Eppley Institute for Cancer Research

Research Output

2018

Follicular large cleaved cell (centrocytic) lymphoma: an unrecognized variant of follicular lymphoma

El Behery, R., Laurini, J. A., Weisenburger, D. D., Smith, L. M., Dave, B. J., Yuan, J., Fu, K., Chan, W. C., Nathwani, B. N., Bierman, P. J., Bociek, R. G., Vose, J. M., Armitage, J. O., Greiner, T. C. & Aoun, P., Feb 2018, In : Human Pathology. 72, p. 180-190 11 p.

Research output: Contribution to journalArticle

2 Scopus citations

Functional analysis of cancer-associated DNA polymerase ε variants in Saccharomyces cerevisiae

Barbari, S. R., Kane, D. P., Moore, E. A. & Shcherbakova, P. V., Mar 1 2018, In : G3: Genes, Genomes, Genetics. 8, 3, p. 1019-1029 11 p.

Research output: Contribution to journalArticle

14 Scopus citations

Glycosylation of Cancer Stem Cells: Function in Stemness, Tumorigenesis, and Metastasis

Barkeer, S., Chugh, S., Batra, S. K. & Ponnusamy, M. P., Aug 2018, In : Neoplasia (United States). 20, 8, p. 813-825 13 p.

Research output: Contribution to journalReview article

13 Scopus citations

High-speed atomic force microscopy reveals structural dynamics of α -synuclein monomers and dimers

Zhang, Y., Hashemi, M., Lv, Z., Williams, B., Popov, K. I., Dokholyan, N. V. & Lyubchenko, Y. L., Mar 28 2018, In : Journal of Chemical Physics. 148, 12, 123322.

Research output: Contribution to journalArticle

21 Scopus citations

Hunting for transcription factors: STAT3 decoy in non-small cell lung cancer

Carmicheal, J., Kaur, S., Batra, S. K. & Ganti, A. K., Sep 1 2018, In : Translational Lung Cancer Research. 7, p. S254-S257

Research output: Contribution to journalReview article

1 Scopus citations

Hyaluronic acid formulation of near infrared fluorophores optimizes surgical imaging in a prostate tumor xenograft

Souchek, J. J., Wojtynek, N. E., Payne, W. M., Holmes, M. B., Dutta, S., Qi, B., Datta, K., LaGrange, C. A. & Mohs, A. M., Jul 15 2018, In : Acta Biomaterialia. 75, p. 323-333 11 p.

Research output: Contribution to journalArticle

12 Scopus citations

Hypoxia-induced metabolomic alterations in pancreatic cancer cells

Gunda, V., Kumar, S., Dasgupta, A. & Singh, P. K., 2018, Methods in Molecular Biology. Humana Press Inc., p. 95-105 11 p. (Methods in Molecular Biology; vol. 1742).

Research output: Chapter in Book/Report/Conference proceedingChapter

5 Scopus citations

Hypoxia-mediated in vivo tumor glucose uptake measurement and analysis

Shukla, S. K., Mulder, S. E. & Singh, P. K., 2018, Methods in Molecular Biology. Humana Press Inc., p. 107-113 7 p. (Methods in Molecular Biology; vol. 1742).

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Immunohistochemical expression profiles of mucin antigens in salivary gland mucoepidermoid carcinoma: MUC4- and MUC6-negative expression predicts a shortened survival in the early postoperative phase

Honjo, K., Hiraki, T., Higashi, M., Noguchi, H., Nomoto, M., Yoshimura, T., Batra, S. K., Yonezawa, S., Semba, I., Nakamura, N., Tanimoto, A. & Yamada, S., Feb 2018, In : Histology and Histopathology. 33, 2, p. 201-213 13 p.

Research output: Contribution to journalArticle

4 Scopus citations

Impact of miRNA-mRNA Profiling and Their Correlation on Medulloblastoma Tumorigenesis

Kumar, V., Kumar, V., Chaudhary, A. K., Coulter, D. W., McGuire, T. & Mahato, R. I., Sep 7 2018, In : Molecular Therapy - Nucleic Acids. 12, p. 490-503 14 p.

Research output: Contribution to journalArticle

5 Scopus citations

Increased Flexibility between Stems of Intramolecular Three-Way Junctions by the Insertion of Bulges

Carr, C. E. & Marky, L. A., Jun 19 2018, In : Biophysical journal. 114, 12, p. 2764-2774 11 p.

