Computational Chemistry & Innovative Therapeutics

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  Maximizing cancer synthetic lethality using dual PI-3K/PARP inhibitors

  Durden, D. L.

  Project: Research project

• A Phase I study of a dual PI3K/BRD4 inhibitor, SF1126 in the treatment of hepatocellular carcinoma | IDE: 74,551

  Durden, D. L.

  Project: Research project

• Maximal MYC control using dual PI-3K/BRD4 (kinase/epigenetic) inhibitors

  Durden, D. L.

  Project: Research project

• BIOLOGY AND THERAPY OF HIGH-RISK NEUROBLASTOMA

  Durden, D. L.

  Project: Research project

• Role of PTEN and PI-3 kinase in medulloblastomagenesis

  Durden, D. L.

  Project: Research project

• Role of Syk and Rac2 in regulation of HIF1alpha and neovascularization.

  Durden, D. L.

  Project: Research project

• Dual PI3K/BRD4 inhibitory chemotype for maximum inhibition of Myc and cancer

  Durden, D. L.

  Project: Research project

• Role of Rac2 in Development and Function of Blood Cells

  Durden, D. L.

  Project: Research project

• PTEN/AKTp53 signaling axis in tumor induced angiogenesis

  Durden, D. L.

  Project: Research project

• Phase 2 Study of Poly-ICLC in the Treatment of Pediatric Low Grade Gliomas

  Durden, D. L.

  Project: Research project

• PHASE II STUDY FOR TREATMENT OF PEDIATRIC BRAIN TUMORS

  Durden, D. L.

  Project: Research project