Eppley Institute for Cancer Research

Research Output

AKT can be activated in the nucleus

Wang, R. & Brattain, M. G., Oct 2006, In : Cellular Signalling. 18, 10, p. 1722-1731 10 p.

Research output: Contribution to journalArticle

48 Scopus citations

Akt expression may predict favorable prognosis in cholangiocarcinoma

Javle, M. M., Yu, J., Khoury, T., Chadha, K. C., Iyer, R. V., Foster, J., Kuvshinoff, B. W., Gibbs, J. F., Geradts, J., Black, J. D. & Brattain, M. G., Nov 2006, In : Journal of Gastroenterology and Hepatology (Australia). 21, 11, p. 1744-1751 8 p.

Research output: Contribution to journalArticle

37 Scopus citations

Akt inhibitor MK-2206 promotes anti-tumor activity and cell death by modulation of AIF and Ezrin in colorectal cancer

Agarwal, E., Chaudhuri, A., Leiphrakpam, P. D., Haferbier, K. L., Brattain, M. G. & Chowdhury, S., Mar 1 2014, In : BMC cancer. 14, 1, 145.

Research output: Contribution to journalArticle

38 Scopus citations

Albumin, a new biomarker of organophosphorus toxicant exposure, identified by mass spectrometry

Peeples, E. S., Schopfer, L. M., Duysen, E. G., Spaulding, R., Voelker, T., Thompson, C. M. & Lockridge, O., Feb 2005, In : Toxicological Sciences. 83, 2, p. 303-312 10 p.

Research output: Contribution to journalArticle

113 Scopus citations

Albumin absorption by canine bronchial epithelium

Johnson, L. G., Cheng, P. W. & Boucher, R. C., 1989, In : Journal of Applied Physiology. 66, 6, p. 2772-2777 6 p.

Research output: Contribution to journalArticle

32 Scopus citations

Albumin Enhanced Morphometric Image Analysis CLL

Lunning, M. A., Zenger, V. E., Dreyfuss, R., Stetler-Stevenson, M., Rick, M. E., White, T. A., Wilson, W. H. & Marti, G. E., Jan 2004, In : Cytometry Part B - Clinical Cytometry. 57, 1, p. 7-14 8 p.

Research output: Contribution to journalReview article

12 Scopus citations

Alcohol and Smoking Mediated Modulations in Adaptive Immunity in Pancreatitis

Bhatia, R., Thompson, C., Ganguly, K., Singh, S., Batra, S. K. & Kumar, S., Aug 11 2020, In : Cells. 9, 8

Research output: Contribution to journalReview article

Open Access

Alcohol and tobacco lower the age of presentation in sporadic pancreatic cancer in a dose-dependent manner: A multicenter study

Anderson, M. A., Zolotarevsky, E., Cooper, K. L., Sherman, S., Shats, O., Whitcomb, D. C., Lynch, H. T., Ghiorzo, P., Rubinstein, W. S., Vogel, K. J., Sasson, A. R., Grizzle, W. E., Ketcham, M. A., Lee, S. Y., Normolle, D., Plonka, C. M., Mertens, A. N., Tripon, R. C. & Brand, R. E., Nov 2012, In : American Journal of Gastroenterology. 107, 11, p. 1730-1739 10 p.

Research output: Contribution to journalArticle

38 Scopus citations

Alendronate-Modified Polymeric Micelles for the Treatment of Breast Cancer Bone Metastasis

Liu, T., Romanova, S., Wang, S., Hyun, M. A., Zhang, C., Cohen, S. M., Singh, R. K. & Bronich, T. K., Jan 1 2019, In : Molecular Pharmaceutics.

Research output: Contribution to journalArticle

A leucine-rich repeat protein of carrot that exhibits antifreeze activity

Meyer, K., Keil, M. & Naldrett, M. J., Mar 26 1999, In : FEBS Letters. 447, 2-3, p. 171-178 8 p.

Research output: Contribution to journalArticle

96 Scopus citations

A linear 23-residue peptide reveals a propensity to form an unusual native-like conformation

Sherman, S. A., Gmeiner, W. H., Kirnarskiy, L., Perini, F. & Ruddon, R. W., Dec 1995, In : Journal of Biomolecular Structure and Dynamics. 13, 3, p. 441-446 6 p.

Research output: Contribution to journalArticle

9 Scopus citations

ALK - anaplastic large-cell lymphoma is clinically and immunophenotypically different from both ALK + ALCL and peripheral T-cell lymphoma, not otherwise specified: Report from the International Peripheral T-Cell Lymphoma Project

Savage, K. J., Harris, N. L., Vose, J. M., Ullrich, F., Jaffe, E. S., Connors, J. M., Rimsza, L., Pileri, S. A., Chhanabhai, M., Gascoyne, R. D., Armitage, J. O. & Weisenburger, D. D., Jun 15 2008, In : Blood. 111, 12, p. 5496-5504 9 p.

