Research Output

(20) Identification of organophosphate-reactive proteins by tandem mass spectrometry

Li, H., Schopfer, L., Spaulding, R., Thompson, C. M. & Lockridge, O., Dec 15 2005, In : Chemico-Biological Interactions. 157-158, p. 383-384 2 p.

Research output: Contribution to journalArticle

6 Scopus citations

(29) New genetic variants of human butyrylcholinesterase in the Brazilian population

Mikami, L. R., Souza, R. L. R., Chautard-Freire-Maia, E. A. & Lockridge, O., Dec 15 2005, In : Chemico-Biological Interactions. 157-158, p. 400 1 p.

Research output: Contribution to journalArticle

(33) Structural data on the aging of diethylphosphoryl- butyrylcholinesterase

Nachon, F., Asojo, O. A., Borgstahl, G., Masson, P. & Lockridge, O., Dec 15 2005, In : Chemico-Biological Interactions. 157-158, p. 408-409 2 p.

Research output: Contribution to journalArticle

3 Scopus citations

Aberrant trafficking of NSCLC-associated EGFR mutants through the endocytic recycling pathway promotes interaction with Src

Chung, B. M., Raja, S. M., Clubb, R. J., Tu, C., George, M., Band, V. & Band, H., Nov 30 2009, In : BMC Cell Biology. 10, 84.

Research output: Contribution to journalArticle

54 Scopus citations

Abundant tissue butyrylcholinesterase and its possible function in the acetylcholinesterase knockout mouse

Li, B., Stribley, J. A., Ticu, A., Xie, W., Schopfer, L. M., Hammond, P., Brimijoin, S., Hinrichs, S. H. & Lockridge, O., 2000, In : Journal of Neurochemistry. 75, 3, p. 1320-1331 12 p.

Research output: Contribution to journalArticle

278 Scopus citations

Accuracy and reproducibility of the Etest to detect drugresistant Neisseria gonorrhoeae to contemporary treatment

Papp, J. R., Rowlinson, M. C., O’Connor, N. P., Wholehan, J., Razeq, J. H., Glennen, A., Ware, D., Iwen, P. C., Lee, L. V. & Hagan, C., Jan 2018, In : Journal of Medical Microbiology. 67, 1, p. 68-73 6 p., 000651.

Research output: Contribution to journalArticle

6 Scopus citations

Acetylcholinesterase knockouts establish central cholinergic pathways and can use butyrylcholinesterase to hydrolyze acetylcholine

Mesulam, M. M., Guillozet, A., Shaw, P., Levey, A., Duysen, E. G. & Lockridge, O., Apr 3 2002, In : Neuroscience. 110, 4, p. 627-639 13 p.

Research output: Contribution to journalArticle

452 Scopus citations

A collaborative endeavor to design cholinesterase-based catalytic scavengers against toxic organophosphorus esters

Masson, P., Nachon, F., Broomfield, C. A., Lenz, D. E., Verdier, L., Schopfer, L. M. & Lockridge, O., Sep 25 2008, In : Chemico-Biological Interactions. 175, 1-3, p. 273-280 8 p.

Research output: Contribution to journalArticle

59 Scopus citations

Acute lymphoblastic leukemia of NK-cell lineage: Responses to IL-2

Pirruccello, S. J., Bicak, M. S., Gordon, B. G., Gajl-Peczalska, K., Gnarra, D. J. & Coccia, P. F., 1989, In : Leukemia Research. 13, 9, p. 735-743 9 p.

Research output: Contribution to journalArticle

18 Scopus citations

Acute megakaryoblastic leukemia following transient myeloproliferative disorder in a patient without down syndrome

Brissette, M. D., Duval‐Arnould, B. J., Gordon, B. G. & Cotelingam, J. D., Dec 1994, In : American Journal of Hematology. 47, 4, p. 316-319 4 p.

Research output: Contribution to journalArticle

25 Scopus citations
9 Scopus citations

Adenovirus-mediated gene transfer of human butyrylcholinesterase results in persistent high-level transgene expression in vivo

Chilukuri, N., Duysen, E. G., Parikh, K., Sun, W., Doctor, B. P., Lockridge, O. & Saxena, A., Sep 25 2008, In : Chemico-Biological Interactions. 175, 1-3, p. 327-331 5 p.

Research output: Contribution to journalArticle

16 Scopus citations

Adenovirus-mediated human paraoxonase1 gene transfer to provide protection against the toxicity of the organophosphorus pesticide toxicant diazoxon

Duysen, E. G., Parikh, K., Aleti, V., Manne, V., Lockridge, O. & Chilukuri, N., Mar 2011, In : Gene Therapy. 18, 3, p. 250-257 8 p.