Research output: Contribution to journalArticle

2 Scopus citations

Indocyanine green loaded hyaluronan-derived nanoparticles for fluorescence-enhanced surgical imaging of pancreatic cancer

Qi, B., Crawford, A. J., Wojtynek, N. E., Holmes, M. B., Souchek, J. J., Almeida-Porada, G., Ly, Q. P., Cohen, S. M., Hollingsworth, M. A. & Mohs, A. M., Apr 2018, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 14, 3, p. 769-780 12 p.

Research output: Contribution to journalArticle

18 Scopus citations

Inhibiting crosstalk between MET signaling and mitochondrial dynamics and morphology: a novel therapeutic approach for lung cancer and mesothelioma

Wang, J., Mirzapoiazova, T., Carol Tan, Y. H., Pang, K. M., Pozhitkov, A., Wang, Y., Wang, Y., Mambetsariev, B., Wang, E., Nasser, M. W., Batra, S. K., Raz, D., Reckamp, K., Kulkarni, P., Zheng, Y. & Salgia, R., Nov 2 2018, In : Cancer Biology and Therapy. 19, 11, p. 1023-1032 10 p.

Research output: Contribution to journalArticle

4 Scopus citations

Insights into gemcitabine resistance and the potential for therapeutic monitoring

Gebregiworgis, T., Bhinderwala, F., Purohit, V., Chaika, N. V., Singh, P. K. & Powers, R., Dec 1 2018, In : Metabolomics. 14, 12, 156.

Research output: Contribution to journalArticle

6 Scopus citations

Intracellular amyloid beta expression leads to dysregulation of the mitogen-activated protein kinase and bone morphogenetic protein-2 signaling axis

Cruz, E., Kumar, S., Yuan, L., Arikkath, J. & Batra, S. K., Feb 2018, In : PloS one. 13, 2, e0191696.

Research output: Contribution to journalArticle

5 Scopus citations

Lipid-polymer hybrid nanocarriers for delivering cancer therapeutics

Date, T., Nimbalkar, V., Kamat, J., Mittal, A., Mahato, R. I. & Chitkara, D., Feb 10 2018, In : Journal of Controlled Release. 271, p. 60-73 14 p.

Research output: Contribution to journalReview article

26 Scopus citations

Loss of the nuclear pool of Ubiquitin ligase CHIP/STUB1 in breast cancer unleashes the MZF1-cathepsin pro-oncogenic program

Luan, H., Mohapatra, B., Bielecki, T. A., Mushtaq, I., Mirza, S., Jennings, T. A., Clubb, R. J., An, W., Ahmed, D., El-Ansari, R., Storck, M. D., Mishra, N. K., Guda, C., Sheinin, Y. M., Meza, J. L., Raja, S., Rakha, E. A., Band, V. & Band, H., May 15 2018, In : Cancer Research. 78, 10, p. 2524-2535 12 p.

Research output: Contribution to journalArticle

12 Scopus citations

Macrophage-derived neuropilin-2 exhibits novel tumor-promoting functions

Roy, S., Bag, A. K., Dutta, S., Polavaram, N. S., Islam, R., Schellenburg, S., Banwait, J., Guda, C., Ran, S., Hollingsworth, M. A., Singh, R. K., Talmadge, J. E., Muders, M. H., Batra, S. K. & Datta, K., Oct 1 2018, In : Cancer Research. 78, 19, p. 5600-5617 18 p.

Research output: Contribution to journalArticle

13 Scopus citations

Management of untreated advanced stage follicular lymphoma: Role of patient discernment

Umakanthan, J. M. & Lunning, M. A., Mar 2018, In : Best Practice and Research: Clinical Haematology. 31, 1, p. 23-30 8 p.

Research output: Contribution to journalReview article

1 Scopus citations

Mass Spectral Detection of Diethoxyphospho-Tyrosine Adducts on Proteins from HEK293 Cells Using Monoclonal Antibody depY for Enrichment

Onder, S., Schopfer, L. M., Tacal, O., Blake, T. A., Johnson, R. C. & Lockridge, O., Jun 18 2018, In : Chemical Research in Toxicology. 31, 6, p. 520-530 11 p.

