Research Output

2017

Immunopurification of Acetylcholinesterase from Red Blood Cells for Detection of Nerve Agent Exposure

Dafferner, A. J., Schopfer, L. M., Xiao, G., Cashman, J. R., Yerramalla, U., Johnson, R. C., Blake, T. A. & Lockridge, O., Oct 16 2017, In : Chemical Research in Toxicology. 30, 10, p. 1897-1910 14 p.

Research output: Contribution to journalArticle

5 Scopus citations

Monoclonal Antibody That Recognizes Diethoxyphosphotyrosine-Modified Proteins and Peptides Independent of Surrounding Amino Acids

Onder, S., Dafferner, A. J., Schopfer, L. M., Xiao, G., Yerramalla, U., Tacal, O., Blake, T. A., Johnson, R. C. & Lockridge, O., Dec 18 2017, In : Chemical Research in Toxicology. 30, 12, p. 2218-2228 11 p.

Research output: Contribution to journalArticle

2 Scopus citations

Mycobacterium talmoniae sp. Nov., a slowly growing mycobacterium isolated from human respiratory samples

Davidson, R. M., DeGroote, M. A., Marola, J. L., Buss, S., Jones, V., McNeil, M. R., Freifeld, A. G., Epperson, L. E., Hasan, N. A., Jackson, M., Iwen, P. C., Salfinger, M. & Strong, M., 2017, In : International Journal of Systematic and Evolutionary Microbiology. 67, 8, p. 2640-2645 6 p., 001998.

Research output: Contribution to journalArticle

3 Scopus citations
4 Scopus citations

The C5 variant of the butyrylcholinesterase tetramer includes a noncovalently bound 60 kDa lamellipodin fragment

Schopfer, L. M., Delacour, H., Masson, P., Leroy, J., Krejci, E. & Lockridge, O., Jul 2017, In : Molecules. 22, 7, 1083.

Research output: Contribution to journalArticle

9 Scopus citations
7 Scopus citations
2016

Combination Nanovaccine Demonstrates Synergistic Enhancement in Efficacy against Influenza

Ross, K., Adams, J., Loyd, H., Ahmed, S., Sambol, A., Broderick, S., Rajan, K., Kohut, M., Bronich, T., Wannemuehler, M. J., Carpenter, S., Mallapragada, S. & Narasimhan, B., Mar 14 2016, In : ACS Biomaterials Science and Engineering. 2, 3, p. 368-374 7 p.

Research output: Contribution to journalArticle

16 Scopus citations

Comparison of hospital room surface disinfection using a novel ultraviolet germicidal irradiation (UVGI) generator

Jelden, K. C., Gibbs, S. G., Smith, P. W., Hewlett, A. L., Iwen, P. C., Schmid, K. K. & Lowe, J. J., Sep 1 2016, In : Journal of occupational and environmental hygiene. 13, 9, p. 690-698 9 p.

Research output: Contribution to journalArticle

7 Scopus citations

Endocytic recycling protein EHD1 regulates primary cilia morphogenesis and SHH signaling during neural tube development

Bhattacharyya, S., Rainey, M. A., Arya, P., Dutta, S., George, M., Storck, M. D., McComb, R. D., Muirhead, D., Todd, G. L., Gould, K., Datta, K., Waes, J. G. V., Band, V. & Band, H., Feb 17 2016, In : Scientific reports. 6, 20727.

Research output: Contribution to journalArticle

22 Scopus citations

Evaluating isolation behaviors by nurses using mobile computer workstations at the bedside

Beam, E. L., Gibbs, S. G., Hewlett, A. L., Iwen, P. C., Nuss, S. L. & Smith, P. W., Oct 1 2016, In : CIN - Computers Informatics Nursing. 34, 9, p. 387-392 6 p.

Research output: Contribution to journalArticle

4 Scopus citations
9 Scopus citations
2 Scopus citations

Molecular polymorphism of human enzymes as the basis of individual sensitivity to drugs. Supercomputer-assisted modeling as a tool for analysis of structural changes and enzymatic activity of proteins

Varfolomeev, S. D., Lushchekina, S. V., Nemukhin, A. V., Kulakova, A. M., Kots, E. D., Makhaeva, G. F., Delacour, H., Lockridge, O. & Masson, P., Jun 1 2016, In : Russian Chemical Bulletin. 65, 6, p. 1592-1607 16 p.

