Eppley Institute for Cancer Research

Research Output

2020

A comparative analysis of survival and funding discrepancies in cancers with high mortality

Hall, B. R., Cannon, A., Atri, P., Wichman, C. S., Smith, L. M., Kumar, S., Batra, S. K., Wang, H., Ganti, A. K., Sasson, A. R. & Are, C., Feb 1 2020, In : Annals of surgery. 271, 2, p. 296-302 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

Advances in cancer cachexia: Intersection between affected organs, mediators, and pharmacological interventions

Siddiqui, J. A., Pothuraju, R., Jain, M., Batra, S. K. & Nasser, M. W., Apr 2020, In : Biochimica et Biophysica Acta - Reviews on Cancer. 1873, 2, 188359.

Research output: Contribution to journalReview article

AFM Probing of Amyloid-Beta 42 Dimers and Trimers

Maity, S. & Lyubchenko, Y. L., Apr 24 2020, In : Frontiers in Molecular Biosciences. 7, 69.

Research output: Contribution to journalArticle

Open Access

A Novel Combination Approach Targeting an Enhanced Protein Synthesis Pathway in MYC-driven (Group 3) Medulloblastoma

Chaturvedi, N. K., Kling, M. J., Griggs, C. N., Kesherwani, V., Shukla, M., McIntyre, E. M., Ray, S., Liu, Y., McGuire, T. R., Sharp, J. G., Band, H., Joshi, S. S. & Coulter, D. W., Jun 1 2020, In : Molecular cancer therapeutics. 19, 6, p. 1351-1362 12 p.

Research output: Contribution to journalArticle

A novel pregnene analogs: synthesis, cytotoxicity on prostate cancer of PC-3 and LNCPa-AI cells and in silico molecular docking study

Abdul-Rida, N. A., Farhan, A. M., Al-Masoudi, N. A., Saeed, B. A., Miller, D. & Lin, M. F., 2020, (Accepted/In press) In : Molecular Diversity.

Research output: Contribution to journalArticle

A phase I study of weekly doxorubicin and oral topotecan for patients with relapsed or refractory small cell lung cancer (SCLC): A Fred and Pamela Buffet Cancer Center Clinical Trials Network study

Ernani, V., Jahan, R., Smith, L. M., Marr, A. S., Kimbrough, S. E., Kos, M. E., Tijerina, J., Pivovar, S., Lakshmanan, I., Ketcham, M., Rauth, S., Mallya, K., Nasser, M. W., Jain, M., Kessinger, A., Batra, S. K. & Ganti, A. K., 2020, In : Cancer Treatment and Research Communications. 22, 100162.

Research output: Contribution to journalArticle

Open Access

ApoE mimetic peptide targeted nanoparticles carrying a BRD4 inhibitor for treating Medulloblastoma in mice

Wang, Q., Kumar, V., Lin, F., Sethi, B., Coulter, D. W., McGuire, T. R. & Mahato, R. I., Jul 10 2020, In : Journal of Controlled Release. 323, p. 463-474 12 p.

Research output: Contribution to journalArticle

Association of SOD3 promoter DNA methylation with its down-regulation in breast carcinomas

Griess, B., Klinkebiel, D., Kueh, A., Desler, M., Cowan, K., Fitzgerald, M. & Teoh-Fitzgerald, M., 2020, (Accepted/In press) In : Epigenetics.

Research output: Contribution to journalArticle

A TFAP2C gene signature is predictive of outcome in HER2-positive breast cancer

Wu, V. T., Kiriazov, B., Koch, K. E., Gu, V. W., Beck, A. C., Borcherding, N., Li, T., Addo, P., Wehrspan, Z. J., Zhang, W., Braun, T. A., Brown, B. J., Band, V., Band, H., Kulak, M. V. & Weigel, R. J., 2020, In : Molecular Cancer Research. 18, 1, p. 46-56 11 p.

Research output: Contribution to journalArticle

Atomic force microscopy-based characterization of the interaction of PriA helicase with stalledDNA replication forks

Wang, Y., Sun, Z., Bianco, P. R. & Lyubchenko, Y. L., May 1 2020, In : Journal of Biological Chemistry. 295, 18, p. 6043-6052 10 p.

Research output: Contribution to journalArticle

Autologous stem-cell transplantation for myeloma: Here to stay?

