Research Output

2020

Neuropilin-2 is an independent prognostic factor for shorter cancer-specific survival in patients with acinar adenocarcinoma of the prostate

Borkowetz, A., Froehner, M., Rauner, M., Conrad, S., Erdmann, K., Mayr, T., Datta, K., Hofbauer, L. C., Baretton, G. B., Wirth, M., Fuessel, S., Toma, M. & Muders, M. H., May 1 2020, In : International Journal of Cancer. 146, 9, p. 2619-2627 9 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Neutrophils are mediators of metastatic prostate cancer progression in bone

Costanzo-Garvey, D. L., Keeley, T., Case, A. J., Watson, G. F., Alsamraae, M., Yu, Y., Su, K., Heim, C. E., Kielian, T., Morrissey, C., Frieling, J. S. & Cook, L. M., Jun 1 2020, In : Cancer Immunology, Immunotherapy. 69, 6, p. 1113-1130 18 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Neutrophils in the Tumor Microenvironment

Wu, L., Saxena, S. & Singh, R. K., 2020, Advances in Experimental Medicine and Biology. Springer, p. 1-20 20 p. (Advances in Experimental Medicine and Biology; vol. 1224).

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations

NF-κB Duplications in the Promoter-Variant HIV-1C LTR Impact Inflammation Without Altering Viral Replication in the Context of Simian Human Immunodeficiency Viruses and Opioid-Exposure

Dave, R. S., Ali, H., Sil, S., Knight, L. A., Pandey, K., Madduri, L. S. V., Qiu, F., Ranga, U., Buch, S. & Byrareddy, S. N., Jan 31 2020, In : Frontiers in immunology. 11, 95.

Research output: Contribution to journalArticle

Open Access

Odyssey of trefoil factors in cancer: Diagnostic and therapeutic implications

Jahan, R., Shah, A., Kisling, S. G., Macha, M. A., Thayer, S., Batra, S. K. & Kaur, S., Apr 2020, In : Biochimica et Biophysica Acta - Reviews on Cancer. 1873, 2, 188362.

Research output: Contribution to journalReview article

Old drugs, new uses: Drug repurposing in hematological malignancies

Kale, V. P., Habib, H., Chitren, R., Patel, M., Pramanik, K. C., Jonnalagadda, S. C., Challagundla, K. & Pandey, M. K., 2020, (Accepted/In press) In : Seminars in Cancer Biology.

Research output: Contribution to journalReview article

1 Scopus citations

Opportunities, risks and challenges in global mental health and population neuroscience: a case of Sino-German cooperation

Liu, S., Müller, S., Dolan, R. J., Zhao, X., Zheng, J. C. & Heinz, A., 2020, (Accepted/In press) In : European Archives of Psychiatry and Clinical Neuroscience.

Research output: Contribution to journalReview article

Open Access

Pan-cancer analysis of whole genomes

The ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium, Feb 6 2020, In : Nature. 578, 7793, p. 82-93 12 p.

Research output: Contribution to journalArticle

Open Access
109 Scopus citations

Pan-Cancer Analysis Reveals the Diverse Landscape of Novel Sense and Antisense Fusion Transcripts

Vellichirammal, N. N., Albahrani, A., Banwait, J. K., Mishra, N. K., Li, Y., Roychoudhury, S., Kling, M. J., Mirza, S., Bhakat, K. K., Band, V., Joshi, S. S. & Guda, C., Mar 6 2020, In : Molecular Therapy - Nucleic Acids. 19, p. 1379-1398 20 p.

Research output: Contribution to journalArticle

Open Access

Pancreatic ductal adenocarcinoma progression is restrained by stromal matrix

Jiang, H., Torphy, R. J., Steiger, K., Hongo, H., Ritchie, A. J., Kriegsmann, M., Horst, D., Umetsu, S. E., Joseph, N. M., McGregor, K., Pishvaian, M. J., Edik, M. B., Lu, B., Li, M., Hollingsworth, M., Stashko, C., Volmar, K., Yeh, J. J., Weaver, V. M., Wang, Z. J. & 3 others, Tempero, M. A., Weichert, W. & Collisson, E. A., Sep 1 2020, In : Journal of Clinical Investigation. 130, 9, p. 4704-4709 6 p.

