Research Output

2019

Direct and selective lineage conversion of human fibroblasts to dopaminergic precursors

He, M., Zhang, H., Li, Y., Tian, C., Tang, B., Huang, Y. & Zheng, J., Apr 23 2019, In : Neuroscience Letters. 699, p. 16-23 8 p.

Research output: Contribution to journalArticle

Discovery, synthesis and characterization of a series of (1-alkyl-3-methyl-1H-pyrazol-5-yl)-2-(5-aryl-2H-tetrazol-2-yl)acetamides as novel GIRK1/2 potassium channel activators

Sharma, S., Kozek, K. A., Abney, K. K., Kumar, S., Gautam, N., Alnouti, Y., David Weaver, C. & Hopkins, C. R., Mar 15 2019, In : Bioorganic and Medicinal Chemistry Letters. 29, 6, p. 791-796 6 p.

Research output: Contribution to journalArticle

Divergent HIV-1-directed immune responses generated by systemic and mucosal immunization with replicating single-cycle adenoviruses in rhesus macaques

Matchett, W. E., Anguiano-Zarate, S. S., Nehete, P. N., Shelton, K., Nehete, B. P., Yang, G., Dorta-Estremera, S., Barnette, P., Xiao, P., Byrareddy, S. N., Villinger, F., Hessell, A. J., Haigwood, N. L., Sastry, K. J. & Barry, M. A., May 1 2019, In : Journal of virology. 93, 10, e02016-18.

Research output: Contribution to journalArticle

5 Scopus citations

Downregulation of an evolutionary young mir-1290 in an ipscderived neural stem cell model of autism spectrum disorder

Moore, D., Meays, B. M., Madduri, L. S. V., Shahjin, F., Chand, S., Niu, M., Albahrani, A., Guda, C., Pendyala, G., Fox, H. S. & Yelamanchili, S. V., 2019, In : Stem Cells International. 2019, 8710180.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Dual delivery nanoscale device for miR-345 and gemcitabine co-delivery to treat pancreatic cancer

Uz, M., Kalaga, M., Pothuraju, R., Ju, J., Junker, W. M., Batra, S. K., Mallapragada, S. & Rachagani, S., Jan 28 2019, In : Journal of Controlled Release. 294, p. 237-246 10 p.

Research output: Contribution to journalArticle

6 Scopus citations

Effect of nanoformulated copper/zinc superoxide dismutase on chronic ethanol-induced alterations in liver and adipose tissue

Natarajan, G., Perriotte-Olson, C., Casey, C. A., Donohue, T. M., Talmon, G. A., Harris, E. N., Kabanov, A. V. & Saraswathi, V., Sep 2019, In : Alcohol. 79, p. 71-79 9 p.

Research output: Contribution to journalArticle

2 Scopus citations

Efficacy of indocyanine green-loaded hyaluronic acid nanoparticles for the surgical resection of orthotopic breast tumors

Wojtynek, N. E., Holmes, M. B., Olson, M. T., Baher, F., Silva, E. & Mohs, A. M., 2019, Molecular-Guided Surgery: Molecules, Devices, and Applications V. Pogue, B. W. & Gioux, S. (eds.). SPIE, 108621G. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 10862).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Engineering hydrogel based cancer microenvironments for in vitro breast cancer cell culture and therapeutics screening

Shi, W., Kuss, M. A., Mohapatra, B., Mirza, S., Band, H., Band, V. & Duan, B., 2019, Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting. Society for Biomaterials, p. 642 1 p. (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium; vol. 40).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Enhancing responsiveness of pancreatic cancer cells to gemcitabine treatment under hypoxia by heme oxygenase-1 inhibition

Abdalla, M. Y., Ahmad, I. M., Rachagani, S., Banerjee, K., Thompson, C. M., Maurer, H. C., Olive, K. P., Bailey, K. L., Britigan, B. E. & Kumar, S., May 2019, In : Translational Research. 207, p. 56-69 14 p.

Research output: Contribution to journalArticle

11 Scopus citations

Epigenetic activation of POTE genes in ovarian cancer

Sharma, A., Albahrani, M., Zhang, W., Kufel, C. N., James, S. R., Odunsi, K., Klinkebiel, D. & Karpf, A. R., Feb 1 2019, In : Epigenetics. 14, 2, p. 185-197 13 p.