Research output: Contribution to journalArticle

28 Scopus citations

Adenovirus-transduced human butyrylcholinesterase in mouse blood functions as a bioscavenger of chemical warfare nerve agents

Chilukuri, N., Duysen, E. G., Parikh, K., DiTargiani, R., Doctor, B. P., Lockridge, O. & Saxena, A., Sep 2009, In : Molecular pharmacology. 76, 3, p. 612-617 6 p.

Research output: Contribution to journalArticle

12 Scopus citations

Administration of oral probiotic bacteria to pregnant women causes temporary infantile colonization

Schultz, M., Göttl, C., Young, R. J., Iwen, P. & Vanderhoof, J. A., Mar 2004, In : Journal of pediatric gastroenterology and nutrition. 38, 3, p. 293-297 5 p.

Research output: Contribution to journalArticle

121 Scopus citations
Open Access
2 Scopus citations

Affinity electrophoresis, a new way of separating usual from atypical serum cholinesterases

Lockridge, O. & La Du, B. N., 1976, In : Unknown Journal. No. 397, p. No.87

Research output: Contribution to journalArticle

A function for EHD family proteins in unidirectional retrograde dendritic transport of BACE1 and alzheimer's disease Aβ production

Buggia-Prévot, V., Fernandez, C. G., Udayar, V., Vetrivel, K. S., Elie, A., Roseman, J., Sasse, V. A., Lefkow, M., Meckler, X., Bhattacharyya, S., George, M., Kar, S., Bindokas, V. P., Parent, A. T., Rajendran, L., Band, H., Vassar, R. & Thinakaran, G., Dec 26 2013, In : Cell Reports. 5, 6, p. 1552-1563 12 p.

Research output: Contribution to journalArticle

44 Scopus citations

Aging of cholinesterases phosphylated by tabun proceeds through O-dealkylation

Carletti, E., Li, H., Li, B., Ekström, F., Nicolet, Y., Loiodice, M., Gillon, E., Froment, M. T., Lockridge, O., Schopfer, L. M., Masson, P. & Nachon, F., Nov 26 2008, In : Journal of the American Chemical Society. 130, 47, p. 16011-16020 10 p.

Research output: Contribution to journalArticle

86 Scopus citations

Aging of di-isopropyl-phosphorylated human butyrylcholinesterase

Masson, P., Fortier, P. L., Albaret, C., Froment, M. T., Bartels, C. F. & Lockridge, O., Oct 15 1997, In : Biochemical Journal. 327, 2, p. 601-607 7 p.

Research output: Contribution to journalArticle

51 Scopus citations

Aging pathways for organophosphate-inhibited human butyrylcholinesterase, including novel pathways for isomalathion, resolved by mass spectrometry

Li, H., Schopfer, L. M., Nachon, F., Froment, M. T., Masson, P. & Lockridge, O., Nov 2007, In : Toxicological Sciences. 100, 1, p. 136-145 10 p.

Research output: Contribution to journalArticle

49 Scopus citations
98 Scopus citations

A kinase inhibitor screen reveals protein kinase C-dependent endocytic recycling of ErbB2 in breast cancer cells

Bailey, T. A., Luan, H., Tom, E., Bielecki, T. A., Mohapatra, B., Ahmad, G., George, M., Kelly, D. L., Natarajan, A., Raja, S. M., Band, V. & Band, H., Oct 31 2014, In : Journal of Biological Chemistry. 289, 44, p. 30443-30458 16 p.

Research output: Contribution to journalArticle

20 Scopus citations

Albumin, a new biomarker of organophosphorus toxicant exposure, identified by mass spectrometry

Peeples, E. S., Schopfer, L. M., Duysen, E. G., Spaulding, R., Voelker, T., Thompson, C. M. & Lockridge, O., Feb 2005, In : Toxicological Sciences. 83, 2, p. 303-312 10 p.

Research output: Contribution to journalArticle

113 Scopus citations
Open Access
21 Scopus citations

Altered hippocampal muscarinic receptors in acetylcholinesterase-deficient mice

Volpicelli-Daley, L. A., Duysen, E. G., Lockridge, O. & Levey, A. I., Jun 1 2003, In : Annals of Neurology. 53, 6, p. 788-796 9 p.

Research output: Contribution to journalArticle

30 Scopus citations

Altered Striatal Function and Muscarinic Cholinergic Receptors in Acetylcholinesterase Knockout Mice

Volpicelli-Daley, L. A., Hrabovska, A., Duysen, E. G., Ferguson, S. M., Blakely, R. D., Lockridge, O. & Levey, A. I., Dec 2003, In : Molecular pharmacology. 64, 6, p. 1309-1316 8 p.

