Research output per year
Research output per year
- 1 - 50 out of 401 results
Search results
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2025
A Phase II Trial of Geriatric Assessment-Guided Selection of Treatment Intensity in Older Adults With AML
Bhatt, V. R., Wichman, C. S., Koll, T. T., Fisher, A. L., Wildes, T. M., Haddadin, M., Berger, A. M., Armitage, J. O., Holstein, S. A., Maness, L. J. & Gundabolu, K., 2025, (Accepted/In press) In: American Journal of Hematology.Research output: Contribution to journal › Article › peer-review
Open Access -
Autophosphorylation of the Tousled-like kinases TLK1 and TLK2 regulates recruitment to damaged chromatin via PCNA interaction
West, K. L., Nguyen, T. T. N., Tengler, K. A., Kreiling, N., Raney, K. D., Ghosal, G. & Leung, J. W., Feb 28 2025, In: Nucleic acids research. 53, 4, gkae1279.Research output: Contribution to journal › Article › peer-review
Open Access -
Geranylgeranyl diphosphate synthase inhibition impairs osteoclast differentiation, morphology, and resorptive activity
Muehlebach, M. E., Haney, S. L., Chhonker, Y. S., Rashid, M., Murry, D. J., Talmon, G. & Holstein, S. A., Jan 1 2025, In: JBMR Plus. 9, 1, ziae133.Research output: Contribution to journal › Article › peer-review
Open Access -
Humanized Anti-MUC16 Antibody-Conjugated Contrast Agents for Magnetic Resonance Imaging of Pancreatic Cancer
Mathiyazhagan, J., Rajesh, C., Sagar, S., Caffrey, T. C., Huang, Y., Mohs, A. M., Swanson, B. J., Hollingsworth, M. A., Brooks, C. L. & Radhakrishnan, P., Mar 2025, In: Cancers. 17, 6, 957.Research output: Contribution to journal › Article › peer-review
Open Access -
Impact of fixed phosphorus position on activity of triazole bisphosphonates as geranylgeranyl diphosphate synthase inhibitors
Ayub Ali, M., Maalouf, M. A., Feng, D., Rashid, M., Gehrke, N. R., Chhonker, Y. S., Murry, D. J., Wiemer, D. F. & Holstein, S. A., May 1 2025, In: Bioorganic and Medicinal Chemistry. 122, 118140.Research output: Contribution to journal › Article › peer-review
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Neurotoxicity and Rare Adverse Events in BCMA-Directed CAR T Cell Therapy: A Comprehensive Analysis of Real-World FAERS Data
Ellithi, M., Elsallab, M., Lunning, M. A., Holstein, S. A., Sharma, S., Trinh, J. Q., Ma, J., Maus, M. V., Frigault, M. J. & D'Angelo, C. R., Feb 2025, In: Transplantation and Cellular Therapy. 31, 2, p. 71.e1-71.e14Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
Structural Optimization of Covalent Inhibitors for Deubiquitinase ChlaDUB1 of Chlamydia trachomatis as Antibiotic Agents
Zimmermann, T., Feng, J., Fischer, S., de Campos, L. J., Pinheiro, F. R., Sotriffer, C., Conda-Sheridan, M. & Decker, M., Mar 13 2025, In: Journal of Medicinal Chemistry. 68, 5, p. 5400-5425 26 p.Research output: Contribution to journal › Article › peer-review
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Structure-activity relationship of isoprenoid triazole bisphosphonate-based geranylgeranyl diphosphate synthase inhibitors: Effects on pharmacokinetics, biodistribution, and hepatic transporters
Haney, S. L., Chhonker, Y. S., Rashid, M., Murry, D. J. & Holstein, S. A., Mar 2025, In: Drug Metabolism and Disposition. 53, 3, 100038.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Targeted interferon therapy with modakafusp alfa for relapsed or refractory multiple myeloma
Vogl, D. T., Atrash, S., Holstein, S. A., Nadeem, O., Benson, D., Chaudry, M., Biran, N., Suryanarayan, K., Li, C., Liu, Y., Collins, S., Parot, X. & Kaufman, J. L., Feb 27 2025, In: Blood. 145, 9, p. 944-955 12 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
The role of Tyr34 in proton coupled electron transfer and product inhibition of manganese superoxide dismutase
