Research Output

2018
8 Scopus citations

Loss of the nuclear pool of Ubiquitin ligase CHIP/STUB1 in breast cancer unleashes the MZF1-cathepsin pro-oncogenic program

Luan, H., Mohapatra, B., Bielecki, T. A., Mushtaq, I., Mirza, S., Jennings, T. A., Clubb, R. J., An, W., Ahmed, D., El-Ansari, R., Storck, M. D., Mishra, N. K., Guda, C., Sheinin, Y. M., Meza, J. L., Raja, S., Rakha, E. A., Band, V. & Band, H., May 15 2018, In : Cancer Research. 78, 10, p. 2524-2535 12 p.

Research output: Contribution to journalArticle

9 Scopus citations

Macrophage-derived neuropilin-2 exhibits novel tumor-promoting functions

Roy, S., Bag, A. K., Dutta, S., Polavaram, N. S., Islam, R., Schellenburg, S., Banwait, J., Guda, C., Ran, S., Hollingsworth, M. A., Singh, R. K., Talmadge, J. E., Muders, M. H., Batra, S. K. & Datta, K., Oct 1 2018, In : Cancer Research. 78, 19, p. 5600-5617 18 p.

Research output: Contribution to journalArticle

8 Scopus citations

MASTL induces Colon Cancer progression and Chemoresistance by promoting Wnt/β-catenin signaling

Uppada, S. B., Gowrikumar, S., Ahmad, R., Kumar, B., Szeglin, B., Chen, X., Smith, J. J., Batra, S. K., Singh, A. B. & Dhawan, P., Aug 1 2018, In : Molecular cancer. 17, 1, 111.

Research output: Contribution to journalArticle

14 Scopus citations

Metastatic cancers promote cachexia through ZIP14 upregulation in skeletal muscle

Wang, G., Biswas, A. K., Ma, W., Kandpal, M., Coker, C., Grandgenett, P. M., Hollingsworth, M. A., Jain, R., Tanji, K., López-Pintado, S., Borczuk, A., Hebert, D., Jenkitkasemwong, S., Hojyo, S., Davuluri, R. V., Knutson, M. D., Fukada, T. & Acharyya, S., Jun 1 2018, In : Nature Medicine. 24, 6, p. 770-781 12 p.

Research output: Contribution to journalArticle

31 Scopus citations

Met receptor inhibitor SU11274 localizes in the endoplasmic reticulum

Wiest, E. J., Smith, H. J. & Hollingsworth, M. A., Jul 2 2018, In : Biochemical and Biophysical Research Communications. 501, 4, p. 858-862 5 p.

Research output: Contribution to journalArticle

1 Scopus citations

Microscale Gene Expression Analysis of Tumor-Associated Macrophages

Attri, K. S., Mehla, K., Shukla, S. K. & Singh, P. K., Dec 1 2018, In : Scientific reports. 8, 1, 2408.

Research output: Contribution to journalArticle

3 Scopus citations

miR-106b-responsive gene landscape identifies regulation of Kruppel-like factor family

Wehrkamp, C. J., Natarajan, S. K., Mohr, A. M., Phillippi, M. A. & Mott, J. L., Mar 4 2018, In : RNA Biology. 15, 3, p. 391-403 13 p.

Research output: Contribution to journalArticle

2 Scopus citations

Model for prioritization of Graduate Medical Education funding at a university setting – Engagement of GME committee with the Clinical Enterprise

Are, C., Suh, M., Carpenter, L., Stoddard, H., Hamm, V., DeVries, M., Goldner, W., Jarzynka, K., Parker, J., Simonson, J., Talmon, G., Vokoun, C., Gold, J., Mercer, D. & Wadman, M., Jul 2018, In : American journal of surgery. 216, 1, p. 147-154 8 p.

Research output: Contribution to journalArticle

Motifome comparison between modern human, Neanderthal and Denisovan

Cserhati, M. F., Mooter, M. E., Peterson, L., Wicks, B., Xiao, P., Pauley, M. A. & Guda, C., Jun 18 2018, In : BMC genomics. 19, 1, 472.

Research output: Contribution to journalArticle

2 Scopus citations

MUC16 as a novel target for cancer therapy

Aithal, A., Rauth, S., Kshirsagar, P., Shah, A., Lakshmanan, I., Junker, W. M., Jain, M., Ponnusamy, M. P. & Batra, S. K., Aug 3 2018, In : Expert Opinion on Therapeutic Targets. 22, 8, p. 675-686 12 p.

