Pediatrics Infectious Disease

Research Output

2020

A mosaic tetracycline resistance gene tet(S/M) detected in an MDR pneumococcal CC230 lineage that underwent capsular switching in South Africa

Global Pneumococcal Sequencing Consortium, Mar 1 2020, In : Journal of Antimicrobial Chemotherapy. 75, 3, p. 512-520 9 p.

Research output: Contribution to journalArticle

Open Access

Neonatal outcomes associated with maternal recto-vaginal colonization with extended-spectrum β-lactamase producing Enterobacteriaceae in Nigeria: a prospective, cross-sectional study

Neemann, K., Olateju, E. K., Izevbigie, N., Akaba, G., Olanipekun, G. M., Richard, J. C., Duru, C. I., Kocmich, N. J., Samson, K. K., Rezac-Elgohary, A., Anigilaje, E. A., Yunusa, T., Megafu, C. O. N., Ajose, T. O., Medugu, N., Meza, J. & Obaro, S., Apr 2020, In : Clinical Microbiology and Infection. 26, 4, p. 463-469 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

Paper-based microchip electrophoresis for point-of-care hemoglobin testing

Hasan, M. N., Fraiwan, A., An, R., Alapan, Y., Ung, R., Akkus, A., Xu, J. Z., Rezac, A. J., Kocmich, N. J., Creary, M. S., Oginni, T., Olanipekun, G. M., Hassan-Hanga, F., Jibir, B. W., Gambo, S., Verma, A. K., Bharti, P. K., Riolueang, S., Ngimhung, T., Suksangpleng, T. & 9 others, Thota, P., Werner, G., Shanmugam, R., Das, A., Viprakasit, V., Piccone, C. M., Little, J. A., Obaro, S. K. & Gurkan, U. A., Apr 7 2020, In : Analyst. 145, 7, p. 2525-2542 18 p.

Research output: Contribution to journalArticle

Open Access

Towards understanding global patterns of antimicrobial use and resistance in neonatal sepsis: Insights from the NeoAMR network

Li, G., Bielicki, J. A., Ahmed, A. S. M. N. U., Islam, M. S., Berezin, E. N., Gallacci, C. B., Guinsburg, R., Da Silva Figueiredo, C. E., Santarone Vieira, R., Silva, A. R., Teixeira, C., Turner, P., Nhan, L., Orrego, J., Pérez, P. M., Qi, L., Papaevangelou, V., Triantafyllidou, P., Iosifidis, E., Roilides, E. & 43 others, Sarafidis, K., Jinka, D. R., Nayakanti, R. R., Kumar, P., Gautam, V., Prakash, V., Seeralar, A., Murki, S., Kandraju, H., Singh, S., Kumar, A., Lewis, L., Pukayastha, J., Nangia, S., Yogesha, K. N., Chaurasia, S., Chellani, H., Obaro, S., Dramowski, A., Bekker, A., Whitelaw, A., Thomas, R., Velaphi, S. C., Ballot, D. E., Nana, T., Reubenson, G., Fredericks, J., Anugulruengkitt, S., Sirisub, A., Wong, P., Lochindarat, S., Boonkasidecha, S., Preedisripipat, K., Cressey, T. R., Paopongsawan, P., Lumbiganon, P., Pongpanut, D., Sukrakanchana, P. O., Musoke, P., Olson, L., Larsson, M., Heath, P. T. & Sharland, M., Jan 1 2020, In : Archives of Disease in Childhood. 105, 1, p. 26-31 6 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations
2019

Blood Stream Infections and Antibiotic Utilization in Pediatric Leukemia Patients with Febrile Neutropenia

Reinecke, J., Lowas, S., Snowden, J. & Neemann, K., May 1 2019, In : Journal of Pediatric Hematology/Oncology. 41, 4, p. 251-255 5 p.

Research output: Contribution to journalArticle

2 Scopus citations

CSF inflammatory markers differ in gram-positive versus gram-negative shunt infections

Skar, G. L., Synhorst, D., Beaver, M. & Snowden, J. N., Jan 9 2019, In : Journal of Neuroinflammation. 16, 1, 7.

Research output: Contribution to journalArticle

1 Scopus citations

Embracing Diversity and Inclusion in Psychiatry Leadership

Simonsen, K. A. & Shim, R. S., Sep 2019, In : Psychiatric Clinics of North America. 42, 3, p. 463-471 9 p.

