Research Output

2018

Role of the EHD Family of Endocytic Recycling Regulators for TCR Recycling and T Cell Function

Iseka, F. M., Goetz, B. T., Mushtaq, I., An, W., Cypher, L. R., Bielecki, T. A., Tom, E. C., Arya, P., Bhattacharyya, S., Storck, M. D., Semerad, C. L., Talmadge, J. E., Mosley, R. L., Band, V. & Band, H., Jan 15 2018, In : Journal of Immunology. 200, 2, p. 483-499 17 p.

Research output: Contribution to journalArticle

3 Scopus citations

Select gp120 V2 domain specific antibodies derived from HIV and SIV infection and vaccination inhibit gp120 binding to α4β7

Lertjuthaporn, S., Cicala, C., Van Ryk, D., Liu, M., Yolitz, J., Wei, D., Nawaz, F., Doyle, A., Horowitch, B., Park, C., Lu, S., Lou, Y., Wang, S., Pan, R., Jiang, X., Villinger, F., Byrareddy, S. N., Santangelo, P. J., Morris, L., Wibmer, C. K. & 15 others, Biris, K., Mason, R. D., Gorman, J., Hiatt, J., Martinelli, E., Roederer, M., Fujikawa, D., Gorini, G., Franchini, G., Arakelyan, A., Ansari, A. A., Pattanapanyasat, K., Kong, X. P., Fauci, A. S. & Arthos, J., Aug 2018, In : PLoS pathogens. 14, 8, e1007278.

Research output: Contribution to journalArticle

11 Scopus citations

Semaphorin-5A maintains epithelial phenotype of malignant pancreatic cancer cells

Saxena, S., Purohit, A., Varney, M. L., Hayashi, Y. & Singh, R. K., Dec 22 2018, In : BMC cancer. 18, 1, 1283.

Research output: Contribution to journalArticle

6 Scopus citations

Sepiapterin alleviates impaired gastric nNOS function in spontaneous diabetic female rodents through NRF2 mRNA turnover and miRNA biogenesis pathway

Gangula, P. R., Challagundla, K. B., Ravella, K., Mukhopadhyay, S., Chinnathambi, V., Mittal, M. K., Sekhar, K. R. & Sampath, C., Dec 2018, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 315, 6, p. G980-G990

Research output: Contribution to journalArticle

3 Scopus citations
7 Scopus citations

Site-directed non-covalent polymer-drug complexes for inflammatory bowel disease (IBD): Formulation development, characterization and pharmacological evaluation

Kesharwani, S. S., Ahmad, R., Bakkari, M. A., Rajput, M. K. S., Dachineni, R., Valiveti, C. K., Kapur, S., Jayarama Bhat, G., Singh, A. B. & Tummala, H., Nov 28 2018, In : Journal of Controlled Release. 290, p. 165-179 15 p.

Research output: Contribution to journalArticle

18 Scopus citations

SIV/SHIV-Zika co-infection does not alter disease pathogenesis in adult non-pregnant rhesus macaque model

Bidokhti, M. R. M., Dutta, D., Madduri, L. S. V., Woollard, S. M., Norgren, R., Giavedoni, L. & Byrareddy, S. N., Oct 2018, In : PLoS neglected tropical diseases. 12, 10, e0006811.

Research output: Contribution to journalArticle

4 Scopus citations

Size Matters: Metastatic Cluster Size and Stromal Recruitment in the Establishment of Successful Prostate Cancer to Bone Metastases

Araujo, A., Cook, L. M., Lynch, C. C. & Basanta, D., May 1 2018, In : Bulletin of Mathematical Biology. 80, 5, p. 1046-1058 13 p.

Research output: Contribution to journalArticle

2 Scopus citations

Staphylococcal enzymes and virulence

Ciborowski, P. & Jeljaszewicz, J., Jan 1 2018, Bacterial Enzymes and Virulence. CRC Press, p. 145-183 39 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Superoxide dismutases (SODs) and SOD mimetics

Borgstahl, G. E. O. & Oberley-Deegan, R. E., Nov 2 2018, In : Antioxidants. 7, 11, 156.

Research output: Contribution to journalEditorial

3 Scopus citations

Synthesis and Evaluation of Chloroquine-Containing DMAEMA Copolymers as Efficient Anti-miRNA Delivery Vectors with Improved Endosomal Escape and Antimigratory Activity in Cancer Cells

Xie, Y., Yu, F., Tang, W., Alade, B. O., Peng, Z. H., Wang, Y., Li, J. & Oupický, D., Jan 2018, In : Macromolecular Bioscience. 18, 1, 1700194.