Research output: Contribution to journalArticle

3 Scopus citations

Epigenetically dysregulated genes and pathways implicated in the pathogenesis of non-syndromic high myopia

Vishweswaraiah, S., Swierkowska, J., Ratnamala, U., Mishra, N. K., Guda, C., Chettiar, S. S., Johar, K. R., Mrugacz, M., Karolak, J. A., Gajecka, M. & Radhakrishna, U., Dec 1 2019, In : Scientific reports. 9, 1, 4145.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

ERK-mediated TIMELESS expression suppresses G2/M arrest in colon cancer cells

Neilsen, B. K., Frodyma, D. E., McCall, J. L., Fisher, K. W. & Lewis, R. E., Jan 2019, In : PloS one. 14, 1, e0209224.

Research output: Contribution to journalArticle

3 Scopus citations

Erratum: O-GlcNAc Transferase Suppresses Inflammation and Necroptosis by Targeting Receptor-Interacting Serine/Threonine-Protein Kinase 3 (Immunity (2019) 50(3) (576–590.e6), (S1074761319300305), (10.1016/j.immuni.2019.01.007))

Li, X., Gong, W., Wang, H., Li, T., Attri, K. S., Lewis, R. E., Kalil, A. C., Bhinderwala, F., Powers, R., Yin, G., Herring, L. E., Asara, J. M., Lei, Y. L., Yang, X., Rodriguez, D. A., Yang, M., Green, D. R., Singh, P. K. & Wen, H., Apr 16 2019, In : Immunity. 50, 4, p. 1115 1 p.

Research output: Contribution to journalComment/debate

Ethanol withdrawal mitigates fatty liver by normalizing lipid catabolism

Thomes, P. G., Rasineni, K., Yang, L., Donohue, T. M., Kubik, J. L., McNiven, M. A. & Casey, C. A., Apr 2019, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 316, 4, p. G509-G518

Research output: Contribution to journalArticle

5 Scopus citations

Evaluating the metabolic alterations in pancreatic cancer

Dasgupta, A., Shukla, S. K., Gunda, V., King, R. J. & Singh, P. K., 2019, Methods in Molecular Biology. Humana Press Inc., p. 221-228 8 p. (Methods in Molecular Biology; vol. 1882).

Research output: Chapter in Book/Report/Conference proceedingChapter

Exosomal miRNAs in central nervous system diseases: biomarkers, pathological mediators, protective factors and therapeutic agents

Xia, X., Wang, Y., Huang, Y., Zhang, H., Lu, H. & Zheng, J. C., Dec 2019, In : Progress in Neurobiology. 183, 101694.

Research output: Contribution to journalReview article

Open Access
5 Scopus citations

Exosomes released from neural progenitor cells and induced neural progenitor cells regulate neurogenesis through miR-21a

Ma, Y., Li, C., Huang, Y., Wang, Y., Xia, X. & Zheng, J. C., Aug 16 2019, In : Cell Communication and Signaling. 17, 1, 96.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Factors Predictive of Reoperation After Pancreaticoduodenectomy for Pancreatic Cancer

Hall, B. R., Sleightholm, R., Smith, L., Sayles, H. & Are, C., Jan 1 2019, In : Indian Journal of Surgical Oncology.

Research output: Contribution to journalArticle

Fascin Controls Metastatic Colonization and Mitochondrial Oxidative Phosphorylation by Remodeling Mitochondrial Actin Filaments

Lin, S., Huang, C., Gunda, V., Sun, J., Chellappan, S. P., Li, Z., Izumi, V., Fang, B., Koomen, J., Singh, P. K., Hao, J. & Yang, S., Sep 10 2019, In : Cell Reports. 28, 11, p. 2824-2836.e8

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

FDPS cooperates with PTEN loss to promote prostate cancer progression through modulation of small GTPases/AKT axis

Seshacharyulu, P., Rachagani, S., Muniyan, S., Siddiqui, J. A., Cruz, E., Sharma, S., Krishnan, R., Killips, B. J., Sheinin, Y., Lele, S. M., Smith, L. M., Talmon, G. A., Ponnusamy, M. P., Datta, K. & Batra, S. K., Jun 27 2019, In : Oncogene. 38, 26, p. 5265-5280 16 p.