Research output: Contribution to journalReview article

2 Scopus citations

Emergence of New Delhi metallo-β-lactamase (NDM-5) in Klebsiella quasipneumoniae from neonates in a Nigerian hospital

Brinkac, L. M., White, R., D'Souza, R., Nguyen, K., Obaro, S. K. & Fouts, D. E., Mar 1 2019, In : mSphere. 4, 2, e00685-18.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

Enhancing physician wellness through coaching: An occupational psychiatry tool

Schulte, E. E., Sikon, A. L., Love, L., Simonsen, K., Berry, A. & Agarwal, G., Nov 2019, In : Psychiatric Annals. 49, 11, p. 492-496 5 p.

Research output: Contribution to journalArticle

Erratum: Status of retinoids and carotenoids and associations with clinical outcomes in maternal-infant pairs in Nigeria. (Nutrients 2018, 10, 1286)

Hanson, C., Lyden, E., Anderson-Berry, A., Kocmich, N., Rezac, A., Delair, S., Furtado, J., Van Ormer, M., Izevbigie, N., Olateju, E. K., Akaba, G. O., Anigilaje, E. A., Yunusa, T. & Obaro, S., Feb 2019, In : Nutrients. 11, 2, 396.

Research output: Contribution to journalComment/debate

Open Access
Open Access
1 Scopus citations
Open Access
23 Scopus citations

Pulmonary hypertension and right ventricular function in Nigerian children with sickle cell anaemia

Peter, I. D., Asani, M. O., Abdullahi, S. U., Aliyu, I., Obaro, S. K. & Bode-Thomas, F., Aug 1 2019, In : Transactions of the Royal Society of Tropical Medicine and Hygiene. 113, 8, p. 489-496 8 p., trz038.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
5 Scopus citations

Training as an intervention to decrease medical record abstraction errors multicenter studies

Zozus, M. N., Young, L. W., Simon, A. E., Garza, M., Lawrence, L., Ounpraseuth, S. T., Bledsoe, M., Newman-Norlund, S., Jarvis, J. D., McNally, M., Harris, K. R., McCulloh, R., Aikman, R., Cox, S., Malloch, L., Walden, A., Snowden, J., Chedjieu, I. M., Wicker, C. A., Atkins, L. & 1 others, Devlin, L. A., 2019, Improving Usability, Safety and Patient Outcomes with Health Information Technology: From Research to Practice. Kuo, A. M-H., Kushniruk, A., Lau, F., Borycki, E. M., Bliss, G., Monkman, H., Roudsari, A. V., Bartle-Clar, J. A. & Courtney, K. L. (eds.). IOS Press, p. 526-539 14 p. (Studies in Health Technology and Informatics; vol. 257).

Research output: Chapter in Book/Report/Conference proceedingChapter

Updating the diagnosis of bacterial meningitis

Obaro, S., Nov 2019, In : The Lancet Infectious Diseases. 19, 11, p. 1160-1161 2 p.

Research output: Contribution to journalComment/debate

Urogenital schistosomiasis is associated with signatures of microbiome dysbiosis in Nigerian adolescents

Ajibola, O., Rowan, A. D., Ogedengbe, C. O., Mshelia, M. B., Cabral, D. J., Eze, A. A., Obaro, S. & Belenky, P., Dec 1 2019, In : Scientific reports. 9, 1, 829.

Research output: Contribution to journalArticle

5 Scopus citations
2018

A comparison of vitamin E status and associated pregnancy outcomes in maternal–infant dyads between a Nigerian and a United States population

Cave, C., Hanson, C., Schumacher, M., Lyden, E., Furtado, J., Obaro, S., Delair, S., Kocmich, N., Rezac, A., Izevbigie, N. I., Van nOrmer, M., Kamil, A., McGinn, E., Rilett, K., Elliott, E., Johnson, R., Weishaar, K., Olateju, E. K., Akaba, G. A., Anigilaje, E. A. & 2 others, Tahiru, T. & Anderson-Berry, A., Sep 14 2018, In : Nutrients. 10, 9, 1300.

Research output: Contribution to journalArticle

1 Scopus citations

Acquisition of virulence genes by a carrier strain gave rise to the ongoing epidemics of meningococcal disease in West Africa

Brynildsrud, O. B., Eldholm, V., Bohlin, J., Uadiale, K., Obaro, S. & Caugant, D. A., May 22 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 21, p. 5510-5515 6 p.

