Research Output

2020
Open Access

A second case of human conjunctival infestation with thelazia gulosa and a review of T. gulosa in North America

Bradbury, R. S., Gustafson, D. T., Sapp, S. G. H., Fox, M., De Almeida, M., Boyce, M., Iwen, P., Herrera, V., Ndubuisi, M. & Bishop, H. S., Feb 1 2020, In : Clinical Infectious Diseases. 70, 3, p. 518-520 3 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Characteristic fragment ions associated with dansyl cadaverine and biotin cadaverine adducts on glutamine

Biberoglu, K., Schopfer, L. M., Tacal, O. & Lockridge, O., Jul 1 2020, In : Analytical Biochemistry. 600, 113718.

Research output: Contribution to journalArticle

Open Access

Chlorpyrifos oxon-induced isopeptide bond formation in human butyrylcholinesterase

Biberoglu, K., Tacal, O., Schopfer, L. M. & Lockridge, O., Jan 25 2020, In : Molecules. 25, 3, 533.

Research output: Contribution to journalArticle

Open Access

Clonal spread of yersinia enterocolitica 1B/O:8 in multiple zoo species

Hicks, C. L., Napier, J. E., Armstrong, D. L., Gladney, L. M., Tarr, C. L., Freeman, M. M. & Iwen, P. C., Mar 17 2020, In : Journal of Zoo and Wildlife Medicine. 51, 1, p. 170-176 7 p.

Research output: Contribution to journalArticle

First Records of Established Populations of Ixodes scapularis (Acari: Ixodidae) Collected From Three Nebraska Counties

Nielsen, L. E., Cortinas, R., Fey, P. D., Iwen, P. C. & Nielsen, D. H., May 4 2020, In : Journal of medical entomology. 57, 3, p. 939-941 3 p.

Research output: Contribution to journalArticle

Genome sequences of uncommon Shiga toxin-producing escherichia coli serotypes

Abdalhamid, B., McCutchen, E. L., Iwen, P. C., Gomes-Neto, J. C., Benson, A. K. & Hinrichs, S. H., Mar 5 2020, In : Microbiology Resource Announcements. 9, 10, e01496-19.

Research output: Contribution to journalArticle

Open Access

Genotyping and subtyping cryptosporidium to identify risk factors and transmission patterns - Nebraska, 2015-2017

Loeck, B. K., Pedati, C., Iwen, P. C., McCutchen, E., Roellig, D. M., Hlavsa, M. C., Fullerton, K., Safranek, T. & Carlson, A. V., Mar 27 2020, In : Morbidity and Mortality Weekly Report. 69, 12, p. 335-338 4 p.

Research output: Contribution to journalReview article

Open Access

Polyproline-rich peptides associated with Torpedo californica acetylcholinesterase tetramers

Toker, L., Silman, I., Zeev-Ben-Mordehai, T., Sussman, J. L., Schopfer, L. M. & Lockridge, O., Mar 1 2020, In : Chemico-Biological Interactions. 319, 109007.

Research output: Contribution to journalArticle

Open Access

Proline 285 is integral for the reactivation of organophosphate-inhibited human butyrylcholinesterase by 2-PAM*

diTargiani, R. C., Belinskaya, T., Tipparaju, P., Lockridge, O. & Saxena, A., Jun 1 2020, In : Chemico-Biological Interactions. 324, 109092.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations

Safety Considerations in the Laboratory Testing of Specimens Suspected or Known to Contain the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)

Iwen, P. C., Stiles, K. L. & Pentella, M. A., May 6 2020, In : Laboratory medicine. 51, 3, p. 239-242 4 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Tests in short supply? Try group testing

Bilder, C. R., Iwen, P. C., Abdalhamid, B., Tebbs, J. M. & McMahan, C. S., Jun 1 2020, In : Significance. 17, 3, p. 15-16 2 p.

Research output: Contribution to journalComment/debate

Open Access

Vulnerability in research: Basic ethical concepts and general approach to review

Gordon, B. G., Mar 2020, In : Ochsner Journal. 20, 1, p. 34-38 5 p.