Azadmanesh, J., Slobodnik, K., Struble, L. R., Lovelace, J. J., Cone, E. A., Dasgupta, M., Lutz, W. E., Kumar, S., Natarajan, A., Coates, L., Weiss, K. L., Myles, D. A. A., Kroll, T. & Borgstahl, G. E. O., Dec 2025, In: Nature communications. 16, 1, 1887.Research output: Contribution to journal › Article › peer-review
Open Access -
2024
Cbl and Cbl-b ubiquitin ligases are essential for intestinal epithelial stem cell maintenance
Zutshi, N., Mohapatra, B. C., Mondal, P., An, W., Goetz, B. T., Wang, S., Li, S., Storck, M. D., Mercer, D. F., Black, A. R., Thayer, S. P., Black, J. D., Lin, C., Band, V. & Band, H., Jun 21 2024, In: iScience. 27, 6, 109912.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
DNA polymerase ε and δ variants drive mutagenesis in polypurine tracts in human tumors
Ostroverkhova, D., Tyryshkin, K., Beach, A. K., Moore, E. A., Masoudi-Sobhanzadeh, Y., Barbari, S. R., Rogozin, I. B., Shaitan, K. V., Panchenko, A. R. & Shcherbakova, P. V., Jan 23 2024, In: Cell Reports. 43, 1, 113655.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Evaluating the antimicrobial and anti-biofilm activity of three synthetic antimicrobial Citropin analogs and their ability to fight against Staphylococcus aureus and Staph ylococcus pseudinter medius
Salvado, M. G., André, L. S. P., Pereira, R. F. A., Pinheiro, F. R., das Chagas Barbosa, B., Scaffo, J. C., Pereira, A. J., Arakaki, D. G., Xing, H., de Oliveira, K. M. P., de Andrade dos Santos, J. V., Sachs, D., Aguiar-Alves, F., Conda-Sheridan, M. & Penna, B., Jun 2024, In: Journal of Applied Microbiology. 135, 6, lxae127.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
GD2 and its biosynthetic enzyme GD3 synthase promote tumorigenesis in prostate cancer by regulating cancer stem cell behavior
Bhat, A. M., Mohapatra, B. C., Luan, H., Mushtaq, I., Chakraborty, S., Kumar, S., Wu, W., Nolan, B., Dutta, S., Storck, M. D., Schott, M., Meza, J. L., Lele, S. M., Lin, M. F., Cook, L. M., Corey, E., Morrissey, C., Coulter, D. W., Rowley, M. J. & Natarajan, A. & 3 others, , Dec 2024, In: Scientific reports. 14, 1, 13523.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Immunogenic Cell Death Traits Emitted from Chronic Lymphocytic Leukemia Cells Following Treatment with a Novel Anti-Cancer Agent, SpiD3
Schmitz, E., Ridout, A., Smith, A. L., Eiken, A. P., Skupa, S. A., Drengler, E. M., Singh, S., Rana, S., Natarajan, A. & El-Gamal, D., Dec 2024, In: Biomedicines. 12, 12, 2857.Research output: Contribution to journal › Article › peer-review
Open Access -
Investigation of the activity of a novel tropolone in osteosarcoma
Haney, S. L., Feng, D., Kollala, S. S., Chhonker, Y. S., Varney, M. L., Williams, J. T., Ford, J. B., Murry, D. J. & Holstein, S. A., Feb 2024, In: Drug Development Research. 85, 1, e22129.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Longitudinal changes in cognitive and physical function and health-related quality of life in older adults with acute myeloid leukemia
Bhatt, V. R., Wichman, C., Koll, T. T., Fisher, A. L., Wildes, T. M., Berger, A., Armitage, J. O., Holstein, S. A., Maness, L. J. & Gundabolu, K., Jan 2024, In: Journal of Geriatric Oncology. 15, 1, 101676.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Machine learning assisted identification of antibiotic-resistant Staphylococcus aureus strains using a paper-based ratiometric sensor array
Laliwala, A., Gupta, R., Svechkarev, D., Bayles, K. W., Sadykov, M. R. & Mohs, A. M., Nov 2024, In: Microchemical Journal. 206, 111395.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
MUC16 Retention after Neoadjuvant Chemotherapy in Pancreatic Ductal Adenocarcinoma
Muilenburg, K. M., Ehrhorn, E. G., Olson, M. T., Isder, C. C., Klute, K. A., Talmon, G. A., Carlson, M. A., Ly, Q. P. & Mohs, A. M., Oct 2024, In: Cancers. 16, 20, 3439.Research output: Contribution to journal › Article › peer-review
Open Access -
Novel Spirocyclic Dimer, SpiD3, Targets Chronic Lymphocytic Leukemia Survival Pathways with Potent Preclinical Effects