Research output: Contribution to journalArticle

4 Scopus citations

Monoclonal antibodies to human butyrylcholinesterase reactive with butyrylcholinesterase in animal plasma

Peng, H., Brimijoin, S., Hrabovska, A., Krejci, E., Blake, T. A., Johnson, R. C., Masson, P. & Lockridge, O., Jan 5 2016, In : Chemico-Biological Interactions. 243, p. 82-90 9 p.

Research output: Contribution to journalArticle

8 Scopus citations
33 Scopus citations

Nocardia arthritidis as a cause of disseminated nocardiosis in a patient with chronic lymphocytic leukemia

Roberts, A. L., Davidson, R. M., Freifeld, A. G. & Iwen, P. C., 2016, In : IDCases. 6, p. 68-71 4 p.

Research output: Contribution to journalArticle

1 Scopus citations

Origin of polyproline-rich peptides in human butyrylcholinesterase tetramers

Peng, H., Schopfer, L. M. & Lockridge, O., Nov 25 2016, In : Chemico-Biological Interactions. 259, p. 63-69 7 p.

Research output: Contribution to journalArticle

13 Scopus citations

Possible airborne person-to-person transmission of mycobacterium bovis — Nebraska 2014–2015

Buss, B. F., Keyser-Metobo, A., Rother, J., Holtz, L., Gall, K., Jereb, J., Murphy, C. N., Iwen, P. C., Robbe-Austerman, S., Holcomb, M. A. & Infield, P., Mar 4 2016, In : Morbidity and Mortality Weekly Report. 65, 8, p. 197-201 5 p.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations

Reclassification of Wolbachia persica as Francisella persica comb. nov. and emended description of the family Francisellaceae

Larson, M. A., Nalbantoglu, U., Sayood, K., Zentz, E. B., Cer, R. Z., Iwen, P. C., Francesconi, S. C., Bishop-Lilly, K. A., Mokashi, V. P., Sjöstedt, A. & Hinrichs, S. H., Mar 2016, In : International Journal of Systematic and Evolutionary Microbiology. 66, 3, p. 1200-1205 6 p.

Research output: Contribution to journalArticle

17 Scopus citations
8 Scopus citations

U.S. ebola treatment center clinical laboratory support

Jelden, K. C., Iwen, P. C., Herstein, J. J., Biddinger, P. D., Kraft, C. S., Saiman, L., Smith, P. W., Hewlett, A. L., Gibbs, S. G. & Lowe, J. J., Apr 2016, In : Journal of clinical microbiology. 54, 4, p. 1031-1035 5 p.

Research output: Contribution to journalArticle

16 Scopus citations
2015

An ethical framework for responding to drug shortages in pediatric oncology

Beck, J. C., Smith, L. D., Gordon, B. G. & Garrett, J. R., Jun 1 2015, In : Pediatric Blood and Cancer. 62, 6, p. 931-934 4 p.

Research output: Contribution to journalReview article

8 Scopus citations

Biomarkers of Exposure to Organophosphorus Poisons: A New Motif for Covalent Binding to Tyrosine in Proteins That Have No Active Site Serine. A New Motif for Covalent Binding to Tyrosine in Proteins That Have No Active Site Serine

Lockridge, O., Schopfer, L. M. & Masson, P., Jan 21 2015, Handbook of Toxicology of Chemical Warfare Agents: Second Edition. Elsevier Inc., p. 953-965 13 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

26 Scopus citations

Clinical Challenges in Isolation Care

Beam, E., Gibbs, S. G., Hewlett, A. L., Iwen, P. C., Nuss, S. L. & Smith, P. W., Jul 11 2015, In : American Journal of Nursing. 115, 4, p. 44-49 6 p.

Research output: Contribution to journalReview article

6 Scopus citations

Comparison of 5 monoclonal antibodies for immunopurification of human butyrylcholinesterase on Dynabeads: KD values, binding pairs, and amino acid sequences

Peng, H., Brimijoin, S., Hrabovska, A., Targosova, K., Krejci, E., Blake, T. A., Johnson, R. C., Masson, P. & Lockridge, O., Oct 5 2015, In : Chemico-Biological Interactions. 240, p. 336-345 10 p.