Research output: Contribution to journalArticle

5 Scopus citations

Fluorescence Guidance in Surgical Oncology: Challenges, Opportunities, and Translation

Olson, M. T., Ly, Q. P. & Mohs, A. M., Apr 15 2019, In : Molecular Imaging and Biology. 21, 2, p. 200-218 19 p.

Research output: Contribution to journalReview article

10 Scopus citations

Global Forum of Cancer Surgeons: Perspectives on Barriers to Surgical Care for Cancer Patients and Potential Solutions

Are, C., McMasters, K. M., Giuliano, A., Yanala, U., Balch, C., Anderson, B. O., Berman, R., Audisio, R., Kovacs, T., Savant, D., Toprani, R., Amira, G., Sallam, I., Baek, J. H., Baek, M. J., Park, D. J., Beulo, G. Q., Rocha, E. B., Said, H. M., Cheema, M. & 11 others, AliKhan, A., Mack, L., Chen, G., Quadros, C. A., Reis, T., de Castro Ribeiro, H. S., Zippel, D., Ramirez, A. L., Seto, Y., Yoshida, K. & Mori, M., Jan 1 2019, In : Annals of Surgical Oncology.

Research output: Contribution to journalEditorial

Open Access
3 Scopus citations

Glutaminase C regulates microglial activation and pro-inflammatory exosome release: Relevance to the pathogenesis of Alzheimer’s disease

Gao, G., Zhao, S., Xia, X., Li, C., Li, C., Ji, C., Sheng, S., Tang, Y., Zhu, J., Wang, Y., Huang, Y. & Zheng, J. C., May 14 2019, In : Frontiers in Cellular Neuroscience. 13, 264.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Glycosylation of zika virus is important in host–virus interaction and pathogenic potential

Routhu, N. K., Lehoux, S. D., Rouse, E. A., Bidokhti, M. R. M., Giron, L. B., Anzurez, A., Reid, S. P., Abdel-Mohsen, M., Cummings, R. D. & Byrareddy, S. N., Oct 2019, In : International journal of molecular sciences. 20, 20, 5206.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

HDAC1 is a required cofactor of CBFb-SMMHC and a potential therapeutic target in inversion 16 acute myeloid leukemia

Richter, L. E., Wang, Y., Becker, M. E., Coburn, R. A., Williams, J. T., Amador, C. & Hyde, R. K., Jun 1 2019, In : Molecular Cancer Research. 17, 6, p. 1241-1252 12 p.

Research output: Contribution to journalArticle

1 Scopus citations

Hepatic Inactivation of the Type 2 Deiodinase Confers Resistance to Alcoholic Liver Steatosis

Fonseca, T. L., Fernandes, G. W., Bocco, B. M. L. C., Keshavarzian, A., Jakate, S., Donohue, T. M., Gereben, B. & Bianco, A. C., Jul 2019, In : Alcoholism: Clinical and Experimental Research. 43, 7, p. 1376-1383 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Hepatobiliary cancers, version 2.2019 featured updates to the NCCN guidelines

Benson, A. B., D'Angelica, M. I., Abbott, D. E., Abrams, T. A., Alberts, S. R., Anaya, D. A., Anders, R., Are, C., Brown, D., Chang, D. T., Cloyd, J., Covey, A. M., Hawkins, W., Iyer, R., Jacob, R., Karachristos, A., Kate Kelley, R., Kim, R., Palta, M., Park, J. O. & 11 others, Sahai, V., Schefter, T., Sicklick, J. K., Singh, G., Sohal, D., Stein, S., Gary Tian, G., Vauthey, J. N., Venook, A. P., Hammond, L. J. & Darlow, S. D., Apr 2019, In : JNCCN Journal of the National Comprehensive Cancer Network. 17, 4, p. 302-310 9 p.

Research output: Contribution to journalArticle

41 Scopus citations

Highly Aggressive and Radiation-Resistant, "atypical" and Silent Pituitary Corticotrophic Carcinoma: A Case Report and Review of the Literature

Flores, L., Sleightholm, R., Neilsen, B., Baine, M., Drincic, A., Thorell, W., Shonka, N., Oupicky, D. & Zhang, C., Jan 1 2019, In : Case Reports in Oncology. 12, 1, p. 139-146 8 p.

