Eppley Institute for Cancer Research

Research Output

Article

Altered expression of transforming growth factor-α and transforming growth factor-β autocrine loops in cancer cells

Brattain, M. G., Mulder, K. M., Wu, S. P., Howell, G., Sun, L., Willson, J. K. V. & Ziober, B. L., Jan 1 1993, In : Advances in Molecular and Cell Biology. 7, C, p. 35-59 25 p.

Research output: Contribution to journalArticle

2 Scopus citations

Altered expression of transmembrane mucins, MUC1 and MUC4, in bladder cancer: Pathological implications in diagnosis

Kaur, S., Momi, N., Chakraborty, S., Wagner, D. G., Horn, A. J., Lele, S. M., Theodorescu, D. & Batra, S. K., Mar 26 2014, In : PloS one. 9, 3, e92742.

Research output: Contribution to journalArticle

23 Scopus citations
32 Scopus citations

Altered hippocampal muscarinic receptors in acetylcholinesterase-deficient mice

Volpicelli-Daley, L. A., Duysen, E. G., Lockridge, O. & Levey, A. I., Jun 1 2003, In : Annals of Neurology. 53, 6, p. 788-796 9 p.

Research output: Contribution to journalArticle

30 Scopus citations

Altered ligand binding by insulin-like growth factor II/mannose 6- phosphate receptors bearing missense mutations in human cancers

Devi, G. R., De Souza, A. T., Byrd, J. C., Jirtle, R. L. & MacDonald, R. G., Sep 1 1999, In : Cancer Research. 59, 17, p. 4314-4319 6 p.

Research output: Contribution to journalArticle

57 Scopus citations

Altered Mucins (MUC) trafficking in Benign and malignant conditions

Joshi, S., Kumar, S., Choudhury, A., Ponnusamy, M. P. & Batra, S. K., 2014, In : Oncotarget. 5, 17, p. 7272-7284 13 p.

Research output: Contribution to journalArticle

Open Access
23 Scopus citations

Altered recognition of antigen is a mechanism of CD8+ T cell tolerance in cancer

Nagaraj, S., Gupta, K., Pisarev, V., Kinarsky, L., Sherman, S., Kang, L., Herber, D. L., Schneck, J. & Gabrilovich, D. I., Jul 2007, In : Nature Medicine. 13, 7, p. 828-835 8 p.

Research output: Contribution to journalArticle

650 Scopus citations

Altered Striatal Function and Muscarinic Cholinergic Receptors in Acetylcholinesterase Knockout Mice

Volpicelli-Daley, L. A., Hrabovska, A., Duysen, E. G., Ferguson, S. M., Blakely, R. D., Lockridge, O. & Levey, A. I., Dec 2003, In : Molecular pharmacology. 64, 6, p. 1309-1316 8 p.

Research output: Contribution to journalArticle

51 Scopus citations

Altered thymic positive selection and intracellular signals in Cbl-deficient mice

Naramura, M., Kole, H. K., Hu, R. J. & Gu, H., Dec 22 1998, In : Proceedings of the National Academy of Sciences of the United States of America. 95, 26, p. 15547-15552 6 p.

Research output: Contribution to journalArticle

276 Scopus citations

Altered urinary excretion of elastin cross-links in premature infants who develop bronchopulmonary dysplasia

Bruce, M. C., Wedig, K. E., Jentoft, N., Martin, R. J., Cheng, P. W., Boat, T. F. & Fanaroff, A. A., 1985, In : American Review of Respiratory Disease. 131, 4, p. 568-572 5 p.

Research output: Contribution to journalArticle

62 Scopus citations

Altering the electrostatic potential in the major groove: Thermodynamic and structural characterization of 7-deaza-2′-deoxyadenosine:dT base pairing in DNA

Kowal, E. A., Ganguly, M., Pallan, P. S., Marky, L. A., Gold, B., Egli, M. & Stone, M. P., Dec 1 2011, In : Journal of Physical Chemistry B. 115, 47, p. 13925-13934 10 p.

Research output: Contribution to journalArticle

12 Scopus citations

Alternate splicing of the rTS gene product and its overexpression in a 5-fluorouracil-resistant cell line

Dolnick, B. J. & Black, A. R., Jul 15 1996, In : Cancer Research. 56, 14, p. 3207-3210 4 p.

Research output: Contribution to journalArticle

22 Scopus citations

Alternative splicing generates a family of putative secreted and membrane-associated MUC4 mucins

Moniaux, N., Escande, F., Batra, S. K., Porchet, N., Laine, A. & Aubert, J. P., 2000, In : European Journal of Biochemistry. 267, 14, p. 4536-4544 9 p.