Research output: Contribution to journalReview article

11 Scopus citations

Multimodal theranostic nanoformulations permit magnetic resonance bioimaging of antiretroviral drug particle tissue-cell biodistribution

Kevadiya, B. D., Woldstad, C., Ottemann, B. M., Dash, P., Sajja, B. R., Lamberty, B., Morsey, B., Kocher, T., Dutta, R., Bade, A. N., Liu, Y., Callen, S. E., Fox, H. S., Byrareddy, S. N., McMillan, J. E. M., Bronich, T. K., Edagwa, B. J., Boska, M. D. & Gendelman, H. E., Jan 1 2018, In : Theranostics. 8, 1, p. 256-276 21 p.

Research output: Contribution to journalArticle

22 Scopus citations

N-Acetyl Cysteine Treatment Restores Early Phase Fracture Healing in Ethanol-Fed Rats

Duryee, M. J., Dusad, A., Hunter, C. D., Kharbanda, K., Bruenjes, J. D., Easterling, K. C., Siebler, J. C., Thiele, G. M. & Chakkalakal, D. A., Jul 2018, In : Alcoholism: Clinical and Experimental Research. 42, 7, p. 1206-1216 11 p.

Research output: Contribution to journalArticle

1 Scopus citations

Natural products: A hope for glioblastoma patients

Vengoji, R., Macha, M. A., Batra, S. K. & Shonka, N. A., Apr 24 2018, In : Oncotarget. 9, 31, p. 22199-22224 26 p.

Research output: Contribution to journalReview article

21 Scopus citations

Near-infrared light-activated IR780-loaded liposomes for anti-tumor angiogenesis and Photothermal therapy

Yang, X., Li, H., Qian, C., Guo, Y., Li, C., Gao, F., Yang, Y., Wang, K., Oupicky, D. & Sun, M., Oct 2018, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 14, 7, p. 2283-2294 12 p.

Research output: Contribution to journalArticle

10 Scopus citations

Neuroethics Questions to Guide Ethical Research in the International Brain Initiatives

Global Neuroethics Summit Delegates, Oct 10 2018, In : Neuron. 100, 1, p. 19-36 18 p.

Research output: Contribution to journalReview article

18 Scopus citations

Newborn blood DNA epigenetic variations and signaling pathway genes associated with Tetralogy of Fallot (TOF)

Radhakrishna, U., Vishweswaraiah, S., Veerappa, A. M., Zafra, R., Albayrak, S., Sitharam, P. H., Saiyed, N. M., Mishra, N. K., Guda, C. & Bahado-Singh, R., Sep 2018, In : PloS one. 13, 9, e0203893.

Research output: Contribution to journalArticle

6 Scopus citations

Normalization of cell associated antiretroviral drug concentrations with a novel RPP30 droplet digital PCR assay

Dyavar, S. R., Ye, Z., Byrareddy, S. N., Scarsi, K. K., Winchester, L. C., Weinhold, J. A., Fletcher, C. V. & Podany, A. T., Dec 1 2018, In : Scientific reports. 8, 1, 3626.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Novel CIL-102 derivatives as potential therapeutic agents for docetaxel-resistant prostate cancer

Miller, D. R., Tzeng, C. C., Farmer, T., Keller, E. T., Caplan, S., Chen, Y. S., Chen, Y. L. & Lin, M. F., Nov 1 2018, In : Cancer Letters. 436, p. 96-108 13 p.

Research output: Contribution to journalArticle

4 Scopus citations

Novel role of O-glycosyltransferases GALNT3 and B3GNT3 in the self-renewal of pancreatic cancer stem cells

Barkeer, S., Chugh, S., Karmakar, S., Kaushik, G., Rauth, S., Rachagani, S., Batra, S. K. & Ponnusamy, M. P., Nov 22 2018, In : BMC cancer. 18, 1, 1157.

Research output: Contribution to journalArticle

7 Scopus citations

Novel strategy to adapt simian-human immunodeficiency virus e1 carrying env from an rv144 volunteer to rhesus macaques: Coreceptor switch and final recovery of a pathogenic virus with exclusive r5 tropism

Scinto, H. B., Gupta, S., Thorat, S., Mukhtar, M. M., Griffiths, A., Delgado, J., Plake, E., Vyas, H. K., Strickland, A., Byrareddy, S. N., Montefiori, D. C., LaBranche, C., Pal, R., Treece, J., Orndorff, S., Ferrari, M. G., Weiss, D., Chenine, A. L., McLinden, R., Michael, N. & 6 others, Kim, J. H., Robb, M. L., Rerks-Ngarm, S., Pitisuttithum, P., Nitayaphan, S. & Ruprecht, R. M., Jul 1 2018, In : Journal of virology. 92, 14, e02222-17.

