Research Output

2013

A function for EHD family proteins in unidirectional retrograde dendritic transport of BACE1 and alzheimer's disease Aβ production

Buggia-Prévot, V., Fernandez, C. G., Udayar, V., Vetrivel, K. S., Elie, A., Roseman, J., Sasse, V. A., Lefkow, M., Meckler, X., Bhattacharyya, S., George, M., Kar, S., Bindokas, V. P., Parent, A. T., Rajendran, L., Band, H., Vassar, R. & Thinakaran, G., Dec 26 2013, In : Cell Reports. 5, 6, p. 1552-1563 12 p.

Research output: Contribution to journalArticle

44 Scopus citations

Application of chromosomal DNA and protein targeting for the identification of Yersinia pestis

Larson, M. A., Ding, S. J., Slater, S. R., Hanway, A., Bartling, A. M., Fey, P. D., Lockridge, O., Francesconi, S. C. & Hinrichs, S. H., Jun 2013, In : Proteomics - Clinical Applications. 7, 5-6, p. 416-423 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

A pregnancy testing policy for women enrolled in clinical trials

Schonfeld, T., Schmid, K. K., Brown, J. S., Jean Amoura, N. & Gordon, B., 2013, In : IRB Ethics and Human Research. 35, 6, p. 9-15 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

Clinical pharmacology of etoposide in children undergoing autologous stem cell transplantation for various solid tumours

Baheti, G., McGuire, T. R., Davda, J. P., Manouilov, K. K., Wall, D., Gwilt, P. R. & Gordon, B. B., Mar 2013, In : Xenobiotica. 43, 3, p. 276-282 7 p.

Research output: Contribution to journalArticle

2 Scopus citations
1 Scopus citations
20 Scopus citations
7 Scopus citations
32 Scopus citations

Evaluation of ambulance decontamination using gaseous chlorine dioxide

Lowe, J. J., Hewlett, A. L., Iwen, P. C., Smith, P. W. & Gibbs, S. G., Jul 2013, In : Prehospital Emergency Care. 17, 3, p. 401-408 8 p.

Research output: Contribution to journalArticle

12 Scopus citations

Human serum albumin-based design of a diflunisal prodrug

Yang, F., Ma, Z. Y., Zhang, Y., Li, G. Q., Li, M., Qin, J. K., Lockridge, O. & Liang, H., Aug 2013, In : European Journal of Pharmaceutics and Biopharmaceutics. 84, 3, p. 549-554 6 p.

Research output: Contribution to journalArticle

20 Scopus citations
11 Scopus citations

Implications of culture-independent panel-based detection of cyclospora cayetanensis

Buss, S. N., Alter, R., Iwen, P. C. & Fey, P. D., Nov 2013, In : Journal of clinical microbiology. 51, 11, p. 3909 1 p.

Research output: Contribution to journalLetter

13 Scopus citations

Inhibition pathways of the potent organophosphate CBDP with cholinesterases revealed by X-ray crystallographic snapshots and mass spectrometry

Carletti, E., Colletier, J. P., Schopfer, L. M., Santoni, G., Masson, P., Lockridge, O., Nachon, F. & Weik, M., Feb 18 2013, In : Chemical Research in Toxicology. 26, 2, p. 280-289 10 p.

Research output: Contribution to journalArticle

24 Scopus citations

Mass Spectrometry Method to Identify Aging Pathways of Sp- and Rp-Tabun Adducts on Human Butyrylcholinesterase Based on the Acid Labile P-N Bond

Jiang, W., Cashman, J. R., Nachon, F., Masson, P., Schopfer, L. M. & Lockridge, O., Apr 2013, In : Toxicological Sciences. 132, 2, p. 390-398 9 p.

Research output: Contribution to journalArticle

12 Scopus citations

Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry of titanium oxide-enriched peptides for detection of aged organophosphorus adducts on human butyrylcholinesterase

Jiang, W., Murashko, E. A., Dubrovskii, Y. A., Podolskaya, E. P., Babakov, V. N., Mikler, J., Nachon, F., Masson, P., Schopfer, L. M. & Lockridge, O., 2013, In : Analytical Biochemistry. 439, 2, p. 132-141 10 p.

Research output: Contribution to journalArticle

17 Scopus citations

Newly observed spontaneous activation of ethephon as a butyrylcholinesterase inhibitor

Liyasova, M. S., Schopfer, L. M., Kodani, S., Lantz, S. R., Casida, J. E. & Lockridge, O., Mar 18 2013, In : Chemical Research in Toxicology. 26, 3, p. 422-431 10 p.

Research output: Contribution to journalArticle

5 Scopus citations

Noncholinesterase Protein Targets of Organophosphorus Pesticides

Lockridge, O., 2013, In : Advances in Molecular Toxicology. 7, p. 179-205 27 p.

