Research Output

2009

Evaluation of a new West Nile Virus lateral-flow rapid IgM assay

Sambol, A. R. & Hinrichs, S. H., May 2009, In : Journal of Virological Methods. 157, 2, p. 223-226 4 p.

Research output: Contribution to journalArticle

4 Scopus citations
8 Scopus citations

Mass spectral characterization of organophosphate-labeled lysine in peptides

Grigoryan, H., Li, B., Xue, W., Grigoryan, M., Schopfer, L. M. & Lockridge, O., Nov 1 2009, In : Analytical Biochemistry. 394, 1, p. 92-100 9 p.

Research output: Contribution to journalArticle

31 Scopus citations

Mass spectrometry identifies multiple organophosphorylated sites on tubulin

Grigoryan, H., Schopfer, L. M., Peeples, E. S., Duysen, E. G., Grigoryan, M., Thompson, C. M. & Lockridge, O., Oct 15 2009, In : Toxicology and Applied Pharmacology. 240, 2, p. 149-158 10 p.

Research output: Contribution to journalArticle

34 Scopus citations

Molecular identification of Mycobacterium chimaera as a cause of infection in a patient with chronic obstructive pulmonary disease

Bills, N. D., Hinrichs, S. H., Aden, T. A., Wickert, R. S. & Iwen, P. C., Mar 2009, In : Diagnostic Microbiology and Infectious Disease. 63, 3, p. 292-295 4 p.

Research output: Contribution to journalArticle

17 Scopus citations

Nanoimages show disruption of tubulin polymerization by chlorpyrifos oxon: Implications for neurotoxicity

Grigoryan, H. & Lockridge, O., Oct 15 2009, In : Toxicology and Applied Pharmacology. 240, 2, p. 143-148 6 p.

Research output: Contribution to journalArticle

39 Scopus citations

Nerve agent analogues that produce authentic soman, sarin, tabun, and cyclohexyl methylphosphonate-modified human butyrylcholinesterase

Gilley, C., MacDonald, M., Nachon, F., Schopfer, L. M., Zhang, J., Cashman, J. R. & Lockridge, O., Oct 19 2009, In : Chemical Research in Toxicology. 22, 10, p. 1680-1688 9 p.

Research output: Contribution to journalArticle

31 Scopus citations

Overview of the Flaviviridae with an emphasis on the Japanese encephalitis group viruses

Schweitzer, B. K., Chapman, N. M. & Iwen, P. C., Aug 2009, In : Laboratory medicine. 40, 8, p. 493-499 7 p.

Research output: Contribution to journalReview article

18 Scopus citations
21 Scopus citations

The role of cooperativity with Src in oncogenic transformation mediated by non-small cell lung cancer-associated EGF receptor mutants

Chung, B. M., Dimri, M., George, M., Reddi, A. L., Chen, G., Band, V. & Band, H., Apr 23 2009, In : Oncogene. 28, 16, p. 1821-1832 12 p.

Research output: Contribution to journalArticle

44 Scopus citations
26 Scopus citations

Women and contraception in research: A pilot study

Schonfeld, T. L., Amoura, N. J., Stoner, J. A. & Gordon, B. G., Apr 1 2009, In : Journal of Women's Health. 18, 4, p. 507-512 6 p.

Research output: Contribution to journalArticle

8 Scopus citations
2008

A collaborative endeavor to design cholinesterase-based catalytic scavengers against toxic organophosphorus esters

Masson, P., Nachon, F., Broomfield, C. A., Lenz, D. E., Verdier, L., Schopfer, L. M. & Lockridge, O., Sep 25 2008, In : Chemico-Biological Interactions. 175, 1-3, p. 273-280 8 p.

Research output: Contribution to journalArticle

59 Scopus citations

Adenovirus-mediated gene transfer of human butyrylcholinesterase results in persistent high-level transgene expression in vivo

Chilukuri, N., Duysen, E. G., Parikh, K., Sun, W., Doctor, B. P., Lockridge, O. & Saxena, A., Sep 25 2008, In : Chemico-Biological Interactions. 175, 1-3, p. 327-331 5 p.

