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2020

A comparative analysis of survival and funding discrepancies in cancers with high mortality

Hall, B. R., Cannon, A., Atri, P., Wichman, C. S., Smith, L. M., Kumar, S., Batra, S. K., Wang, H., Ganti, A. K., Sasson, A. R. & Are, C., Feb 1 2020, In : Annals of surgery. 271, 2, p. 296-302 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

A novel pregnene analogs: synthesis, cytotoxicity on prostate cancer of PC-3 and LNCPa-AI cells and in silico molecular docking study

Abdul-Rida, N. A., Farhan, A. M., Al-Masoudi, N. A., Saeed, B. A., Miller, D. & Lin, M. F., Jan 1 2020, (Accepted/In press) In : Molecular Diversity.

Research output: Contribution to journalArticle

A phase I study of weekly doxorubicin and oral topotecan for patients with relapsed or refractory small cell lung cancer (SCLC): A Fred and Pamela Buffet Cancer Center Clinical Trials Network study

Ernani, V., Jahan, R., Smith, L. M., Marr, A. S., Kimbrough, S. E., Kos, M. E., Tijerina, J., Pivovar, S., Lakshmanan, I., Ketcham, M., Rauth, S., Mallya, K., Nasser, M. W., Jain, M., Kessinger, A., Batra, S. K. & Ganti, A. K., 2020, In : Cancer Treatment and Research Communications. 22, 100162.

Research output: Contribution to journalArticle

Open Access

A TFAP2C gene signature is predictive of outcome in HER2-positive breast cancer

Wu, V. T., Kiriazov, B., Koch, K. E., Gu, V. W., Beck, A. C., Borcherding, N., Li, T., Addo, P., Wehrspan, Z. J., Zhang, W., Braun, T. A., Brown, B. J., Band, V., Band, H., Kulak, M. V. & Weigel, R. J., Jan 1 2020, In : Molecular Cancer Research. 18, 1, p. 46-56 11 p.

Research output: Contribution to journalArticle

Curcumin use in ulcerative colitis: Is it ready for prime time? A systematic review and meta-analysis of clinical trials

Chandan, S., Mohan, B. P., Chandan, O. C., Ahmad, R., Challa, A., Tummala, H., Singh, S., Dhawan, P., Ponnada, S., Singh, A. B. & Adler, D. G., Jan 1 2020, In : Annals of Gastroenterology. 33, 1, p. 53-58 6 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Cyclin-dependent kinase 1-mediated phosphorylation of protein kinase N1 promotes anchorage-independent growth and migration

Zeng, R., Wang, Z., Li, X., Chen, Y., Yang, S. & Dong, J., May 2020, In : Cellular Signalling. 69, 109546.

Research output: Contribution to journalArticle

Cyclophilin D Contributes to Anesthesia Neurotoxicity in the Developing Brain

Zhang, Y., Lu, P., Liang, F., Liufu, N., Dong, Y., Zheng, J. C. & Xie, Z., Feb 11 2020, In : Frontiers in Cell and Developmental Biology. 7, 396.

Research output: Contribution to journalArticle

Open Access

Differentiating Peripherally-Located Small Cell Lung Cancer From Non-small Cell Lung Cancer Using a CT Radiomic Approach

Chen, B. T., Chen, Z., Ye, N., Mambetsariev, I., Fricke, J., Daniel, E., Wang, G., Wong, C. W., Rockne, R. C., Colen, R. R., Nasser, M. W., Batra, S. K., Holodny, A. I., Sampath, S. & Salgia, R., Apr 22 2020, In : Frontiers in Oncology. 10, 593.

Research output: Contribution to journalArticle

Open Access

Effects of selected deubiquitinating enzyme inhibitors on the proliferation and motility of lung cancer and mesothelioma cell lines

Mirzapoiazova, T., Pozhitkov, A., Nam, A., Mambetsariev, I., Nelson, M. S., Tan, Y. H. C., Zhang, K., Raz, D., Singhal, S., Nasser, M. W., Kulkarni, P., Batra, S. K., Sattler, M. & Salgia, R., Jul 2020, In : International journal of oncology. 57, 1, p. 80-86 7 p.