Research output: Contribution to journalArticle

Open Access
2019

Clinical Laboratory Equipment Manufacturer Policies on Highly Hazardous Communicable Diseases

Herstein, J. J., Buehler, S. A., Le, A. B., Lowe, J. J., Iwen, P. C. & Gibbs, S. G., Jul 1 2019, In : Public Health Reports. 134, 4, p. 332-337 6 p.

Research output: Contribution to journalComment/debate

Computer-designed active human butyrylcholinesterase double mutant with a new catalytic triad

Grigorenko, B. L., Novichkova, D. A., Lushchekina, S. V., Zueva, I. V., Schopfer, L. M., Nemukhin, A. V., Varfolomeev, S. D., Lockridge, O. & Masson, P., Jun 1 2019, In : Chemico-Biological Interactions. 306, p. 138-146 9 p.

Research output: Contribution to journalArticle

1 Scopus citations

Genome Sequence of a Salmonella enterica subsp. Enterica Serovar Corvallis Strain Isolated from Human Blood

McCutchen, E. L., Galac, M., Kapsak, C., Hinrichs, S. H., Iwen, P. C. & Abdalhamid, B., 2019, In : Microbiology Resource Announcements. 8, 44, e01025-19.

Research output: Contribution to journalArticle

Open Access

Half-life of chlorpyrifos oxon and other organophosphorus esters in aqueous solution

Lockridge, O., Verdier, L. & Schopfer, L. M., Sep 25 2019, In : Chemico-Biological Interactions. 311, 108788.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
5 Scopus citations
7 Scopus citations

Strength through Structure: Defending a Structured Approach to Contraceptive Mandates in Clinical Research

Schonfeld, T. L., Brown, J. S., Amoura, N. J. & Gordon, B. G., May 1 2019, In : Ethics and Human Research. 41, 3, p. 33-35 3 p.

Research output: Contribution to journalComment/debate

The special pathogens research network: Enabling research readiness

Kraft, C. S., Kortepeter, M. G., Gordon, B., Sauer, L. M., Shenoy, E. S., Eiras, D. P., Larson, L. A., Garland, J. A., Mehta, A. K., Barrett, K., Price, C. S., Croyle, C., West, L. R., Noren, B., Kline, S., Arguinchona, C., Arguinchona, H., Grein, J. D., Connally, C., McLellan, S. & 8 others, Risi, G. F., Uyeki, T. M., Davey, R. T., Schweinle, J. E., Schwedhelm, M. M., Harvey, M., Hunt, R. C. & Kratochvil, C. J., Jan 1 2019, In : Health Security. 17, 1, p. 35-45 11 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Whole genome sequencing to characterize shiga toxin-producing Escherichia coli O26 in a public health setting

Abdalhamid, B., Mccutchen, E. L., Bouska, A. C., Weiwei, Z., Loeck, B., Hinrichs, S. H. & Iwen, P. C., Nov 1 2019, In : Journal of Infection and Public Health. 12, 6, p. 884-889 6 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
2018

Accuracy and reproducibility of the Etest to detect drugresistant Neisseria gonorrhoeae to contemporary treatment

Papp, J. R., Rowlinson, M. C., O’Connor, N. P., Wholehan, J., Razeq, J. H., Glennen, A., Ware, D., Iwen, P. C., Lee, L. V. & Hagan, C., Jan 2018, In : Journal of Medical Microbiology. 67, 1, p. 68-73 6 p., 000651.

Research output: Contribution to journalArticle

6 Scopus citations

Characterization of butyrylcholinesterase from porcine milk

Saxena, A., Belinskaya, T., Schopfer, L. M. & Lockridge, O., Aug 15 2018, In : Archives of Biochemistry and Biophysics. 652, p. 38-49 12 p.

Research output: Contribution to journalArticle

5 Scopus citations
6 Scopus citations

Cryo-EM structure of the native butyrylcholinesterase tetramer reveals a dimer of dimers stabilized by a superhelical assembly

Leung, M. R., van Bezouwen, L. S., Schopfer, L. M., Sussman, J. L., Silman, I., Lockridge, O. & Zeev-Ben-Mordehai, T., Dec 26 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 52, p. 13270-13275 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

Delipidation of plasma has minimal effects on human butyrylcholinesterase

Onder, S., Tacal, O. & Lockridge, O., Feb 15 2018, In : Frontiers in Pharmacology. 9, FEB, 117.

Research output: Contribution to journalArticle

1 Scopus citations

Esterases

Lockridge, O., Quinn, D. M. & Radić, Z., 2018, Biotransformation. Elsevier Inc., Vol. 10-15. p. 277-307 31 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations

False-negative hepatitis b surface antigen test results in a hemodialysis patient — Nebraska, 2017

Hendrickson, B., Kamili, S., Timmons, T., Iwen, P. C., Pedati, C. & Safranek, T., Mar 16 2018, In : Morbidity and Mortality Weekly Report. 67, 10, p. 311-312 2 p.

Research output: Contribution to journalComment/debate

Open Access
3 Scopus citations
1 Scopus citations

Mass Spectral Detection of Diethoxyphospho-Tyrosine Adducts on Proteins from HEK293 Cells Using Monoclonal Antibody depY for Enrichment

Onder, S., Schopfer, L. M., Tacal, O., Blake, T. A., Johnson, R. C. & Lockridge, O., Jun 18 2018, In : Chemical Research in Toxicology. 31, 6, p. 520-530 11 p.

Research output: Contribution to journalArticle

5 Scopus citations

Multistate epidemiology of histoplasmosis, united states, 2011–2014

Armstrong, P. A., Jackson, B. R., Haselow, D., Fields, V., Ireland, M., Austin, C., Signs, K., Fialkowski, V., Patel, R., Ellis, P., Iwen, P. C., Pedati, C., Gibbons-Burgener, S., Anderson, J., Dobbs, T., Davidson, S., McIntyre, M., Warren, K., Midla, J., Luong, N. & 1 others, Benedict, K., Mar 2018, In : Emerging infectious diseases. 24, 3, p. 425-431 7 p.

Research output: Contribution to journalArticle

21 Scopus citations

Nontyphoidal Salmonella enterica Nonsusceptible to Both Levofloxacin and Ceftriaxone in Nebraska, United States 2014-2015

Murphy, C. N., Fowler, R. C., Williams, A. J., Iwen, P. C. & Fey, P. D., Apr 2018, In : Foodborne pathogens and disease. 15, 4, p. 235-238 4 p.

Research output: Contribution to journalArticle

1 Scopus citations

Observed variation in N95 respirator use by nurses demonstrating isolation care

Beam, E. L., Hotchkiss, E. L., Gibbs, S. G., Hewlett, A. L., Iwen, P. C., Nuss, S. L. & Smith, P. W., May 2018, In : American Journal of Infection Control. 46, 5, p. 579-580 2 p.

Research output: Contribution to journalArticle

1 Scopus citations

Optimization of cholinesterase-based catalytic bioscavengers against organophosphorus agents

Lushchekina, S. V., Schopfer, L. M., Grigorenko, B. L., Nemukhin, A. V., Varfolomeev, S. D., Lockridge, O. & Masson, P., Mar 13 2018, In : Frontiers in Pharmacology. 9, MAR, 211.

Research output: Contribution to journalArticle

13 Scopus citations

Purification of recombinant human butyrylcholinesterase on Hupresin®

Lockridge, O., David, E., Schopfer, L. M., Masson, P., Brazzolotto, X. & Nachon, F., Dec 1 2018, In : Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 1102-1103, p. 109-115 7 p.