Research output: Contribution to journalArticle

8 Scopus citations

Targeting hypoxia-inducible factor-1a/pyruvate dehydrogenase kinase 1 axis by dichloroacetate suppresses bleomycin-induced pulmonary fibrosis

Goodwin, J., Choi, H., Hsieh, M. H., Neugent, M. L., Ahn, J. M., Hayenga, H. N., Singh, P. K., Shackelford, D. B., Lee, I. K., Shulaev, V., Dhar, S., Takeda, N. & Kim, J. W., Feb 2018, In : American journal of respiratory cell and molecular biology. 58, 2, p. 216-231 16 p.

Research output: Contribution to journalEditorial

20 Scopus citations

The addition of manganese porphyrins during radiation inhibits prostate cancer growth and simultaneously protects normal prostate tissue from radiation damage

Chatterjee, A., Zhu, Y., Tong, Q., Kosmacek, E. A., Lichter, E. Z. & Oberley-Deegan, R. E., Jan 2018, In : Antioxidants. 7, 1, 21.

Research output: Contribution to journalArticle

Open Access
12 Scopus citations

The enigmatic endosome - Sorting the ins and outs of endocytic trafficking

Naslavsky, N. & Caplan, S., Jul 1 2018, In : Journal of cell science. 131, 13, jcs216499.

Research output: Contribution to journalReview article

29 Scopus citations

The influence of medical school on career choice: A longitudinal study of students’ attitudes toward a career in general surgery

Are, C., Stoddard, H. A., Nelson, K. L., Huggett, K., Carpenter, L. & Thompson, J. S., Dec 2018, In : American journal of surgery. 216, 6, p. 1215-1222 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

The loss of α-and β-tubulin proteins are a pathological hallmark of chronic alcohol consumption and natural brain ageing

Labisso, W. L., Raulin, A. C., Nwidu, L. L., Kocon, A., Wayne, D., Erdozain, A. M., Morentin, B., Schwendener, D., Allen, G., Enticott, J., Gerdes, H. K., Johnson, L., Grzeskowiak, J., Drizou, F., Tarbox, R., Osna, N. A., Kharbanda, K. K., Callado, L. F. & Carter, W. G., Sep 11 2018, In : Brain Sciences. 8, 9, 175.

Research output: Contribution to journalArticle

2 Scopus citations

The Relationship Between Age and Chronic Kidney Disease in Patients Undergoing Pancreatic Resection

Antoniak, D., Are, C., Vokoun, C., Samson, K., Smith, L. & Shiffermiller, J., Aug 1 2018, In : Journal of Gastrointestinal Surgery. 22, 8, p. 1376-1384 9 p.

Research output: Contribution to journalArticle

3 Scopus citations

Thermodynamic Stability of DNA Duplexes Comprising the Simplest T → du Substitutions

Carr, C. E., Khutsishvili, I., Gold, B. & Marky, L. A., Oct 2 2018, In : Biochemistry. 57, 39, p. 5666-5671 6 p.

Research output: Contribution to journalArticle

2 Scopus citations

The role of hydrophobic modification on hyaluronic acid dynamics and self-assembly

Payne, W. M., Svechkarev, D., Kyrychenko, A. & Mohs, A. M., Feb 15 2018, In : Carbohydrate Polymers. 182, p. 132-141 10 p.

Research output: Contribution to journalArticle

18 Scopus citations

The Role of Integrin α4β7 in HIV Pathogenesis and Treatment

Arthos, J., Cicala, C., Nawaz, F., Byrareddy, S. N., Villinger, F., Santangelo, P. J., Ansari, A. A. & Fauci, A. S., Apr 1 2018, In : Current HIV/AIDS Reports. 15, 2, p. 127-135 9 p.

Research output: Contribution to journalReview article

12 Scopus citations

Transcriptional profiling using RNA-seq to study hypoxia-mediated gene regulation

Shukla, S. K., King, R. J. & Singh, P. K., Jan 1 2018, Methods in Molecular Biology. Humana Press Inc., p. 55-66 12 p. (Methods in Molecular Biology; vol. 1742).

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Triheptanoin: A rescue therapy for cardiogenic shock in carnitine-acylcarnitine translocase deficiency

Mahapatra, S., Ananth, A., Baugh, N., Damian, M. & Enns, G. M., Jan 1 2018, JIMD Reports. Springer, p. 19-23 5 p. (JIMD Reports; vol. 39).