Research output: Contribution to journalArticle

EHD1 and RUSC2 control basal epidermal growth factor receptor cell surface expression and recycling

Tom, E. C., Mushtaq, I., Mohapatra, B. C., Luan, H., Bhat, A. M., Zutshi, N., Chakraborty, S., Islam, N., Arya, P., Bielecki, T. A., Iseka, F. M., Bhattacharyya, S., Cypher, L. R., Goetz, B. T., Negi, S. K., Storck, M. D., Rana, S., Barnekow, A., Singh, P. K., Ying, G. & 4 others, Guda, C., Natarajan, A., Band, V. & Banda, H., Apr 1 2020, In : Molecular and cellular biology. 40, 7, e00434.

Research output: Contribution to journalArticle

1 Scopus citations

Endosomolytic and Tumor-Penetrating Mesoporous Silica Nanoparticles for siRNA/miRNA Combination Cancer Therapy

Wang, Y., Xie, Y., Kilchrist, K. V., Li, J., Duvall, C. L. & Oupický, D., Jan 29 2020, In : ACS Applied Materials and Interfaces. 12, 4, p. 4308-4322 15 p.

Research output: Contribution to journalArticle

3 Scopus citations

Fluorescent Sensor Arrays Can Predict and Quantify the Composition of Multicomponent Bacterial Samples

Svechkarev, D., Sadykov, M. R., Houser, L. J., Bayles, K. W. & Mohs, A. M., Jan 15 2020, In : Frontiers in Chemistry. 7, 916.

Research output: Contribution to journalArticle

Open Access

Ghrelin regulates adipose tissue metabolism: Role in hepatic steatosis

Rasineni, K., Kubik, J. L., Knight, K. L., Hall, L., Casey, C. A. & Kharbanda, K. K., May 1 2020, In : Chemico-Biological Interactions. 322, 109059.

Research output: Contribution to journalArticle

1 Scopus citations

Glutaminase 1 Regulates Neuroinflammation After Cerebral Ischemia Through Enhancing Microglial Activation and Pro-Inflammatory Exosome Release

Gao, G., Li, C., Zhu, J., Wang, Y., Huang, Y., Zhao, S., Sheng, S., Song, Y., Ji, C., Li, C., Yang, X., Ye, L., Qi, X., Zhang, Y., Xia, X. & Zheng, J. C., Feb 7 2020, In : Frontiers in immunology. 11, 161.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

High-throughput identification of protein functional similarities using a gene-expression-based siRNA screen

Neilsen, B. K., Kelly, D. L., Chakraborty, B., Kim, H. S., White, M. A., Lewis, R. E. & Fisher, K. W., Dec 1 2020, In : Scientific Data. 7, 1, 27.

Research output: Contribution to journalArticle

Open Access

HLA-B influences integrin beta-1 expression and pancreatic cancer cell migration

Sliker, B. H., Goetz, B. T., Barnes, R., King, H., Maurer, H. C., Olive, K. P. & Solheim, J. C., May 15 2020, In : Experimental Cell Research. 390, 2, 111960.

Research output: Contribution to journalArticle

IL-17–CXC Chemokine Receptor 2 Axis Facilitates Breast Cancer Progression by Up-Regulating Neutrophil Recruitment

Wu, L., Awaji, M., Saxena, S., Varney, M. L., Sharma, B. & Singh, R. K., Jan 2020, In : American Journal of Pathology. 190, 1, p. 222-233 12 p.

Research output: Contribution to journalArticle

Irreversible and sustained upregulation of endothelin axis during oncogene-associated pancreatic inflammation and cancer

Gupta, S., Prajapati, A., Gulati, M., Gautam, S. K., Kumar, S., Dalal, V., Talmon, G. A., Rachagani, S. & Jain, M., Feb 2020, In : Neoplasia (United States). 22, 2, p. 98-110 13 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Linking NRP2 With EMT and Chemoradioresistance in Bladder Cancer

Schulz, A., Gorodetska, I., Behrendt, R., Fuessel, S., Erdmann, K., Foerster, S., Datta, K., Mayr, T., Dubrovska, A. & Muders, M. H., Jan 21 2020, In : Frontiers in Oncology. 9, 1461.