Research output: Contribution to journalArticle

578 Scopus citations

ALK-positive anaplastic large-cell lymphoma in adults: An individual patient data pooled analysis of 263 patients

Sibon, D., Nguyen, D. P., Schmitz, N., Suzuki, R., Feldman, A. L., Gressin, R., Lamant, L., Weisenburger, D. D., Rosenwald, A., Nakamura, S., Ziepert, M., Maurer, M. J., Bast, M., Armitage, J. O., Vose, J. M., Tilly, H., Jais, J. P. & Savage, K. J., 2019, In : Haematologica. 104, 12, p. E562-E565

Research output: Contribution to journalLetter

Open Access
4 Scopus citations

Allele frequency differences of cytochrome P450 polymorphisms in a sample of New Zealand Maori

Lea, R. A., Roberts, R. L., Green, M. R., Kennedy, M. A. & Chambers, G. K., Apr 18 2008, In : New Zealand Medical Journal. 121, 1272

Research output: Contribution to journalArticle

20 Scopus citations

Allelic exclusion of the TCR α-chain is an active process requiring TCR-mediated signaling and c-Cbl

Niederberger, N., Holmberg, K., Alam, S. M., Sakati, W., Naramura, M., Gu, H. & Gascoigne, N. R. J., May 1 2003, In : Journal of Immunology. 170, 9, p. 4557-4563 7 p.

Research output: Contribution to journalArticle

Open Access
22 Scopus citations

Allogeneic-blood stem-cell collection following mobilization with low- dose granulocyte colony-stimulating factor

Bishop, M. R., Tarantolo, S. R., Jackson, J. D., Anderson, J. R., Schmit-Pokorny, K., Zacharias, D., Pavletic, Z. S., Pirruccello, S. J., Vose, J. M., Bierman, P. J., Warkentin, P. I., Armitage, J. O. & Kessinger, A., Apr 1997, In : Journal of Clinical Oncology. 15, 4, p. 1601-1607 7 p.

Research output: Contribution to journalArticle

32 Scopus citations

Allogeneic Bone Marrow Transplantation: Problems and Prospects

Armitage, J. O., 1992, In : Mayo Clinic Proceedings. 67, 2, p. 195-197 3 p.

Research output: Contribution to journalEditorial

1 Scopus citations

Allogeneic bone marrow transplantation in patients with lymphoma relapsing after autologous marrow transplantation

Schouten, H. C., Armitage, J. O., Klassen, L. W., Vaughan, W. P., Bierman, P. J., Weisenburger, D. & Kessinger, A., 1989, In : Bone marrow transplantation. 4, 1, p. 119-121 3 p.

Research output: Contribution to journalArticle

15 Scopus citations
7 Scopus citations

Allogeneic transplantation of blood-derived, T cell-depleted hemopoietic stem cells after myeloablative treatment in a patient with acute lymphoblastic leukemia

Kessinger, A., Smith, D. M., Strandjord, S. E., Landmark, J. D., Dooley, D. C., Law, P., Coccia, P. F., Warkentin, P. I., Weisenburger, D. D. & Armitage, J. O., 1989, In : Bone marrow transplantation. 4, 6, p. 643-646 4 p.

Research output: Contribution to journalArticle

134 Scopus citations

Alloreactive and syngeneic CTL are comparably dependent on interaction with MHC class I α-helical residues

Hornell, T. M. C., Solheim, J. C., Myers, N. B., Gillanders, W. E., Balendiran, G. K., Hansen, T. H. & Connolly, J. M., Sep 15 1999, In : Journal of Immunology. 163, 6, p. 3217-3225 9 p.

Research output: Contribution to journalArticle

17 Scopus citations

Allosteric modulation of seven transmembrane spanning receptors: Theory, practice, and opportunities for central nervous system drug discovery

Melancon, B. J., Hopkins, C. R., Wood, M. R., Emmitte, K. A., Niswender, C. M., Christopoulos, A., Conn, P. J. & Lindsley, C. W., Feb 23 2012, In : Journal of Medicinal Chemistry. 55, 4, p. 1445-1464 20 p.

Research output: Contribution to journalReview article

169 Scopus citations

Allosteric modulation of the RNA polymerase catalytic reaction is an essential component of transcription control by rifamycins

Artsimovitch, I., Vassylyeva, M. N., Svetlov, D., Svetlov, V., Perederina, A., Igarashi, N., Matsugaki, N., Wakatsuki, S., Tahirov, T. H. & Vassylyev, D. G., Aug 12 2005, In : Cell. 122, 3, p. 351-363 13 p.