Research output: Contribution to journalArticle

51 Scopus citations

A medical health report on individuals with silent butyrylcholinesterase in the Vysya community of India

Manoharan, I., Boopathy, R., Darvesh, S. & Lockridge, O., Mar 2007, In : Clinica Chimica Acta. 378, 1-2, p. 128-135 8 p.

Research output: Contribution to journalArticle

68 Scopus citations

Amino acid sequence of the active site of human serum cholinesterase from usual, atypical, and atypical-silent genotypes

Lockridge, O. & La Du, B. N., Jun 1986, In : Biochemical Genetics. 24, 5-6, p. 485-498 14 p.

Research output: Contribution to journalArticle

16 Scopus citations

A mutation linked with autism reveals a common mechanism of endoplasmic reticulum retention for the α,β-hydrolase fold protein family

De Jaco, A., Comoletti, D., Kovarik, Z., Gaietta, G., Radić, Z., Lockridge, O., Ellisman, M. H. & Taylor, P., Apr 7 2006, In : Journal of Biological Chemistry. 281, 14, p. 9667-9676 10 p.

Research output: Contribution to journalArticle

44 Scopus citations
14 Scopus citations

An ethical framework for responding to drug shortages in pediatric oncology

Beck, J. C., Smith, L. D., Gordon, B. G. & Garrett, J. R., Jun 1 2015, In : Pediatric Blood and Cancer. 62, 6, p. 931-934 4 p.

Research output: Contribution to journalReview article

8 Scopus citations

A new rapid method for clostridium difficile DNA extraction and detection in stool: Toward point-of-care diagnostic testing

Freifeld, A. G., Simonsen, K. A., Booth, C. S., Zhao, X., Whitney, S. E., Karre, T., Iwen, P. C. & Viljoen, H. J., May 2012, In : Journal of Molecular Diagnostics. 14, 3, p. 274-279 6 p.

Research output: Contribution to journalArticle

9 Scopus citations

An improved cocaine hydrolase: The A328Y mutant of human butyrylcholinesterase is 4-fold more efficient

Xie, W., Altamirano, C. V., Bartels, C. F., Speirs, R. J., Cashman, J. R. & Lockridge, O., 1999, In : Molecular pharmacology. 55, 1, p. 83-91 9 p.

Research output: Contribution to journalArticle

114 Scopus citations

An integrated approach to laboratory testing for patients with Ebola virus disease

Iwen, P. C., Garrett, J. L., Gibbs, S. G., Lowe, J. J., Herrera, V. L., Sambol, A. R., Stiles, K., Wisecarver, J. L., Salerno, K. J., Pirruccello, S. J. & Hinrichs, S. H., Nov 1 2014, In : Laboratory medicine. 45, 4, p. e146-e151

Research output: Contribution to journalArticle

27 Scopus citations

An outbreak of avian mycobacteriosis caused by mycobacterium intracellulare in little blue penguins (Eudyptula minor)

Napier, J. E., Hinrichs, S. H., Lampen, F., Iwen, P. C., Wickert, R. S., Garrett, J. L., Aden, T. A., Restis, E., Curro, T. G., Simmons, L. G. & Armstrong, D. L., Dec 2009, In : Journal of Zoo and Wildlife Medicine. 40, 4, p. 680-686 7 p.

Research output: Contribution to journalArticle

14 Scopus citations
39 Scopus citations

Antigenic and genetic characteristics of swine-origin 2009 A(H1N1) influenza viruses circulating in humans

Garten, R. J., Davis, C. T., Russell, C. A., Shu, B., Lindstrom, S., Balish, A., Sessions, W. M., Xu, X., Skepner, E., Deyde, V., Okomo-Adhiambo, M., Gubareva, L., Barnes, J., Smith, C. B., Emery, S. L., Hillman, M. J., Rivailler, P., Smagala, J., De Graaf, M., Burke, D. F. & 39 others, Fouchier, R. A. M., Pappas, C., Alpuche-Aranda, C. M., López-Gatell, H., Olivera, H., López, I., Myers, C. A., Faix, D., Blair, P. J., Yu, C., Keene, K. M., Dotson, P. D., Boxrud, D., Sambol, A. R., Abid, S. H., St. George, K., Bannerman, T., Moore, A. L., Stringer, D. J., Blevins, P., Demmler-Harrison, G. J., Ginsberg, M., Kriner, P., Waterman, S., Smole, S., Guevara, H. F., Belongia, E. A., Clark, P. A., Beatrice, S. T., Donis, R., Katz, J., Finelli, L., Bridges, C. B., Shaw, M., Jernigan, D. B., Uyeki, T. M., Smith, D. J., Klimov, A. I. & Cox, N. J., Jul 10 2009, In : Science. 325, 5937, p. 197-201 5 p.

