Research output per year
Research output per year
- 31 results
Search results
-
2019
Combinatorial Approach to Improve Cancer Immunotherapy: Rational Drug Design Strategy to Simultaneously Hit Multiple Targets to Kill Tumor Cells and to Activate the Immune System
Joshi, S. & Durden, D. L., 2019, In: Journal of Oncology. 2019, 5245034.Research output: Contribution to journal › Review article › peer-review
Open Access59 Scopus citations -
Erratum: Vascular permeability and remodelling coincide with inflammatory and reparative processes after joint bleeding in factor VIII-deficient mice (Thrombosis and Haemostasis (2018) 118:6 DOI: 10.1055/s-0038-1641755)
Cooke, E. J., Zhou, J. Y., Wyseure, T., Joshi, S., Bhat, V., Durden, D. L., Mosnier, L. O. & Von Drygalski, A., 2019, In: Thrombosis and Haemostasis. 119, 9, p. 1546 1 p.Research output: Contribution to journal › Comment/debate › peer-review
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SF2523: Dual PI3K/BRD4 inhibitor blocks tumor immunosuppression and promotes adaptive immune responses in cancer
Joshi, S., Singh, A. R., Liu, K. X., Pham, T. V., Zulcic, M., Skola, D., Chun, H. B., Glass, C. K., Morales, G. A., Garlich, J. R. & Durden, D. L., 2019, In: Molecular cancer therapeutics. 18, 6, p. 1036-1044 9 p.Research output: Contribution to journal › Article › peer-review
Open Access21 Scopus citations -
2017
The differential ability of asparagine and glutamine in promoting the closed/active enzyme conformation rationalizes the Wolinella succinogenes L-asparaginase substrate specificity
Nguyen, H. A., Durden, D. L. & Lavie, A., Jan 31 2017, In: Scientific reports. 7, 41643.Research output: Contribution to journal › Article › peer-review
18 Scopus citations -
2015
Vascular remodeling underlies rebleeding in hemophilic arthropathy
Bhat, V., Olmer, M., Joshi, S., Durden, D. L., Cramer, T. J., Barnes, R. F. W., Ball, S. T., Hughes, T. H., Silva, M., Luck, J. V., Moore, R. E., Mosnier, L. O. & von Drygalski, A., Nov 2015, In: American Journal of Hematology. 90, 11, p. 1027-1035 9 p.Research output: Contribution to journal › Article › peer-review
55 Scopus citations -
2014
Rac2 controls tumor growth, metastasis and M1-M2 macrophage differentiation in vivo
Joshi, S., Singh, A. R., Zulcic, M., Bao, L., Messer, K., Ideker, T., Dutkowski, J. & Durden, D. L., Apr 25 2014, In: PloS one. 9, 4, e95893.Research output: Contribution to journal › Article › peer-review
74 Scopus citations -
2013
Synthesis and cancer stem cell-based activity of substituted 5-morpholino-7H-thieno[3,2-b]pyran-7-ones designed as next generation PI3K inhibitors
Morales, G. A., Garlich, J. R., Su, J., Peng, X., Newblom, J., Weber, K. & Durden, D. L., Mar 14 2013, In: Journal of Medicinal Chemistry. 56, 5, p. 1922-1939 18 p.Research output: Contribution to journal › Article › peer-review
38 Scopus citations -
2012
SF1126, a Pan-PI3K inhibitor has potent pre-clinical activity in aggressive B-cell non-Hodgkin lymphomas by inducing cell cycle arrest and apoptosis
Qi, W., Stejskal, A., Morales, C., Cooke, L. S., Garlich, J. R., Durden, D. & Mahadevan, D., 2012, In: Journal of Cancer Science and Therapy. 4, 7, p. 207-213 7 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
2010
Heterozygosity for Ptenpromotes Tumorigenesis in a Mouse Model of Medulloblastoma
Castellino, R. C., Barwick, B. G., Schniederjan, M., Buss, M. C., Becher, O., Hambardzumyan, D., Macdonald, T. J., Brat, D. J. & Durden, D. L., 2010, In: PloS one. 5, 5, e10849.Research output: Contribution to journal › Article › peer-review
38 Scopus citations -
2009
