Pediatrics Infectious Disease

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2020

A mosaic tetracycline resistance gene tet(S/M) detected in an MDR pneumococcal CC230 lineage that underwent capsular switching in South Africa

Global Pneumococcal Sequencing Consortium, Mar 1 2020, In : Journal of Antimicrobial Chemotherapy. 75, 3, p. 512-520 9 p.

Research output: Contribution to journalArticle

Open Access

Neonatal outcomes associated with maternal recto-vaginal colonization with extended-spectrum β-lactamase producing Enterobacteriaceae in Nigeria: a prospective, cross-sectional study

Neemann, K., Olateju, E. K., Izevbigie, N., Akaba, G., Olanipekun, G. M., Richard, J. C., Duru, C. I., Kocmich, N. J., Samson, K. K., Rezac-Elgohary, A., Anigilaje, E. A., Yunusa, T., Megafu, C. O. N., Ajose, T. O., Medugu, N., Meza, J. & Obaro, S., Apr 2020, In : Clinical Microbiology and Infection. 26, 4, p. 463-469 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

Paper-based microchip electrophoresis for point-of-care hemoglobin testing

Hasan, M. N., Fraiwan, A., An, R., Alapan, Y., Ung, R., Akkus, A., Xu, J. Z., Rezac, A. J., Kocmich, N. J., Creary, M. S., Oginni, T., Olanipekun, G. M., Hassan-Hanga, F., Jibir, B. W., Gambo, S., Verma, A. K., Bharti, P. K., Riolueang, S., Ngimhung, T., Suksangpleng, T. & 9 others, Thota, P., Werner, G., Shanmugam, R., Das, A., Viprakasit, V., Piccone, C. M., Little, J. A., Obaro, S. K. & Gurkan, U. A., Apr 7 2020, In : Analyst. 145, 7, p. 2525-2542 18 p.

Research output: Contribution to journalArticle

Open Access

Towards understanding global patterns of antimicrobial use and resistance in neonatal sepsis: Insights from the NeoAMR network

Li, G., Bielicki, J. A., Ahmed, A. S. M. N. U., Islam, M. S., Berezin, E. N., Gallacci, C. B., Guinsburg, R., Da Silva Figueiredo, C. E., Santarone Vieira, R., Silva, A. R., Teixeira, C., Turner, P., Nhan, L., Orrego, J., Pérez, P. M., Qi, L., Papaevangelou, V., Triantafyllidou, P., Iosifidis, E., Roilides, E. & 43 others, Sarafidis, K., Jinka, D. R., Nayakanti, R. R., Kumar, P., Gautam, V., Prakash, V., Seeralar, A., Murki, S., Kandraju, H., Singh, S., Kumar, A., Lewis, L., Pukayastha, J., Nangia, S., Yogesha, K. N., Chaurasia, S., Chellani, H., Obaro, S., Dramowski, A., Bekker, A., Whitelaw, A., Thomas, R., Velaphi, S. C., Ballot, D. E., Nana, T., Reubenson, G., Fredericks, J., Anugulruengkitt, S., Sirisub, A., Wong, P., Lochindarat, S., Boonkasidecha, S., Preedisripipat, K., Cressey, T. R., Paopongsawan, P., Lumbiganon, P., Pongpanut, D., Sukrakanchana, P. O., Musoke, P., Olson, L., Larsson, M., Heath, P. T. & Sharland, M., Jan 1 2020, In : Archives of Disease in Childhood. 105, 1, p. 26-31 6 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations
2019

Blood Stream Infections and Antibiotic Utilization in Pediatric Leukemia Patients with Febrile Neutropenia

Reinecke, J., Lowas, S., Snowden, J. & Neemann, K., May 1 2019, In : Journal of Pediatric Hematology/Oncology. 41, 4, p. 251-255 5 p.