Research output: Contribution to journalArticle

23 Scopus citations

Aetiology of neonatal sepsis in Nigeria, and relevance of group b streptococcus: A systematic review

Medugu, N., Iregbu, K., Tam, P. Y. I. & Obaro, S., Jul 2018, In : PloS one. 13, 7, e0200350.

Research output: Contribution to journalReview article

5 Scopus citations

A meta-analysis of antimicrobial susceptibility profiles for pneumococcal pneumonia in sub-Saharan Africa

Iroh Tam, P. Y., Sadoh, A. E. & Obaro, S. K., Jan 2 2018, In : Paediatrics and International Child Health. 38, 1, p. 7-15 9 p.

Research output: Contribution to journalReview article

4 Scopus citations

Creating the Subspecialty Pediatrics Investigator Network

and the Steering Committee of the Subspecialty Pediatrics Investigator Network, Jan 2018, In : Journal of Pediatrics. 192, p. 3-4.e2

Research output: Contribution to journalEditorial

1 Scopus citations

Detection of Streptococcus pneumoniae from culture-negative dried blood spots by real-time PCR in Nigerian children with acute febrile illness

Iroh Tam, P. Y., Hernandez-Alvarado, N., Schleiss, M. R., Yi, A. J., Hassan-Hanga, F., Onuchukwu, C., Umoru, D. & Obaro, S. K., Sep 10 2018, In : BMC Research Notes. 11, 1, 657.

Research output: Contribution to journalArticle

2 Scopus citations

Determinants of postoperative morbidity and mortality in children managed for typhoid intestinal perforation in Kano Nigeria

Anyanwu, L. J., Mohammad, A., Abdullahi, L., Farinyaro, A. & Obaro, S., Apr 2018, In : Journal of pediatric surgery. 53, 4, p. 847-852 6 p.

Research output: Contribution to journalArticle

2 Scopus citations

Developing a Career in Pediatric Infectious Diseases

Snowden, J. & James, S. H., Dec 26 2018, In : Journal of the Pediatric Infectious Diseases Society. 7, p. S57-S59

Research output: Contribution to journalArticle

Infectious Complications of Corticosteroid Therapy

Simonsen, K. A. & Davies, H. D., 2018, Principles and Practice of Pediatric Infectious Diseases. Elsevier Inc., p. 656-658.e1

Research output: Chapter in Book/Report/Conference proceedingChapter

Invasive non-typhoidal Salmonella in sickle cell disease in Africa: Is increased gut permeability the missing link?

Lim, S. H., Methé, B. A., Knoll, B. M., Morris, A. & Obaro, S. K., Aug 30 2018, In : Journal of Translational Medicine. 16, 1, 239.

Research output: Contribution to journalComment/debate

5 Scopus citations

Policy recommendations for optimizing the infectious diseases physician-scientist workforce

Singh, U., Levy, J., Armstrong, W., Bedimo, R., Creech, C. B., Lautenbach, E., Popovich, K. J., Snowden, J. & Vyas, J. M., Aug 14 2018, In : Journal of Infectious Diseases. 218, p. S49-S54

Research output: Contribution to journalArticle

3 Scopus citations
2 Scopus citations

Reducing Serious Safety Events and Priority Hospital-Acquired Conditions in a Pediatric Hospital with the Implementation of a Patient Safety Program

Phipps, A. R., Paradis, M., Peterson, K. A., Jensen, J., Nielsen, K., Hall, M., Simonsen, K. A. & Norton, B. M., Jun 2018, In : Joint Commission Journal on Quality and Patient Safety. 44, 6, p. 334-340 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

Role of Anaerobic Blood Cultures in Neonatal Bacteremia

Messbarger, N. & Neemann, K., Aug 17 2018, In : Journal of the Pediatric Infectious Diseases Society. 7, 3, p. e65-e69

Research output: Contribution to journalArticle

2 Scopus citations

Sharing antimicrobial reports for pediatric stewardship (SHARPS): A quality improvement collaborative

SHARPS Collaborative, 2018, In : Journal of the Pediatric Infectious Diseases Society. 7, 2, p. 124-128 5 p.

Research output: Contribution to journalArticle

12 Scopus citations

Status of retinoids and carotenoids and associations with clinical outcomes in maternal-infant pairs in Nigeria

Hanson, C., Lyden, E., Anderson-Berry, A., Kocmich, N., Rezac, A., Delair, S., Furtado, J., Van Ormer, M., Izevbigie, N. I., Olateju, E. D., Adaba, G. A., Anigilaje, E. A., Tahiru, T. & Obaro, S., Sep 12 2018, In : Nutrients. 10, 9, 1286.