Research output: Contribution to journalArticle

5 Scopus citations

MASTL induces Colon Cancer progression and Chemoresistance by promoting Wnt/β-catenin signaling

Uppada, S. B., Gowrikumar, S., Ahmad, R., Kumar, B., Szeglin, B., Chen, X., Smith, J. J., Batra, S. K., Singh, A. B. & Dhawan, P., Aug 1 2018, In : Molecular cancer. 17, 1, 111.

Research output: Contribution to journalArticle

19 Scopus citations

Mechanisms of erythrocyte development and regeneration: Implications for regenerative medicine and beyond

Bresnick, E. H., Hewitt, K. J., Mehta, C., Keles, S., Paulson, R. F. & Johnson, K. D., Jan 2018, In : Development (Cambridge). 145, 1, dev151423.

Research output: Contribution to journalReview article

11 Scopus citations

Metastatic cancers promote cachexia through ZIP14 upregulation in skeletal muscle

Wang, G., Biswas, A. K., Ma, W., Kandpal, M., Coker, C., Grandgenett, P. M., Hollingsworth, M. A., Jain, R., Tanji, K., López-Pintado, S., Borczuk, A., Hebert, D., Jenkitkasemwong, S., Hojyo, S., Davuluri, R. V., Knutson, M. D., Fukada, T. & Acharyya, S., Jun 1 2018, In : Nature Medicine. 24, 6, p. 770-781 12 p.

Research output: Contribution to journalArticle

34 Scopus citations

Met receptor inhibitor SU11274 localizes in the endoplasmic reticulum

Wiest, E. J., Smith, H. J. & Hollingsworth, M. A., Jul 2 2018, In : Biochemical and Biophysical Research Communications. 501, 4, p. 858-862 5 p.

Research output: Contribution to journalArticle

1 Scopus citations

MicroRNAs in the pathogenesis and treatment of progressive liver injury in NAFLD and liver fibrosis

Su, Q., Kumar, V., Sud, N. & Mahato, R. I., Apr 2018, In : Advanced Drug Delivery Reviews. 129, p. 54-63 10 p.

Research output: Contribution to journalReview article

28 Scopus citations

Microscale Gene Expression Analysis of Tumor-Associated Macrophages

Attri, K. S., Mehla, K., Shukla, S. K. & Singh, P. K., Dec 1 2018, In : Scientific reports. 8, 1, 2408.

Research output: Contribution to journalArticle

3 Scopus citations

Modulation of Cellular Response to Arsenic Trioxide Toxicity by Resveratrol

Mondal, B., Chen, H., Wen, W., Cavalieri, E. L., Rogan, E. G. & Zahid, M., May 21 2018, In : ACS Omega. 3, 5, p. 5511-5515 5 p.

Research output: Contribution to journalArticle

4 Scopus citations

Mouse pancreatic tumor model independent of tumor suppressor gene inactivation

Naramura, M. & Natarajan, A., May 1 2018, In : Pancreas. 47, 5, p. e27-e29

Research output: Contribution to journalLetter

MUC16 as a novel target for cancer therapy

Aithal, A., Rauth, S., Kshirsagar, P., Shah, A., Lakshmanan, I., Junker, W. M., Jain, M., Ponnusamy, M. P. & Batra, S. K., Aug 3 2018, In : Expert Opinion on Therapeutic Targets. 22, 8, p. 675-686 12 p.

Research output: Contribution to journalReview article

15 Scopus citations

Nanoscale dynamics of centromere nucleosomes and the critical roles of CENP-A

Stumme-Diers, M. P., Banerjee, S., Hashemi, M., Sun, Z. & Lyubchenko, Y. L., 2018, In : Nucleic acids research. 46, 1, p. 94-103 10 p.

Research output: Contribution to journalArticle

10 Scopus citations
6 Scopus citations

Natural products: A hope for glioblastoma patients

Vengoji, R., Macha, M. A., Batra, S. K. & Shonka, N. A., Apr 24 2018, In : Oncotarget. 9, 31, p. 22199-22224 26 p.

Research output: Contribution to journalReview article

25 Scopus citations

Novel CIL-102 derivatives as potential therapeutic agents for docetaxel-resistant prostate cancer

Miller, D. R., Tzeng, C. C., Farmer, T., Keller, E. T., Caplan, S., Chen, Y. S., Chen, Y. L. & Lin, M. F., Nov 1 2018, In : Cancer Letters. 436, p. 96-108 13 p.