Research output: Contribution to journalArticle

1810 Scopus citations

Antiproliferative activity of novel imidazopyridine derivatives on castration-resistant human prostate cancer cells

Muniyan, S., Chou, Y. W., Ingersoll, M. A., Devine, A., Morris, M., Odero-Marah, V. A., Khan, S. A., Chaney, W. G., Bu, X. R. & Lin, M. F., 2014, In : Cancer Letters. 353, 1, p. 59-67 9 p.

Research output: Contribution to journalArticle

20 Scopus citations

Application of chromosomal DNA and protein targeting for the identification of Yersinia pestis

Larson, M. A., Ding, S. J., Slater, S. R., Hanway, A., Bartling, A. M., Fey, P. D., Lockridge, O., Francesconi, S. C. & Hinrichs, S. H., Jun 2013, In : Proteomics - Clinical Applications. 7, 5-6, p. 416-423 8 p.

Research output: Contribution to journalArticle

3 Scopus citations
26 Scopus citations

A pregnancy testing policy for women enrolled in clinical trials

Schonfeld, T., Schmid, K. K., Brown, J. S., Jean Amoura, N. & Gordon, B., 2013, In : IRB Ethics and Human Research. 35, 6, p. 9-15 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

Are we there yet? Laboratory preparedness for emerging infectious diseases

Burnham, C. A. D., Kwon, J. H., Burd, E. M., Campbell, S., Iwen, P. C. & Miller, M. B., Apr 2017, In : Clinical Chemistry. 63, 4, p. 807-811 5 p.

Research output: Contribution to journalComment/debate

3 Scopus citations

Argininosuccinate synthetase activity in cultured human lymphocytes

Lockridge, O., Spector, E. B. & Bloom, A. D., Apr 1977, In : Biochemical Genetics. 15, 3-4, p. 395-407 13 p.

Research output: Contribution to journalArticle

12 Scopus citations

Aromatic amino-acid residues at the active and peripheral anionic sites control the binding of E2020 (Aricept®) to cholinesterases

Saxena, A., Fedorko, J. M., Vinayaka, C. R., Medhekar, R., Radić, Z., Taylor, P., Lockridge, O. & Doctor, B. P., Nov 2003, In : European Journal of Biochemistry. 270, 22, p. 4447-4458 12 p.

Research output: Contribution to journalArticle

60 Scopus citations

Aryl acylamidase activity of human serum albumin with o-nitrotrifluoroacetanilide as the substrate

Masson, P., Froment, M. T., Darvesh, S., Schopfer, L. M. & Lockridge, O., Aug 2007, In : Journal of Enzyme Inhibition and Medicinal Chemistry. 22, 4, p. 463-469 7 p.

Research output: Contribution to journalArticle

22 Scopus citations

A second case of human conjunctival infestation with thelazia gulosa and a review of T. gulosa in North America

Bradbury, R. S., Gustafson, D. T., Sapp, S. G. H., Fox, M., De Almeida, M., Boyce, M., Iwen, P., Herrera, V., Ndubuisi, M. & Bishop, H. S., Feb 1 2020, In : Clinical Infectious Diseases. 70, 3, p. 518-520 3 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

A single amino acid substitution, Gly 117His, confers phosphotriesterase (organophosphorus acid anhydride hydrolase) activity on human butyrylcholinesterase

Lockridge, O., Blong, R. M., Masson, P., Froment, M. T., Millard, C. B. & Broomfield, C. A., Jan 28 1997, In : Biochemistry. 36, 4, p. 786-795 10 p.

Research output: Contribution to journalArticle

140 Scopus citations

Asp70 in the peripheral anionic site of human butyrylcholinesterase

Masson, P., Froment, M. T., Bartels, C. F. & Lockridge, O., 1996, In : European Journal of Biochemistry. 235, 1-2, p. 36-48 13 p.

Research output: Contribution to journalArticle

Open Access
114 Scopus citations

Assay for etoposide in human serum using solid-phase extraction and high-performance liquid chromatography with fluorescence detection

Manouilov, K. K., McGuire, T. R., Gordon, B. G. & Gwilt, P. R., Apr 10 1998, In : Journal of Chromatography B: Biomedical Applications. 707, 1-2, p. 342-346 5 p.

Research output: Contribution to journalArticle

19 Scopus citations