Research output: Contribution to journalArticle

82 Scopus citations

Alu-polymerase chain reaction genomic fingerprinting technique identifies multiple genetic loci associated with pancreatic tumourigenesis

McKie, A. B., Iwamura, T., Leung, H. Y., Hollingsworth, M. A. & Lemoine, N. R., 1997, In : Genes Chromosomes and Cancer. 18, 1, p. 30-41 12 p.

Research output: Contribution to journalArticle

9 Scopus citations

A mammary-specific, long-range deletion on mouse chromosome 11 accelerates Brca1-associated mammary tumorigenesis

Triplett, A. A., Montagna, C. & Wagner, K. U., Dec 2008, In : Neoplasia. 10, 12, p. 1325-1334 10 p.

Research output: Contribution to journalArticle

14 Scopus citations

A medical health report on individuals with silent butyrylcholinesterase in the Vysya community of India

Manoharan, I., Boopathy, R., Darvesh, S. & Lockridge, O., Mar 2007, In : Clinica Chimica Acta. 378, 1-2, p. 128-135 8 p.

Research output: Contribution to journalArticle

68 Scopus citations

A micropapillary pattern is predictive of a poor prognosis in lung adenocarcinoma, and reduced surfactant apoprotein A expression in the micropapillary pattern is an excellent indicator of a poor prognosis

Tsutsumida, H., Nomoto, M., Goto, M., Kitajima, S., Kubota, I., Hirotsu, Y., Wakimoto, J., Hollingsworth, M. A. & Yonezawa, S., Jun 2007, In : Modern Pathology. 20, 6, p. 638-647 10 p.

Research output: Contribution to journalArticle

82 Scopus citations

Amides as bioisosteres of triazole-based geranylgeranyl diphosphate synthase inhibitors

Goetz, D. B., Varney, M. L., Wiemer, D. F. & Holstein, S. A., Aug 15 2020, In : Bioorganic and Medicinal Chemistry. 28, 16, 115604.

Research output: Contribution to journalArticle

Amino acid sequence of the active site of human serum cholinesterase from usual, atypical, and atypical-silent genotypes

Lockridge, O. & La Du, B. N., Jun 1986, In : Biochemical Genetics. 24, 5-6, p. 485-498 14 p.

Research output: Contribution to journalArticle

16 Scopus citations

Amino acid transporter SLC6A14 is a novel and effective drug target for pancreatic cancer

Coothankandaswamy, V., Cao, S., Xu, Y., Prasad, P. D., Singh, P. K., Reynolds, C. P., Yang, S., Ogura, J., Ganapathy, V. & Bhutia, Y. D., 2016, In : British Journal of Pharmacology. 173, 23, p. 3292-3306 15 p.

Research output: Contribution to journalArticle

35 Scopus citations

A mitotic CDK5-PP4 phospho-signaling cascade primes 53BP1 for DNA repair in G1

Zheng, X. F., Acharya, S. S., Choe, K. N., Nikhil, K., Adelmant, G., Satapathy, S. R., Sharma, S., Viccaro, K., Rana, S., Natarajan, A., Sicinski, P., Marto, J. A., Shah, K. & Chowdhury, D., Dec 1 2019, In : Nature communications. 10, 1, 4252.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

A model for the role of EHD1-containing membrane tubules in endocytic recycling

Sharma, M., Jovic, M., Kieken, F., Naslavsky, N., Sorgen, P. & Caplan, S., 2009, In : Communicative and Integrative Biology. 2, 5, p. 431-433 3 p.

Research output: Contribution to journalArticle

9 Scopus citations

A monoclonal antibody to rat liver cytochrome P450 IIC11 strongly and regiospecifically inhibits constitutive benzo[a]pyrene metabolism and DNA binding

Todorovic, R., Devanesan, P. D., Cavalieri, E. L., Rogan, E. G., Park, S. S. & Gelboin, H. V., 1991, In : Molecular Carcinogenesis. 4, 4, p. 308-314 7 p.

Research output: Contribution to journalArticle

13 Scopus citations

AMPH-1/Amphiphysin/Bin1 functions with RME-1/Ehd1 in endocytic recycling

Pant, S., Sharma, M., Patel, K., Caplan, S., Carr, C. M. & Grant, B. D., Dec 2009, In : Nature Cell Biology. 11, 12, p. 1399-1410 12 p.

Research output: Contribution to journalArticle

129 Scopus citations

Amphetamine anorexia and metoclopramide

Band, A. H. & Siddiqui, H. H., 1984, In : Indian Journal of Physiology and Pharmacology. 28, 1, p. 79-81 3 p.