Research output: Contribution to journalArticle

1 Scopus citations

Omega-3 fatty acids prevent early pancreatic carcinogenesis via repression of the AKT pathway

Ding, Y., Mullapudi, B., Torres, C., Mascariñas, E., Mancinelli, G., Diaz, A. M., McKinney, R., Barron, M., Schultz, M., Heiferman, M., Wojtanek, M., Adrian, K., DeCant, B., Rao, S., Ouellette, M., Tsao, M. S., Bentrem, D. J. & Grippo, P. J., Sep 12 2018, In : Nutrients. 10, 9, 1289.

Research output: Contribution to journalArticle

4 Scopus citations

Oncotargeting by Vesicular Stomatitis Virus (VSV): Advances in cancer therapy

Bishnoi, S., Tiwari, R., Gupta, S., Byrareddy, S. N. & Nayak, D., Feb 23 2018, In : Viruses. 10, 2, 90.

Research output: Contribution to journalReview article

16 Scopus citations

Organoid profiling identifies common responders to chemotherapy in pancreatic cancer

Tiriac, H., Belleau, P., Engle, D. D., Plenker, D., Deschênes, A., Somerville, T. D. D., Froeling, F. E. M., Burkhart, R. A., Denroche, R. E., Jang, G. H., Miyabayashi, K., Young, C. M., Patel, H., Ma, M., Lacomb, J. F., Palmaira, R. L. D., Javed, A. A., Huynh, J. C., Johnson, M., Arora, K. & 50 others, Robine, N., Shah, M., Sanghvi, R., Goetz, A. B., Lowder, C. Y., Martello, L., Driehuis, E., Lecomte, N., Askan, G., Iacobuzio-Donahue, C. A., Clevers, H., Wood, L. D., Hruban, R. H., Thompson, E., Aguirre, A. J., Wolpin, B. M., Sasson, A., Kim, J., Wu, M., Bucobo, J. C., Allen, P., Sejpal, D. V., Nealon, W., Sullivan, J. D., Winter, J. M., Gimotty, P. A., Grem, J. L., Dimaio, D. J., Buscaglia, J. M., Grandgenett, P. M., Brody, J. R., Hollingsworth, M. A., O’kane, G. M., Notta, F., Kim, E., Crawford, J. M., Devoe, C., Ocean, A., Wolfgang, C. L., Yu, K. H., Li, E., Vakoc, C. R., Hubert, B., Fischer, S. E., Wilson, J. M., Moffitt, R., Knox, J., Krasnitz, A., Gallinger, S. & Tuveson, D. A., Sep 2018, In : Cancer Discovery. 8, 9, p. 1112-1129 18 p.

Research output: Contribution to journalArticle

116 Scopus citations
3 Scopus citations

p66Shc regulates migration of castration-resistant prostate cancer cells

Ingersoll, M. A., Chou, Y. W., Lin, J. S., Yuan, T. C., Miller, D. R., Xie, Y., Tu, Y., Oberley-Deegan, R. E., Batra, S. K. & Lin, M. F., Jun 2018, In : Cellular Signalling. 46, p. 1-14 14 p.

Research output: Contribution to journalArticle

8 Scopus citations

Pancreatic cancer associated with obesity and diabetes: An alternative approach for its targeting

Pothuraju, R., Rachagani, S., Junker, W. M., Chaudhary, S., Saraswathi, V., Kaur, S. & Batra, S. K., Dec 19 2018, In : Journal of Experimental and Clinical Cancer Research. 37, 1, 319.

Research output: Contribution to journalReview article

16 Scopus citations

Pathological and functional significance of Semaphorin-5A in pancreatic cancer progression and metastasis

Saxena, S., Hayashi, Y., Wu, L., Awaji, M., Atri, P., Varney, M. L., Purohit, A., Rachagani, S., Batra, S. K. & Singh, R. K., Jan 1 2018, In : Oncotarget. 9, 5, p. 5931-5943 13 p.

Research output: Contribution to journalArticle

10 Scopus citations

PD2/PAF1 at the crossroads of the cancer network

Karmakar, S., Dey, P., Vaz, A. P., Bhaumik, S. R., Ponnusamy, M. P. & Batra, S. K., Jan 15 2018, In : Cancer Research. 78, 2, p. 313-319 7 p.