Research output: Contribution to journalArticle

4 Scopus citations

Novel role of O-glycosyltransferases GALNT3 and B3GNT3 in the self-renewal of pancreatic cancer stem cells

Barkeer, S., Chugh, S., Karmakar, S., Kaushik, G., Rauth, S., Rachagani, S., Batra, S. K. & Ponnusamy, M. P., Nov 22 2018, In : BMC cancer. 18, 1, 1157.

Research output: Contribution to journalArticle

8 Scopus citations

NY-ESO-1 vaccination in combination with decitabine induces antigen-specific T-lymphocyte responses in patients with myelodysplastic syndrome

Griffiths, E. A., Srivastava, P., Matsuzaki, J., Brumberger, Z., Wang, E. S., Kocent, J., Miller, A., Roloff, G. W., Wong, H. Y., Paluch, B. E., Lutgen-Dunckley, L. G., Martens, B. L., Odunsi, K., Karpf, A. R., Hourigan, C. S. & Nemeth, M. J., Mar 1 2018, In : Clinical Cancer Research. 24, 5, p. 1019-1029 11 p.

Research output: Contribution to journalArticle

26 Scopus citations

O-GlcNAc Transferase Links Glucose Metabolism to MAVS-Mediated Antiviral Innate Immunity

Li, T., Li, X., Attri, K. S., Liu, C., Li, L., Herring, L. E., Asara, J. M., Lei, Y. L., Singh, P. K., Gao, C. & Wen, H., Dec 12 2018, In : Cell Host and Microbe. 24, 6, p. 791-803.e6

Research output: Contribution to journalArticle

16 Scopus citations

Optimization of cholinesterase-based catalytic bioscavengers against organophosphorus agents

Lushchekina, S. V., Schopfer, L. M., Grigorenko, B. L., Nemukhin, A. V., Varfolomeev, S. D., Lockridge, O. & Masson, P., Mar 13 2018, In : Frontiers in Pharmacology. 9, MAR, 211.

Research output: Contribution to journalArticle

14 Scopus citations

Organoid profiling identifies common responders to chemotherapy in pancreatic cancer

Tiriac, H., Belleau, P., Engle, D. D., Plenker, D., Deschênes, A., Somerville, T. D. D., Froeling, F. E. M., Burkhart, R. A., Denroche, R. E., Jang, G. H., Miyabayashi, K., Young, C. M., Patel, H., Ma, M., Lacomb, J. F., Palmaira, R. L. D., Javed, A. A., Huynh, J. C., Johnson, M., Arora, K. & 50 others, Robine, N., Shah, M., Sanghvi, R., Goetz, A. B., Lowder, C. Y., Martello, L., Driehuis, E., Lecomte, N., Askan, G., Iacobuzio-Donahue, C. A., Clevers, H., Wood, L. D., Hruban, R. H., Thompson, E., Aguirre, A. J., Wolpin, B. M., Sasson, A., Kim, J., Wu, M., Bucobo, J. C., Allen, P., Sejpal, D. V., Nealon, W., Sullivan, J. D., Winter, J. M., Gimotty, P. A., Grem, J. L., Dimaio, D. J., Buscaglia, J. M., Grandgenett, P. M., Brody, J. R., Hollingsworth, M. A., O’kane, G. M., Notta, F., Kim, E., Crawford, J. M., Devoe, C., Ocean, A., Wolfgang, C. L., Yu, K. H., Li, E., Vakoc, C. R., Hubert, B., Fischer, S. E., Wilson, J. M., Moffitt, R., Knox, J., Krasnitz, A., Gallinger, S. & Tuveson, D. A., Sep 2018, In : Cancer Discovery. 8, 9, p. 1112-1129 18 p.

Research output: Contribution to journalArticle

137 Scopus citations

p66Shc regulates migration of castration-resistant prostate cancer cells

Ingersoll, M. A., Chou, Y. W., Lin, J. S., Yuan, T. C., Miller, D. R., Xie, Y., Tu, Y., Oberley-Deegan, R. E., Batra, S. K. & Lin, M. F., Jun 2018, In : Cellular Signalling. 46, p. 1-14 14 p.