Research output: Contribution to journalArticle

2 Scopus citations

CSF inflammatory markers differ in gram-positive versus gram-negative shunt infections

Skar, G. L., Synhorst, D., Beaver, M. & Snowden, J. N., Jan 9 2019, In : Journal of Neuroinflammation. 16, 1, 7.

Research output: Contribution to journalArticle

1 Scopus citations

Emergence of New Delhi metallo-β-lactamase (NDM-5) in Klebsiella quasipneumoniae from neonates in a Nigerian hospital

Brinkac, L. M., White, R., D'Souza, R., Nguyen, K., Obaro, S. K. & Fouts, D. E., Mar 1 2019, In : mSphere. 4, 2, e00685-18.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

Enhancing physician wellness through coaching: An occupational psychiatry tool

Schulte, E. E., Sikon, A. L., Love, L., Simonsen, K., Berry, A. & Agarwal, G., Nov 2019, In : Psychiatric Annals. 49, 11, p. 492-496 5 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
Open Access
23 Scopus citations

Pulmonary hypertension and right ventricular function in Nigerian children with sickle cell anaemia

Peter, I. D., Asani, M. O., Abdullahi, S. U., Aliyu, I., Obaro, S. K. & Bode-Thomas, F., Aug 1 2019, In : Transactions of the Royal Society of Tropical Medicine and Hygiene. 113, 8, p. 489-496 8 p., trz038.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
5 Scopus citations

Urogenital schistosomiasis is associated with signatures of microbiome dysbiosis in Nigerian adolescents

Ajibola, O., Rowan, A. D., Ogedengbe, C. O., Mshelia, M. B., Cabral, D. J., Eze, A. A., Obaro, S. & Belenky, P., Dec 1 2019, In : Scientific reports. 9, 1, 829.

Research output: Contribution to journalArticle

5 Scopus citations
2018

A comparison of vitamin E status and associated pregnancy outcomes in maternal–infant dyads between a Nigerian and a United States population

Cave, C., Hanson, C., Schumacher, M., Lyden, E., Furtado, J., Obaro, S., Delair, S., Kocmich, N., Rezac, A., Izevbigie, N. I., Van nOrmer, M., Kamil, A., McGinn, E., Rilett, K., Elliott, E., Johnson, R., Weishaar, K., Olateju, E. K., Akaba, G. A., Anigilaje, E. A. & 2 others, Tahiru, T. & Anderson-Berry, A., Sep 14 2018, In : Nutrients. 10, 9, 1300.

Research output: Contribution to journalArticle

1 Scopus citations

Acquisition of virulence genes by a carrier strain gave rise to the ongoing epidemics of meningococcal disease in West Africa

Brynildsrud, O. B., Eldholm, V., Bohlin, J., Uadiale, K., Obaro, S. & Caugant, D. A., May 22 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 21, p. 5510-5515 6 p.

Research output: Contribution to journalArticle

23 Scopus citations

Detection of Streptococcus pneumoniae from culture-negative dried blood spots by real-time PCR in Nigerian children with acute febrile illness

Iroh Tam, P. Y., Hernandez-Alvarado, N., Schleiss, M. R., Yi, A. J., Hassan-Hanga, F., Onuchukwu, C., Umoru, D. & Obaro, S. K., Sep 10 2018, In : BMC Research Notes. 11, 1, 657.

Research output: Contribution to journalArticle

2 Scopus citations

Determinants of postoperative morbidity and mortality in children managed for typhoid intestinal perforation in Kano Nigeria

Anyanwu, L. J., Mohammad, A., Abdullahi, L., Farinyaro, A. & Obaro, S., Apr 2018, In : Journal of pediatric surgery. 53, 4, p. 847-852 6 p.