Research output: Contribution to journalArticle

Open Access

Macrophages potentiate STAT3 signaling in skeletal muscles and regulate pancreatic cancer cachexia

Shukla, S. K., Markov, S. D., Attri, K. S., Vernucci, E., King, R. J., Dasgupta, A., Grandgenett, P. M., Hollingsworth, M. A., Singh, P. K., Yu, F. & Mehla, K., Aug 1 2020, In : Cancer Letters. 484, p. 29-39 11 p.

Research output: Contribution to journalArticle

Maturation of Lipophagic Organelles in Hepatocytes Is Dependent Upon a Rab10/Dynamin-2 Complex

Li, Z., Weller, S. G., Drizyte-Miller, K., Chen, J., Krueger, E. W., Mehall, B., Casey, C. A., Cao, H. & McNiven, M. A., Jan 1 2020, (Accepted/In press) In : Hepatology.

Research output: Contribution to journalArticle

Metabolic alterations in pancreatic cancer progression

Vernucci, E., Abrego, J., Gunda, V., Shukla, S. K., Dasgupta, A., Rai, V., Chaika, N., Buettner, K., Illies, A., Yu, F., Lazenby, A. J., Swanson, B. J. & Singh, P. K., Jan 2020, In : Cancers. 12, 1, 2.

Research output: Contribution to journalArticle

Open Access

Metabolic subtyping for novel personalized therapies against pancreatic cancer

Mehla, K. & Singh, P. K., Jan 1 2020, In : Clinical Cancer Research. 26, 1, p. 6-8 3 p.

Research output: Contribution to journalArticle

1 Scopus citations

MiR-1253 exerts tumor-suppressive effects in medulloblastoma via inhibition of CDK6 and CD276 (B7-H3)

Kanchan, R. K., Perumal, N., Atri, P., Chirravuri Venkata, R., Thapa, I., Klinkebiel, D. L., Donson, A. M., Perry, D., Punsoni, M., Talmon, G. A., Coulter, D. W., Boue’, D. R., Snuderl, M., Nasser, M. W., Batra, S. K., Vibhakar, R. & Mahapatra, S., Jan 1 2020, (Accepted/In press) In : Brain Pathology.

Research output: Contribution to journalArticle

miR-15a-5p, miR-15b-5p, and miR-16-5p inhibit tumor progression by directly targeting MYCN in neuroblastoma

Chava, S., Reynolds, C. P., Pathania, A. S., Gorantla, S., Poluektova, L. Y., Coulter, D. W., Gupta, S. C., Pandey, M. K. & Challagundla, K. B., Jan 1 2020, In : Molecular Oncology. 14, 1, p. 180-196 17 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

MnTnBuOE-2-PyP treatment protects from radioactive iodine (I-131) treatment-related side effects in thyroid cancer

Patel, A., Kosmacek, E. A., Fisher, K. W., Goldner, W. & Oberley-Deegan, R. E., Mar 1 2020, In : Radiation and Environmental Biophysics. 59, 1, p. 99-109 11 p.

Research output: Contribution to journalArticle

Open Access

Molecular implications of MUC5AC-CD44 axis in colorectal cancer progression and chemoresistance

Pothuraju, R., Rachagani, S., Krishn, S. R., Chaudhary, S., Nimmakayala, R. K., Siddiqui, J. A., Ganguly, K., Lakshmanan, I., Cox, J. L., Mallya, K., Kaur, S. & Batra, S. K., Feb 25 2020, In : Molecular cancer. 19, 1, 37.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

MUC1 oncoprotein mitigates ER stress via CDA-mediated reprogramming of pyrimidine metabolism

Olou, A. A., King, R. J., Yu, F. & Singh, P. K., Apr 16 2020, In : Oncogene. 39, 16, p. 3381-3395 15 p.