Research output: Contribution to journalReview article

6 Scopus citations

PD-L1, inflammation, non-coding RNAs, and neuroblastoma: Immuno-oncology perspective

Nallasamy, P., Chava, S., Verma, S. S., Mishra, S., Gorantla, S., Coulter, D. W., Byrareddy, S. N., Batra, S. K., Gupta, S. C. & Challagundla, K. B., Oct 2018, In : Seminars in Cancer Biology. 52, p. 53-65 13 p.

Research output: Contribution to journalReview article

9 Scopus citations

Pharmacokinetics and efficacy of orally administered polymeric chloroquine as macromolecular drug in the treatment of inflammatory bowel disease

Kanvinde, S., Chhonker, Y. S., Ahmad, R., Yu, F., Sleightholm, R., Tang, W., Jaramillo, L., Chen, Y., Sheinin, Y., Li, J., Murry, D. J., Singh, A. B. & Oupicky, D., Dec 2018, In : Acta Biomaterialia. 82, p. 158-170 13 p.

Research output: Contribution to journalArticle

1 Scopus citations

Phosphoinositide 3-kinase signaling pathway in pancreatic ductal adenocarcinoma progression, pathogenesis, and therapeutics

Murthy, D., Attri, K. S. & Singh, P. K., Apr 4 2018, In : Frontiers in Physiology. 9, APR, 335.

Research output: Contribution to journalReview article

14 Scopus citations

Polymeric micelleplexes for improved photothermal endosomal escape and delivery of siRNA

Chen, G., Ding, L., Wu, P., Zhou, Y., Sun, M., Wang, K. & Oupický, D., Oct 2018, In : Polymers for Advanced Technologies. 29, 10, p. 2593-2600 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

Polymeric Prodrugs Targeting Polyamine Metabolism Inhibit Zika Virus Replication

Routhu, N. K., Xie, Y., Dunworth, M., Casero, R. A., Oupicky, D. & Byrareddy, S. N., Sep 4 2018, In : Molecular Pharmaceutics. 15, 9, p. 4284-4295 12 p.

Research output: Contribution to journalArticle

3 Scopus citations

Precision Medicine for CRC Patients in the Veteran Population: State-of-the-Art, Challenges and Research Directions

Mohapatra, S. S., Batra, S. K., Bharadwaj, S., Bouvet, M., Cosman, B., Goel, A., Jogunoori, W., Kelley, M. J., Mishra, L., Mishra, B., Mohapatra, S., Patel, B., Pisegna, J. R., Raufman, J. P., Rao, S., Roy, H., Scheuner, M., Singh, S., Vidyarthi, G. & White, J., May 1 2018, In : Digestive Diseases and Sciences. 63, 5, p. 1123-1138 16 p.

Research output: Contribution to journalReview article

4 Scopus citations

Preliminary studies on immune response and viral pathogenesis of zika virus in rhesus macaques

Woollard, S. M., Olwenyi, O. A., Dutta, D., Dave, R. S., Mathews, S., Gorantla, S., Johnson, N., Giavedoni, L., Norgren, R. B. & Byrareddy, S. N., Sep 2018, In : Pathogens. 7, 3, 70.

Research output: Contribution to journalArticle

4 Scopus citations

Probing the self-assembly dynamics and internal structure of amphiphilic hyaluronic acid conjugates by fluorescence spectroscopy and molecular dynamics simulations

Svechkarev, D., Kyrychenko, A., Payne, W. M. & Mohs, A. M., Jan 1 2018, In : Soft Matter. 14, 23, p. 4762-4771 10 p.

Research output: Contribution to journalArticle

9 Scopus citations

Protein–protein interactions with connexin 43: Regulation and function

Sorgen, P. L., Trease, A. J., Spagnol, G., Delmar, M. & Nielsen, M. S., May 10 2018, In : International journal of molecular sciences. 19, 5, 1428.

Research output: Contribution to journalReview article

20 Scopus citations

Proteomic profiling of HIV-infected T-cells by SWATH mass spectrometry

DeBoer, J., Wojtkiewicz, M. S., Haverland, N., Li, Y., Harwood, E., Leshen, E., George, J. W., Ciborowski, P. & Belshan, M., Mar 2018, In : Virology. 516, p. 246-257 12 p.