Research output: Contribution to journalArticle

2 Scopus citations

Developing a Career in Pediatric Infectious Diseases

Snowden, J. & James, S. H., Dec 26 2018, In : Journal of the Pediatric Infectious Diseases Society. 7, p. S57-S59

Research output: Contribution to journalArticle

Policy recommendations for optimizing the infectious diseases physician-scientist workforce

Singh, U., Levy, J., Armstrong, W., Bedimo, R., Creech, C. B., Lautenbach, E., Popovich, K. J., Snowden, J. & Vyas, J. M., Aug 14 2018, In : Journal of Infectious Diseases. 218, p. S49-S54

Research output: Contribution to journalArticle

3 Scopus citations
2 Scopus citations

Reducing Serious Safety Events and Priority Hospital-Acquired Conditions in a Pediatric Hospital with the Implementation of a Patient Safety Program

Phipps, A. R., Paradis, M., Peterson, K. A., Jensen, J., Nielsen, K., Hall, M., Simonsen, K. A. & Norton, B. M., Jun 2018, In : Joint Commission Journal on Quality and Patient Safety. 44, 6, p. 334-340 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

Role of Anaerobic Blood Cultures in Neonatal Bacteremia

Messbarger, N. & Neemann, K., Aug 17 2018, In : Journal of the Pediatric Infectious Diseases Society. 7, 3, p. e65-e69

Research output: Contribution to journalArticle

2 Scopus citations

Sharing antimicrobial reports for pediatric stewardship (SHARPS): A quality improvement collaborative

SHARPS Collaborative, 2018, In : Journal of the Pediatric Infectious Diseases Society. 7, 2, p. 124-128 5 p.

Research output: Contribution to journalArticle

12 Scopus citations

Status of retinoids and carotenoids and associations with clinical outcomes in maternal-infant pairs in Nigeria

Hanson, C., Lyden, E., Anderson-Berry, A., Kocmich, N., Rezac, A., Delair, S., Furtado, J., Van Ormer, M., Izevbigie, N. I., Olateju, E. D., Adaba, G. A., Anigilaje, E. A., Tahiru, T. & Obaro, S., Sep 12 2018, In : Nutrients. 10, 9, 1286.

Research output: Contribution to journalArticle

5 Scopus citations

The phylogeography and incidence of multi-drug resistant typhoid fever in sub-Saharan Africa

Park, S. E., Pham, D. T., Boinett, C., Wong, V. K., Pak, G. D., Panzner, U., Espinoza, L. M. C., von Kalckreuth, V., Im, J., Schütt-Gerowitt, H., Crump, J. A., Breiman, R. F., Adu-Sarkodie, Y., Owusu-Dabo, E., Rakotozandrindrainy, R., Soura, A. B., Aseffa, A., Gasmelseed, N., Keddy, K. H., May, J. & 50 others, Sow, A. G., Aaby, P., Biggs, H. M., Hertz, J. T., Montgomery, J. M., Cosmas, L., Olack, B., Fields, B., Sarpong, N., Razafindrabe, T. J. L., Raminosoa, T. M., Kabore, L. P., Sampo, E., Teferi, M., Yeshitela, B., El Tayeb, M. A., Sooka, A., Meyer, C. G., Krumkamp, R., Dekker, D. M., Jaeger, A., Poppert, S., Tall, A., Niang, A., Bjerregaard-Andersen, M., Løfberg, S. V., Seo, H. J., Jeon, H. J., Deerin, J. F., Park, J., Konings, F., Ali, M., Clemens, J. D., Hughes, P., Sendagala, J. N., Vudriko, T., Downing, R., Ikumapayi, U. N., Mackenzie, G. A., Obaro, S., Argimon, S., Aanensen, D. M., Page, A., Keane, J. A., Duchene, S., Dyson, Z., Holt, K. E., Dougan, G., Marks, F. & Baker, S., Dec 1 2018, In : Nature communications. 9, 1, 5094.

Research output: Contribution to journalArticle

14 Scopus citations

Typhoid fever: Tracking the trend in Nigeria

Akinyemi, K. O., Oyefolu, A. O. B., Mutiu, W. B., Iwalokun, B. A., Ayeni, E. S., Ajose, S. O. & Obaro, S. K., 2018, In : American Journal of Tropical Medicine and Hygiene. 99, 3, p. 41-47 7 p.