Erratum to "Expression of RAC2 in endothelial cells is required for the postnatal neovascular response" [Exp. Cell Res. 315 (2009) 248-263] (DOI:10.1016/j.yexcr.2008.10.003)
De, P., Peng, Q., Traktuev, D. O., Li, W., Yoder, M. C., March, K. L. & Durden, D. L., Oct 1 2009, In: Experimental Cell Research. 315, 16, p. 2869 1 p.Research output: Contribution to journal › Comment/debate › peer-review
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Expression of RAC2 in endothelial cells is required for the postnatal neovascular response
De, P., Peng, Q., Traktuevc, D. O., Li, W., Yoder, M. C., March, K. L. & Durden, D. L., Jan 15 2009, In: Experimental Cell Research. 315, 2, p. 248-263 16 p.Research output: Contribution to journal › Article › peer-review
16 Scopus citations -
2006
'Pseudopalisading' necrosis in glioblastoma: A familiar morphologic feature that links vascular pathology, hypoxia, and angiogenesis
Rong, Y., Durden, D. L., Van Meir, E. G. & Brat, D. J., Jun 2006, In: Journal of Neuropathology and Experimental Neurology. 65, 6, p. 529-539 11 p.Research output: Contribution to journal › Review article › peer-review
374 Scopus citations -
2005
CSK negatively regulates nerve growth factor induced neural differentiation and augments AKT kinase activity
Dey, N., Howell, B. W., De, P. K. & Durden, D. L., Jul 1 2005, In: Experimental Cell Research. 307, 1, p. 1-14 14 p.Research output: Contribution to journal › Article › peer-review
31 Scopus citations -
Cytokine expression and signaling in brain tumors
Dey, N., Durden, D. L. & Van Meir, E. G., Jan 1 2005, Cytokines and the CNS. CRC Press, p. 194-242 49 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
1 Scopus citations -
2003
Rac2 Specificity in Macrophage Integrin Signaling: Potential role for Syk kinase
Pradip, D., Peng, X. & Durden, D. L., Oct 24 2003, In: Journal of Biological Chemistry. 278, 43, p. 41661-41669 9 p.Research output: Contribution to journal › Article › peer-review
41 Scopus citations -
2002
Ceramide signaling in fenretinide-induced endothelial cell apoptosis
Erdreich-Epstein, A., Tran, L. B., Bowman, N. N., Wang, H., Cabot, M. C., Durden, D. L., Vlckova, J., Reynolds, C. P., Stins, M. F., Groshen, S. & Millard, M., Dec 20 2002, In: Journal of Biological Chemistry. 277, 51, p. 49531-49537 7 p.Research output: Contribution to journal › Article › peer-review
74 Scopus citations -
SHP-1 regulates Fcγ receptor-mediated phagocytosis and the activation of RAC
Kant, A. M., De, P., Peng, X., Yi, T., Rawlings, D. J., Kim, J. S. & Durden, D. L., Sep 1 2002, In: Blood. 100, 5, p. 1852-1859 8 p.Research output: Contribution to journal › Article › peer-review
59 Scopus citations -
2001
Plasminogen activator inhibitor-1 promotes angiogenesis by stimulating endothelial cell migration toward fibronectin
Isogai, C., Laug, W. E., Shimada, H., Declerck, P. J., Stins, M. F., Durden, D. L., Erdreich-Epstein, A. & DeClerck, Y. A., Jul 15 2001, In: Cancer Research. 61, 14, p. 5587-5594 8 p.Research output: Contribution to journal › Article › peer-review
138 Scopus citations -
Treatment of collagen induced arthritis in DBA/1 mice with L-asparaginase
Reiff, A., Zastrow, M., Sun, B. C., Takei, S., Mitsuhada, H., Bernstein, B. & Durden, D. L., 2001, In: Clinical and experimental rheumatology. 19, 6, p. 639-646 8 p.Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
1999
High affinity IgG receptor activation of Src family kinases is required for modulation of the Shc-Grb2-Sos complex and the downstream activation of the nicotinamide adenine dinucleotide phosphate (reduced) oxidase