Research output: Contribution to journalArticle

2 Scopus citations

Toxigenic vibrio cholerae o141 in a traveler to Florida — Nebraska, 2017

Loeck, B. K. D., Roberts, A., Craney, A. R., King, S., Im, M. S., Safranek, T. J., Iwen, P. C., Carlson, A. V. & Pedati, C., Aug 3 2018, In : Morbidity and Mortality Weekly Report. 67, 30, p. 838-839 2 p.

Research output: Contribution to journalComment/debate

Open Access

U.S. High-Level Isolation Unit Clinical Laboratory Capabilities Update

Herstein, J. J., Iwen, P. C., Jelden, K. C., Biddinger, P. D., Gibbs, S. G., Le, A. B., Hewlett, A. L. & Lowe, J. J., Feb 1 2018, In : Journal of clinical microbiology. 56, 2

Research output: Contribution to journalArticle

4 Scopus citations

Use of Hupresin to Capture Red Blood Cell Acetylcholinesterase for Detection of Soman Exposure

Onder, S., Schopfer, L. M., Cashman, J. R., Tacal, O., Johnson, R. C., Blake, T. A. & Lockridge, O., Jan 2 2018, In : Analytical chemistry. 90, 1, p. 974-979 6 p.

Research output: Contribution to journalArticle

4 Scopus citations
2017

Are we there yet? Laboratory preparedness for emerging infectious diseases

Burnham, C. A. D., Kwon, J. H., Burd, E. M., Campbell, S., Iwen, P. C. & Miller, M. B., Apr 2017, In : Clinical Chemistry. 63, 4, p. 807-811 5 p.

Research output: Contribution to journalComment/debate

3 Scopus citations

Characterization of butyrylcholinesterase in bovine serum

Dafferner, A. J., Lushchekina, S., Masson, P., Xiao, G., Schopfer, L. M. & Lockridge, O., Mar 25 2017, In : Chemico-Biological Interactions. 266, p. 17-27 11 p.

Research output: Contribution to journalArticle

9 Scopus citations

Corrigendum: Endocytic recycling protein EHD1 regulates primary cilia morphogenesis and SHH signaling during neural tube development

Bhattacharyya, S., Rainey, M. A., Arya, P., Mohapatra, B. C., Mushtaq, I., Dutta, S., George, M., Storck, M. D., McComb, R. D., Muirhead, D., Todd, G. L., Gould, K., Datta, K., Waes, J. G. V., Band, V. & Band, H., Mar 23 2017, In : Scientific reports. 7, 1 p.

Research output: Contribution to journalComment/debate

Open Access

Epidemiological investigation of Candida species causing bloodstream infection in paediatric small bowel transplant recipients

Suhr, M. J., Gomes-Neto, J. C., Banjara, N., Florescu, D. F., Mercer, D. F., Iwen, P. C. & Hallen-Adams, H. E., Jun 2017, In : Mycoses. 60, 6, p. 366-374 9 p.

Research output: Contribution to journalArticle

5 Scopus citations

Evaluation of the BioFire FilmArray® GastrointestinalPanel in a Midwestern Academic Hospital

Murphy, C. N., Fowler, R. C., Iwen, P. C. & Fey, P. D., Apr 1 2017, In : European Journal of Clinical Microbiology and Infectious Diseases. 36, 4, p. 747-754 8 p.

Research output: Contribution to journalArticle

26 Scopus citations

Hupresin retains binding capacity for butyrylcholinesterase and acetylcholinesterase after sanitation with sodium hydroxide

Onder, S., David, E., Tacal, O., Schopfer, L. M. & Lockridge, O., Oct 10 2017, In : Frontiers in Pharmacology. 8, OCT, 713.

Research output: Contribution to journalArticle

8 Scopus citations

Immunopurification of Acetylcholinesterase from Red Blood Cells for Detection of Nerve Agent Exposure

Dafferner, A. J., Schopfer, L. M., Xiao, G., Cashman, J. R., Yerramalla, U., Johnson, R. C., Blake, T. A. & Lockridge, O., Oct 16 2017, In : Chemical Research in Toxicology. 30, 10, p. 1897-1910 14 p.

Research output: Contribution to journalArticle

5 Scopus citations