Research output: Contribution to journalArticle

6 Scopus citations
2017

Cost-effectiveness of expanding childhood routine immunization against Neisseria meningitidis serogroups C, W and Y with a quadrivalent conjugate vaccine in the African meningitis belt

Kuznik, A., Iliyasu, G., Lamorde, M., Mahmud, M., Musa, B. M., Nashabaru, I., Obaro, S., Mohammed, I. & Habib, A. G., Nov 2017, In : PloS one. 12, 11, e0188595.

Research output: Contribution to journalArticle

3 Scopus citations

Costs Associated with Ebola Preparedness at a Freestanding Pediatric Assessment Center

Simonsen, K. A., Phipps, A. R., Hall, M., Heybrock, B., Hegemann, L. & Arnow, D., Nov 1 2017, In : Infection Control and Hospital Epidemiology. 38, 11, p. 1367-1369 3 p.

Research output: Contribution to journalArticle

Development of ELISAs for diagnosis of acute typhoid fever in Nigerian children

Felgner, J., Jain, A., Nakajima, R., Liang, L., Jasinskas, A., Gotuzzo, E., Vinetz, J. M., Miyajima, F., Pirmohamed, M., Hassan-Hanga, F., Umoru, D., Jibir, B. W., Gambo, S., Olateju, K., Felgner, P. L., Obaro, S. & Davies, D. H., Jun 22 2017, In : PLoS neglected tropical diseases. 11, 6, e0005679.

Research output: Contribution to journalArticle

7 Scopus citations

Impact of a national guideline on antibiotic selection for hospitalized pneumonia

Pediatric Research in Inpatient Settings Network, Apr 2017, In : Pediatrics. 139, 4, e20163231.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations

Increased memory phenotypes of CD4+ and CD8+ t cells in children with sickle cell anaemia in Tanzania

Balandya, E., Reynolds, T., Aboud, S., Obaro, S. & Makani, J., 2017, In : Tanzania Journal of Health Research. 19, 2

Research output: Contribution to journalArticle

Painful foot nodules and rash in a teenager

Skar, G. & Simonsen, K. A., Jun 1 2017, In : Journal of the Pediatric Infectious Diseases Society. 6, 2, p. 211-213 3 p.

Research output: Contribution to journalArticle

2016

An extended genotyping framework for Salmonella enterica serovar Typhi, the cause of human typhoid

Wong, V. K., Baker, S., Connor, T. R., Pickard, D., Page, A. J., Dave, J., Murphy, N., Holliman, R., Sefton, A., Millar, M., Dyson, Z. A., Dougan, G., Holt, K. E., Parkhill, J., Kingsley, R. A., Thomson, N. R., Keane, J. A., Hadfield, J., Klemm, E. J., Harris, S. R. & 63 others, Cain, A. K., Kariuki, S., Okoro, C., MacLennan, C. A., Vu Thieu, N. T., Thanh, D. P., Thompson, C., Dolecek, C., Campbell, J. I., Thwaites, G., Farrar, J., Newton, P. N., Dance, D., Turner, P., Mulholland, E. K., Hawkey, J., Edwards, D. J., Feasey, N. A., Weill, F. X., Le Hello, S., Hart, P. J., Breiman, R. F., Onsare, R. S., Watson, C. H., Edmunds, W. J., Gordon, M. A., Heyderman, R. S., Msefula, C., Jacobs, J., Lunguya, O., Chabalgoity, J. A., Kama, M., Jenkins, K., Dutta, S., Marks, F., Campos, J., Obaro, S., Keddy, K. H., Smith, A. M., Parry, C. M., Karkey, A., Dongol, S., Basnyat, B., Arjyal, A., Dufour, M., Bandaranayake, D., Toleafoa, T. N., Singh, S. P., Hatta, M., Davong, V., Isaia, L., Wijedoru, L., Crump, J. A., De Pinna, E., Nair, S., Nilles, E. J., Soeng, S., Valcanis, M., Powling, J., Dimovski, K., Hogg, G., Mather, A. E. & Amos, B., 2016, In : Nature communications. 7, 12827.