Research output: Contribution to journalArticle

Amphiphilic polyanhydride-based recombinant MUC4β-nanovaccine activates dendritic cells

Banerjee, K., Gautam, S. K., Kshirsagar, P., Ross, K. A., Spagnol, G., Sorgen, P., Wannemuehler, M. J., Narasimhan, B., Solheim, J. C., Kumar, S., Batra, S. K. & Jain, M., 2019, In : Genes and Cancer. 10, 3-4, p. 52-62 11 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

AMPK promotes aberrant PGC1ß expression to support human colon tumor cell survival

Fisher, K. W., Das, B., Kim, H. S., Clymer, B. K., Gehring, D., Smith, D. R., Costanzo-Garvey, D. L., Fernandez, M. R., Brattain, M. G., Kelly, D. L., MacMillan, J., White, M. A. & Lewis, R. E., 2015, In : Molecular and cellular biology. 35, 22, p. 3866-3879 14 p.

Research output: Contribution to journalArticle

14 Scopus citations

A mutant of Dictyostelium mucoroides lacking the sorophore sheath and primary macrocyst wall

Larson, M. A., Kelly, D. L. & Weber, A. T., 1994, In : TRANS.AM.MICROSC.SOC.. 113, 2, p. 200-210 11 p.

Research output: Contribution to journalArticle

3 Scopus citations

A mutation linked with autism reveals a common mechanism of endoplasmic reticulum retention for the α,β-hydrolase fold protein family

De Jaco, A., Comoletti, D., Kovarik, Z., Gaietta, G., Radić, Z., Lockridge, O., Ellisman, M. H. & Taylor, P., Apr 7 2006, In : Journal of Biological Chemistry. 281, 14, p. 9667-9676 10 p.

Research output: Contribution to journalArticle

44 Scopus citations

Amyloid precursor-like protein 2 (APLP2) affects the actin cytoskeleton and increases pancreatic cancer growth and metastasis

Pandey, P., Rachagani, S., Das, S., Seshacharyulu, P., Sheinin, Y., Naslavsky, N., Pan, Z., Smith, B. L., Peters, H. L., Radhakrishnan, P., McKenna, N. R., Panapakkam Giridharan, S. S., Haridas, D., Kaur, S., Hollingsworth, M. A., MacDonald, R. G., Meza, J. L., Caplan, S., Batra, S. K. & Solheim, J. C., 2015, In : Oncotarget. 6, 4, p. 2064-2075 12 p.

Research output: Contribution to journalArticle

Open Access
15 Scopus citations

Amyloid precursor-like protein 2 association with HLA class i molecules

Tuli, A., Sharma, M., Wang, X., Simone, L. C., Capek, H. L., Cate, S., Hildebrand, W. H., Naslavsky, N., Caplan, S. & Solheim, J. C., Sep 2009, In : Cancer Immunology, Immunotherapy. 58, 9, p. 1419-1431 13 p.

Research output: Contribution to journalArticle

12 Scopus citations

Amyloid precursor-like protein 2 increases the endocytosis, instability, and turnover of the H2-Kd MHC class I molecule

Tuli, A., Sharma, M., McIlhaney, M. M., Talmadge, J. E., Naslavsky, N., Caplan, S. & Solheim, J. C., Aug 1 2008, In : Journal of Immunology. 181, 3, p. 1978-1987 10 p.

Research output: Contribution to journalArticle

Open Access
23 Scopus citations
8 Scopus citations

An adjunct mammary epithelial cell population in parous females: Its role in functional adaptation and tissue renewal

Wagner, K. U., Boulanger, C. A., Henry, M. L. D., Sgagias, M., Hennighausen, L. & Smith, G. H., 2002, In : Development. 129, 6, p. 1377-1386 10 p.

Research output: Contribution to journalArticle

215 Scopus citations

Analgesic Effects of the GIRK Activator, VU0466551, Alone and in Combination with Morphine in Acute and Persistent Pain Models

Abney, K. K., Bubser, M., Du, Y., Kozek, K. A., Bridges, T. M., Linsdley, C. W., Daniels, J. S., Morrison, R. D., Wickman, K., Hopkins, C. R., Jones, C. K. & Weaver, C. D., Mar 20 2019, In : ACS Chemical Neuroscience. 10, 3, p. 1294-1299 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

An alternative form of replication protein A expressed in normal human tissues supports DNA repair

Kemp, M. G., Mason, A. C., Carreira, A., Reardon, J. T., Haring, S. J., Borgstahl, G. E. O., Kowalczykowski, S. C., Sancar, A. & Wold, M. S., Feb 12 2010, In : Journal of Biological Chemistry. 285, 7, p. 4788-4797 10 p.