Research output: Contribution to journalArticle

1 Scopus citations

Pulmonary delivery of polyplexes for combined PAI-1 gene silencing and CXCR4 inhibition to treat lung fibrosis

Ding, L., Zhu, C., Yu, F., Wu, P., Chen, G., Ullah, A., Wang, K., Sun, M., Li, J. & Oupický, D., Aug 2018, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 14, 6, p. 1765-1776 12 p.

Research output: Contribution to journalArticle

5 Scopus citations

Ramifications of secreted mucin MUC5AC in malignant journey: A holistic view

Krishn, S. R., Ganguly, K., Kaur, S. & Batra, S. K., Jan 1 2018, In : Carcinogenesis. 39, 5, p. 633-651 19 p.

Research output: Contribution to journalReview article

4 Scopus citations

Ratiometric Fluorescent Sensor Array as a Versatile Tool for Bacterial Pathogen Identification and Analysis

Svechkarev, D., Sadykov, M. R., Bayles, K. W. & Mohs, A. M., Mar 23 2018, In : ACS Sensors. 3, 3, p. 700-708 9 p.

Research output: Contribution to journalArticle

17 Scopus citations

Redox manipulation of the manganese metal in human manganese superoxide dismutase for neutron diffraction

Azadmanesh, J., Lutz, W. E., Weiss, K. L., Coates, L. & Borgstahl, G. E. O., Oct 2018, In : Acta Crystallographica Section F: Structural Biology Communications. 74, 10, p. 677-687 11 p.

Research output: Contribution to journalArticle

4 Scopus citations

Relationship of procedural numbers with meaningful procedural autonomy in general surgery residents

Stride, H. P., George, B. C., Williams, R. G., Bohnen, J. D., Eaton, M. J., Schuller, M. C., Zhao, L., Yang, A., Meyerson, S. L., Scully, R., Dunnington, G. L., Torbeck, L., Mullen, J. T., Mandell, S. P., Choti, M., Foley, E., Are, C., Auyang, E., Chipman, J., Choi, J. & 9 others, Meier, A., Smink, D., Terhune, K. P., Wise, P., DaRosa, D., Soper, N., Zwischenberger, J. B., Lillemoe, K. & Fryer, J. P., Mar 2018, In : Surgery (United States). 163, 3, p. 488-494 7 p.

Research output: Contribution to journalArticle

20 Scopus citations

Response: "we Still in an Update Process of the BCLC System"

Dhir, M. & Are, C., Feb 1 2018, In : Annals of surgery. 267, 2, p. e24-e25

Research output: Contribution to journalLetter

1 Scopus citations

Response to Letter: Hepatocellular Carcinoma: The Gap between Eastern and Western Clinical Practice

Dhir, M. & Are, C., Feb 1 2018, In : Annals of surgery. 267, 2, p. e28-e29

Research output: Contribution to journalLetter

Reversible Covalent Cross-Linked Polycations with Enhanced Stability and ATP-Responsive Behavior for Improved siRNA Delivery

Zhou, Z., Zhang, M., Liu, Y., Li, C., Zhang, Q., Oupicky, D. & Sun, M., Sep 10 2018, In : Biomacromolecules. 19, 9, p. 3776-3787 12 p.

Research output: Contribution to journalArticle

17 Scopus citations

Reversibly Stabilized Polycation Nanoparticles for Combination Treatment of Early- and Late-Stage Metastatic Breast Cancer

Chen, G., Wang, Y., Wu, P., Zhou, Y., Yu, F., Zhu, C., Li, Z., Hang, Y., Wang, K., Li, J., Sun, M. & Oupicky, D., Jul 24 2018, In : ACS Nano. 12, 7, p. 6620-6636 17 p.

Research output: Contribution to journalArticle

12 Scopus citations

Role of nutrition in alcoholic liver disease: Summary of the symposium at the ESBRA 2017 congress

Kharbanda, K. K., Ronis, M. J. J., Shearn, C. T., Petersen, D. R., Zakhari, S., Warner, D. R., Feldstein, A. E., McClain, C. J. & Kirpich, I. A., Jun 2018, In : Biomolecules. 8, 2, 16.

Research output: Contribution to journalArticle

3 Scopus citations

Role of preoperative biliary stenting and preoperative preparation before pancreaticoduodenectomy

Batra, R. & Are, C., Jun 1 2018, Surgery for Pancreatic and Periampullary Cancer: Principles and Practice. Springer Singapore, p. 57-64 8 p.

Research output: Chapter in Book/Report/Conference proceedingChapter