Research output: Contribution to journalArticle

5 Scopus citations

The institutional development award states pediatric clinical trials network: Building research capacity among the rural and medically underserved

Snowden, J., Darden, P., Palumbo, P., Saul, P. & Lee, J., Apr 1 2018, In : Current Opinion in Pediatrics. 30, 2, p. 297-302 6 p.

Research output: Contribution to journalReview article

4 Scopus citations

The phylogeography and incidence of multi-drug resistant typhoid fever in sub-Saharan Africa

Park, S. E., Pham, D. T., Boinett, C., Wong, V. K., Pak, G. D., Panzner, U., Espinoza, L. M. C., von Kalckreuth, V., Im, J., Schütt-Gerowitt, H., Crump, J. A., Breiman, R. F., Adu-Sarkodie, Y., Owusu-Dabo, E., Rakotozandrindrainy, R., Soura, A. B., Aseffa, A., Gasmelseed, N., Keddy, K. H., May, J. & 50 others, Sow, A. G., Aaby, P., Biggs, H. M., Hertz, J. T., Montgomery, J. M., Cosmas, L., Olack, B., Fields, B., Sarpong, N., Razafindrabe, T. J. L., Raminosoa, T. M., Kabore, L. P., Sampo, E., Teferi, M., Yeshitela, B., El Tayeb, M. A., Sooka, A., Meyer, C. G., Krumkamp, R., Dekker, D. M., Jaeger, A., Poppert, S., Tall, A., Niang, A., Bjerregaard-Andersen, M., Løfberg, S. V., Seo, H. J., Jeon, H. J., Deerin, J. F., Park, J., Konings, F., Ali, M., Clemens, J. D., Hughes, P., Sendagala, J. N., Vudriko, T., Downing, R., Ikumapayi, U. N., Mackenzie, G. A., Obaro, S., Argimon, S., Aanensen, D. M., Page, A., Keane, J. A., Duchene, S., Dyson, Z., Holt, K. E., Dougan, G., Marks, F. & Baker, S., Dec 1 2018, In : Nature communications. 9, 1, 5094.

Research output: Contribution to journalArticle

14 Scopus citations

Typhoid fever: Tracking the trend in Nigeria

Akinyemi, K. O., Oyefolu, A. O. B., Mutiu, W. B., Iwalokun, B. A., Ayeni, E. S., Ajose, S. O. & Obaro, S. K., 2018, In : American Journal of Tropical Medicine and Hygiene. 99, 3, p. 41-47 7 p.

Research output: Contribution to journalArticle

6 Scopus citations
2017

Childhood pneumococcal disease in Africa – A systematic review and meta-analysis of incidence, serotype distribution, and antimicrobial susceptibility

Iroh Tam, P. Y., Thielen, B. K., Obaro, S. K., Brearley, A. M., Kaizer, A. M., Chu, H. & Janoff, E. N., Apr 4 2017, In : Vaccine. 35, 15, p. 1817-1827 11 p.

Research output: Contribution to journalReview article

17 Scopus citations

Cost-effectiveness of expanding childhood routine immunization against Neisseria meningitidis serogroups C, W and Y with a quadrivalent conjugate vaccine in the African meningitis belt

Kuznik, A., Iliyasu, G., Lamorde, M., Mahmud, M., Musa, B. M., Nashabaru, I., Obaro, S., Mohammed, I. & Habib, A. G., Nov 2017, In : PloS one. 12, 11, e0188595.

Research output: Contribution to journalArticle

3 Scopus citations

Costs Associated with Ebola Preparedness at a Freestanding Pediatric Assessment Center

Simonsen, K. A., Phipps, A. R., Hall, M., Heybrock, B., Hegemann, L. & Arnow, D., Nov 1 2017, In : Infection Control and Hospital Epidemiology. 38, 11, p. 1367-1369 3 p.

Research output: Contribution to journalArticle

Development of ELISAs for diagnosis of acute typhoid fever in Nigerian children

Felgner, J., Jain, A., Nakajima, R., Liang, L., Jasinskas, A., Gotuzzo, E., Vinetz, J. M., Miyajima, F., Pirmohamed, M., Hassan-Hanga, F., Umoru, D., Jibir, B. W., Gambo, S., Olateju, K., Felgner, P. L., Obaro, S. & Davies, D. H., Jun 22 2017, In : PLoS neglected tropical diseases. 11, 6, e0005679.