Research output: Contribution to journalArticle

Open Access

Pancreatic Stellate Cells: The Key Orchestrator of The Pancreatic Tumor Microenvironment

Thomas, D. & Radhakrishnan, P., 2020, Advances in Experimental Medicine and Biology. Springer, p. 57-70 14 p. (Advances in Experimental Medicine and Biology; vol. 1234).

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations

Placental DNA methylation changes in detection of tetralogy of Fallot

Bahado-Singh, R., Vishweswaraiah, S., Mishra, N. K., Guda, C. & Radhakrishna, U., Jun 1 2020, In : Ultrasound in Obstetrics and Gynecology. 55, 6, p. 768-775 8 p.

Research output: Contribution to journalArticle

Polyanhydride nanoparticles stabilize pancreatic cancer antigen MUC4β

Liu, L., Kshirsagar, P., Christiansen, J., Gautam, S. K., Aithal, A., Gulati, M., Kumar, S., Solheim, J. C., Batra, S. K., Jain, M., Wannemuehler, M. J. & Narasimhan, B., 2020, (Accepted/In press) In : Journal of Biomedical Materials Research - Part A.

Research output: Contribution to journalArticle

Precision cardiovascular medicine: artificial intelligence and epigenetics for the pathogenesis and prediction of coarctation in neonates

Bahado-Singh, R. O., Vishweswaraiah, S., Aydas, B., Yilmaz, A., Saiyed, N. M., Mishra, N. K., Guda, C. & Radhakrishna, U., 2020, (Accepted/In press) In : Journal of Maternal-Fetal and Neonatal Medicine.

Research output: Contribution to journalArticle

2 Scopus citations

Precision medicine and actionable alterations in lung cancer: A single institution experience

Mambetsariev, I., Wang, Y., Chen, C., Nadaf, S., Pharaon, R., Fricke, J., Amanam, I., Amini, A., Bild, A., Chu, P., Erhunmwunsee, L., Kim, J., Munu, J., Pillai, R., Raz, D., Sampath, S., Vora, L., Qiu, F., Smith, L., Batra, S. K. & 4 others, Massarelli, E., Koczywas, M., Reckamp, K. & Salgia, R., Feb 1 2020, In : PloS one. 15, 2, e0228188.

Research output: Contribution to journalArticle

Open Access

Predicted Prognosis of Patients with Pancreatic Cancer by Machine Learning

Yokoyama, S., Hamada, T., Higashi, M., Matsuo, K., Maemura, K., Kurahara, H., Horinouchi, M., Hiraki, T., Sugimoto, T., Akahane, T., Yonezawa, S., Kornmann, M., Batra, S. K., Hollingsworth, M. A. & Tanimoto, A., May 15 2020, In : Clinical Cancer Research. 26, 10, p. 2411-2421 11 p.

Research output: Contribution to journalArticle

Presence and structure-activity relationship of intrinsically disordered regions across mucins

Carmicheal, J., Atri, P., Sharma, S., Kumar, S., Chirravuri Venkata, R., Kulkarni, P., Salgia, R., Ghersi, D., Kaur, S. & Batra, S. K., Feb 1 2020, In : FASEB Journal. 34, 2, p. 1939-1957 19 p.

Research output: Contribution to journalArticle

Open Access

Prognostic and therapeutic implications of NHERF1 expression and regulation in colorectal cancer

Leiphrakpam, P. D., Lazenby, A. J., Chowdhury, S., Smith, L. M., Mathiesen, M., Brattain, M. G., Wang, J., Black, J. D. & Are, C., Mar 1 2020, In : Journal of Surgical Oncology. 121, 3, p. 547-560 14 p.

Research output: Contribution to journalArticle

Prognostic relevance and inter-observer reliability of chest-imaging in pediatric ARDS: a pediatric acute respiratory distress incidence and epidemiology (PARDIE) study

the Pediatric Acute Respiratory Distress Syndrome Incidence and Epidemiology (PARDIE) V3 Investigators and the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network, Jul 1 2020, In : Intensive Care Medicine. 46, 7, p. 1382-1393 12 p.

Research output: Contribution to journalArticle

Open Access

Proximal tubule cyclophilin D regulates fatty acid oxidation in cisplatin-induced acute kidney injury

Jang, H. S., Noh, M. R., Jung, E. M., Kim, W. Y., Southekal, S., Guda, C., Foster, K. W., Oupicky, D., Ferrer, F. A. & Padanilam, B. J., Feb 2020, In : Kidney International. 97, 2, p. 327-339 13 p.

Research output: Contribution to journalArticle

2 Scopus citations

Radiomics-based outcome prediction for pancreatic cancer following stereotactic body radiotherapy

Parr, E., Du, Q., Zhang, C., Lin, C., Kamal, A., McAlister, J., Liang, X., Bavitz, K., Rux, G., Hollingsworth, M., Baine, M. & Zheng, D., Apr 2020, In : Cancers. 12, 4, 1051.

Research output: Contribution to journalArticle

Open Access

Radiomics in stratification of pancreatic cystic lesions: Machine learning in action

Dalal, V., Carmicheal, J., Dhaliwal, A., Jain, M., Kaur, S. & Batra, S. K., Jan 28 2020, In : Cancer Letters. 469, p. 228-237 10 p.

Research output: Contribution to journalReview article

2 Scopus citations

Recent Advances in the Development of Integrase Inhibitors for HIV Treatment

Trivedi, J., Mahajan, D., Jaffe, R. J., Acharya, A., Mitra, D. & Byrareddy, S. N., Feb 1 2020, In : Current HIV/AIDS Reports. 17, 1, p. 63-75 13 p.

Research output: Contribution to journalReview article

Recent advances in understanding the complexity of alcohol-induced pancreatic dysfunction and pancreatitis development

Rasineni, K., Srinivasan, M. P., Balamurugan, A. N., Kaphalia, B. S., Wang, S., Ding, W. X., Pandol, S. J., Lugea, A., Simon, L., Molina, P. E., Gao, P., Casey, C. A., Osna, N. A. & Kharbanda, K. K., May 2020, In : Biomolecules. 10, 5, 669.

Research output: Contribution to journalReview article

Open Access
1 Scopus citations

Reprogrammed astrocytes display higher neurogenic competence, migration ability and cell death resistance than reprogrammed fibroblasts

Xia, X., Li, C., Wang, Y., Deng, X., Ma, Y., Ding, L. & Zheng, J., Feb 8 2020, In : Translational Neurodegeneration. 9, 1, 6.

Research output: Contribution to journalArticle

Open Access

Reprogramming of ovarian granulosa cells by YAP1 leads to development of high-grade cancer with mesenchymal lineage and serous features

Lv, X., He, C., Huang, C., Hua, G., Chen, X., Timm, B. K., Maclin, V. M., Haggerty, A. A., Aust, S. K., Golden, D. M., Dave, B. J., Tseng, Y. A., Chen, L., Wang, H., Chen, P., Klinkebiel, D. L., Karpf, A. R., Dong, J., Drapkin, R. I., Rueda, B. R. & 2 others, Davis, J. S. & Wang, C., Aug 15 2020, In : Science Bulletin. 65, 15, p. 1281-1296 16 p.

Research output: Contribution to journalArticle

RIG-I and TLR4 responses and adverse outcomes in pediatric influenza-related critical illness

PALISI Pediatric Intensive Care Influenza (PICFLU) Network Investigators, Jun 2020, In : Journal of Allergy and Clinical Immunology. 145, 6, p. 1673-1680.e11

Research output: Contribution to journalArticle

Rilpivirine-associated aggregation-induced emission enables cell-based nanoparticle tracking

Mukadam, I. Z., Machhi, J., Herskovitz, J., Hasan, M., Oleynikov, M. D., Blomberg, W. R., Svechkarev, D., Mohs, A. M., Zhou, Y., Dash, P., McMillan, J. E., Gorantla, S., Garrison, J., Gendelman, H. E. & Kevadiya, B. D., Feb 2020, In : Biomaterials. 231, 119669.

Research output: Contribution to journalArticle

Role of alcohol in pathogenesis of hepatitis B virus infection

Ganesan, M., Eikenberry, A., Poluektova, L. Y., Kharbanda, K. K. & Osna, N. A., Mar 7 2020, In : World Journal of Gastroenterology. 26, 9, p. 883-903 21 p.

Research output: Contribution to journalReview article

Open Access
1 Scopus citations

Role of Brain Derived Extracellular Vesicles in Decoding Sex Differences Associated with Nicotine Self-Administration

Koul, S., Schaal, V. L., Chand, S., Pittenger, S. T., Nanoth Vellichirammal, N., Kumar, V., Guda, C., Bevins, R. A., Yelamanchili, S. V. & Pendyala, G., Aug 11 2020, In : Cells. 9, 8

Research output: Contribution to journalArticle

Open Access
Open Access
2 Scopus citations

Role of Elevated Intracellular S-Adenosylhomocysteine in the Pathogenesis of Alcohol-Related Liver Disease

Arumugam, M. K., Talawar, S., Listenberger, L., Donohue, T. M., Osna, N. A. & Kharbanda, K. K., Jun 23 2020, In : Cells. 9, 6

Research output: Contribution to journalArticle

Open Access

Role of non-Genetic Risk Factors in Exacerbating Alcohol-related organ damage

Osna, N. A., Bhatia, R., Thompson, C., Batra, S. K., Kumar, S., Cho, Y., Szabo, G., Molina, P. E., Weinman, S. A., Ganesan, M. & Kharbanda, K. K., Sep 2020, In : Alcohol. 87, p. 63-72 10 p.

Research output: Contribution to journalReview article

Role of Small Intestine and Gut Microbiome in Plant-Based Oral Tolerance for Hemophilia

Kumar, S. R. P., Wang, X., Avuthu, N., Bertolini, T. B., Terhorst, C., Guda, C., Daniell, H. & Herzog, R. W., May 20 2020, In : Frontiers in immunology. 11, 844.

Research output: Contribution to journalArticle

Open Access

Role of tumor and stroma-derived IGF/IGFBPS in pancreatic cancer

Thomas, D. & Radhakrishnan, P., May 2020, In : Cancers. 12, 5, 1228.

Research output: Contribution to journalReview article

Open Access

Safety and Immunological Evaluation of Interleukin-21 Plus Anti-α4β7 mAb Combination Therapy in Rhesus Macaques

Pino, M., Uppada, S. B., Pandey, K., King, C., Nguyen, K., Shim, I., Rogers, K., Villinger, F., Paiardini, M. & Byrareddy, S. N., Jul 17 2020, In : Frontiers in immunology. 11, 1275.

Research output: Contribution to journalArticle

Open Access

SARS-CoV-2 Infection Leads to Neurological Dysfunction

Acharya, A., Kevadiya, B. D., Gendelman, H. E. & Byrareddy, S. N., Jun 1 2020, In : Journal of Neuroimmune Pharmacology. 15, 2, p. 167-173 7 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations
10 Scopus citations

Short-term stable isotope probing of proteins reveals taxa incorporating inorganic carbon in a hot spring microbial mat

Steinke, L., Slysz, G. W., Lipton, M. S., Klatt, C., Moran, J. J., Romine, M. F., Wood, J. M., Anderson, G., Bryant, D. A. & Ward, D. M., Mar 1 2020, In : Applied and environmental microbiology. 86, 7, 1829.