Research output: Contribution to journalArticle

44 Scopus citations

A Novel Public Library-Based Sexually Transmitted Infection Screening Program for Younger High-Risk Groups in Omaha, Nebraska, USA

Delair, S. F., Lyden, E. R., O’Keefe, A. L., Simonsen, K. A., Nared, S. R., Berthold, E. A. & Watanabe-Galloway, S., Apr 1 2016, In : Journal of Community Health. 41, 2, p. 289-295 7 p.

Research output: Contribution to journalArticle

Blood cultures for persistent fever in neutropenic pediatric patients are of low diagnostic yield

Neemann, K., Yonts, A. B., Qiu, F., Simonsen, K. A., Lowas, S. & Freifeld, A. G., Jun 10 2016, In : Journal of the Pediatric Infectious Diseases Society. 5, 2, p. 219-221 3 p., piu145.

Research output: Contribution to journalArticle

3 Scopus citations

Challenges in the etiology and diagnosis of acute febrile illness in children in low- and middle- income countries

Tam, P. Y. I., Obaro, S. K. & Storch, G., Jun 10 2016, In : Journal of the Pediatric Infectious Diseases Society. 5, 2, p. 190-205 16 p., piw016.

Research output: Contribution to journalArticle

17 Scopus citations

Education and communication in an interprofessional antimicrobial stewardship program

Foral, P. A., Anthone, J. M., Destache, C. J., Vivekanandan, R., Preheim, L. C., Gorby, G. L., Horne, J. M., Dobronski, L. A., Syed, J. J., Mindru, C., Ali, M. A., Ali, K. F., Neemann, K. A. & Bittner, M. J., Sep 2016, In : Journal of the American Osteopathic Association. 116, 9, p. 588-593 6 p.

Research output: Contribution to journalArticle

Open Access
12 Scopus citations

Hydroxyurea Therapy for Children With Sickle Cell Anemia in Sub-Saharan Africa: Rationale and Design of the REACH Trial

For the REACH Investigators, Jan 1 2016, In : Pediatric Blood and Cancer. 63, 1, p. 98-104 7 p.

Research output: Contribution to journalArticle

20 Scopus citations

IL-10 plays an important role in the control of inflammation but not in the bacterial burden in S. epidermidis CNS catheter infection

Gutierrez-Murgas, Y. M., Skar, G., Ramirez, D., Beaver, M. & Snowden, J., Oct 13 2016, In : Journal of Neuroinflammation. 13, 1, 271.

Research output: Contribution to journalArticle

13 Scopus citations

Molecular detection of Streptococcus pneumoniae on dried blood spots from febrile Nigerian children compared to culture

Tam, P. Y. I., Hernandez-Alvarado, N., Schleiss, M. R., Hassan-Hanga, F., Onuchukwu, C., Umoru, D. & Obaro, S. K., Mar 2016, In : PloS one. 11, 3, e0152253.

Research output: Contribution to journalArticle

9 Scopus citations

Molecular Surveillance Identifies Multiple Transmissions of Typhoid in West Africa

International Typhoid Consortium, Sep 22 2016, In : PLoS neglected tropical diseases. 10, 9, e0004781.

Research output: Contribution to journalArticle

21 Scopus citations

Serodiagnosis of acute typhoid fever in nigerian pediatric cases by detection of serum IgA and IgG against hemolysin e and Lipopolysaccharide

Davies, D. H., Jain, A., Nakajima, R., Liang, L., Jasinskis, A., Supnet, M., Felgner, P. L., Teng, A., Pablo, J., Molina, D. M. & Obaro, S. K., Aug 2016, In : American Journal of Tropical Medicine and Hygiene. 95, 2, p. 431-439 9 p.