Research output: Contribution to journalArticle

14 Scopus citations

Comparison of FilmArray and quantitative real-time reverse transcriptase PCR for detection of zaire ebolavirus from contrived and clinical specimens

Southern, T. R., Racsa, L. D., Albariño, C. G., Fey, P. D., Hinrichs, S. H., Murphy, C. N., Herrera, V. L., Sambol, A. R., Hill, C. E., Ryan, E. L., Kraft, C. S., Campbell, S., Sealy, T. K., Schuh, A., Ritchie, J. C., Lyon, G. M., Mehta, A. K., Varkey, J. B., Ribner, B. S., Brantly, K. P. & 3 others, Ströher, U., Iwen, P. C. & Burd, E. M., Sep 1 2015, In : Journal of clinical microbiology. 53, 9, p. 2956-2960 5 p.

Research output: Contribution to journalArticle

27 Scopus citations

Discrimination of candida albicans from candida dubliniensis by use of the biofire filmarray blood culture identification panel

Southern, T. R., Alelew, A. & Iwen, P. C., Jun 1 2015, In : Journal of clinical microbiology. 53, 6, p. 1999-2000 2 p.

Research output: Contribution to journalLetter

3 Scopus citations

Emergency Department Processes for the Evaluation and Management of Persons under Investigation for Ebola Virus Disease

Wadman, M. C., Schwedhelm, S. S., Watson, S., Swanhorst, J., Gibbs, S. G., Lowe, J. J., Iwen, P. C., Hayes, A. K., Needham, S., Johnson, D. W., Kalin, D. J., Zeger, W. G. & Muelleman, R. L., Sep 1 2015, In : Annals of emergency medicine. 66, 3, p. 306-314 9 p.

Research output: Contribution to journalReview article

10 Scopus citations

Hemagglutinin-based polyanhydride nanovaccines against H5N1 infuenza elicit protective virus neutralizing titers and cell-mediated immunity

Ross, K. A., Lyod, H., Wu, W., Huntimer, L., Ahmed, S., Sambol, A., Broderick, S., Flickinger, Z., Rajan, K., Bronich, T., Mallapragada, S., Wannemuehler, M. J., Carpenter, S. & Narasimhan, B., 2015, In : International journal of nanomedicine. 10, p. 229-243 15 p.

Research output: Contribution to journalArticle

27 Scopus citations
46 Scopus citations

Nebraska biocontainment unit patient discharge and environmental decontamination after Ebola care

Jelden, K. C., Gibbs, S. G., Smith, P. W., Schwedhelm, M. M., Iwen, P. C., Beam, E. L., Hayes, A. K., Marion, N., Kratochvil, C. J., Boulter, K. C., Hewlett, A. L. & Lowe, J-M. J., Mar 1 2015, In : American Journal of Infection Control. 43, 3, p. 203-205 3 p.

Research output: Contribution to journalComment/debate

15 Scopus citations

Pure human butyrylcholinesterase hydrolyzes octanoyl ghrelin to desacyl ghrelin

Schopfer, L. M., Lockridge, O. & Brimijoin, S., Dec 1 2015, In : General and Comparative Endocrinology. 224, p. 61-68 8 p.

Research output: Contribution to journalArticle

30 Scopus citations
162 Scopus citations

Smallpox vaccination of laboratory workers at US variola testing sites

Medcalf, S., Bilek, L., Hartman, T., Iwen, P. C., Leuschen, P., Miller, H., Anne, OK., Sayles, H. & Smith, P. W., Jul 23 2015, In : Emerging infectious diseases. 21, 8, p. 1437-1439 3 p.

Research output: Contribution to journalArticle

2 Scopus citations

The endocytic recycling regulatory protein EHD1 Is required for ocular lens development

Arya, P., Rainey, M. A., Bhattacharyya, S., Mohapatra, B. C., George, M., Kuracha, M. R., Storck, M. D., Band, V., Govindarajan, V. & Band, H., Dec 1 2015, In : Developmental Biology. 408, 1, p. 41-55 15 p.