Holstein, S. A., Feb 1 2020, In : JCO Oncology Practice. 16, 2, p. 67-68 2 p.

Research output: Contribution to journalComment/debate

Cardiovascular risks and toxicity - The Achilles heel of androgen deprivation therapy in prostate cancer patients

Muniyan, S., Xi, L., Datta, K., Das, A., Teply, B. A., Batra, S. K. & Kukreja, R. C., Aug 2020, In : Biochimica et Biophysica Acta - Reviews on Cancer. 1874, 1, 188383.

Research output: Contribution to journalReview article

CAR T-Cell Therapy in Hematologic Malignancies: A Voyage in Progress

Holstein, S. A. & Lunning, M. A., Jan 1 2020, In : Clinical Pharmacology and Therapeutics. 107, 1, p. 112-122 11 p.

Research output: Contribution to journalReview article

1 Scopus citations

Characteristic fragment ions associated with dansyl cadaverine and biotin cadaverine adducts on glutamine

Biberoglu, K., Schopfer, L. M., Tacal, O. & Lockridge, O., Jul 1 2020, In : Analytical Biochemistry. 600, 113718.

Research output: Contribution to journalArticle

Open Access

Characterizing pathological imperfections in macromolecular crystals: lattice disorders and modulations

Lovelace, J. J. & Borgstahl, G. E. O., Jan 2 2020, In : Crystallography Reviews. 26, 1, p. 3-50 48 p.

Research output: Contribution to journalReview article

Chlorpyrifos oxon-induced isopeptide bond formation in human butyrylcholinesterase

Biberoglu, K., Tacal, O., Schopfer, L. M. & Lockridge, O., Jan 25 2020, In : Molecules. 25, 3, 533.

Research output: Contribution to journalArticle

Open Access

Clinical evaluation

Armitage, J. O. & Friedberg, J. W., 2020, Hematologic Malignancies. Springer, p. 99-111 13 p. (Hematologic Malignancies).

Research output: Chapter in Book/Report/Conference proceedingChapter

Comparative phenotypes of peripheral blood and spleen cells from cancer patients

Cole, K. E., Ly, Q. P., Hollingsworth, M. A., Cox, J. L., Stromnes, I. M., Padussis, J. C., Foster, J. M., Vargas, L. M. & Talmadge, J. E., Aug 2020, In : International Immunopharmacology. 85, 106655.

Research output: Contribution to journalArticle

CXCR2 signaling promotes secretory cancer-associated fibroblasts in pancreatic ductal adenocarcinoma

Awaji, M., Saxena, S., Wu, L., Prajapati, D. R., Purohit, A., Varney, M. L., Kumar, S., Rachagani, S., Ly, Q. P., Jain, M., Batra, S. K. & Singh, R. K., Jul 1 2020, In : FASEB Journal. 34, 7, p. 9405-9418 14 p.

Research output: Contribution to journalArticle

Cyclin-dependent kinase 1-mediated phosphorylation of protein kinase N1 promotes anchorage-independent growth and migration

Zeng, R., Wang, Z., Li, X., Chen, Y., Yang, S. & Dong, J., May 2020, In : Cellular Signalling. 69, 109546.

Research output: Contribution to journalArticle

Developments in continuous therapy and maintenance treatment approaches for patients with newly diagnosed multiple myeloma

Dimopoulos, M. A., Jakubowiak, A. J., McCarthy, P. L., Orlowski, R. Z., Attal, M., Bladé, J., Goldschmidt, H., Weisel, K. C., Ramasamy, K., Zweegman, S., Spencer, A., Huang, J. S. Y., Lu, J., Sunami, K., Iida, S., Chng, W. J., Holstein, S. A., Rocci, A., Skacel, T., Labotka, R. & 2 others, Palumbo, A. & Anderson, K. C., Feb 1 2020, In : Blood Cancer Journal. 10, 2, 17.

Research output: Contribution to journalReview article

Open Access
3 Scopus citations

Differentiating Peripherally-Located Small Cell Lung Cancer From Non-small Cell Lung Cancer Using a CT Radiomic Approach

Chen, B. T., Chen, Z., Ye, N., Mambetsariev, I., Fricke, J., Daniel, E., Wang, G., Wong, C. W., Rockne, R. C., Colen, R. R., Nasser, M. W., Batra, S. K., Holodny, A. I., Sampath, S. & Salgia, R., Apr 22 2020, In : Frontiers in Oncology. 10, 593.