Research output: Chapter in Book/Report/Conference proceedingChapter

5 Scopus citations

TRPV2 is a novel biomarker and therapeutic target in triple negative breast cancer

Elbaz, M., Ahirwar, D., Xiaoli, Z., Zhou, X., Lustberg, M., Nasser, M. W., Shilo, K. & Ganju, R. K., Sep 1 2018, In : Oncotarget. 9, 71, p. 33459-33470 12 p.

Research output: Contribution to journalArticle

8 Scopus citations

Tying trafficking to fusion and fission at the mighty mitochondria

Farmer, T., Naslavsky, N. & Caplan, S., Aug 2018, In : Traffic. 19, 8, p. 569-577 9 p.

Research output: Contribution to journalReview article

15 Scopus citations

Unfolding and Targeting Thermodynamics of a DNA Intramolecular Complex with Joined Triplex-Duplex Domains

Johnson, S. E., Reiling-Steffensmeier, C., Lee, H. T. & Marky, L. A., Jan 25 2018, In : Journal of Physical Chemistry B. 122, 3, p. 1102-1111 10 p.

Research output: Contribution to journalArticle

Unfolding thermodynamics of nucleic acids: Determining heat capacity effects using differential scanning calorimetry (DSC)

Carr, C. E., Reiling-Steffensmeier, C., Khutsishvili, I. & Marky, L. A., Jan 1 2018, Differential Scanning Calorimetry: Basics and Applications. Nova Science Publishers, Inc., p. 1-41 41 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Vesicular trafficking plays a role in centriole disengagement and duplication

Xie, S., Reinecke, J. B., Farmer, T., Bahl, K., Yeow, I., Nichols, B. J., McLamarrah, T. A., Naslavsky, N., Rogers, G. C. & Caplan, S., Nov 1 2018, In : Molecular biology of the cell. 29, 22, p. 2622-2631 10 p.

Research output: Contribution to journalArticle

5 Scopus citations

WDR5 supports colon cancer cells by promoting methylation of H3K4 and suppressing DNA damage

Neilsen, B. K., Chakraborty, B., McCall, J. L., Frodyma, D. E., Sleightholm, R. L., Fisher, K. W. & Lewis, R. E., Jun 20 2018, In : BMC cancer. 18, 1, 673.

Research output: Contribution to journalArticle

4 Scopus citations

Zika virus propagation and release in human fetal astrocytes can be suppressed by neutral sphingomyelinase-2 inhibitor GW4869

Huang, Y., Li, Y., Zhang, H., Zhao, R., Jing, R., Xu, Y., He, M., Peer, J., Kim, Y. C., Luo, J., Tong, Z. & Zheng, J., Dec 1 2018, In : Cell Discovery. 4, 1, 19.

Research output: Contribution to journalArticle

14 Scopus citations

Zyxin promotes colon cancer tumorigenesis in a mitotic phosphorylation-dependent manner and through CDK8-mediated YAP activation

Zhou, J., Zeng, Y., Cui, L., Chen, X., Stauffer, S., Wang, Z., Yu, F., Lele, S. M., Talmon, G. A., Black, A. R., Chen, Y. & Dong, J., Jul 17 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 29, p. E6760-E6769

Research output: Contribution to journalArticle

8 Scopus citations

英美中三国全科医生培养模式对比研究

Translated title of the contribution: Models for training general practitioners in the uk,u.s. and china:a comparative studyZhao, X. X., Sun, X. T., Pan, Z. G. & Zheng, J. L., Aug 5 2018, In : Chinese General Practice. 21, 22, p. 2660-2663 4 p.

Research output: Contribution to journalArticle

2 Scopus citations
2017

A Combination of MUC5AC and CA19-9 Improves the Diagnosis of Pancreatic Cancer: A Multicenter Study

Kaur, S., Smith, L. M., Patel, A., Menning, M., Watley, D. C., Malik, S. S., Krishn, S. R., Mallya, K., Aithal, A., Sasson, A. R., Johansson, S. L., Jain, M., Singh, S., Guha, S., Are, C., Raimondo, M., Hollingsworth, M. A., Brand, R. E. & Batra, S. K., Jan 1 2017, In : American Journal of Gastroenterology. 112, 1, p. 172-183 12 p.