Research output: Contribution to journalArticle

1 Scopus citations

Sirt1–nox4 signaling axis regulates cancer cachexia

Dasgupta, A., Shukla, S. K., Vernucci, E., King, R. J., Abrego, J., Mulder, S. E., Mullen, N. J., Graves, G., Buettner, K., Thakur, R., Murthy, D., Attri, K. S., Wang, D., Chaika, N. V., Pacheco, C. G., Rai, I., Engle, D. D., Grandgenett, P. M., Punsoni, M., Reames, B. N. & 10 others, Teoh-Fitzgerald, M., Oberley-Deegan, R., Yu, F., Klute, K. A., Hollingsworth, M. A., Zimmerman, M. C., Mehla, K., Sadoshima, J., Tuveson, D. A. & Singh, P. K., Jul 6 2020, In : Journal of Experimental Medicine. 217, 7, e20190745.

Research output: Contribution to journalArticle

1 Scopus citations

Solvent tuning of photochemistry upon excited-state symmetry breaking

Dereka, B., Svechkarev, D., Rosspeintner, A., Aster, A., Lunzer, M., Liska, R., Mohs, A. M. & Vauthey, E., Dec 1 2020, In : Nature communications. 11, 1, 1925.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Sorting nexin 17 (SNX17) links endosomal sorting to Eps15 homology domain protein 1 (EHD1)-mediated fission machinery

Dhawan, K., Naslavsky, N., Caplan, S. & Hanson, P. I., Mar 20 2020, In : Journal of Biological Chemistry. 295, 12, p. 3837-3850 14 p.

Research output: Contribution to journalArticle

1 Scopus citations

Squamous trans-differentiation of pancreatic cancer cells promotes stromal inflammation

Somerville, T. D. D., Biffi, G., Daßler-Plenker, J., Hur, S. K., He, X. Y., Vance, K. E., Miyabayashi, K., Xu, Y., Maia-Silva, D., Klingbeil, O., Demerdash, O. E., Preall, J. B., Hollingsworth, M. A., Egeblad, M., Tuveson, D. A. & Vakoc, C. R., Apr 2020, In : eLife. 9, e53381.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Stromal Modulation and Treatment of Metastatic Pancreatic Cancer with Local Intraperitoneal Triple miRNA/siRNA Nanotherapy

Xie, Y., Hang, Y., Wang, Y., Sleightholm, R., Prajapati, D. R., Bader, J., Yu, A., Tang, W., Jaramillo, L., Li, J., Singh, R. K. & Oupický, D., Jan 28 2020, In : ACS Nano. 14, 1, p. 255-271 17 p.

Research output: Contribution to journalArticle

4 Scopus citations

Sulfation Modulates the Targeting Properties of Hyaluronic Acid to P-Selectin and CD44

Bhattacharya, D. S., Svechkarev, D., Bapat, A., Patil, P., Hollingsworth, M. A. & Mohs, A. M., Jun 8 2020, In : ACS Biomaterials Science and Engineering. 6, 6, p. 3585-3598 14 p.

Research output: Contribution to journalArticle

Targeting pulmonary tumor microenvironment with CXCR4-inhibiting nanocomplex to enhance anti–PD-L1 immunotherapy

Li, Z., Wang, Y., Shen, Y., Qian, C., Oupicky, D. & Sun, M., May 2020, In : Science Advances. 6, 20, eaaz9240.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Targeting the IκB Kinase Enhancer and Its Feedback Circuit in Pancreatic Cancer

Challa, S., Husain, K., Kim, R., Coppola, D., Batra, S. K., Cheng, J. Q. & Malafa, M. P., Feb 2020, In : Translational Oncology. 13, 2, p. 481-489 9 p.

Research output: Contribution to journalArticle

Open Access

Targeting the Tumor Core: Hypoxia-Responsive Nanoparticles for the Delivery of Chemotherapy to Pancreatic Tumors

Confeld, M. I., Mamnoon, B., Feng, L., Jensen-Smith, H., Ray, P., Froberg, J., Kim, J., Hollingsworth, M. A., Quadir, M., Choi, Y. & Mallik, S., Aug 3 2020, In : Molecular Pharmaceutics. 17, 8, p. 2849-2863 15 p.

Research output: Contribution to journalArticle

The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak

Rothan, H. A. & Byrareddy, S. N., May 2020, In : Journal of Autoimmunity. 109, 102433.

Research output: Contribution to journalReview article

Open Access
555 Scopus citations