Research output: Contribution to journalArticle

Open Access

DNA polymerase δ proofreads errors made by DNA polymerase e

Bulock, C. R., Xing, X. & Shcherbakova, P. V., Mar 17 2020, In : Proceedings of the National Academy of Sciences of the United States of America. 117, 11, p. 6035-6041 7 p.

Research output: Contribution to journalArticle

Open Access

Effects of selected deubiquitinating enzyme inhibitors on the proliferation and motility of lung cancer and mesothelioma cell lines

Mirzapoiazova, T., Pozhitkov, A., Nam, A., Mambetsariev, I., Nelson, M. S., Tan, Y. H. C., Zhang, K., Raz, D., Singhal, S., Nasser, M. W., Kulkarni, P., Batra, S. K., Sattler, M. & Salgia, R., Jul 2020, In : International journal of oncology. 57, 1, p. 80-86 7 p.

Research output: Contribution to journalArticle

EHD1 and RUSC2 control basal epidermal growth factor receptor cell surface expression and recycling

Tom, E. C., Mushtaq, I., Mohapatra, B. C., Luan, H., Bhat, A. M., Zutshi, N., Chakraborty, S., Islam, N., Arya, P., Bielecki, T. A., Iseka, F. M., Bhattacharyya, S., Cypher, L. R., Goetz, B. T., Negi, S. K., Storck, M. D., Rana, S., Barnekow, A., Singh, P. K., Ying, G. & 4 others, Guda, C., Natarajan, A., Band, V. & Banda, H., Apr 1 2020, In : Molecular and cellular biology. 40, 7, e00434.

Research output: Contribution to journalArticle

1 Scopus citations

Elevating pancreatic cystic lesion stratification: Current and future pancreatic cancer biomarker(s)

Carmicheal, J., Patel, A., Dalal, V., Atri, P., Dhaliwal, A. S., Wittel, U. A., Malafa, M. P., Talmon, G., Swanson, B. J., Singh, S., Jain, M., Kaur, S. & Batra, S. K., Jan 2020, In : Biochimica et Biophysica Acta - Reviews on Cancer. 1873, 1, 188318.

Research output: Contribution to journalReview article

Endocytic membrane trafficking in the control of centrosome function

Naslavsky, N. & Caplan, S., 2020, (Accepted/In press) In : Current Opinion in Cell Biology.

Research output: Contribution to journalReview article

Endogenous oxidized DNA bases and APE1 regulate the formation of G-quadruplex structures in the genome

Roychoudhury, S., Pramanik, S., Harris, H. L., Tarpley, M., Sarkar, A., Spagnol, G., Sorgen, P. L., Chowdhury, D., Band, V., Klinkebiel, D. & Bhakat, K. K., May 26 2020, In : Proceedings of the National Academy of Sciences of the United States of America. 117, 21, A44.

Research output: Contribution to journalArticle

Open Access

Endohyphal bacteria associated with virulence, increased expression of fumonisin biosynthetic genes, and production of fumonisin and macroconidia in Fusarium fujikuroi W343

Obasa, K., Adesemoye, A., Obasa, R., Moraga-Amador, D., Shinogle, H., Alvarez, S. & Kelley, K., Jan 1 2020, In : Plant Pathology. 69, 1, p. 87-100 14 p.

Research output: Contribution to journalArticle

Eradication of cancer stem cells in triple negative breast cancer using doxorubicin/pluronic polymeric micelles

Zhao, Y., Alakhova, D. Y., Zhao, X., Band, V., Batrakova, E. V. & Kabanov, A. V., Feb 2020, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 24, 102124.

Research output: Contribution to journalArticle

3 Scopus citations
Open Access

Final analysis of a phase 1/2b study of ibrutinib combined with carfilzomib/dexamethasone in patients with relapsed/refractory multiple myeloma

Chari, A., Cornell, R. F., Gasparetto, C., Karanes, C., Matous, J. V., Niesvizky, R., Lunning, M., Usmani, S. Z., Anderson, L. D., Chhabra, S., Girnius, S., Shustik, C., Stuart, R., Lee, Y., Salman, Z., Liu, E. & Valent, J., 2020, (Accepted/In press) In : Hematological Oncology.