Research output: Contribution to journalArticle

129 Scopus citations

Allowance for heterogeneous stacking in the DNA helix-coil transition theory

Vologodskii, A. V., Amirikyan, B. R., Lyubchenko, Y. L. & Frank- Kamenetskii, M. D., 1984, In : Journal of Biomolecular Structure and Dynamics. 2, 1, p. 131-148 18 p.

Research output: Contribution to journalArticle

81 Scopus citations

Alpha-interferon for relapsed non-Hodgkin's lymphoma [2]

Armitage, A. E., Armitage, J. D. & Armitage, J. O., Nov 2006, In : Bone marrow transplantation. 38, 10, p. 701-702 2 p.

Research output: Contribution to journalLetter

12 Scopus citations

Alpha thalassemia/mental retardation syndrome X-linked gene product ATRX is required for proper replication restart and cellular resistance to replication stress

Leung, J. W. C., Ghosal, G., Wang, W., Shen, X., Wang, J., Li, L. & Chen, J., Mar 1 2013, In : Journal of Biological Chemistry. 288, 9, p. 6342-6350 9 p.

Research output: Contribution to journalArticle

49 Scopus citations

Alteration/deficiency in activation 3 (ADA3): Regulator of DNA repair and genome stability

Ghosal, G. & Chen, J., Dec 15 2012, In : Cell Cycle. 11, 24, p. 4496 1 p.

Research output: Contribution to journalComment/debate

Alteration/deficiency in activation-3 (Ada3) plays a critical role in maintaining genomic stability

Mirza, S., Katafiasz, B. J., Kumar, R., Wang, J., Mohibi, S., Jain, S., Gurumurthy, C. B., Pandita, T. K., Dave, B. J., Band, H. & Band, V., Nov 15 2012, In : Cell Cycle. 11, 22, p. 4266-4274 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

Alteration/deficiency in activation 3 (ADA3) protein, a cell cycle regulator, associates with the centromere through CENP-B and regulates chromosome segregation

Mohibi, S., Srivastava, S., Wang-France, J., Mirza, S., Zhao, X., Band, H. & Band, V., Nov 20 2015, In : Journal of Biological Chemistry. 290, 47, p. 28299-28310 12 p.

Research output: Contribution to journalArticle

7 Scopus citations

Alteration in expression of MUC2 and MUC3 mrna levels in HT29 colonic carcinoma cells

Mack, D. R. & Hollingsworth, M. A., Mar 15 1994, In : Biochemical and Biophysical Research Communications. 199, 2, p. 1012-1018 7 p.

Research output: Contribution to journalArticle

22 Scopus citations

Alteration in the behavior of a colon carcinoma cell line by extracellular matrix components

Boyd, D., Florent, G., Childress-Fields, K. & Brattain, M. G., Jul 1988, In : Cancer Letters. 41, 1, p. 81-90 10 p.

Research output: Contribution to journalArticle

10 Scopus citations

Alteration of genomic responses to doxorubicin and prevention of MDR in breast cancer cells by a polymer excipient: Pluronic P85

Batrakova, E. V., Kelly, D. L., Li, S., Li, Y., Yang, Z., Xiao, L., Alakhova, D. Y., Sherman, S., Alakhov, V. Y. & Kabanov, A. V., Mar 2006, In : Molecular Pharmaceutics. 3, 2, p. 113-123 11 p.

Research output: Contribution to journalArticle

65 Scopus citations

Alteration of glycoproteins released from human tracheal explants by methacholine stimulation

Boat, T. F. & Cheng, P. W., 1978, In : American Review of Respiratory Disease. 117, 4 II, p. 288 1 p.

Research output: Contribution to journalArticle

1 Scopus citations

Alteration of sulfation of glycoconjugates, but not sulfate transport and intracellular inorganic sulfate content in cystic fibrosis airway epithelial cells

Mohapatra, N. K., Cheng, P. W., John, J. C., Paradiso, A. M., Yankaskas, J. R., Boucher, R. C. & Boat, T. F., Jul 1995, In : Pediatric Research. 38, 1, p. 42-48 7 p.

Research output: Contribution to journalArticle

Open Access
27 Scopus citations

Alterations in c‐myc expression in relation to maturational status of human colon carcinoma cells

Mulder, K. M. & Brattain, M. G., Jul 15 1988, In : International Journal of Cancer. 42, 1, p. 64-70 7 p.