Research output: Contribution to journalArticle

1 Scopus citations

Observations on hospital room contamination testing

Smith, P. W., Gibbs, S., Sayles, H., Hewlett, A., Rupp, M. E. & Iwen, P. C., 2013, In : Healthcare Infection. 18, 1, p. 10-13 4 p.

Research output: Contribution to journalArticle

11 Scopus citations

PHOS-select iron affinity beads enrich peptides for the detection of organophosphorus adducts on albumin

Jiang, W., Dubrovskii, Y. A., Podolskaya, E. P., Murashko, E. A., Babakov, V., Nachon, F., Masson, P., Schopfer, L. M. & Lockridge, O., Dec 16 2013, In : Chemical Research in Toxicology. 26, 12, p. 1917-1925 9 p.

Research output: Contribution to journalArticle

10 Scopus citations

Polyclonal antibody to soman-tyrosine

Li, B., Duysen, E. G., Froment, M. T., Masson, P., Nachon, F., Jiang, W., Schopfer, L. M., Thiele, G. M., Klassen, L. W., Cashman, J., Williams, G. R. & Lockridge, O., Apr 15 2013, In : Chemical Research in Toxicology. 26, 4, p. 584-592 9 p.

Research output: Contribution to journalArticle

8 Scopus citations

Polyproline tetramer organizing peptides in fetal bovine serum acetylcholinesterase

Biberoglu, K., Schopfer, L. M., Saxena, A., Tacal, O. & Lockridge, O., Apr 2013, In : Biochimica et Biophysica Acta - Proteins and Proteomics. 1834, 4, p. 745-753 9 p.

Research output: Contribution to journalArticle

11 Scopus citations

Protein tyrosine adduct in humans self-poisoned by chlorpyrifos

Li, B., Eyer, P., Eddleston, M., Jiang, W., Schopfer, L. M. & Lockridge, O., Jun 15 2013, In : Toxicology and Applied Pharmacology. 269, 3, p. 215-225 11 p.

Research output: Contribution to journalArticle

17 Scopus citations
1 Scopus citations
1 Scopus citations

Strongyloides stercoralis infection in a non-endemic area

Roberts, A. L., Schneider, A. E., Young, R. L., Hinrichs, S. H. & Iwen, P. C., Sep 2013, In : Laboratory medicine. 44, 4, p. 339-343 5 p.

Research output: Contribution to journalReview article

5 Scopus citations
2012
14 Scopus citations

A new rapid method for clostridium difficile DNA extraction and detection in stool: Toward point-of-care diagnostic testing

Freifeld, A. G., Simonsen, K. A., Booth, C. S., Zhao, X., Whitney, S. E., Karre, T., Iwen, P. C. & Viljoen, H. J., May 2012, In : Journal of Molecular Diagnostics. 14, 3, p. 274-279 6 p.

Research output: Contribution to journalArticle

9 Scopus citations
26 Scopus citations

Assessment of whole-genome mapping in a well-defined outbreak of Salmonella enterica serotype saintpaul

Fey, P. D., Iwen, P. C., Zentz, E. B., Briska, A. M., Henkhaus, J. K., Bryant, K. A., Larson, M. A., Noel, R. K. & Hinrichs, S. H., Sep 2012, In : Journal of clinical microbiology. 50, 9, p. 3063-3065 3 p.

Research output: Contribution to journalArticle

8 Scopus citations
13 Scopus citations
18 Scopus citations

Human butyrylcholinesterase produced in insect cells: Huprine-based affinity purification and crystal structure

Brazzolotto, X., Wandhammer, M., Ronco, C., Trovaslet, M., Jean, L., Lockridge, O., Renard, P. Y. & Nachon, F., Aug 2012, In : FEBS Journal. 279, 16, p. 2905-2916 12 p.

Research output: Contribution to journalArticle

55 Scopus citations
6 Scopus citations

Invasive Scopulariopsis brevicaulis infection in an immunocompromised patient and review of prior cases caused by Scopulariopsis and Microascus species

Iwen, P. C., Schutte, S. D., Florescu, D. F., Noel-Hurst, R. K. & Sigler, L., Aug 2012, In : Medical Mycology. 50, 6, p. 561-569 9 p.

Research output: Contribution to journalReview article

38 Scopus citations

Loss of Dnmt3b function upregulates the tumor modifier Ment and accelerates mouse lymphomagenesis

Hlady, R. A., Novakova, S., Opavska, J., Klinkebiel, D., Peters, S. L., Bies, J., Hannah, J., Iqbal, J., Anderson, K. M., Siebler, H. M., Smith, L. M., Greiner, T. C., Bastola, D., Joshi, S., Lockridge, O., Simpson, M. A., Felsher, D. W., Wagner, K. U., Chan, W. C., Christman, J. K. & 1 others, Opavsky, R., Jan 3 2012, In : Journal of Clinical Investigation. 122, 1, p. 163-177 15 p.