Research output: Contribution to journalReview article

Open Access

Hospital Regional Network Formation and ‘Brand Sharing’: Appearances May Be Deceiving

Reames, B. N., Anaya, D. A. & Are, C., Mar 15 2019, In : Annals of Surgical Oncology. 26, 3, p. 711-713 3 p.

Research output: Contribution to journalComment/debate

Human bronchial carcinoid tumor initiating cells are targeted by the combination of acetazolamide and sulforaphane

Mokhtari, R. B., Baluch, N., Morgatskaya, E., Kumar, S., Sparaneo, A., Muscarella, L. A., Zhao, S., Cheng, H. L., Das, B. & Yeger, H., Aug 30 2019, In : BMC cancer. 19, 1, 864.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
6 Scopus citations

IL1RL1 is dynamically expressed on Cbfb-MYH11 + leukemia stem cells and promotes cell survival

Wang, Y., Richter, L., Becker, M., Amador, C. & Hyde, R. K., Dec 1 2019, In : Scientific reports. 9, 1, 1729.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

Immunogenicity and efficacy evaluation of subunit astrovirus vaccines

Bidokhti, M. R. M., Ullman, K., Hammer, A. S., Jensen, T. H., Chriél, M., Byrareddy, S. N. & Baule, C., Sep 2019, In : Vaccines. 7, 3, 79.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Immunometabolic alterations by HPV infection: New dimensions to head and neck cancer disparity

Chaudhary, S., Ganguly, K., Muniyan, S., Pothuraju, R., Sayed, Z., Jones, D. T., Batra, S. K. & Macha, M. A., 2019, In : Journal of the National Cancer Institute. 111, 3, p. 233-244 12 p.

Research output: Contribution to journalReview article

Open Access
4 Scopus citations

Increased Survival by Pulmonary Treatment of Established Lung Metastases with Dual STAT3/CXCR4 Inhibition by siRNA Nanoemulsions

Li, Z., Chen, G., Ding, L., Wang, Y., Zhu, C., Wang, K., Li, J., Sun, M. & Oupicky, D., Dec 4 2019, In : Molecular Therapy. 27, 12, p. 2100-2110 11 p.

Research output: Contribution to journalArticle

1 Scopus citations

Induced neural progenitor cells abundantly secrete extracellular vesicles and promote the proliferation of neural progenitors via extracellular signal–regulated kinase pathways

Ma, Y., Wang, K., Pan, J., Fan, Z., Tian, C., Deng, X., Ma, K., Xia, X., Huang, Y. & Zheng, J. C., Apr 2019, In : Neurobiology of Disease. 124, p. 322-334 13 p.

Research output: Contribution to journalArticle

8 Scopus citations

Inhibition of geranylgeranyl diphosphate synthase is a novel therapeutic strategy for pancreatic ductal adenocarcinoma

Haney, S. L., Varney, M. L., Chhonker, Y. S., Shin, S., Mehla, K., Crawford, A. J., Smith, H. J., Smith, L. M., Murry, D. J., Hollingsworth, M. A. & Holstein, S. A., Jun 27 2019, In : Oncogene. 38, 26, p. 5308-5320 13 p.

Research output: Contribution to journalArticle

6 Scopus citations
Open Access
2 Scopus citations

In situ AFM analysis investigating disassembly of DNA nanoparticles and nanofilms

Zou, Y., Wan, L., Blacklock, J., Xie, L., Carroll, S., Oupicky, D. & Mao, G., 2019, Methods in Molecular Biology. Humana Press Inc., p. 199-209 11 p. (Methods in Molecular Biology; vol. 1943).

Research output: Chapter in Book/Report/Conference proceedingChapter

Integration of Genomic and Transcriptional Features in Pancreatic Cancer Reveals Increased Cell Cycle Progression in Metastases

Connor, A. A., Denroche, R. E., Jang, G. H., Lemire, M., Zhang, A., Chan-Seng-Yue, M., Wilson, G., Grant, R. C., Merico, D., Lungu, I., Bartlett, J. M. S., Chadwick, D., Liang, S. B., Eagles, J., Mbabaali, F., Miller, J. K., Krzyzanowski, P., Armstrong, H., Luo, X., Jorgensen, L. G. T. & 25 others, Romero, J. M., Bavi, P., Fischer, S. E., Serra, S., Hafezi-Bakhtiari, S., Caglar, D., Roehrl, M. H. A., Cleary, S., Hollingsworth, M. A., Petersen, G. M., Thayer, S., Law, C. H. L., Nanji, S., Golan, T., Smith, A. L., Borgida, A., Dodd, A., Hedley, D., Wouters, B. G., O'Kane, G. M., Wilson, J. M., Zogopoulos, G., Notta, F., Knox, J. J. & Gallinger, S., Feb 11 2019, In : Cancer Cell. 35, 2, p. 267-282.e7