Research output: Contribution to journalArticle

40 Scopus citations
8 Scopus citations

Alterations in membrane protein glycosylation of human colonic carcinoma cells in conjunction with the development of a mitomycin C resistant phenotype

Miller, C., Brattain, D., Brattain, M. G. & Chakrabarty, S., 1984, In : Federation Proceedings. 43, 3, p. no. 1829

Research output: Contribution to journalArticle

Alterations in specificity of the glucocorticoid receptor with temperature in rat splenic lymphocytes

MacDonald, R. G. & Cidlowski, J. A., Jan 1979, In : Journal of Steroid Biochemistry. 10, 1, p. 21-29 9 p.

Research output: Contribution to journalArticle

22 Scopus citations

Alterations of EHD1/EHD4 protein levels interfere with L1/NgCAM endocytosis in neurons and disrupt axonal targeting

Yap, C. C. C., Lasiecka, Z. M., Caplan, S. & Winckler, B., May 12 2010, In : Journal of Neuroscience. 30, 19, p. 6646-6657 12 p.

Research output: Contribution to journalArticle

29 Scopus citations

Alterations of the biological characteristics of a colon carcinoma cell line by colon-derived substrata material

Boyd, D., Florent, G., Chakrabarty, S., Brattain, D. & Brattain, M. G., May 1988, In : Cancer Research. 48, 10, p. 2825-2831 7 p.

Research output: Contribution to journalArticle

30 Scopus citations

Altered expression of MUC2 and MUC5AC in response to Shigella infection, an in vivo study

Radhakrishnan, P., Halagowder, D. & Devaraj, S. N., Jun 2007, In : Biochimica et Biophysica Acta - General Subjects. 1770, 6, p. 884-889 6 p.

Research output: Contribution to journalArticle

14 Scopus citations

Altered expression of sialylated carbohydrate antigens in HT29 colonic carcinoma cells

Mack, D. R., Cheng, P. W., Perini, F., Wei, S. & Hollingsworth, M. A., 1998, In : Glycoconjugate Journal. 15, 12, p. 1155-1163 9 p.

Research output: Contribution to journalArticle

13 Scopus citations

Altered expression of transforming growth factor-α and transforming growth factor-β autocrine loops in cancer cells

Brattain, M. G., Mulder, K. M., Wu, S. P., Howell, G., Sun, L., Willson, J. K. V. & Ziober, B. L., Jan 1 1993, In : Advances in Molecular and Cell Biology. 7, C, p. 35-59 25 p.

Research output: Contribution to journalArticle

2 Scopus citations

Altered expression of transmembrane mucins, MUC1 and MUC4, in bladder cancer: Pathological implications in diagnosis

Kaur, S., Momi, N., Chakraborty, S., Wagner, D. G., Horn, A. J., Lele, S. M., Theodorescu, D. & Batra, S. K., Mar 26 2014, In : PloS one. 9, 3, e92742.

Research output: Contribution to journalArticle

23 Scopus citations
32 Scopus citations

Altered hippocampal muscarinic receptors in acetylcholinesterase-deficient mice

Volpicelli-Daley, L. A., Duysen, E. G., Lockridge, O. & Levey, A. I., Jun 1 2003, In : Annals of Neurology. 53, 6, p. 788-796 9 p.

Research output: Contribution to journalArticle

30 Scopus citations

Altered ligand binding by insulin-like growth factor II/mannose 6- phosphate receptors bearing missense mutations in human cancers

Devi, G. R., De Souza, A. T., Byrd, J. C., Jirtle, R. L. & MacDonald, R. G., Sep 1 1999, In : Cancer Research. 59, 17, p. 4314-4319 6 p.

Research output: Contribution to journalArticle

57 Scopus citations

Altered Mucins (MUC) trafficking in Benign and malignant conditions

Joshi, S., Kumar, S., Choudhury, A., Ponnusamy, M. P. & Batra, S. K., 2014, In : Oncotarget. 5, 17, p. 7272-7284 13 p.

Research output: Contribution to journalArticle

Open Access
23 Scopus citations

Altered recognition of antigen is a mechanism of CD8+ T cell tolerance in cancer

Nagaraj, S., Gupta, K., Pisarev, V., Kinarsky, L., Sherman, S., Kang, L., Herber, D. L., Schneck, J. & Gabrilovich, D. I., Jul 2007, In : Nature Medicine. 13, 7, p. 828-835 8 p.

Research output: Contribution to journalArticle

650 Scopus citations

Altered Striatal Function and Muscarinic Cholinergic Receptors in Acetylcholinesterase Knockout Mice

Volpicelli-Daley, L. A., Hrabovska, A., Duysen, E. G., Ferguson, S. M., Blakely, R. D., Lockridge, O. & Levey, A. I., Dec 2003, In : Molecular pharmacology. 64, 6, p. 1309-1316 8 p.

Research output: Contribution to journalArticle

51 Scopus citations