020, In : PLoS pathogens. 16, 3, e1008354.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

MUC16 as a potential target for the surgical detection of pancreatic cancer

Olson, M. T., Wojtynek, N. E., Caffrey, T. C., Radhakrishnan, P., Ly, Q. P., Talmon, G. A., Hollingsworth, M. A. & Mohs, A. M., 2020, Molecular-Guided Surgery: Molecules, Devices, and Applications VI. Gioux, S., Gibbs, S. L. & Pogue, B. W. (eds.). SPIE, 112220M. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 11222).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

MUC1 oncoprotein mitigates ER stress via CDA-mediated reprogramming of pyrimidine metabolism

Olou, A. A., King, R. J., Yu, F. & Singh, P. K., Apr 16 2020, In : Oncogene. 39, 16, p. 3381-3395 15 p.

Research output: Contribution to journalArticle

1 Scopus citations

MUCIN-4 (MUC4) is a novel tumor antigen in pancreatic cancer immunotherapy

Gautam, S. K., Kumar, S., Dam, V., Ghersi, D., Jain, M. & Batra, S. K., Feb 2020, In : Seminars in Immunology. 47, 101391.

Research output: Contribution to journalReview article

1 Scopus citations

MyD88 regulates a prolonged adaptation response to environmental dust exposure-induced lung disease

Johnson, A. N., Harkema, J. R., Nelson, A. J., Dickinson, J. D., Kalil, J., Duryee, M. J., Thiele, G. M., Kumar, B., Singh, A. B., Gaurav, R., Glover, S. C., Tang, Y., Romberger, D. J., Kielian, T. & Poole, J. A., Apr 22 2020, In : Respiratory Research. 21, 1, 97.

Research output: Contribution to journalArticle

Open Access

Nanoformulation of CCL21 greatly increases its effectiveness as an immunotherapy for neuroblastoma

Poelaert, B. J., Romanova, S., Knoche, S. M., Olson, M. T., Sliker, B. H., Smits, K., Dickey, B. L., Moffitt-Holida, A. E. J., Goetz, B. T., Khan, N., Smith, L., Band, H., Mohs, A. M., Coulter, D. W., Bronich, T. K. & Solheim, J. C., Nov 10 2020, In : Journal of Controlled Release. 327, p. 266-283 18 p.

Research output: Contribution to journalArticle

Nanoformulation of the superoxide dismutase mimic, MnTnBuOE-2-PyP5+, prevents its acute hypotensive response

Schlichte, S. L., Romanova, S., Katsurada, K., Kosmacek, E. A., Bronich, T. K., Patel, K. P., Oberley-Deegan, R. E. & Zimmerman, M. C., Sep 2020, In : Redox Biology. 36, 101610.

Research output: Contribution to journalArticle

Open Access

Nanoparticle Formulation of Indocyanine Green Improves Image-Guided Surgery in a Murine Model of Breast Cancer

Wojtynek, N. E., Olson, M. T., Bielecki, T. A., An, W., Bhat, A. M., Band, H., Lauer, S. R., Silva-Lopez, E. & Mohs, A. M., Aug 1 2020, In : Molecular Imaging and Biology. 22, 4, p. 891-903 13 p.

Research output: Contribution to journalArticle

1 Scopus citations