Research output: Contribution to journalArticle

Nanoformulated SOD1 ameliorates the combined NASH and alcoholassociated liver disease partly via regulating CYP2E1 expression in adipose tissue and liver

Gopal, T., Kumar, N., Perriotte-Olson, C., Casey, C. A., Donohue, T. M., Harris, E. N., Talmon, G., Kabanov, A. V. & Saraswathi, V., Jan 1 2020, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 318, 3, p. G428-G438

Research output: Contribution to journalArticle

Neuropilin-2 is an independent prognostic factor for shorter cancer-specific survival in patients with acinar adenocarcinoma of the prostate

Borkowetz, A., Froehner, M., Rauner, M., Conrad, S., Erdmann, K., Mayr, T., Datta, K., Hofbauer, L. C., Baretton, G. B., Wirth, M., Fuessel, S., Toma, M. & Muders, M. H., May 1 2020, In : International Journal of Cancer. 146, 9, p. 2619-2627 9 p.

Research output: Contribution to journalArticle

Open Access

Neutrophils are mediators of metastatic prostate cancer progression in bone

Costanzo-Garvey, D. L., Keeley, T., Case, A. J., Watson, G. F., Alsamraae, M., Yu, Y., Su, K., Heim, C. E., Kielian, T., Morrissey, C., Frieling, J. S. & Cook, L. M., Jun 1 2020, In : Cancer Immunology, Immunotherapy. 69, 6, p. 1113-1130 18 p.

Research output: Contribution to journalArticle

Open Access

Pan-cancer analysis of whole genomes

The ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium, Feb 6 2020, In : Nature. 578, 7793, p. 82-93 12 p.

Research output: Contribution to journalArticle

Open Access
43 Scopus citations

Precision cardiovascular medicine: artificial intelligence and epigenetics for the pathogenesis and prediction of coarctation in neonates

Bahado-Singh, R. O., Vishweswaraiah, S., Aydas, B., Yilmaz, A., Saiyed, N. M., Mishra, N. K., Guda, C. & Radhakrishna, U., Jan 1 2020, (Accepted/In press) In : Journal of Maternal-Fetal and Neonatal Medicine.

Research output: Contribution to journalArticle

Precision medicine and actionable alterations in lung cancer: A single institution experience

Mambetsariev, I., Wang, Y., Chen, C., Nadaf, S., Pharaon, R., Fricke, J., Amanam, I., Amini, A., Bild, A., Chu, P., Erhunmwunsee, L., Kim, J., Munu, J., Pillai, R., Raz, D., Sampath, S., Vora, L., Qiu, F., Smith, L., Batra, S. K. & 4 others, Massarelli, E., Koczywas, M., Reckamp, K. & Salgia, R., Jan 1 2020, In : PloS one. 15, 2, e0228188.

Research output: Contribution to journalArticle

Open Access

Presence and structure-activity relationship of intrinsically disordered regions across mucins

Carmicheal, J., Atri, P., Sharma, S., Kumar, S., Chirravuri Venkata, R., Kulkarni, P., Salgia, R., Ghersi, D., Kaur, S. & Batra, S. K., Feb 1 2020, In : FASEB Journal. 34, 2, p. 1939-1957 19 p.

Research output: Contribution to journalArticle

Open Access

Prognostic and therapeutic implications of NHERF1 expression and regulation in colorectal cancer

Leiphrakpam, P. D., Lazenby, A. J., Chowdhury, S., Smith, L. M., Mathiesen, M., Brattain, M. G., Wang, J., Black, J. D. & Are, C., Mar 1 2020, In : Journal of Surgical Oncology. 121, 3, p. 547-560 14 p.

Research output: Contribution to journalArticle

Proximal tubule cyclophilin D regulates fatty acid oxidation in cisplatin-induced acute kidney injury

Jang, H. S., Noh, M. R., Jung, E. M., Kim, W. Y., Southekal, S., Guda, C., Foster, K. W., Oupicky, D., Ferrer, F. A. & Padanilam, B. J., Feb 2020, In : Kidney International. 97, 2, p. 327-339 13 p.

Research output: Contribution to journalArticle

1 Scopus citations

Radiomics-based outcome prediction for pancreatic cancer following stereotactic body radiotherapy

Parr, E., Du, Q., Zhang, C., Lin, C., Kamal, A., McAlister, J., Liang, X., Bavitz, K., Rux, G., Hollingsworth, M., Baine, M. & Zheng, D., Apr 2020, In : Cancers. 12, 4, 1051.

Research output: Contribution to journalArticle

Open Access

Reprogrammed astrocytes display higher neurogenic competence, migration ability and cell death resistance than reprogrammed fibroblasts

Xia, X., Li, C., Wang, Y., Deng, X., Ma, Y., Ding, L. & Zheng, J., Feb 8 2020, In : Translational Neurodegeneration. 9, 1, 6.

Research output: Contribution to journalArticle

Open Access

Reprogramming of ovarian granulosa cells by YAP1 leads to development of high-grade cancer with mesenchymal lineage and serous features

Lv, X., He, C., Huang, C., Hua, G., Chen, X., Timm, B. K., Maclin, V. M., Haggerty, A. A., Aust, S. K., Golden, D. M., Dave, B. J., Tseng, Y. A., Chen, L., Wang, H., Chen, P., Klinkebiel, D. L., Karpf, A. R., Dong, J., Drapkin, R. I., Rueda, B. R. & 2 others, Davis, J. S. & Wang, C., Jan 1 2020, (Accepted/In press) In : Science Bulletin.

Research output: Contribution to journalArticle

Rilpivirine-associated aggregation-induced emission enables cell-based nanoparticle tracking

Mukadam, I. Z., Machhi, J., Herskovitz, J., Hasan, M., Oleynikov, M. D., Blomberg, W. R., Svechkarev, D., Mohs, A. M., Zhou, Y., Dash, P., McMillan, J. E., Gorantla, S., Garrison, J., Gendelman, H. E. & Kevadiya, B. D., Feb 2020, In : Biomaterials. 231, 119669.

Research output: Contribution to journalArticle

3 Scopus citations

Sorting nexin 17 (SNX17) links endosomal sorting to Eps15 homology domain protein 1 (EHD1)-mediated fission machinery

Dhawan, K., Naslavsky, N., Caplan, S. & Hanson, P. I., Mar 20 2020, In : Journal of Biological Chemistry. 295, 12, p. 3837-3850 14 p.

Research output: Contribution to journalArticle

1 Scopus citations

Squamous trans-differentiation of pancreatic cancer cells promotes stromal inflammation

Somerville, T. D. D., Biffi, G., Daßler-Plenker, J., Hur, S. K., He, X. Y., Vance, K. E., Miyabayashi, K., Xu, Y., Maia-Silva, D., Klingbeil, O., Demerdash, O. E., Preall, J. B., Hollingsworth, M. A., Egeblad, M., Tuveson, D. A. & Vakoc, C. R., Apr 2020, In : eLife. 9, e53381.

Research output: Contribution to journalArticle

Open Access

Stromal Modulation and Treatment of Metastatic Pancreatic Cancer with Local Intraperitoneal Triple miRNA/siRNA Nanotherapy

Xie, Y., Hang, Y., Wang, Y., Sleightholm, R., Prajapati, D. R., Bader, J., Yu, A., Tang, W., Jaramillo, L., Li, J., Singh, R. K. & Oupický, D., Jan 28 2020, In : ACS Nano. 14, 1, p. 255-271 17 p.

Research output: Contribution to journalArticle

2 Scopus citations

Targeting the IκB Kinase Enhancer and Its Feedback Circuit in Pancreatic Cancer

Challa, S., Husain, K., Kim, R., Coppola, D., Batra, S. K., Cheng, J. Q. & Malafa, M. P., Feb 2020, In : Translational Oncology. 13, 2, p. 481-489 9 p.

Research output: Contribution to journalArticle

Open Access

The proteomic landscape of pancreatic ductal adenocarcinoma liver metastases identifies molecular subtypes and associations with clinical response A C

Law, H. C. H., Lagundzin, D., Clement, E. J., Qiao, F., Wagner, Z. S., Krieger, K. L., Costanzo-Garvey, D., Caffrey, T. C., Grem, J. L., DiMaio, D. J., Grandgenett, P. M., Cook, L. M., Fisher, K. W., Yu, F., Hollingsworth, M. A. & Woods, N. T., Mar 1 2020, In : Clinical Cancer Research. 26, 5, p. 1065-1076 12 p.

Research output: Contribution to journalArticle

Open Access