Research output: Contribution to journalArticle

20 Scopus citations

Intrahepatic Cholangiocarcinoma: Rising Burden and Glaring Disparities

Yanala, U., Malhotra, G., Are, C. & Padussis, J., Jul 15 2019, In : Annals of Surgical Oncology. 26, 7, p. 1979-1980 2 p.

Research output: Contribution to journalEditorial

Open Access
3 Scopus citations

KIBRA controls exosome secretion via inhibiting the proteasomal degradation of Rab27a

Song, L., Tang, S., Han, X., Jiang, Z., Dong, L., Liu, C., Liang, X., Dong, J., Qiu, C., Wang, Y. & Du, Y., Dec 1 2019, In : Nature communications. 10, 1, 1639.

Research output: Contribution to journalArticle

Open Access
14 Scopus citations
Open Access

Label-free characterization of exosome via surface enhanced Raman spectroscopy for the early detection of pancreatic cancer

Carmicheal, J., Hayashi, C., Huang, X., Liu, L., Lu, Y., Krasnoslobodtsev, A., Lushnikov, A., Kshirsagar, P. G., Patel, A., Jain, M., Lyubchenko, Y. L., Lu, Y., Batra, S. K. & Kaur, S., Feb 2019, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 16, p. 88-96 9 p.

Research output: Contribution to journalArticle

15 Scopus citations

Lactate-mediated epigenetic reprogramming regulates formation of human pancreatic cancer-associated fibroblasts

Bhagat, T. D., Von Ahgrens, D., Dawlaty, M., Zou, Y., Baddour, J., Achreja, A., Zhao, H., Yang, L., Patel, B., Kwak, C., Choudhary, G. S., Gordon-Mitchell, S., Alluri, S., Bhattacharyya, S., Sahu, S., Yu, Y., Bartenstein, M., Giricz, O., Suzuki, M., Sohal, D. & 12 others, Gupta, S., Guerrero, P., Batra, S., Goggins, M., Steidl, U., Greally, J., Agarwal, B., Pradhan, K., Banerjee, D., Nagrath, D., Maitra, A. & Verma, A., Oct 2019, In : eLife. 8, e50663.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations

Large expert-curated database for benchmarking document similarity detection in biomedical literature search

RELISH Consortium, 2019, In : Database. 2019, p. 1-67 67 p.

Research output: Contribution to journalArticle

Open Access

Less is more: creation and validation of a novel, affordable suturing simulator for anorectal surgery

Langenfeld, S. J., Fuglestad, M. A., Cologne, K. G., Thompson, J. S., Are, C. & Steele, S. R., Nov 1 2019, In : Techniques in Coloproctology. 23, 11, p. 1057-1064 8 p.

Research output: Contribution to journalArticle

LIMD1 phosphorylation in mitosis is required for mitotic progression and its tumor-suppressing activity

Zhou, J., Zhang, L., Zhou, W., Chen, Y., Cheng, Y. & Dong, J., Mar 2019, In : FEBS Journal. 286, 5, p. 963-974 12 p.

Research output: Contribution to journalArticle

1 Scopus citations

Lipid droplet size directs lipolysis and lipophagy catabolism in hepatocytes

Schott, M. B., Weller, S. G., Schulze, R. J., Krueger, E. W., Drizyte-Miller, K., Casey, C. A. & McNiven, M. A., Oct 7 2019, In : Journal of Cell Biology. 218, 10, p. 3320-3335 16 p.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations

Lipophagy and alcohol-induced fatty liver

Yang, L., Yang, C., Thomes, P. G., Kharbanda, K. K., Casey, C. A., McNiven, M. A. & Donohue, T. M., 2019, In : Frontiers in Pharmacology. 10, MAY, 495.

Research output: Contribution to journalReview article

Open Access
6 Scopus citations