Research output: Contribution to journalArticle

7 Scopus citations

Impact of a national guideline on antibiotic selection for hospitalized pneumonia

Pediatric Research in Inpatient Settings Network, Apr 2017, In : Pediatrics. 139, 4, e20163231.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations

Increased memory phenotypes of CD4+ and CD8+ t cells in children with sickle cell anaemia in Tanzania

Balandya, E., Reynolds, T., Aboud, S., Obaro, S. & Makani, J., 2017, In : Tanzania Journal of Health Research. 19, 2

Research output: Contribution to journalArticle

Painful foot nodules and rash in a teenager

Skar, G. & Simonsen, K. A., Jun 1 2017, In : Journal of the Pediatric Infectious Diseases Society. 6, 2, p. 211-213 3 p.

Research output: Contribution to journalArticle

The unrecognized burden of typhoid fever

Obaro, S. K., Iroh Tam, P. Y. & Mintz, E. D., Mar 4 2017, In : Expert Review of Vaccines. 16, 3, p. 249-260 12 p.

Research output: Contribution to journalReview article

16 Scopus citations
2016

Alteration of lymphocyte phenotype and function in sickle cell anemia: Implications for vaccine responses

Balandya, E., Reynolds, T., Obaro, S. & Makani, J., Sep 1 2016, In : American Journal of Hematology. 91, 9, p. 938-946 9 p.

Research output: Contribution to journalReview article

18 Scopus citations

An extended genotyping framework for Salmonella enterica serovar Typhi, the cause of human typhoid

Wong, V. K., Baker, S., Connor, T. R., Pickard, D., Page, A. J., Dave, J., Murphy, N., Holliman, R., Sefton, A., Millar, M., Dyson, Z. A., Dougan, G., Holt, K. E., Parkhill, J., Kingsley, R. A., Thomson, N. R., Keane, J. A., Hadfield, J., Klemm, E. J., Harris, S. R. & 63 others, Cain, A. K., Kariuki, S., Okoro, C., MacLennan, C. A., Vu Thieu, N. T., Thanh, D. P., Thompson, C., Dolecek, C., Campbell, J. I., Thwaites, G., Farrar, J., Newton, P. N., Dance, D., Turner, P., Mulholland, E. K., Hawkey, J., Edwards, D. J., Feasey, N. A., Weill, F. X., Le Hello, S., Hart, P. J., Breiman, R. F., Onsare, R. S., Watson, C. H., Edmunds, W. J., Gordon, M. A., Heyderman, R. S., Msefula, C., Jacobs, J., Lunguya, O., Chabalgoity, J. A., Kama, M., Jenkins, K., Dutta, S., Marks, F., Campos, J., Obaro, S., Keddy, K. H., Smith, A. M., Parry, C. M., Karkey, A., Dongol, S., Basnyat, B., Arjyal, A., Dufour, M., Bandaranayake, D., Toleafoa, T. N., Singh, S. P., Hatta, M., Davong, V., Isaia, L., Wijedoru, L., Crump, J. A., De Pinna, E., Nair, S., Nilles, E. J., Soeng, S., Valcanis, M., Powling, J., Dimovski, K., Hogg, G., Mather, A. E. & Amos, B., 2016, In : Nature communications. 7, 12827.

Research output: Contribution to journalArticle

44 Scopus citations

A Novel Public Library-Based Sexually Transmitted Infection Screening Program for Younger High-Risk Groups in Omaha, Nebraska, USA

Delair, S. F., Lyden, E. R., O’Keefe, A. L., Simonsen, K. A., Nared, S. R., Berthold, E. A. & Watanabe-Galloway, S., Apr 1 2016, In : Journal of Community Health. 41, 2, p. 289-295 7 p.

Research output: Contribution to journalArticle

Bacterial biofilm formation and immune evasion mechanisms

Snowden, J., Sep 22 2016, The Human Microbiota and Chronic Disease: Dysbiosis as a Cause of Human Pathology. wiley, p. 139-154 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Blood cultures for persistent fever in neutropenic pediatric patients are of low diagnostic yield

Neemann, K., Yonts, A. B., Qiu, F., Simonsen, K. A., Lowas, S. & Freifeld, A. G., Jun 10 2016, In : Journal of the Pediatric Infectious Diseases Society. 5, 2, p. 219-221 3 p., piu145.

Research output: Contribution to journalArticle

3 Scopus citations