Research output: Contribution to journalArticle

16 Scopus citations

Aging of cholinesterases phosphylated by tabun proceeds through O-dealkylation

Carletti, E., Li, H., Li, B., Ekström, F., Nicolet, Y., Loiodice, M., Gillon, E., Froment, M. T., Lockridge, O., Schopfer, L. M., Masson, P. & Nachon, F., Nov 26 2008, In : Journal of the American Chemical Society. 130, 47, p. 16011-16020 10 p.

Research output: Contribution to journalArticle

86 Scopus citations

Binding and hydrolysis of soman by human serum albumin

Li, B., Nachon, F., Froment, M. T., Verdier, L., Debouzy, J. C., Brasme, B., Gillon, E., Schopfer, L. M., Lockridge, O. & Masson, P., Feb 2008, In : Chemical Research in Toxicology. 21, 2, p. 421-431 11 p.

Research output: Contribution to journalArticle

79 Scopus citations

Carbamates with differential mechanism of inhibition toward acetylcholinesterase and butyrylcholinesterase

Darvesh, S., Darvesh, K. V., McDonald, R. S., Mataija, D., Walsh, R., Mothana, S., Lockridge, O. & Martin, E., Jul 24 2008, In : Journal of Medicinal Chemistry. 51, 14, p. 4200-4212 13 p.

Research output: Contribution to journalArticle

100 Scopus citations

Choline availability and acetylcholine synthesis in the hippocampus of acetylcholinesterase-deficient mice

Hartmann, J., Kiewert, C., Duysen, E. G., Lockridge, O. & Klein, J., May 2008, In : Neurochemistry International. 52, 6, p. 972-978 7 p.

Research output: Contribution to journalArticle

25 Scopus citations

Evaluation of matrix-assisted laser desorption ionization-time-of-flight mass spectrometry in comparison to 16S rRNA gene sequencing for species identification of nonfermenting bacteria

Mellmann, A., Cloud, J., Maier, T., Keckevoet, U., Ramminger, I., Iwen, P., Dunn, J., Hall, G., Wilson, D., LaSala, P., Kostrzewa, M. & Harmsen, D., Jun 2008, In : Journal of clinical microbiology. 46, 6, p. 1946-1954 9 p.

Research output: Contribution to journalArticle

298 Scopus citations

Fast affinity purification coupled with mass spectrometry for identifying organophosphate labeled plasma butyrylcholinesterase

Li, H., Tong, L., Schopfer, L. M., Masson, P. & Lockridge, O., Sep 25 2008, In : Chemico-Biological Interactions. 175, 1-3, p. 68-72 5 p.

Research output: Contribution to journalArticle

17 Scopus citations

Five new naturally occurring mutations of the BCHE gene and frequencies of 12 butyrylcholinesterase alleles in a Brazilian population

Mikami, L. R., Wieseler, S., Souza, R. L. R., Schopfer, L. M., Nachon, F., Lockridge, O. & Chautard-Freire-Maia, E. A., Mar 2008, In : Pharmacogenetics and Genomics. 18, 3, p. 213-218 6 p.

Research output: Contribution to journalArticle

25 Scopus citations

Five tyrosines and two serines in human albumin are labeled by the organophosphorus agent FP-biotin

Ding, S. J., Carr, J., Carlson, J. E., Tong, L., Xue, W., Li, Y., Schopfer, L. M., Li, B., Nachon, F., Asojo, O., Thompson, C. M., Hinrichs, S. H., Masson, P. & Lockridge, O., Sep 2008, In : Chemical Research in Toxicology. 21, 9, p. 1787-1794 8 p.

Research output: Contribution to journalArticle

47 Scopus citations
48 Scopus citations

Increased hepatotoxicity and cardiac fibrosis in cocaine-treated butyrylcholinesterase knockout mice

Duysen, E. G., Li, B., Carlson, M., Li, Y. F., Wieseler, S., Hinrichs, S. H. & Lockridge, O., Dec 2008, In : Basic and Clinical Pharmacology and Toxicology. 103, 6, p. 514-521 8 p.