Research output: Contribution to journalArticle

30 Scopus citations

Acute maternal oxidant exposure causes susceptibility of the fetal brain to inflammation and oxidative stress

Akhtar, F., Rouse, C. A., Catano, G., Montalvo, M., Ullevig, S. L., Asmis, R., Kharbanda, K. & Maffi, S. K., Sep 30 2017, In : Journal of Neuroinflammation. 14, 1, 195.

Research output: Contribution to journalArticle

11 Scopus citations

Afatinib radiosensitizes head and neck squamous cell carcinoma cells by targeting cancer stem cells

Macha, M. A., Rachagani, S., Qazi, A. K., Jahan, R., Gupta, S., Patel, A. A., Seshacharyulu, P., Lin, C., Li, S., Wang, S., Verma, V., Kishida, S., Kishida, M., Nakamura, N., Kibe, T., Lydiatt, W. M., Smith, R. B., Ganti, A. K., Jones, D. T., Batra, S. K. & 1 others, Jain, M., Jan 1 2017, In : Oncotarget. 8, 13, p. 20961-20973 13 p.

Research output: Contribution to journalArticle

18 Scopus citations

Alcohol, microbiome, life style influence alcohol and non-alcoholic organ damage

Neuman, M. G., French, S. W., Zakhari, S., Malnick, S., Seitz, H. K., Cohen, L. B., Salaspuro, M., Voinea-Griffin, A., Barasch, A., Kirpich, I. A., Thomes, P. G., Schrum, L. W., Donohue, T. M., Kharbanda, K. K., Cruz, M. & Opris, M., Feb 1 2017, In : Experimental and Molecular Pathology. 102, 1, p. 162-180 19 p.

Research output: Contribution to journalReview article

16 Scopus citations

Alcoholic liver disease: Pathogenesis and current management

Osna, N. A., Donohue, T. M. & Kharbanda, K. K., Jan 1 2017, In : Alcohol Research: Current Reviews. 38, 2, p. 7-21 15 p.

Research output: Contribution to journalArticle

5 Scopus citations

Alcoholic Liver Disease: Pathogenesis and Current Management

Osna, N. A., Donohue, T. M. & Kharbanda, K. K., Jan 1 2017, In : Alcohol research : current reviews. 38, 2, p. 147-161 15 p.

Research output: Contribution to journalReview article

44 Scopus citations

Amelioration of ongoing experimental autoimmune encephalomyelitis with fluoxetine

Bhat, R., Mahapatra, S., Axtell, R. C. & Steinman, L., Dec 15 2017, In : Journal of Neuroimmunology. 313, p. 77-81 5 p.

Research output: Contribution to journalArticle

10 Scopus citations

Amino acid catabolism in Staphylococcus aureus and the function of carbon catabolite repression

Halsey, C. R., Lei, S., Wax, J. K., Lehman, M. K., Nuxoll, A. S., Steinke, L., Sadykov, M., Powers, R. & Fey, P. D., Jan 1 2017, In : mBio. 8, 1, e01434-16.

Research output: Contribution to journalArticle

41 Scopus citations

A multi-institution analysis of general surgery resident peer-reviewed publication trends

Forrester, J. D., Ansari, P., Are, C., Auyang, E., Galante, J. M., Jarman, B. T., Smith, B. R., Watkins, A. C. & Melcher, M. L., Apr 1 2017, In : Journal of Surgical Research. 210, p. 92-98 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

An essential role of CBL and CBL-B ubiquitin ligases in mammary stem cell maintenance

Mohapatra, B., Zutshi, N., An, W., Goetz, B., Arya, P., Bielecki, T. A., Mustaq, I., Storck, M. D., Meza, J. L., Band, V. & Band, H., Apr 1 2017, In : Journal of Cell Science. 130, 7, p. 1072-1086 15 p.

Research output: Contribution to journalArticle

8 Scopus citations

Anti-fibrotic actions of relaxin

Samuel, C. S., Royce, S. G., Hewitson, T. D., Denton, K. M., Cooney, T. E. & Bennett, R. G., Jan 1 2017, In : British Journal of Pharmacology. 174, 10, p. 962-976 15 p.