Research output: Contribution to journalArticle

18 Scopus citations

Analysis of 13 cell types reveals evidence for the expression of numerous novel primate- And tissue-specific microRNAs

Londina, E., Lohera, P., Telonis, A. G., Quann, K., Clark, P., Jinga, Y., Hatzimichael, E., Kirino, Y., Honda, S., Lally, M., Ramratnam, B., Comstock, C. E. S., Knudsen, K. E., Gomella, L., Spaeth, G. L., Hark, L., Katz, L. J., Witkiewicz, A., Rostami, A., Jimenez, S. A. & 18 others, Hollingsworth, M. A., Yeh, J. J., Shaw, C. A., McKenzie, S. E., Bray, P., Nelson, P. T., Zupo, S., Van Roosbroeck, K., Keating, M. J., Calin, G. A., Yeo, C., Jimbo, M., Cozzitorto, J., Brody, J. R., Delgrosso, K., Mattick, J. S., Fortina, P. & Rigoutsos, I., Mar 10 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 10, p. E1106-E1115

Research output: Contribution to journalArticle

244 Scopus citations

Analysis of high molecular weight human colon tumor antigens using monoclonal antibodies

Moosic, J. P., Taylor, C. W., Brattain, M. G. & Yeoman, L. C., 1985, In : Proceedings of the American Association for Cancer Research. VOL. 26, p. 1259 1 p.

Research output: Contribution to journalArticle

Analysis of major histocompatibility complex class I folding: Novel insights into intermediate forms

Simone, L. C., Tuli, A., Simone, P. D., Wang, X. & Solheim, J. C., Apr 2012, In : Tissue Antigens. 79, 4, p. 249-262 14 p.

Research output: Contribution to journalArticle

1 Scopus citations
13 Scopus citations

Analysis of normal epithelial cell specific-1 (NES1)/kallikrein 10 mRNA expression by in situ hybridization, a novel marker for breast cancer

Dhar, S., Bhargava, R., Yunes, M., Li, B., Goyal, J., Naber, S. P., Wazer, D. E. & Band, V., 2001, In : Clinical Cancer Research. 7, 11, p. 3393-3398 6 p.

Research output: Contribution to journalArticle

58 Scopus citations

Analysis of phage M13mp2 mutants produced from transfection of phage DNA having N4-aminocytosines at defined sequence positions

Matsumoto, K., Yashiki, T., Bessho, T., Negishi, K. & Hayatsu, H., Jul 1992, In : Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 268, 1, p. 59-64 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Analysis of potential biomarkers of estrogen-initiated cancer in the urine of Syrian golden hamsters treated with 4-hydroxyestradiol

Todorovic, R., Devanesan, P., Higginbotham, S., Zhao, J., Gross, M. L., Rogan, E. G. & Cavalieri, E. L., 2001, In : Carcinogenesis. 22, 6, p. 905-911 7 p.

Research output: Contribution to journalArticle

Open Access
41 Scopus citations

Analysis of potential phosphorylation sites in human T cell leukemia virus type 1 Tax

Boehm, A. K., Stawhecker, J. A., Semmes, O. J., Jankowski, P. E., Lewis, R. & Hinrichs, S. H., 1999, In : Journal of Biomedical Science. 6, 3, p. 206-212 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

Analysis of the human replication protein A:Rad52 complex: Evidence for crosstalk between RPA32, RPA70, Rad52 and DNA

Jackson, D., Dhar, K., Wahl, J. K., Wold, M. S. & Borgstahl, G. E. O., 2002, In : Journal of Molecular Biology. 321, 1, p. 133-148 16 p.

Research output: Contribution to journalArticle

51 Scopus citations

Analysis of the presenting features of adult acute leukemia: The French‐American‐British classification

Burns, C. P., Armitage, J. O., Frey, A. L., Dick, F. R., Jordan, J. E. & Woolson, R. F., May 15 1981, In : Cancer. 47, 10, p. 2460-2469 10 p.

Research output: Contribution to journalArticle

42 Scopus citations

An analysis of the somatic mosaic frequency in Drosophila melanogaster males and females

Mikheev, V. S. & Pavlov Yu., I., 1977, In : Genetika. 13, 9, p. 1673-1675 3 p.

Research output: Contribution to journalArticle

Anaplastic Multiple Myeloma: An Aggressive Variant With a Poor Response to Novel Therapies

Ammannagari, N., Celotto, K., Neppalli, V., Lee, K. & Holstein, S. A., Sep 1 2016, In : Clinical Lymphoma, Myeloma and Leukemia. 16, 9, p. e129-e131

Research output: Contribution to journalArticle

5 Scopus citations

An approach to membrane protein structure without crystals

Sorgen, P. L., Hu, Y., Guan, L., Kaback, H. R. & Girvin, M. E., Oct 29 2002, In : Proceedings of the National Academy of Sciences of the United States of America. 99, 22, p. 14037-14040 4 p.

Research output: Contribution to journalArticle

81 Scopus citations

Androgen-dependent peptides of the rat ventral prostate nuclear envelope

Venkatraman, J. T., Howell, G. M. & Lefebvre, Y. A., Dec 14 1984, In : Biochemical and Biophysical Research Communications. 125, 2, p. 469-474 6 p.

Research output: Contribution to journalArticle

7 Scopus citations