Research output: Contribution to journalArticle

24 Scopus citations

Infection control experience in a cooperative care center for transplant patients

Nusair, A., Jourdan, D., Medcalf, S., Marion, N., Iwen, P. C., Fey, P. D., Reed, E., Langnas, A. & Rupp, M. E., May 2008, In : Infection Control and Hospital Epidemiology. 29, 5, p. 424-429 6 p.

Research output: Contribution to journalArticle

11 Scopus citations

Kinetic analysis of effector modulation of butyrylcholinesterase-catalysed hydrolysis of acetanilides and homologous esters

Masson, P., Froment, M. T., Gillon, E., Nachon, F., Lockridge, O. & Schopfer, L. M., May 2008, In : FEBS Journal. 275, 10, p. 2617-2631 15 p.

Research output: Contribution to journalArticle

12 Scopus citations

Lamellipodin proline rich peptides associated with native plasma butyrylcholinesterase tetramers

Li, H., Schopfer, L. M., Masson, P. & Lockridge, O., Apr 15 2008, In : Biochemical Journal. 411, 2, p. 425-432 8 p.

Research output: Contribution to journalArticle

75 Scopus citations

Leuconostoc bacteremia in pediatric patients with short bowel syndrome

Florescu, D., Hill, L., Sudan, D. & Iwen, P. C., Nov 2008, In : Pediatric Infectious Disease Journal. 27, 11, p. 1013-1019 7 p.

Research output: Contribution to journalArticle

19 Scopus citations
55 Scopus citations

Medulloblastoma with extensive nodularity: A report of two cases

Hellbusch, L. C., Robinson, M. N., McComb, R. D., Gordon, B. G. & Meyer, R. C., Aug 2008, In : Pediatric Neurosurgery. 44, 5, p. 430-432 3 p.

Research output: Contribution to journalArticle

3 Scopus citations

Paecilomyces lilacinus infection in a liver transplant patient: Case report and review of the literature

Van Schooneveld, T., Freifeld, A., Lesiak, B., Kalil, A., Sutton, D. A. & Iwen, P. C., Apr 2008, In : Transplant Infectious Disease. 10, 2, p. 117-122 6 p.

Research output: Contribution to journalArticle

48 Scopus citations

Pharmacoeconomic analysis of microbiologic techniques for differentiating staphylococci directly from blood culture bottles

Hermsen, E. D., Shull, S. S., Klepser, D. G., Iwen, P. C., Armbrust, A., Garrett, J., Freifeld, A. G. & Rupp, M. E., Sep 2008, In : Journal of clinical microbiology. 46, 9, p. 2924-2929 6 p.

Research output: Contribution to journalArticle

14 Scopus citations

Prospective, controlled, cross-over trial of alcohol-based hand gel in critical care units

Rupp, M. E., Fitzgerald, T., Puumala, S., Anderson, J. R., Craig, R., Iwen, P. C., Jourdan, D., Keuchel, J., Marion, N., Peterson, D., Sholtz, L. & Smith, V., Jan 2008, In : Infection Control and Hospital Epidemiology. 29, 1, p. 8-15 8 p.

Research output: Contribution to journalArticle

113 Scopus citations

Pseudo-esterase activity of human albumin: Slow turnover on tyrosine 411 and stable acetylation of 82 residues including 59 lysines

Lockridge, O., Xue, W., Gaydess, A., Grigoryan, H., Ding, S. J., Schopfer, L. M., Hinrichs, S. H. & Masson, P., Aug 15 2008, In : Journal of Biological Chemistry. 283, 33, p. 22582-22590 9 p.

Research output: Contribution to journalArticle

80 Scopus citations

RFLP-WAVE analysis for rapid identification of medically important fungi

Bastola, D. R., Chandio, S. H., Iwen, P. C., Hinrichs, S. H. & Ali, H., 2008, Proceedings of the 41st Annual Hawaii International Conference on System Sciences 2008, HICSS. 4438933. (Proceedings of the Annual Hawaii International Conference on System Sciences).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Routine sampling of air for fungi does not predict risk of invasive aspergillosis in immunocompromised patients

Rupp, M. E., Iwen, P. C., Tyner, L. K., Marion, N., Reed, E. & Anderson, J. R., Mar 2008, In : Journal of Hospital Infection. 68, 3, p. 270-271 2 p.