Park, R. K., Erdreich-Epstein, A., Liu, M., Izadi, K. D. & Durden, D. L., Dec 1 1999, In: Journal of Immunology. 163, 11, p. 6023-6034 12 p.Research output: Contribution to journal › Article › peer-review
6 Scopus citations -
1998
CBL-GRB2 interaction in myeloid immunoreceptor tyrosine activation motif signaling
Park, R. K., Kyono, W. T., Liu, Y. & Durden, D. L., May 15 1998, In: Journal of Immunology. 160, 10, p. 5018-5027 10 p.Research output: Contribution to journal › Article › peer-review
33 Scopus citations -
Differential interaction of Crkl with Cbl or C3G, Hef-1, and γ subunit immunoreceptor tyrosine-based activation motif in signaling of myeloid high affinity Fc receptor for IgG (FcγRI)
Kyono, W. T., De Jong, R., Park, R. K., Liu, Y., Heisterkamp, N., Groffen, J. & Durden, D. L., Nov 15 1998, In: Journal of Immunology. 161, 10, p. 5555-5563 9 p.Research output: Contribution to journal › Article › peer-review
19 Scopus citations -
1995
The FcγRI receptor signals through the activation of hck and MAP kinase
Durden, D. L., Hwang Min Kim, M. K., Calore, B. & Liu, Y., 1995, In: Journal of Immunology. 154, 8, p. 4039-4047 9 p.Research output: Contribution to journal › Article › peer-review
89 Scopus citations -
The FcγRI receptor signals through the activation of hck and MAP kinase
Durden, D. L., Kim, H. M., Calore, B. & Liu, Y., 1995, In: Journal of Immunology. 154, 8, p. 4048-4054 7 p.Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
1994
Protein-tyrosine kinase p72(syk) in FcγRI receptor signaling
Durden, D. L. & Yen bou Liu, B. L., 1994, In: Blood. 84, 7, p. 2102-2108 7 p.Research output: Contribution to journal › Article › peer-review
Open Access55 Scopus citations -
1982
Alteration in spleen lymphoid populations associated with specific amino acid depletion during l-asparaginase treatment
Distasio, J. A., Durden, D. L., Paul, R. D. & Nadji, M., Jan 1 1982, In: Cancer Research. 42, 1, p. 252-258 7 p.Research output: Contribution to journal › Article › peer-review
14 Scopus citations -
Glutaminase‐free asparaginase from vibrio succinogenes: An antilymphoma enzyme lacking hepatotoxicity
Distasio, J. A., Salazar, A. M., Nadji, M. & Durden, D. L., Sep 15 1982, In: International Journal of Cancer. 30, 3, p. 343-347 5 p.Research output: Contribution to journal › Article › peer-review
61 Scopus citations -
Vibrio succinogenes asparaginase: An antilymphoma agent lacking hepatotoxicity
Durden, D. L., Salazar, A. M., Nadji, M. & Distasio, J. A., 1982, In: Proceedings of the American Association for Cancer Research. Vol. 23, p. No. 805Research output: Contribution to journal › Article › peer-review
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1981
Characterization of the effects of asparaginase from escherichia coli and a glutaminase‐free asparaginase from vibrio succinogenes on specific cell‐mediated cytotoxicity
Durden, D. L. & Distasio, J. A., Jan 15 1981, In: International Journal of Cancer. 27, 1, p. 59-65 7 p.Research output: Contribution to journal › Article › peer-review
23 Scopus citations -
1980
Comparison of the immunosuppressive effects of asparaginases from escherichia coli and vibrio succinogenes
Durden, D. L. & Distasic, J. A., Apr 1 1980, In: Cancer Research. 40, 4, p. 1125-1129 5 p.Research output: Contribution to journal › Article › peer-review
33 Scopus citations -
1979
Mouse mammary tumor virus (MMTV) antigen(s) are present on B lymphocytes of BALB/c mice
Charyulu, V., Sigel, M. M., Durden, D. L. & Lopez, D. M., Dec 15 1979, In: International Journal of Cancer. 24, 6, p. 813-818 6 p.Research output: Contribution to journal › Article › peer-review
14 Scopus citations