Research output: Contribution to journalArticle

8 Scopus citations

Sickle-cell disease in Nigerian Children: Parental knowledge and laboratory results

Obaro, S. K., Daniel, Y., Lawson, J. O., Hsu, W. W., Dada, J., Essen, U., Ibrahim, K., Akindele, A., Brooks, K., Olanipekun, G., Ajose, T., Stewart, C. E. & Inusa, B. P. D., Apr 1 2016, In : Public Health Genomics. 19, 2, p. 102-107 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

The effectiveness of e-learning in pediatric medical student education

Khasawneh, R. N., Simonsen, K., Snowden, J., Higgins, J. & Beck, G., 2016, In : Medical Education Online. 21, 1, 29516.

Research output: Contribution to journalArticle

18 Scopus citations
2015
11 Scopus citations

Comparison of Opt-In Versus Opt-Out Testing for Sexually Transmitted Infections Among Inmates in a County Jail

Shaikh, R. A., Simonsen, K. A., O’Keefe, A., Earley, M., Foxall, M., Islam, K. M., Person, A., Boyle, C., Sandkovsky, U. & Margalit, R., Oct 22 2015, In : Journal of Correctional Health Care. 21, 4, p. 408-416 9 p.

Research output: Contribution to journalArticle

5 Scopus citations

Neonatal Late-Onset Sepsis Following Peripherally Inserted Central Catheter Removal: Association with Antibiotic Use and Adverse Line Events

Hoffman, M. A., Snowden, J. N., Simonsen, K. A., Nenninger, T. M., Lyden, E. R. & Anderson-Berry, A. L., Dec 1 2015, In : Journal of Infusion Nursing. 38, 2, p. 129-134 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

Phylogeographical analysis of the dominant multidrug-resistant H58 clade of Salmonella Typhi identifies inter-and intracontinental transmission events

Wong, V. K., Baker, S., Pickard, D. J., Parkhill, J., Page, A. J., Feasey, N. A., Kingsley, R. A., Thomson, N. R., Keane, J. A., Weill, F. X., Edwards, D. J., Hawkey, J., Harris, S. R., Mather, A. E., Cain, A. K., Hadfield, J., Hart, P. J., Thieu, N. T. V., Klemm, E. J., Glinos, D. A. & 54 others, Breiman, R. F., Watson, C. H., Kariuki, S., Gordon, M. A., Heyderman, R. S., Okoro, C., Jacobs, J., Lunguya, O., Edmunds, W. J., Msefula, C., Chabalgoity, J. A., Kama, M., Jenkins, K., Dutta, S., Marks, F., Campos, J., Thompson, C., Obaro, S., Maclennan, C. A., Dolecek, C., Keddy, K. H., Smith, A. M., Parry, C. M., Karkey, A., Mulholland, E. K., Campbell, J. I., Dongol, S., Basnyat, B., Dufour, M., Bandaranayake, D., Naseri, T. T., Singh, S. P., Hatta, M., Newton, P., Onsare, R. S., Isaia, L., Dance, D., Davong, V., Thwaites, G., Wijedoru, L., Crump, J. A., De Pinna, E., Nair, S., Nilles, E. J., Thanh, D. P., Turner, P., Soeng, S., Valcanis, M., Powling, J., Dimovski, K., Hogg, G., Farrar, J., Holt, K. E. & Dougan, G., May 27 2015, In : Nature Genetics. 47, 6, p. 632-639 8 p.

Research output: Contribution to journalArticle

192 Scopus citations

Rapid HIV Screening in an Urban Jail: How Testing at Exit With Linkage to Community Care Can Address Perceived Barriers

Simonsen, K. A., Shaikh, R. A., Earley, M., Foxall, M., Boyle, C., Islam, K. M., Younger, H., Sandkovsky, U., Berthold, E. & Margalit, R., Dec 1 2015, In : Journal of Primary Prevention. 36, 6, p. 427-432 6 p.

Research output: Contribution to journalArticle

3 Scopus citations