Research output: Contribution to journalArticle

4 Scopus citations

The Use of TKM-100802 and Convalescent Plasma in 2 Patients with Ebola Virus Disease in the United States

Kraft, C. S., Hewlett, A. L., Koepsell, S. A., Winkler, A. M., Kratochvil, C. J., Larson, L., Varkey, J. B., Mehta, A. K., Lyon, G. M., Friedman-Moraco, R. J., Marconi, V. C., Hill, C. E., Sullivan, J. N., Johnson, D. W., Lisco, S. J., Mulligan, M. J., Uyeki, T. M., McElroy, A. K., Sealy, T., Campbell, S. & 236 others, Spiropoulou, C., Ströher, U., Crozier, I., Sacra, R., Connor, M. J., Sueblinvong, V., Franch, H. A., Smith, P. W., Ribner, B. S., Schwedhelm, S., Boulter, K., Beam, E. L., Gibbs, S., Lowe, J-M. J., Piquette, C. A., Bailey, K. L., Auxier, J., Boer, B., Hanson, T., Kaseman, J., Khan, M. S., Rhee, J. H., Wells, A., Florescu, D. F., Kalil, A. C., Rupp, M. E., Becker, V., Boeckman, B., Elder, E., Fitch, A., Flood, E., Freml, M., Frigge, R., Hanzlik, K. A., Jensen, L., Kraus, N., Molacek, D., Nevins, J., Parker, A., Peters, J., Rand, C., Roesler, K., Ryalls, K., Shradar, M., Strain, A., Sunderman, T., Sundermeier, J., Swanhorst, J., Vasa, A., Bellinghausen, J., Freihaut, F., Denny, S., Mainelli, L., Pinkney, D., Ray, D., Jevne, J., Knight, K., McCroy, D., Nadeau, R., Nightser, A., Iwen, P. C., Sambol, T., Herrera, V., Morgan, D., Trotter, S., Kerby, A., Peters, S., Southern, T., Murphy, C., Morris, R., Nuss, S., Franco, T., Ogden, C., Lazure, J., Straub, D., Hinrichs, S. H., Plumb, T. J., Florescu, M. C., Becker, J., Souchek, J., Beck, J., Heires, P., Gordon, B., Paulsen, G., Wolford, B., Petersen, J., Marion, N., Hayes, K., Tyner, K., Wilson, T., Baltes, P., Nowatzke, J., Nguyen, J., Turner, P., Boonstra, B., Jelden, K., Portrey, R., Stringfield, D., Scofield, B., Svanda, G., Horihan, J., Dahl, C., Bruno, M., Malm, K., Litz, R., Fehringer, J., Paladino, K., Opp, T., Bell, S., Adams, A., Allen, M. B., Bachman, R., Bornstein, W., Cantrell, D., Cosper, P., Feistritzer, N., Fox, J., Gartland, B., Goodman, J., Grant, S., Howard-Crow, D., Horowitz, I., Pugh, D., Ritenour, C., Ash, T., Barnes, C., Calhoun, J., Chapman, L., Daye, T., Durr, H., Evans, S., Gentry, J., Ginnane, J., Haynes, C., Hill, C., Hillis, D., Johnson, C., Loomis, J., Mamora, J., Mitchell, L., Morgan, J., Osakwe, N., Owen, J., Piazza, S., Shirley, K., Siddens, J., Silas, C., Slabach, J., Tirador, E., Todd, D., Vanairsdale, S., Brammer, N., Buchanan, J., Burd, E., Cardella, J., Eaves, B., Evans, C., Hostetler, K., Jenkins, K., Lindsey, M., Magee, J., Powers, R., Ritchie, J., Ryan, E., Bonds, S., Emamifar, A., Kuban, T., Pack, J., Rogers, S., Golston, G., Kaufman, S., Olinger, P., Olinger, S., Rengarajan, K., Thomaston, S., Beck, E., Desroches, P., Hall, C., Walker, C., Bryant, C., Hackman, B., Howard, R., Jones, M., Broughton, J., Frisle, B., Jackson, R., Lewis, J., Brown-Haithco, R., Gartin, M. L., Geralds-Washington, E., James-Jones, R., Miller, D., Stark, D., McGee, G., Jones, P., Scott-Harris, L., Cain, J., Davis, R., Johnson, T., Pickett, T., Shaw, A., Truesdale, T., Blum, J., Hill, L., Sevransky, J., Zivot, J., Walker, S., Klopman, M., Matkins, R., Meechan, C., Meechan, P., Schwock, K., Schuck, J., Stack, K., Wolf, F., Bray, B., Isakov, A., Shartar, S., Miles, W., Jamison, A., Arevalo, J., Stallings, G., Christenbury, J., Dollard, V., De Gennaro, M., Korschun, H., Seideman, N., Ziegler, T., Griffith, D. P., Dave, N., Wall, S., Hall, M., McGhee, D., Clarke, T., Vaught, R. & Peterson-Pileri, K., Aug 15 2015, In : Clinical Infectious Diseases. 61, 4, p. 496-502 7 p.