Research output: Contribution to journalArticle

Open Access

Fluorescent Sensor Arrays Can Predict and Quantify the Composition of Multicomponent Bacterial Samples

Svechkarev, D., Sadykov, M. R., Houser, L. J., Bayles, K. W. & Mohs, A. M., Jan 15 2020, In : Frontiers in Chemistry. 7, 916.

Research output: Contribution to journalArticle

Open Access

Functional similarity of modified cascade impactor to deposit drug particles on cells

Kumar, V., Bariwal, J., Narang, A. S., Tso, J., Cheong, J. & Mahato, R. I., Jun 15 2020, In : International journal of pharmaceutics. 583, 1 p.

Research output: Contribution to journalArticle

Global dna hypomethylation in epithelial ovarian cancer: Passive demethylation and association with genomic instability

Zhang, W., Klinkebiel, D., Barger, C. J., Pandey, S., Guda, C., Miller, A., Akers, S. N., Odunsi, K. & Karpf, A. R., Mar 2020, In : Cancers. 12, 3, 764.

Research output: Contribution to journalArticle

Open Access

High-throughput identification of protein functional similarities using a gene-expression-based siRNA screen

Neilsen, B. K., Kelly, D. L., Chakraborty, B., Kim, H. S., White, M. A., Lewis, R. E. & Fisher, K. W., Dec 1 2020, In : Scientific Data. 7, 1, 27.

Research output: Contribution to journalArticle

Open Access

HLA-B influences integrin beta-1 expression and pancreatic cancer cell migration

Sliker, B. H., Goetz, B. T., Barnes, R., King, H., Maurer, H. C., Olive, K. P. & Solheim, J. C., May 15 2020, In : Experimental Cell Research. 390, 2, 111960.

Research output: Contribution to journalArticle

Homologous Recombination Repair Truncations Predict Hypermutation in Microsatellite Stable Colorectal and Endometrial Tumors

Lee, M., Eng, G., Barbari, S. R., Deshpande, V., Shcherbakova, P. V. & Gala, M. K., Mar 1 2020, In : Clinical and translational gastroenterology. 11, 3, p. e00149

Research output: Contribution to journalArticle

Open Access

IL-17–CXC Chemokine Receptor 2 Axis Facilitates Breast Cancer Progression by Up-Regulating Neutrophil Recruitment

Wu, L., Awaji, M., Saxena, S., Varney, M. L., Sharma, B. & Singh, R. K., Jan 2020, In : American Journal of Pathology. 190, 1, p. 222-233 12 p.

Research output: Contribution to journalArticle

2 Scopus citations

Image-guided tumor surgery: The emerging role of nanotechnology

Wojtynek, N. E. & Mohs, A. M., Jul 1 2020, In : Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology. 12, 4, e1624.

Research output: Contribution to journalReview article

Interaction of aβ42 with membranes triggers the self-assembly into oligomers

Banerjee, S., Hashemi, M., Zagorski, K. & Lyubchenko, Y. L., Feb 1 2020, In : International journal of molecular sciences. 21, 3, 1129.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Kilbournase, a protease-associated domain subtilase secreted by the fungal corn pathogen Stenocarpella maydis

Naumann, T. A., Naldrett, M. J. & Price, N. P. J., Aug 2020, In : Fungal Genetics and Biology. 141, 103399.

Research output: Contribution to journalArticle

Kinesin Kif2C in regulation of DNA double strand break dynamics and repair

Zhu, S., Paydar, M., Wang, F., Li, Y., Wang, L., Barrette, B., Bessho, T., Kwok, B. H. & Peng, A., Jan 2020, In : eLife. 9, e53402.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Lactate production by Staphylococcus aureus biofilm inhibits HDAC11 to reprogramme the host immune response during persistent infection

Heim, C. E., Bosch, M. E., Yamada, K. J., Aldrich, A. L., Chaudhari, S. S., Klinkebiel, D., Gries, C. M., Alqarzaee, A. A., Li, Y., Thomas, V. C., Seto, E., Karpf, A. R. & Kielian, T., 2020, (Accepted/In press) In : Nature Microbiology.

Research output: Contribution to journalArticle

Linking NRP2 With EMT and Chemoradioresistance in Bladder Cancer

Schulz, A., Gorodetska, I., Behrendt, R., Fuessel, S., Erdmann, K., Foerster, S., Datta, K., Mayr, T., Dubrovska, A. & Muders, M. H., Jan 21 2020, In : Frontiers in Oncology. 9, 1461.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations