Gene Expression Laboratory

Research output

Research output per year 1987 1990 1996 2000 2002 2003 2004 2005 2006 2007 2009 2010 2012 2014 2016 2020 2020

• 62 Article
• 4 Review article
• 2 Comment/debate
• 1 Editorial
• 2 More
  • 1 Letter
  • 1 Short survey

Research output per year

Research output per year

Search results

• 2020

  Erratum: Human α1 type IV collagen NC1 domain exhibits distinct antiangiogenic activity mediated by α1β1 integrin (Journal of Clinical Investigation (2005) 115:10 (2801–2810) DOI: 10.1172/JCI24813)

  Sudhakar, A., Nyberg, P., Keshamouni, V. G., Mannam, A. P., Li, J., Sugimoto, H., Cosgrove, D. & Kalluri, R., Jan 2 2020, In: Journal of Clinical Investigation. 130, 1, p. 552 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  • United States Office of Research Integrity 100%
  • Collagen Type I 51%
  • Integrins 47%
  1 Scopus citations

• Pericyte abnormalities precede strial capillary basement membrane thickening in Alport mice

  Dufek, B., Meehan, D. T., Delimont, D., Samuelson, G., Madison, J., Shi, X., Boettcher, F., Trosky, V., Gratton, M. A. & Cosgrove, D., May 2020, In: Hearing Research. 390, 107935.

  Research output: Contribution to journal › Article › peer-review

  • Pericytes 100%
  • Basement Membrane 80%
  • Capillaries 78%
  • Stria Vascularis 33%
  • Actins 29%
  4 Scopus citations

• RNA-seq analysis of gene expression profiles in isolated stria vascularis from wild-type and Alport mice reveals key pathways underling Alport strial pathogenesis

  Dufek, B., Meehan, D. T., Delimont, D., Wilhelm, K., Samuelson, G., Coenen, R., Madison, J., Doyle, E., Smyth, B., Phillips, G., Gratton, M. A. & Cosgrove, D., Aug 2020, In: PloS one. 15, 8 August 2020, e0237907.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Stria Vascularis 100%
  • RNA-Seq 80%
  • Transcriptome 63%
  • Noise-Induced Hearing Loss 37%
  • Genes 27%
  4 Scopus citations
• 2018

  Lysyl oxidase like-2 contributes to renal fibrosis in Col4α3/Alport mice

  Cosgrove, D., Dufek, B., Meehan, D. T., Delimont, D., Hartnett, M., Samuelson, G., Gratton, M. A., Phillips, G., MacKenna, D. A. & Bain, G., Aug 2018, In: Kidney International. 94, 2, p. 303-314 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Protein-Lysine 6-Oxidase 100%
  • Fibrosis 51%
  • Glomerular Basement Membrane 38%
  • Kidney 37%
  • Matrix Metalloproteinases 29%
  37 Scopus citations
• 2017

  Collagen IV diseases: A focus on the glomerular basement membrane in Alport syndrome

  Cosgrove, D. & Liu, S., Jan 1 2017, In: Matrix Biology. 57-58, p. 45-54 10 p.

  Research output: Contribution to journal › Review article › peer-review

  • Hereditary Nephritis 100%
  • Collagen Diseases 91%
  • Glomerular Basement Membrane 86%
  • Collagen Type IV 81%
  • Basement Membrane 67%
  84 Scopus citations
• 2016

  Endothelin-1 mediated induction of extracellular matrix genes in strial marginal cells underlies strial pathology in Alport mice

  Meehan, D. T., Delimont, D., Dufek, B., Zallocchi, M., Phillips, G., Gratton, M. A. & Cosgrove, D., Nov 1 2016, In: Hearing Research. 341, p. 100-108 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Endothelin-1 100%
  • Extracellular Matrix 77%
  • Basement Membrane 64%
  • Pathology 58%
  • Endothelin A Receptors 53%
  20 Scopus citations

• Endothelin A receptor activation on mesangial cells initiates Alport glomerular disease

  Dufek, B., Meehan, D. T., Delimont, D., Cheung, L., Gratton, M. A., Phillips, G., Song, W., Liu, S. & Cosgrove, D., Aug 1 2016, In: Kidney International. 90, 2, p. 300-310 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Endothelin A Receptors 100%
  • Glomerular Basement Membrane 92%
  • Mesangial Cells 88%
  • Pseudopodia 88%
  • Endothelin-1 79%
  40 Scopus citations

• X-linked alport dogs demonstrate mesangial filopodial invasion of the capillary tuft as an early event in glomerular damage

  Clark, S. D., Nabity, M. B., Cianciolo, R. E., Dufek, B. & Cosgrove, D., Dec 2016, In: PloS one. 11, 12, e0168343.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Hereditary Nephritis 100%
  • Fibronectin 82%
  • proteinuria 72%
  • Interstitial 71%
  • Capillaries 66%
  12 Scopus citations
• 2014

  EIAV-based retinal gene therapy in the shaker1 mouse model for usher syndrome type 1B: Development of UshStat

  Zallocchi, M., Binley, K., Lad, Y., Ellis, S., Widdowson, P., Iqball, S., Scripps, V., Kelleher, M., Loader, J., Miskin, J., Peng, Y. W., Wang, W. M., Cheung, L., Delimont, D., Mitrophanous, K. A. & Cosgrove, D., Apr 4 2014, In: PloS one. 9, 4, e94272.

  Research output: Contribution to journal › Article › peer-review

  • Type 1B Usher syndrome 100%
  • Equine infectious anemia virus 78%
  • gene therapy 69%
  • Retinal 56%
  • photoreceptors 50%
  84 Scopus citations

• Laminin α2-mediated focal adhesion kinase activation triggers Alport glomerular pathogenesis

  Delimont, D., Dufek, B. M., Meehan, D. T., Zallocchi, M., Gratton, M. A., Phillips, G. & Cosgrove, D., Jun 10 2014, In: PloS one. 9, 6, e99083.

  Research output: Contribution to journal › Article › peer-review

  • Focal Adhesion Kinase 2 100%
  • non-specific protein-tyrosine kinase 94%
  • laminin 78%
  • Phosphotransferase Inhibitor 77%
  • Laminin 67%
  42 Scopus citations

• Photoreceptors in whirler mice show defective transducin translocation and are susceptible to short-term light/dark changes-induced degeneration

  Tian, M., Wang, W., Delimont, D., Cheung, L., Zallocchi, M., Cosgrove, D. & Peng, Y. W., Jan 2014, In: Experimental Eye Research. 118, p. 145-153 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Transducin 100%
  • Light 48%
  • Usher Syndromes 44%
  • Autosomal Recessive 31 Deafness 20%
  • Retinal Photoreceptor Cell Inner Segment 16%
  18 Scopus citations

• Usher protein functions in hair cells and photoreceptors

  Cosgrove, D. & Zallocchi, M., Jan 2014, In: International Journal of Biochemistry and Cell Biology. 46, 1, p. 80-89 10 p.

  Research output: Contribution to journal › Review article › peer-review

  • Photoreceptor Cells 100%
  • Usher Syndromes 69%
  • Stereocilia 50%
  • Protein 32%
  • Proteins 29%
  76 Scopus citations
• 2013

  Light-Induced Translocation of RGS9-1 and Gβ5L in Mouse Rod Photoreceptors

  Tian, M., Zallocchi, M., Wang, W., Chen, C. K., Palczewski, K., Delimont, D., Cosgrove, D. & Peng, Y. W., Mar 28 2013, In: PloS one. 8, 3, e58832.

  Research output: Contribution to journal › Article › peer-review

  • Dark Adaptation 100%
  • dark adaptation 95%
  • Retinal Rod Photoreceptor Cells 92%
  • rods (retina) 81%
  • Rod Like Crystal 64%
  12 Scopus citations

• α1β1 Integrin/rac1-dependent mesangial invasion of glomerular capillaries in alport syndrome

  Zallocchi, M., Johnson, B. M., Meehan, D. T., Delimont, D. & Cosgrove, D., Oct 2013, In: American Journal of Pathology. 183, 4, p. 1269-1280 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Hereditary Nephritis 100%
  • Laminin 74%
  • Capillaries 66%
  • Mesangial Cells 65%
  • Integrins 64%
  31 Scopus citations
• 2012

  Glomerular pathology in Alport syndrome: A molecular perspective

  Cosgrove, D., Jun 2012, In: Pediatric Nephrology. 27, 6, p. 885-890 6 p.

  Research output: Contribution to journal › Review article › peer-review

  • Hereditary Nephritis 100%
  • Glomerular Basement Membrane 86%
  • Pathology 43%
  • Disease Progression 40%
  • Collagen Type VI 26%
  30 Scopus citations

• Regulated vesicular trafficking of specific PCDH15 and VLGR1 variants in auditory hair cells

  Zallocchi, M., Delimont, D., Meehan, D. T. & Cosgrove, D., Oct 3 2012, In: Journal of Neuroscience. 32, 40, p. 13841-13859 19 p.

  Research output: Contribution to journal › Article › peer-review

  • Auditory Hair Cells 100%
  • Stereocilia 41%
  • Proteins 25%
  • Usher Syndromes 21%
  • Hearing Disorders 20%
  20 Scopus citations

• Role for a novel Usher protein complex in hair cell synaptic maturation

  Zallocchi, M., Meehan, D. T., Delimont, D., Rutledge, J., Gratton, M. A., Flannery, J. & Cosgrove, D., Feb 17 2012, In: PloS one. 7, 2, e30573.

  Research output: Contribution to journal › Article › peer-review

  • cadherins 100%
  • Cadherins 75%
  • G-Protein-Coupled Receptors 75%
  • Stereocilia 74%
  • hairs 70%
  39 Scopus citations
• 2011

  Moderate Light-Induced Degeneration of Rod Photoreceptors with Delayed Transducin Translocation in shaker1 Mice

  Peng, Y. W., Zallocchi, M., Wang, W. M., Delimont, D. & Cosgrove, D., Aug 2011, In: Investigative Ophthalmology and Visual Science. 52, 9, p. 6421-6427 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Transducin 100%
  • Retinal Rod Photoreceptor Cells 90%
  • Light 48%
  • Usher Syndromes 34%
  • Myosin VIIa 20%
  38 Scopus citations
• 2010

  Biochemical characterization of native usher protein complexes from a vesicular subfraction of tracheal epithelial cells

  Zallocchi, M., Sisson, J. H. & Cosgrove, D., Feb 16 2010, In: Biochemistry. 49, 6, p. 1236-1247 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Epithelial Cells 100%
  • Transport Vesicles 72%
  • Protein 57%
  • rab5 GTP-Binding Proteins 51%
  • Proteins 51%
  13 Scopus citations

• Clarin-1 protein expression in photoreceptors

  Cosgrove, D. & Zallocchi, M., Jan 2010, In: Hearing Research. 259, 1-2, p. 117 1 p.

  Research output: Contribution to journal › Letter › peer-review
  3 Scopus citations

• Collagen XIII induced in vascular endothelium mediates α1β1 integrin-dependent transmigration of monocytes in renal fibrosis

  Dennis, J., Meehan, D. T., Delimont, D., Zallocchi, M., Perry, G. A., O'Brien, S., Tu, H., Pihlajaniemi, T. & Cosgrove, D., Nov 2010, In: American Journal of Pathology. 177, 5, p. 2527-2540 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Vascular Endothelium 100%
  • Integrins 85%
  • Monocytes 74%
  • Collagen 68%
  • Fibrosis 67%
  33 Scopus citations
• 2009

  Biomechanical strain causes maladaptive gene regulation, contributing to alport glomerular disease

  Meehan, D. T., Delimont, D., Cheung, L., Zallocchi, M., Sansom, S. C., Holzclaw, J. D., Rao, V. & Cosgrove, D., Nov 2009, In: Kidney International. 76, 9, p. 968-976 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Matrix Metalloproteinase 3 100%
  • Matrix Metalloproteinase 10 87%
  • Glomerular Basement Membrane 66%
  • Podocytes 64%
  • Interleukin-6 60%
  54 Scopus citations

• Localization and expression of clarin-1, the Clrn1 gene product, in auditory hair cells and photoreceptors

  Zallocchi, M., Meehan, D. T., Delimont, D., Askew, C., Garige, S., Gratton, M. A., Rothermund-Franklin, C. A. & Cosgrove, D., Sep 2009, In: Hearing Research. 255, 1-2, p. 109-120 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Auditory Hair Cells 100%
  • Protein Isoforms 56%
  • Cochlea 43%
  • Retina 36%
  • Genes 28%
  43 Scopus citations

• Stem cell therapy for Alport syndrome: The hope beyond the hype

  Gross, O., Borza, D. B., Anders, H. J., Licht, C., Weber, M., Segerer, S., Torra, R., Gubler, M. C., Heidet, L., Harvey, S., Cosgrove, D., Lees, G., Kashtan, C., Gregory, M., Savige, J., Ding, J., Thorner, P., Abrahamson, D. R., Antignac, C., Tryggvason, K., & 2 othersHudson, B. & Miner, J. H., Mar 2009, In: Nephrology Dialysis Transplantation. 24, 3, p. 731-734 4 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  37 Scopus citations
• 2008

  Integrin α1β1 regulates matrix metalloproteinases via p38 mitogen-activated protein kinase in mesangial cells: Implications for alport syndrome

  Cosgrove, D., Meehan, D. T., Delimont, D., Pozzi, A., Chen, X., Rodgers, K. D., Tempero, R. M., Zallocchi, M. & Rao, V. H., Mar 2008, In: American Journal of Pathology. 172, 3, p. 761-773 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Matrix Metalloproteinase 11 100%
  • Hereditary Nephritis 87%
  • Mesangial Cells 71%
  • p38 Mitogen-Activated Protein Kinases 61%
  • Integrins 56%
  32 Scopus citations

• Progressive morphological and functional defects in retinas from α1 integrin-null mice

  Peng, Y. W., Zallocchi, M., Meehan, D. T., Delimont, D., Chang, B., Hawes, N., Wang, W. & Cosgrove, D., Oct 2008, In: Investigative Ophthalmology and Visual Science. 49, 10, p. 4647-4654 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Integrins 100%
  • Retina 91%
  • Basement Membrane 62%
  • Transducin 46%
  • Retinal Pigments 38%
  13 Scopus citations
• 2007

  A complex, tissue-specific role for plasmin and its regulators in modulating fibrogenic activity

  Cosgrove, D., Jul 2007, In: American Journal of Physiology - Renal Physiology. 293, 1, p. F10-F11

  Research output: Contribution to journal › Editorial › peer-review
  2 Scopus citations

• Choosing a mouse model to study the molecular pathobiology of Alport glomerulonephritis

  Cosgrove, D., Kalluri, R., Miner, J. H., Segal, Y. & Borza, D. B., Apr 2007, In: Kidney International. 71, 7, p. 615-618 4 p.

  Research output: Contribution to journal › Short survey › peer-review

  • Hereditary Nephritis 100%
  • Glomerulonephritis 72%
  • Glomerular Basement Membrane 57%
  • Collagen 25%
  • Dogs 24%
  47 Scopus citations

• Regulation of COX-2-mediated signaling by α3 type IV noncollagenous domain in tumor angiogenesis

  Boosani, C. S., Mannam, A. P., Cosgrove, D., Silva, R., Hodivala-Dilke, K. M., Keshamouni, V. G. & Sudhakar, A., Aug 15 2007, In: Blood. 110, 4, p. 1168-1177 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Cyclooxygenase 2 100%
  • Integrins 89%
  • Neoplasms 30%
  • Endothelial Cells 25%
  • Null Lymphocytes 22%
  43 Scopus citations
• 2006

  Bone-marrow-derived stem cells repair basement membrane collagen defects and reverse genetic kidney disease

  Sugimoto, H., Mundel, T. M., Sund, M., Xie, L., Cosgrove, D. & Kalluri, R., May 9 2006, In: Proceedings of the National Academy of Sciences of the United States of America. 103, 19, p. 7321-7326 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Reverse Genetics 100%
  • Glomerular Basement Membrane 95%
  • Kidney Diseases 79%
  • Basement Membrane 74%
  • Inborn Genetic Diseases 69%
  218 Scopus citations

• Role for macrophage metalloelastase in glomerular basement membrane damage associated with Alport syndrome

  Rao, V. H., Meehan, D. T., Delimont, D., Nakajima, M., Wada, T., Gratton, M. A. & Cosgrove, D., Jul 2006, In: American Journal of Pathology. 169, 1, p. 32-46 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Matrix Metalloproteinase 12 100%
  • Hereditary Nephritis 93%
  • Glomerular Basement Membrane 80%
  • Matrix Metalloproteinases 61%
  • CCR2 Receptors 48%
  70 Scopus citations

• Stage-specific action of matrix metalloproteinases influences progressive hereditary kidney disease

  Zeisberg, M., Khurana, M., Rao, V. H., Cosgrove, D., Rougier, J. P., Werner, M. C., Shield, C. F., Werb, Z. & Kalluri, R., Apr 2006, In: PLoS Medicine. 3, 4, p. 535-546 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Glomerular Basement Membrane 100%
  • Kidney Diseases 83%
  • Matrix Metalloproteinases 76%
  • Inborn Genetic Diseases 73%
  • Proteinuria 63%
  123 Scopus citations
• 2005

  Dysregulation of renal MMP-3 and MMP-7 in canine X-linked Alport syndrome

  Rao, V. H., Lees, G. E., Kashtan, C. E., Delimont, D. C., Singh, R., Meehan, D. T., Bhattacharya, G., Berridge, B. R. & Cosgrove, D., Jun 2005, In: Pediatric Nephrology. 20, 6, p. 732-739 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Hereditary Nephritis 100%
  • Matrix Metalloproteinase 7 98%
  • Matrix Metalloproteinase 3 86%
  • Canidae 59%
  • Matrix Metalloproteinase 2 37%
  12 Scopus citations

• Evidence for functional importance of usherin/fibronectin interactions in retinal basement membranes

  Bhattacharya, G. & Cosgrove, D., Aug 30 2005, In: Biochemistry. 44, 34, p. 11518-11524 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Usher Syndromes 100%
  • Fibronectin 78%
  • Retinal 74%
  • Basement Membrane 64%
  • Fibronectins 63%
  21 Scopus citations

• Extracellular matrix and inner ear development and function

  Cosgrove, D. & Anne Gratton, M., 2005, In: Advances in Developmental Biology. 15, p. 169-201 33 p.

  Research output: Contribution to journal › Article › peer-review

  • Thickening 100%
  • Ablation 93%
  • Inner Ear 87%
  • Cochlea 84%
  • Basement Membrane 79%
  1 Scopus citations

• Human α1 type IV collagen NC1 domain exhibits distinct antiangiogenic activity mediated by α1β1 integrin

  Sudhakar, A., Nyberg, P., Keshamouni, V. G., Mannam, A. P., Li, J., Sugimoto, H., Cosgrove, D. & Kalluri, R., Oct 2005, In: Journal of Clinical Investigation. 115, 10, p. 2801-2810 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Collagen Type I 100%
  • Integrins 93%
  • Collagen Type IV 59%
  • Hypoxia 39%
  • p38 Mitogen-Activated Protein Kinases 34%
  138 Scopus citations

• Matrix metalloproteinase dysregulation in the stria vascularis of mice with Alport syndrome: Implications for capillary basement membrane pathology

  Gratton, M. A., Rao, V. H., Meehan, D. T., Askew, C. & Cosgrove, D., May 2005, In: American Journal of Pathology. 166, 5, p. 1465-1474 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Hereditary Nephritis 100%
  • Stria Vascularis 99%
  • Basement Membrane 67%
  • Matrix Metalloproteinases 65%
  • Cochlea 47%
  38 Scopus citations
• 2004

  A domain-specific usherin/collagen IV interaction may be required for stable integration into the basement membrane superstructure

  Bhattacharya, G., Kalluri, R., Orten, D. J., Kimberling, W. J. & Cosgrove, D., Jan 15 2004, In: Journal of cell science. 117, 2, p. 233-242 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Collagen Type IV 100%
  • Basement Membrane 82%
  • Collagen 63%
  • Usher Syndromes 42%
  • Deaf-Blind Disorders 22%
  44 Scopus citations

• Immunohistochemistry and reverse transcriptase-polymerase chain reaction as methods for diagnostic determination of Usher syndrome type IIa

  Cohn, E., Bhattacharya, G., Pearsall, N., Shendrik, I., Kimberling, W. & Cosgrove, D., Jul 2004, In: Laryngoscope. 114, 7, p. 1310-1314 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Usher Syndromes 100%
  • Minor Salivary Glands 73%
  • Reverse Transcriptase Polymerase Chain Reaction 66%
  • Immunohistochemistry 45%
  • Loss of Function Mutation 24%
  2 Scopus citations

• Lack of integrin α1β1 leads to severe glomerulosclerosis after glomerular injury

  Chen, X., Moeckel, G., Morrow, J. D., Cosgrove, D., Harris, R. C., Fogo, A. B., Zent, R. & Pozzi, A., Aug 2004, In: American Journal of Pathology. 165, 2, p. 617-630 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Integrins 100%
  • Reactive Oxygen Species 67%
  • Wounds and Injuries 51%
  • Collagen 48%
  • Fibrosis 47%
  86 Scopus citations
• 2003

  Increased expression of MMP-2, MMP-9 (type IV collagenases/gelatinases), and MT1-MMP in canine X-linked Alport syndrome (XLAS)

  Rao, V. H., Lees, G. E., Kashtan, C. E., Nemori, R., Singh, R. K., Meehan, D. T., Rodgers, K., Berridge, B. R., Bhattacharya, G. & Cosgrove, D. E., May 1 2003, In: Kidney International. 63, 5, p. 1736-1748 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Hereditary Nephritis 100%
  • Gelatinases 91%
  • Matrix Metalloproteinase 2 75%
  • Collagenases 74%
  • Matrix Metalloproteinase 9 73%
  53 Scopus citations

• Monocytes may promote myofibroblast accumulation and apoptosis in Alport renal fibrosis

  Rodgers, K. D., Rao, V., Meehan, D. T., Fager, N., Gotwals, P., Ryan, S. T., Koteliansky, V., Nemori, R. & Cosgrove, D., Apr 1 2003, In: Kidney International. 63, 4, p. 1338-1355 18 p.

  Research output: Contribution to journal › Article › peer-review

  • Myofibroblasts 100%
  • Monocytes 72%
  • Transforming Growth Factors 71%
  • Fibrosis 64%
  • Apoptosis 53%
  46 Scopus citations

• Neutralization of circulating vascular endothelial growth factor (VEGF) by anti-VEGF antibodies and soluble VEGF receptor 1 (sFlt-1) induces proteinuria

  Sugimoto, H., Hamanog, Y., Charytan, D., Cosgrove, D., Kieran, M., Sudhakar, A. & Kalluri, R., Apr 11 2003, In: Journal of Biological Chemistry. 278, 15, p. 12605-12608 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Vascular Endothelial Growth Factor Receptor-1 100%
  • Growth Factor 89%
  • Neutralization 76%
  • Proteinuria 73%
  • Vascular Endothelial Growth Factor A 65%
  481 Scopus citations
• 2002

  Determinants of vascular permeability in the kidney glomerulus

  Hamano, Y., Grunkemeyer, J. A., Sudhakar, A., Zeisberg, M., Cosgrove, D., Morello, R., Lee, B., Sugimoto, H. & Kalluri, R., Aug 23 2002, In: Journal of Biological Chemistry. 277, 34, p. 31154-31162 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Kidney Glomerulus 100%
  • Capillary Permeability 72%
  • Diaphragm 67%
  • nephrin 58%
  • Permeability 52%
  108 Scopus citations

• Localization and expression of usherin: A novel basement membrane protein defective in people with Usher's syndrome type IIa

  Bhattacharya, G., Miller, C., Kimberling, W. J., Jablonski, M. M. & Cosgrove, D., 2002, In: Hearing Research. 163, 1-2, p. 1-11 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Usher Syndromes 100%
  • Basement Membrane 64%
  • Oviducts 57%
  • Membrane Proteins 53%
  • Inner Ear 46%
  68 Scopus citations

• Strial marginal cells play a role in basement membrane homeostasis: In vitro and in vivo evidence

  Gratton, M. A., Meehan, D. T., Smyth, B. J. & Cosgrove, D., 2002, In: Hearing Research. 163, 1-2, p. 27-36 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Basement Membrane 100%
  • Homeostasis 74%
  • In Vitro Techniques 44%
  • Membrane Proteins 31%
  • laminin 8 24%
  13 Scopus citations

• Usherin expression is highly conserved in mouse and human tissues

  Pearsall, N., Bhattacharya, G., Wisecarver, J., Adams, J., Cosgrove, D. & Kimberling, W., Dec 2002, In: Hearing Research. 174, 1-2, p. 55-63 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Usher Syndromes 100%
  • Basement Membrane 25%
  • Retinitis Pigmentosa 15%
  • Fallopian Tubes 15%
  • Large Intestine 15%
  36 Scopus citations
• 2001

  Global Gene Expression Analysis Reveals a Role for the α₁ Integrin in Renal Pathogenesis

  Sampson, N. S., Ryan, S. T., Enke, D. A., Cosgrove, D., Koteliansky, V. & Gotwals, P., Sep 7 2001, In: Journal of Biological Chemistry. 276, 36, p. 34182-34188 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Hereditary Nephritis 100%
  • Integrins 96%
  • Macrophages 71%
  • Gene Expression 61%
  • Kidney 54%
  55 Scopus citations

• The laminins in the murine inner ear: Developmental transitions and expression in cochlear basement membranes

  Rodgers, K. D., Barritt, L., Miner, J. H. & Cosgrove, D., 2001, In: Hearing Research. 158, 1-2, p. 39-50 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Laminin 100%
  • Inner Ear 99%
  • Cochlea 96%
  • Basement Membrane 90%
  • Basilar Membrane 10%
  30 Scopus citations
• 2000

  Assembly of Type IV collagen. Insights from α3(IV) collagen-deficient mice

  Kalluri, R. & Cosgrove, D., Apr 28 2000, In: Journal of Biological Chemistry. 275, 17, p. 12719-12724 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Collagen Type IV 100%
  • Collagen 79%
  • Basement Membrane 32%
  • Glomerular Basement Membrane 21%
  • Thromboplastin 18%
  59 Scopus citations