Research output: Contribution to journalArticle

101 Scopus citations
2014

A kinase inhibitor screen reveals protein kinase C-dependent endocytic recycling of ErbB2 in breast cancer cells

Bailey, T. A., Luan, H., Tom, E., Bielecki, T. A., Mohapatra, B., Ahmad, G., George, M., Kelly, D. L., Natarajan, A., Raja, S. M., Band, V. & Band, H., Oct 31 2014, In : Journal of Biological Chemistry. 289, 44, p. 30443-30458 16 p.

Research output: Contribution to journalArticle

20 Scopus citations

An integrated approach to laboratory testing for patients with Ebola virus disease

Iwen, P. C., Garrett, J. L., Gibbs, S. G., Lowe, J. J., Herrera, V. L., Sambol, A. R., Stiles, K., Wisecarver, J. L., Salerno, K. J., Pirruccello, S. J. & Hinrichs, S. H., Nov 1 2014, In : Laboratory medicine. 45, 4, p. e146-e151

Research output: Contribution to journalArticle

27 Scopus citations

Antiproliferative activity of novel imidazopyridine derivatives on castration-resistant human prostate cancer cells

Muniyan, S., Chou, Y. W., Ingersoll, M. A., Devine, A., Morris, M., Odero-Marah, V. A., Khan, S. A., Chaney, W. G., Bu, X. R. & Lin, M. F., 2014, In : Cancer Letters. 353, 1, p. 59-67 9 p.

Research output: Contribution to journalArticle

20 Scopus citations

Bacteremia caused by microbacterium binotii in a patient with sickle cell anemia

Buss, S. N., Starlin, R. & Iwen, P. C., Jan 2014, In : Journal of clinical microbiology. 52, 1, p. 379-381 3 p.

Research output: Contribution to journalArticle

6 Scopus citations

Characterization of a novel BCHE "silent" allele: Point mutation (p.Val204Asp) causes loss of activity and prolonged apnea with suxamethonium

Delacour, H., Lushchekina, S., Mabboux, I., Bousquet, A., Ceppa, F., Schopfer, L. M., Lockridge, O. & Masson, P., Jul 23 2014, In : PloS one. 9, 7, e101552.

Research output: Contribution to journalArticle

22 Scopus citations

Characterization of a novel butyrylcholinesterase point mutation (p.Ala34Val), "silent" with mivacurium

Delacour, H., Lushchekina, S., Mabboux, I., Ceppa, F., Masson, P., Schopfer, L. M. & Lockridge, O., Dec 1 2014, In : Biochemical Pharmacology. 92, 3, p. 476-483 8 p.

Research output: Contribution to journalArticle

15 Scopus citations
3 Scopus citations

Detection of cresyl phosphate-modified butyrylcholinesterase in human plasma for chemical exposure associated with aerotoxic syndrome

Schopfer, L. M., Masson, P., Lamourette, P., Simon, S. & Lockridge, O., Sep 15 2014, In : Analytical Biochemistry. 461, p. 17-26 10 p.

Research output: Contribution to journalArticle

15 Scopus citations
13 Scopus citations

Method for investigating nursing behaviors related to isolation care

Beam, E. L., Gibbs, S. G., Hewlett, A. L., Iwen, P. C., Nuss, S. L. & Smith, P. W., 2014, In : American Journal of Infection Control. 42, 11, p. 1152-1156 5 p.

Research output: Contribution to journalArticle

15 Scopus citations

No girls allowed: A sponsor's rejection of one IRB's contraception policy

Brown, J. S., Schonfeld, T. L., Amoura, N. J. & Gordon, B., Nov 1 2014, In : IRB Ethics and Human Research. 36, 6, p. 13-15 3 p.

Research output: Contribution to journalArticle

1 Scopus citations

Polyproline promotes tetramerization of recombinant human butyrylcholinesterase

Larson, M. A., Lockridge, O. & Hinrichs, S. H., Sep 1 2014, In : Biochemical Journal. 462, 2, p. 329-335 7 p.

Research output: Contribution to journalArticle

19 Scopus citations