Research output: Contribution to journalArticle

9 Scopus citations

Pancreatic cancer associated with obesity and diabetes: An alternative approach for its targeting

Pothuraju, R., Rachagani, S., Junker, W. M., Chaudhary, S., Saraswathi, V., Kaur, S. & Batra, S. K., Dec 19 2018, In : Journal of Experimental and Clinical Cancer Research. 37, 1, 319.

Research output: Contribution to journalReview article

22 Scopus citations

Pathological and functional significance of Semaphorin-5A in pancreatic cancer progression and metastasis

Saxena, S., Hayashi, Y., Wu, L., Awaji, M., Atri, P., Varney, M. L., Purohit, A., Rachagani, S., Batra, S. K. & Singh, R. K., 2018, In : Oncotarget. 9, 5, p. 5931-5943 13 p.

Research output: Contribution to journalArticle

11 Scopus citations

PD2/PAF1 at the crossroads of the cancer network

Karmakar, S., Dey, P., Vaz, A. P., Bhaumik, S. R., Ponnusamy, M. P. & Batra, S. K., Jan 15 2018, In : Cancer Research. 78, 2, p. 313-319 7 p.

Research output: Contribution to journalReview article

8 Scopus citations

PD-L1, inflammation, non-coding RNAs, and neuroblastoma: Immuno-oncology perspective

Nallasamy, P., Chava, S., Verma, S. S., Mishra, S., Gorantla, S., Coulter, D. W., Byrareddy, S. N., Batra, S. K., Gupta, S. C. & Challagundla, K. B., Oct 2018, In : Seminars in Cancer Biology. 52, p. 53-65 13 p.

Research output: Contribution to journalReview article

11 Scopus citations

Pegaspargase-related high-grade hepatotoxicity in a pediatric-inspired adult acute lymphoblastic leukemia regimen does not predict recurrent hepatotoxicity with subsequent doses

Burke, P. W., Aldoss, I., Lunning, M. A., Devlin, S. M., Tallman, M. S., Pullarkat, V., Mohrbacher, A. M. & Douer, D., Mar 2018, In : Leukemia Research. 66, p. 49-56 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

Pharmacokinetics and biodistribution of polymeric micelles containing miRNA and small-molecule drug in orthotopic pancreatic tumor-bearing mice

Kumar, V., Mundra, V., Peng, Y., Wang, Y., Tan, C. & Mahato, R. I., 2018, In : Theranostics. 8, 15, p. 4033-4049 17 p.

Research output: Contribution to journalReview article

12 Scopus citations

Phase 1 trial of ibrutinib and carfilzomib combination therapy for relapsed or relapsed and refractory multiple myeloma

Chari, A., Larson, S., Holkova, B., Cornell, R. F., Gasparetto, C., Karanes, C., Matous, J. V., Niesvizky, R., Valent, J., Lunning, M., Usmani, S. Z., Anderson, L. D., Chang, L., Lee, Y., Pak, Y., Salman, Z., Graef, T., Bilotti, E. & Chhabra, S., Nov 2 2018, In : Leukemia and Lymphoma. 59, 11, p. 2588-2594 7 p.

Research output: Contribution to journalArticle

11 Scopus citations

Phosphoinositide 3-kinase signaling pathway in pancreatic ductal adenocarcinoma progression, pathogenesis, and therapeutics

Murthy, D., Attri, K. S. & Singh, P. K., Apr 4 2018, In : Frontiers in Physiology. 9, APR, 335.

Research output: Contribution to journalReview article

18 Scopus citations

Polymer nanoarray approach for the characterization of biomolecular interactions

Maity, S., Viazovkina, E., Gall, A. & Lyubchenko, Y. L., 2018, Methods in Molecular Biology. Humana Press Inc., p. 63-74 12 p. (Methods in Molecular Biology; vol. 1814).

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Scopus citations

Precision Medicine for CRC Patients in the Veteran Population: State-of-the-Art, Challenges and Research Directions

Mohapatra, S. S., Batra, S. K., Bharadwaj, S., Bouvet, M., Cosman, B., Goel, A., Jogunoori, W., Kelley, M. J., Mishra, L., Mishra, B., Mohapatra, S., Patel, B., Pisegna, J. R., Raufman, J. P., Rao, S., Roy, H., Scheuner, M., Singh, S., Vidyarthi, G. & White, J., May 1 2018, In : Digestive Diseases and Sciences. 63, 5, p. 1123-1138 16 p.

Research output: Contribution to journalReview article

4 Scopus citations