Research output: Contribution to journalArticle

45 Scopus citations
11 Scopus citations

Pediococcus acidilactici endocarditis successfully treated with daptomycin

Iwen, P. C., Mindru, C., Kalil, A. C. & Florescu, D. F., Mar 2012, In : Journal of clinical microbiology. 50, 3, p. 1106-1108 3 p.

Research output: Contribution to journalArticle

6 Scopus citations

Proportional mouse model for aerosol infection by influenza

Mcdonald, R. S., Sambol, A. R., Heimbuch, B. K., Brown, T. L., Hinrichs, S. H. & Wander, J. D., Oct 2012, In : Journal of Applied Microbiology. 113, 4, p. 767-778 12 p.

Research output: Contribution to journalArticle

2 Scopus citations

The proline-rich tetramerization peptides in equine serum butyrylcholinesterase

Biberoglu, K., Schopfer, L. M., Tacal, O. & Lockridge, O., Oct 2012, In : FEBS Journal. 279, 20, p. 3844-3858 15 p.

Research output: Contribution to journalArticle

22 Scopus citations
2011

Adenovirus-mediated human paraoxonase1 gene transfer to provide protection against the toxicity of the organophosphorus pesticide toxicant diazoxon

Duysen, E. G., Parikh, K., Aleti, V., Manne, V., Lockridge, O. & Chilukuri, N., Mar 2011, In : Gene Therapy. 18, 3, p. 250-257 8 p.

Research output: Contribution to journalArticle

28 Scopus citations

Biomarkers of organophosphorus (OP) exposures in humans

Marsillach, J., Richter, R. J., Kim, J. H., Stevens, R. C., MacCoss, M. J., Tomazela, D., Suzuki, S. M., Schopfer, L. M., Lockridge, O. & Furlong, C. E., Oct 2011, In : NeuroToxicology. 32, 5, p. 656-660 5 p.

Research output: Contribution to journalArticle

42 Scopus citations

Butyrylcholinesterase: Overview, Structure, and Function

Lockridge, O., Duysen, E. G. & Masson, P., Mar 28 2011, Anticholinesterase Pesticides: Metabolism, Neurotoxicity, and Epidemiology. John Wiley and Sons, p. 25-41 17 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

9 Scopus citations

Cocrystallization studies of full-length recombinant butyrylcholinesterase (BChE) with cocaine

Asojo, O. A., Asojo, O. A., Ngamelue, M. N., Homma, K. & Lockridge, O., Apr 2011, In : Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 67, 4, p. 434-437 4 p.

Research output: Contribution to journalArticle

3 Scopus citations

Endocytic recycling proteins EHD1 and EHD2 interact with Fer-1-like-5 (Fer1L5) and mediate myoblast fusion

Posey, A. D., Pytel, P., Gardikiotes, K., Demonbreun, A. R., Rainey, M., George, M., Band, H. & McNally, E. M., Mar 4 2011, In : Journal of Biological Chemistry. 286, 9, p. 7379-7388 10 p.

Research output: Contribution to journalArticle

34 Scopus citations

Exposure to tri-o-cresyl phosphate detected in jet airplane passengers

Liyasova, M., Li, B., Schopfer, L. M., Nachon, F., Masson, P., Furlong, C. E. & Lockridge, O., Nov 1 2011, In : Toxicology and Applied Pharmacology. 256, 3, p. 337-347 11 p.

Research output: Contribution to journalArticle

44 Scopus citations

Francisella tularensis molecular typing using differential insertion sequence amplification

Larson, M. A., Fey, P. D., Bartling, A. M., Iwen, P. C., Dempsey, M. P., Francesconi, S. C. & Hinrichs, S. H., Aug 2011, In : Journal of clinical microbiology. 49, 8, p. 2786-2797 12 p.

Research output: Contribution to journalArticle

5 Scopus citations

Gene-delivered butyrylcholinesterase is prophylactic against the toxicity of chemical warfare nerve agents and organophosphorus compounds

Parikh, K., Duysen, E. G., Snow, B., Jensen, N. S., Manne, V., Lockridge, O. & Chilukuri, N., Apr 2011, In : Journal of Pharmacology and Experimental Therapeutics. 337, 1, p. 92-101 10 p.

Research output: Contribution to journalArticle

31 Scopus citations

Induction of plasma acetylcholinesterase activity in mice challenged with organophosphorus poisons

Duysen, E. G. & Lockridge, O., Sep 1 2011, In : Toxicology and Applied Pharmacology. 255, 2, p. 214-220 7 p.

Research output: Contribution to journalArticle

11 Scopus citations