Research output: Contribution to journalLetter

12 Scopus citations

The butyrylcholinesterase knockout mouse as a model for human butyrylcholinesterase deficiency

Li, B., Duysen, E. G., Carlson, M. & Lockridge, O., Mar 2008, In : Journal of Pharmacology and Experimental Therapeutics. 324, 3, p. 1146-1154 9 p.

Research output: Contribution to journalArticle

63 Scopus citations

The butyrylcholinesterase knockout mouse is obese on a high-fat diet

Li, B., Duysen, E. G. & Lockridge, O., Sep 25 2008, In : Chemico-Biological Interactions. 175, 1-3, p. 88-91 4 p.

Research output: Contribution to journalArticle

53 Scopus citations
12 Scopus citations
2007
9 Scopus citations

Aging pathways for organophosphate-inhibited human butyrylcholinesterase, including novel pathways for isomalathion, resolved by mass spectrometry

Li, H., Schopfer, L. M., Nachon, F., Froment, M. T., Masson, P. & Lockridge, O., Nov 2007, In : Toxicological Sciences. 100, 1, p. 136-145 10 p.

Research output: Contribution to journalArticle

49 Scopus citations

A medical health report on individuals with silent butyrylcholinesterase in the Vysya community of India

Manoharan, I., Boopathy, R., Darvesh, S. & Lockridge, O., Mar 2007, In : Clinica Chimica Acta. 378, 1-2, p. 128-135 8 p.

Research output: Contribution to journalArticle

68 Scopus citations
39 Scopus citations

Aryl acylamidase activity of human serum albumin with o-nitrotrifluoroacetanilide as the substrate

Masson, P., Froment, M. T., Darvesh, S., Schopfer, L. M. & Lockridge, O., Aug 2007, In : Journal of Enzyme Inhibition and Medicinal Chemistry. 22, 4, p. 463-469 7 p.

Research output: Contribution to journalArticle

22 Scopus citations

Brucella infections

Iwen, P., 2007, xPharm: The Comprehensive Pharmacology Reference. Elsevier Inc., p. 1-6 6 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Comparison of cognitive functions between people with silent and wild-type butyrylcholinesterase

Manoharan, I., Kuznetsova, A., Fisk, J. D., Boopathy, R., Lockridge, O. & Darvesh, S., Jul 2007, In : Journal of Neural Transmission. 114, 7, p. 939-945 7 p.

Research output: Contribution to journalArticle

19 Scopus citations

Crystallization and X-ray structure of full-length recombinant human butyrylcholinesterase

Ngamelue, M. N., Homma, K., Lockridge, O. & Asojo, O. A., Aug 10 2007, In : Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 63, 9, p. 723-727 5 p.

Research output: Contribution to journalArticle

49 Scopus citations

Excessive hippocampal acetylcholine levels in acetylcholinesterase- deficient mice are moderated by butyrylcholinesterase activity

Hartmann, J., Kiewert, C., Duysen, E. G., Lockridge, O., Greig, N. H. & Klein, J., Mar 2007, In : Journal of Neurochemistry. 100, 5, p. 1421-1429 9 p.

Research output: Contribution to journalArticle

97 Scopus citations

Expression of three naturally occurring genetic variants (G75R, E90D, I99M) of the BCHE gene of human butyrylcholinesterase

Mikami, L. R., Wieseler, S., Souza, R. L. R., Schopfer, L. M., Lockridge, O. & Chautard-Freire-Maia, E. A., Sep 2007, In : Pharmacogenetics and Genomics. 17, 9, p. 681-685 5 p.

Research output: Contribution to journalArticle

4 Scopus citations

Francisella infections

Iwen, P., 2007, xPharm: The Comprehensive Pharmacology Reference. Elsevier Inc., p. 1-7 7 p.

Research output: Chapter in Book/Report/Conference proceedingChapter