Eiken, A. P., Smith, A. L., Skupa, S. A., Schmitz, E., Rana, S., Singh, S., Kumar, S., Mallareddy, J. R., de Cubas, A. A., Krishna, A., Kalluchi, A., Rowley, M. J., D’Angelo, C. R., Lunning, M. A., Bociek, R. G., Vose, J. M., Natarajan, A. & El-Gamal, D., May 1 2024, In: Cancer Research Communications. 4, 5, p. 1328-1343 16 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Optimizing the performance of silica nanoparticles functionalized with a near-infrared fluorescent dye for bioimaging applications
Ehrhorn, E. G., Lovell, P., Svechkarev, D., Romanova, S. & Mohs, A. M., Jul 22 2024, In: Nanotechnology. 35, 30, 305605.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
Piplartine attenuates aminoglycoside-induced TRPV1 activity and protects from hearing loss in mice
Zallocchi, M., Vijayakumar, S., Fleegel, J., Batalkina, L., Brunette, K. E., Shukal, D., Chen, Z., Devuyst, O., Liu, H., He, D. Z. Z., Imami, A. S., Hamoud, A. R. A., McCullumsmith, R., Conda-Sheridan, M., De Campos, L. J. & Zuo, J., 2024, In: Science translational medicine. 16, 759, eadn2140.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Post hoc analysis of daratumumab plus lenalidomide, bortezomib and dexamethasone in Black patients from final data of the GRIFFIN study
Nooka, A. K., Kaufman, J. L., Rodriguez, C., Jakubowiak, A., Efebera, Y., Reeves, B., Wildes, T. M., Holstein, S. A., Anderson, L. D., Badros, A., Shune, L., Chari, A., Pei, H., Cortoos, A., Patel, S., Lin, T. S., Voorhees, P. M., Usmani, S. Z. & Richardson, P. G., Jun 2024, In: British Journal of Haematology. 204, 6, p. 2227-2232 6 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Revealing the atomic and electronic mechanism of human manganese superoxide dismutase product inhibition
Azadmanesh, J., Slobodnik, K., Struble, L. R., Lutz, W. E., Coates, L., Weiss, K. L., Myles, D. A. A., Kroll, T. & Borgstahl, G. E. O., Dec 2024, In: Nature communications. 15, 1, 5973.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
Structural Basis for Multivalent MUC16 Recognition and Robust Anti-Pancreatic Cancer Activity of Humanized Antibody AR9.6
Aguilar, E. N., Sagar, S., Murray, B. R., Rajesh, C., Lei, E. K., Michaud, S. A., Goodlett, D. R., Caffrey, T. C., Grandgenett, P. M., Swanson, B., Brooks, T. M., Black, A. R., van Faassen, H., Hussack, G., Henry, K. A., Hollingsworth, M. A., Brooks, C. L. & Radhakrishnan, P., Jun 1 2024, In: Molecular cancer therapeutics. 23, 6, p. 836-853 18 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Structural Basis for the Interaction Between Yeast Chromatin Assembly Factor 1 and Proliferating Cell Nuclear Antigen: Binding of CAF-1 PIP motif by PCNA
Orndorff, K. S., Veltri, E. J., Hoitsma, N. M., Williams, I. L., Hall, I., Jaworski, G. E., Majeres, G. E., Kallepalli, S., Vito, A. F., Struble, L. R., Borgstahl, G. E. O. & Dieckman, L. M., Aug 15 2024, In: Journal of Molecular Biology. 436, 16, 168695.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Structure-Activity Relationship Study to Develop Peptide Amphiphiles as Species-Specific Antimicrobials
Pereira, A. J., Xing, H., de Campos, L. J., Seleem, M. A., de Oliveira, K. M. P., Obaro, S. K. & Conda-Sheridan, M., Mar 12 2024, In: Chemistry - A European Journal. 30, 15, e202303986.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Structure-Based Design and Synthesis of Covalent Inhibitors for Deubiquitinase and Acetyltransferase ChlaDUB1 of Chlamydia trachomatis
Zimmermann, T., Feng, J., de Campos, L. J., Knight, L. A., Schlötzer, J., Ramirez, Y. A., Schwickert, K., Zehe, M., Adler, T. B., Schirmeister, T., Kisker, C., Sotriffer, C., Conda-Sheridan, M. & Decker, M., Jul 11 2024, In: Journal of Medicinal Chemistry. 67, 13, p. 10710-10742 33 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
Targeting Human Pancreatic Cancer with a Fluorophore-Conjugated Mucin 4 (MUC4) Antibody: Initial Characterization in Orthotopic Cell Line Mouse Models