Research output: Contribution to journalArticle

42 Scopus citations

Antigen presentation profiling reveals recognition of lymphoma immunoglobulin neoantigens

Khodadoust, M. S., Olsson, N., Wagar, L. E., Haabeth, O. A. W., Chen, B., Swaminathan, K., Rawson, K., Liu, C. L., Steiner, D., Lund, P., Rao, S., Zhang, L., Marceau, C., Stehr, H., Newman, A. M., Czerwinski, D. K., Carlton, V. E. H., Moorhead, M., Faham, M., Kohrt, H. E. & 6 others, Carette, J., Green, M. R., Davis, M. M., Levy, R., Elias, J. E. & Alizadeh, A. A., Mar 30 2017, In : Nature. 543, 7647, p. 723-727 5 p.

Research output: Contribution to journalArticle

98 Scopus citations

Association of distinct mutational signatures with correlates of increased immune activity in pancreatic ductal adenocarcinoma

Connor, A. A., Denroche, R. E., Jang, G. H., Timms, L., Kalimuthu, S. N., Selander, I., McPherson, T., Wilson, G. W., Chan-Seng-Yue, M. A., Borozan, I., Ferretti, V., Grant, R. C., Lungu, I. M., Costello, E., Greenhalf, W., Palmer, D., Ghaneh, P., Neoptolemos, J. P., Buchler, M., Petersen, G. & 20 others, Thayer, S., Hollingsworth, M. A., Sherker, A., Durocher, D., Dhani, N., Hedley, D., Serra, S., Pollett, A., Roehrl, M. H. A., Bavi, P., Bartlett, J. M. S., Cleary, S., Wilson, J. M., Alexandrov, L. B., Moore, M., Wouters, B. G., McPherson, J. D., Notta, F., Stein, L. D. & Gallinger, S., Jun 2017, In : JAMA Oncology. 3, 6, p. 774-783 10 p.

Research output: Contribution to journalArticle

84 Scopus citations

Association of general surgery resident remediation and program director attitudes with resident attrition

Schwed, A. C., Lee, S. L., Salcedo, E. S., Reeves, M. E., Inaba, K., Sidwell, R. A., Amersi, F., Are, C., Arnell, T. D., Damewood, R. B., Dent, D. L., Donahue, T., Gauvin, J., Hartranft, T., Jacobsen, G. R., Jarman, B. T., Melcher, M. L., Mellinger, J. D., Morris, J. B., Nehler, M. & 4 others, Smith, B. R., Wolfe, M., Kaji, A. H. & De Virgilio, C., Dec 2017, In : JAMA Surgery. 152, 12, p. 1134-1140 7 p.

Research output: Contribution to journalArticle

13 Scopus citations

Bifunctional enzyme JMJD6 contributes to multiple disease pathogenesis: New twist on the old story

Vangimalla, S. S., Ganesan, M., Kharbanda, K. K. & Osna, N. A., Jun 2017, In : Biomolecules. 7, 2, 41.

Research output: Contribution to journalReview article

10 Scopus citations

Biochemical evaluation of the anticancer potential of the polyamine-based nanocarrier Nano 11047

Murray-Stewart, T., Ferrari, E., Xie, Y., Yu, F., Marton, L. J., Oupicky, D. & Casero, R. A., Apr 2017, In : PloS one. 12, 4, e0175917.

Research output: Contribution to journalArticle

8 Scopus citations

Biological determinants of radioresistance and their remediation in pancreatic cancer

Seshacharyulu, P., Baine, M. J., Souchek, J. J., Menning, M., Kaur, S., Yan, Y., Ouellette, M. M., Jain, M., Lin, C. & Batra, S. K., Aug 1 2017, In : Biochimica et Biophysica Acta - Reviews on Cancer. 1868, 1, p. 69-92 24 p.

Research output: Contribution to journalReview article

17 Scopus citations

Bioreducible Cross-Linked Hyaluronic Acid/Calcium Phosphate Hybrid Nanoparticles for Specific Delivery of siRNA in Melanoma Tumor Therapy

Zhou, Z., Li, H., Wang, K., Guo, Q., Li, C., Jiang, H., Hu, Y., Oupicky, D. & Sun, M., May 3 2017, In : ACS Applied Materials and Interfaces. 9, 17, p. 14576-14589 14 p.

Research output: Contribution to journalArticle

40 Scopus citations

Cathepsin B Improves ß-Amyloidosis and Learning and Memory in Models of Alzheimer’s Disease

Embury, C. M., Dyavarshetty, B., Lu, Y., Wiederin, J. L., Ciborowski, P., Gendelman, H. E. & Kiyota, T., Jun 1 2017, In : Journal of Neuroimmune Pharmacology. 12, 2, p. 340-352 13 p.

Research output: Contribution to journalArticle

18 Scopus citations