Jaiswal, S., Cox, K. E., Amirfakhri, S., Din Parast Saleh, A., Kobayashi, K., Lwin, T. M., Talib, S., Aithal, A., Mallya, K., Jain, M., Mohs, A. M., Hoffman, R. M., Batra, S. K. & Bouvet, M., Oct 2024, In: Journal of Clinical Medicine. 13, 20, 6211.Research output: Contribution to journal › Article › peer-review
Open Access -
The Novel Anti-Cancer Agent, SpiD3, Is Cytotoxic in CLL Cells Resistant to Ibrutinib or Venetoclax
Eiken, A. P., Schmitz, E., Drengler, E. M., Smith, A. L., Skupa, S. A., Mohan, K., Rana, S., Singh, S., Mallareddy, J. R., Mathew, G., Natarajan, A. & El-Gamal, D., Sep 2024, In: Hemato. 5, 3, p. 321-339 19 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Ubiquitin E3 Ligase FBXO9 Regulates Pluripotency by Targeting DPPA5 for Ubiquitylation and Degradation
Swenson, S. A., Dobish, K. K., Peters, H. C., Bea Winship, C., Hynes-Smith, R. W., Caplan, M., Wittorf, K. J., Ghosal, G. & Buckley, S. M., Apr 2024, In: STEM CELLS. 42, 4, p. 317-328 12 p.Research output: Contribution to journal › Article › peer-review
Open Access -
α-Amino bisphosphonate triazoles serve as GGDPS inhibitors
Gehrke, N. R., Feng, D., Ayub Ali, M., Maalouf, M. A., Holstein, S. A. & Wiemer, D. F., Apr 1 2024, In: Bioorganic and Medicinal Chemistry Letters. 102, 129659.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
2023
A Ferritin Nanoparticle-Based Zika Virus Vaccine Candidate Induces Robust Humoral and Cellular Immune Responses and Protects Mice from Lethal Virus Challenge
Pattnaik, A., Sahoo, B. R., Struble, L. R., Borgstahl, G. E. O., Zhou, Y., Franco, R., Barletta, R. G., Osorio, F. A., Petro, T. M. & Pattnaik, A. K., Apr 2023, In: Vaccines. 11, 4, 821.Research output: Contribution to journal › Article › peer-review
Open Access17 Scopus citations -
A Simple and Sensitive LC-MS/MS for Quantitation of ICG in Rat Plasma: Application to a Pre-Clinical Pharmacokinetic Study
Chhonker, Y. S., Wojtynek, N. E., Agrawal, P., Mohs, A. M. & Murry, D. J., Feb 2023, In: Separations. 10, 2, 66.Research output: Contribution to journal › Article › peer-review
Open Access -
Cdk5 mediates rotational force-induced brain injury
Umfress, A., Chakraborti, A., Priya Sudarsana Devi, S., Adams, R., Epstein, D., Massicano, A., Sorace, A., Singh, S., Iqbal Hossian, M., Andrabi, S. A., Crossman, D. K., Kumar, N., Shahid Mukhtar, M., Luo, H., Simpson, C., Abell, K., Stokes, M., Wiederhold, T., Rosen, C. & Lu, H. & 2 others, , Dec 2023, In: Scientific reports. 13, 1, 3394.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Ciltacabtagene autoleucel for the treatment of multiple myeloma
Holstein, S. A., Jan 2023, In: Drugs of Today. 59, 1, p. 1-16 16 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
Combined inhibition of aurora kinases and Bcl-xL induces apoptosis through select BH3-only proteins
Li, J., Chen, C. H., O'Neill, K. L., Fousek-Schuller, V. J., Black, A. R., Black, J. D., Zhang, J. & Luo, X., Feb 2023, In: Journal of Biological Chemistry. 299, 2, 102875.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Conformal Electrodeposition of Antimicrobial Hydrogels Formed by Self-Assembled Peptide Amphiphiles
Zaldivar, G., Feng, J., Lizarraga, L., Yu, Y., de Campos, L., de Oliveira, K. M. P., Piepenbrink, K. H., Conda-Sheridan, M. & Tagliazucchi, M., Jun 6 2023, In: Advanced Materials Interfaces. 10, 16, 2300046.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Crosstalk between protein kinase C α and transforming growth factor β signaling mediated by Runx2 in intestinal epithelial cells
Li, X., Kaur, N., Albahrani, M., Karpf, A. R., Black, A. R. & Black, J. D., Apr 2023, In: Journal of Biological Chemistry. 299, 4, 103017.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Defining a cohort of anemia-activated cis elements reveals a mechanism promoting erythroid precursor function
Zhou, Y., Dogiparthi, V. R., Ray, S., Schaefer, M. A., Harris, H. L., Rowley, M. J. & Hewitt, K. J., Oct 24 2023, In: Blood Advances. 7, 20, p. 6325-6338 14 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
De novo design of a stapled peptide targeting SARS-CoV-2 spike protein receptor-binding domain
Thakkar, R., Agarwal, D. K., Ranaweera, C. B., Ishiguro, S., Conda-Sheridan, M., Gaudreault, N. N., Richt, J. A., Tamura, M. & Comer, J., Jul 31 2023, In: RSC Medicinal Chemistry. 14, 9, p. 1722-1733 12 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Design, Biological Evaluation, and Computer-Aided Analysis of Dihydrothiazepines as Selective Antichlamydial Agents
de Campos, L. J., Seleem, M. A., Feng, J., Pires de Oliveira, K. M., de Andrade dos Santos, J. V., Hayer, S., Clayton, J. B., Kathi, S., Fisher, D. J., Ouellette, S. P. & Conda-Sheridan, M., Feb 9 2023, In: Journal of Medicinal Chemistry. 66, 3, p. 2116-2142 27 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Design, synthesis, and evaluation of a mitoxantrone probe (MXP) for biological studies
Wallin, S., Singh, S., Borgstahl, G. E. O. & Natarajan, A., Oct 1 2023, In: Bioorganic and Medicinal Chemistry Letters. 94, 129465.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Designing peptide amphiphiles as novel antibacterials and antibiotic adjuvants against gram-negative bacteria
Xing, H., Loya-Perez, V., Franzen, J., Denton, P. W., Conda-Sheridan, M. & Rodrigues de Almeida, N., Oct 30 2023, In: Bioorganic and Medicinal Chemistry. 94, 117481.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
Discovery, synthesis and biological evaluation of a series of N-(phenylcarbamothioyl)-2-napthamides as inhibitors of Claudin-1
Mashinson, V., Webster, T. M., Vadukoot, A. K., Tolentino, K. T., Simeon, P., Fatima, I., Dhawan, P. & Hopkins, C. R., Sep 7 2023, In: Bioorganic and Medicinal Chemistry. 92, 117416.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
EHD1-dependent traffic of IGF-1 receptor to the cell surface is essential for Ewing sarcoma tumorigenesis and metastasis
Chakraborty, S., Bhat, A. M., Mushtaq, I., Luan, H., Kalluchi, A., Mirza, S., Storck, M. D., Chaturvedi, N., Lopez-Guerrero, J. A., Llombart-Bosch, A., Machado, I., Scotlandi, K., Meza, J. L., Ghosal, G., Coulter, D. W., Jordan Rowley, M., Band, V., Mohapatra, B. C. & Band, H., Dec 2023, In: Communications biology. 6, 1, 758.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Ethical Challenges with Multiple Myeloma BCMA Chimeric Antigen Receptor T Cell Slot Allocation: A Multi-Institution Experience
Kourelis, T., Bansal, R., Berdeja, J., Siegel, D., Patel, K., Mailankody, S., Htut, M., Shah, N., Wong, S. W., Sidana, S., Cowan, A. J., Alsina, M., Cohen, A., Holstein, S. A., Bergsagel, L., Ailawadhi, S., Raje, N., Dhakal, B., Rossi, A. & Lin, Y., Apr 2023, In: Transplantation and Cellular Therapy. 29, 4, p. 255-258 4 p.Research output: Contribution to journal › Article › peer-review
Open Access40 Scopus citations -
Evaluation of geranylgeranyl diphosphate synthase inhibition as a novel strategy for the treatment of osteosarcoma and Ewing sarcoma
Haney, S. L., Feng, D., Chhonker, Y. S., Varney, M. L., Williams, J. T., Smith, L. M., Ford, J. B., Murry, D. J. & Holstein, S. A., Feb 2023, In: Drug Development Research. 84, 1, p. 62-74 13 p.Research output: Contribution to journal › Article › peer-review
9 Scopus citations -
Evolution of the triplet BRCT domain
Mota, M. B. S., Woods, N. T., Carvalho, M. A., Monteiro, A. N. A. & Mesquita, R. D., Sep 2023, In: DNA Repair. 129, 103532.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
FBXO21 mediated degradation of p85α regulates proliferation and survival of acute myeloid leukemia
Dobish, K. K., Wittorf, K. J., Swenson, S. A., Bean, D. C., Gavile, C. M., Woods, N. T., Ghosal, G., Hyde, R. K. & Buckley, S. M., Nov 2023, In: Leukemia. 37, 11, p. 2197-2208 12 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations