Research Output

2007

Genomic deletion marking an emerging subclone of Francisella tularensis subsp. holarctica in France and the Iberian Peninsula

Dempsey, M. P., Dobson, M., Zhang, C., Zhang, M., Lion, C., Gutiérrez-Martín, C. B., Iwen, P. C., Fey, P. D., Olson, M. E., Niemeyer, D., Francesconi, S., Crawford, R., Stanley, M., Rhodes, J., Wagner, D. M., Vogler, A. J., Birdsell, D., Keim, P., Johansson, A., Hinrichs, S. H. & 1 others, Benson, A. K., Nov 2007, In : Applied and environmental microbiology. 73, 22, p. 7465-7470 6 p.

Research output: Contribution to journalArticle

30 Scopus citations

Hydrolysis of oxo- and thio-esters by human butyrylcholinesterase

Masson, P., Froment, M. T., Gillon, E., Nachon, F., Lockridge, O. & Schopfer, L. M., Jan 2007, In : Biochimica et Biophysica Acta - Proteins and Proteomics. 1774, 1, p. 16-34 19 p.

Research output: Contribution to journalArticle

16 Scopus citations
88 Scopus citations

Molecular analysis of Francisella tularensis subspecies tularensis and holarctica

Fey, P. D., Dempsey, M. M. P., Olson, M. E., Chrustowski, M. S., Engle, J. L., Jay, J. J., Dobson, M. E., Kalasinsky, K. S., Shea, A. A., Iwen, P. C., Wickert, R. C., Francesconi, S. C., Crawford, R. M. & Hinrichs, S. H., Dec 2007, In : American journal of clinical pathology. 128, 6, p. 926-935 10 p.

Research output: Contribution to journalArticle

13 Scopus citations

Money matters

Schonfeld, T., Gordon, B., Amoura, J. & Brown, J. S., Feb 2007, In : American Journal of Bioethics. 7, 2, p. 86-88 3 p.

Research output: Contribution to journalComment/debate

1 Scopus citations

Mucor circinelloides was identified by molecular methods as a cause of primary cutaneous zygomycosis

Iwen, P. C., Sigler, L., Noel, R. K. & Freifeld, A. G., Feb 2007, In : Journal of clinical microbiology. 45, 2, p. 636-639 4 p.

Research output: Contribution to journalArticle

30 Scopus citations

Neuropathological and immunochemical studies of brain parenchyma in acetylcholinesterase knockout mice: Implications in Alzheimer's disease

Rice, S. G., Nowak, L., Duysen, E. G., Lockridge, O., Lahiri, D. K. & Reyes, P. F., 2007, In : Journal of Alzheimer's Disease. 11, 4, p. 481-489 9 p.

Research output: Contribution to journalArticle

8 Scopus citations

Outbreak of bloodstream infection temporally associated with the use of an intravascular needleless valve

Rupp, M. E., Sholtz, L. A., Jourdan, D. R., Marion, N. D., Tyner, L. K., Fey, P. D., Iwen, P. C. & Anderson, J. R., Jun 1 2007, In : Clinical Infectious Diseases. 44, 11, p. 1408-1414 7 p.

Research output: Contribution to journalArticle

83 Scopus citations
9 Scopus citations
68 Scopus citations

Shared as well as distinct roles of EHD proteins revealed by biochemical and functional comparisons in mammalian cells and C. elegans

George, M., Ying, G. G., Rainey, M. A., Solomon, A., Parikh, P. T., Gao, Q., Band, V. & Band, H., 2007, In : BMC Cell Biology. 8, 3.

Research output: Contribution to journalArticle

80 Scopus citations
2006

A mutation linked with autism reveals a common mechanism of endoplasmic reticulum retention for the α,β-hydrolase fold protein family

De Jaco, A., Comoletti, D., Kovarik, Z., Gaietta, G., Radić, Z., Lockridge, O., Ellisman, M. H. & Taylor, P., Apr 7 2006, In : Journal of Biological Chemistry. 281, 14, p. 9667-9676 10 p.

Research output: Contribution to journalArticle

44 Scopus citations

Biomarkers of organophosphate exposure

Lockridge, O. & Schopfer, L. M., 2006, Toxicology of Organophosphate & Carbamate Compounds. Elsevier Inc., p. 703-711 9 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

18 Scopus citations

Designing a biocontainment unit to care for patients with serious communicable diseases: A consensus statement

Smith, P. W., Anderson, A. O., Christopher, G. W., Cieslak, T. J., Devreede, G. J., Fosdick, G. A., Greiner, C. B., Hauser, J. M., Hinrichs, S. H., Huebner, K. D., Iwen, P. C., Jourdan, D. R., Kortepeter, M. G., Landon, V. P., Lenaghan, P. A., Leopold, R. E., Marklund, L. A., Martin, J. W., Medcalf, S. J., Mussack, R. J. & 12 others, Neal, R. H., Ribner, B. S., Richmond, J. Y., Rogge, C., Roselle, G. A., Rupp, M. E., Sambol, A. R., Schaefer, J. E., Sibley, J., Streifel, A. J., Von Essen, S. G. & Warfield, K. L., 2006, In : Biosecurity and Bioterrorism. 4, 4, p. 351-365 15 p.

Research output: Contribution to journalArticle

63 Scopus citations

Designing an emergency response system for electronic laboratory diagnostics consultation

Fruhling, A., Sambol, A., Hinrichs, S. & Devreede, G. J., 2006, Proceedings of the 39th Annual Hawaii International Conference on System Sciences, HICSS'06. p. 37a 1579365. (Proceedings of the Annual Hawaii International Conference on System Sciences; vol. 2).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

5 Scopus citations

First report of Mycobacterium nebraskense as a cause of human infection

Iwen, P. C., Tarantolo, S. R., Mohamed, A. M. & Hinrichs, S. H., Dec 2006, In : Diagnostic Microbiology and Infectious Disease. 56, 4, p. 451-453 3 p.

Research output: Contribution to journalArticle

3 Scopus citations

Gene transfer of acetylcholinesterase protects the knockout mouse from the toxicity of DFP

Li, B., Duysen, E. G. & Lockridge, O., Sep 2006, In : Journal of Molecular Neuroscience. 30, 1-2, p. 79-80 2 p.

Research output: Contribution to journalArticle

2 Scopus citations
22 Scopus citations

Markers of organophosphate exposure in human serum

Wieseler, S., Schopfer, L. & Lockridge, O., Sep 2006, In : Journal of Molecular Neuroscience. 30, 1-2, p. 93-94 2 p.

Research output: Contribution to journalArticle

6 Scopus citations

Mutant of Bungarus fasciatus acetylcholinesterase with low affinity and low hydrolase activity toward organophosphorus esters

Poyot, T., Nachon, F., Froment, M. T., Loiodice, M., Wieseler, S., Schopfer, L. M., Lockridge, O. & Masson, P., Sep 2006, In : Biochimica et Biophysica Acta - Proteins and Proteomics. 1764, 9, p. 1470-1478 9 p.

Research output: Contribution to journalArticle

23 Scopus citations

Naturally occurring mutation Leu307Pro of human butyrylcholinesterase in the Vysya community of India

Manoharan, I., Wieseler, S., Layer, P. G., Lockridge, O. & Boopathy, R., Jul 2006, In : Pharmacogenetics and Genomics. 16, 7, p. 461-468 8 p.

Research output: Contribution to journalArticle

35 Scopus citations

Phase II study of clofarabine in pediatric patients with refractory or relapsed acute lymphoblastic leukemia

Jeha, S., Gaynon, P. S., Razzouk, B. I., Franklin, J., Kadota, R., Shen, V., Luchtman-Jones, L., Rytting, M., Bomgaars, L. R., Rheingold, S., Ritchey, K., Albano, E., Arceci, R. J., Goldman, S., Griffin, T., Altman, A., Gordon, B., Steinherz, L., Weitman, S. & Steinherz, P., Apr 20 2006, In : Journal of Clinical Oncology. 24, 12, p. 1917-1923 7 p.

Research output: Contribution to journalArticle

188 Scopus citations

Phenotype comparison of three acetylcholinesterase knockout strains

Duysen, E. G. & Lockridge, O., Sep 2006, In : Journal of Molecular Neuroscience. 30, 1-2, p. 91-92 2 p.

Research output: Contribution to journalArticle

15 Scopus citations

Production of the butyrylcholinesterase knockout mouse

Li, B., Duysen, E. G., Saunders, T. L. & Lockridge, O., Sep 2006, In : Journal of Molecular Neuroscience. 30, 1-2, p. 193-195 3 p.

Research output: Contribution to journalArticle

29 Scopus citations

Protection from the toxicity of diisopropylfluorophosphate by adeno-associated virus expressing acetylcholinesterase

Li, B., Duysen, E. G., Poluektova, L. Y., Murrin, L. C. & Lockridge, O., Jul 15 2006, In : Toxicology and Applied Pharmacology. 214, 2, p. 152-165 14 p.

Research output: Contribution to journalArticle

12 Scopus citations

Towards an evaluation of a microbiology laboratory system

Johnson, N., Fruhling, A., Sambol, A. & Hinrichs, S., 2006, Association for Information Systems - 12th Americas Conference On Information Systems, AMCIS 2006. p. 2692-2696 5 p. (Association for Information Systems - 12th Americas Conference On Information Systems, AMCIS 2006; vol. 5).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

"You may have already won...": An examination of the use of lottery payments in research

Brown, J. S., Schonfeld, T. L. & Gordon, B. C., Jan 2006, In : IRB Ethics and Human Research. 28, 1, p. 12-16 5 p.

Research output: Contribution to journalArticle

6 Scopus citations
2005

(20) Identification of organophosphate-reactive proteins by tandem mass spectrometry

Li, H., Schopfer, L., Spaulding, R., Thompson, C. M. & Lockridge, O., Dec 15 2005, In : Chemico-Biological Interactions. 157-158, p. 383-384 2 p.

Research output: Contribution to journalArticle

6 Scopus citations

(29) New genetic variants of human butyrylcholinesterase in the Brazilian population

Mikami, L. R., Souza, R. L. R., Chautard-Freire-Maia, E. A. & Lockridge, O., Dec 15 2005, In : Chemico-Biological Interactions. 157-158, p. 400 1 p.

Research output: Contribution to journalArticle

(33) Structural data on the aging of diethylphosphoryl- butyrylcholinesterase

Nachon, F., Asojo, O. A., Borgstahl, G., Masson, P. & Lockridge, O., Dec 15 2005, In : Chemico-Biological Interactions. 157-158, p. 408-409 2 p.

Research output: Contribution to journalArticle

3 Scopus citations

Albumin, a new biomarker of organophosphorus toxicant exposure, identified by mass spectrometry

Peeples, E. S., Schopfer, L. M., Duysen, E. G., Spaulding, R., Voelker, T., Thompson, C. M. & Lockridge, O., Feb 2005, In : Toxicological Sciences. 83, 2, p. 303-312 10 p.

Research output: Contribution to journalArticle

113 Scopus citations

Butyrylcholinesterase, paraoxonase, and albumin esterase, but not carboxylesterase, are present in human plasma

Li, B., Sedlacek, M., Manoharan, I., Boopathy, R., Duysen, E. G., Masson, P. & Lockridge, O., Nov 25 2005, In : Biochemical Pharmacology. 70, 11, p. 1673-1684 12 p.

Research output: Contribution to journalArticle

371 Scopus citations

Characteristic mass spectral fragments of the organophosphorus agent FP-biotin and FP-biotinylated peptides from trypsin and bovine albumin (Tyr410)

Schopfer, L. M., Champion, M. M., Tamblyn, N., Thompson, C. M. & Lockridge, O., Oct 1 2005, In : Analytical Biochemistry. 345, 1, p. 122-132 11 p.

Research output: Contribution to journalArticle

33 Scopus citations
22 Scopus citations

Contraception in research: A policy suggestion

Schonfeld, T. L. & Gordon, B. G., 2005, In : IRB Ethics and Human Research. 27, 2, p. 15-20 6 p.

Research output: Contribution to journalArticle

11 Scopus citations

Delivery of human acetylcholinesterase by adeno-associated virus to the acetylcholinesterase knockout mouse

Hrabovska, A., Duysen, E. G., Sanders, J. D., Murrin, L. C. & Lockridge, O., Dec 15 2005, In : Chemico-Biological Interactions. 157-158, p. 71-78 8 p.

Research output: Contribution to journalArticle

11 Scopus citations

Histoplasmosis in solid organ transplant recipients at a large Midwestern university transplant center

Freifeld, A. G., Iwen, P. C., Lesiak, B. L., Gilroy, R. K., Stevens, R. B. & Kalil, A. C., Sep 2005, In : Transplant Infectious Disease. 7, 3-4, p. 109-115 7 p.

Research output: Contribution to journalArticle

106 Scopus citations

Hysteresis of butyrylcholinesterase in the approach to steady-state kinetics

Masson, P., Schopfer, L. M., Froment, M. T., Debouzy, J. C., Nachon, F., Gillon, E., Lockridge, O., Hrabovska, A. & Goldstein, B. N., Dec 15 2005, In : Chemico-Biological Interactions. 157-158, p. 143-152 10 p.

Research output: Contribution to journalArticle

21 Scopus citations

Identification and first report of Inonotus (Phellinus) tropicalis as an etiologic agent in a patient with chronic granulomatous disease

Sutton, D. A., Thompson, E. H., Rinaldi, M. G., Iwen, P. C., Nakasone, K. K., Jung, H. S., Rosenblatt, H. M. & Paul, M. E., Feb 2005, In : Journal of clinical microbiology. 43, 2, p. 982-987 6 p.

Research output: Contribution to journalArticle

35 Scopus citations

Identification of pathogenic fungi using computational and molecular biological approaches

Chandio, S. H., Bastola, D. R., Iwen, P. C. & Hinrichs, S. H., 2005, 2005 IEEE International Conference on Electro Information Technology. 1627000. (2005 IEEE International Conference on Electro Information Technology; vol. 2005).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Intraperitoneal administration of 340 kDa human plasma butyrylcholinesterase increases the level of the enzyme in the cerebrospinal fluid of rats

Sáez-Valero, J., Pérez De Gracia, J. A. & Lockridge, O., Jul 22 2005, In : Neuroscience Letters. 383, 1-2, p. 93-98 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

Life without acetylcholinesterase: The implications of cholinesterase inhibitor toxicity in AChE-knockout mice

Lockridge, O., Duysen, E. G., Voelker, T., Thompson, C. M. & Schopfer, L. M., May 2005, In : Environmental Toxicology and Pharmacology. 19, 3, p. 463-469 7 p.

Research output: Contribution to journalArticle

20 Scopus citations

Molecular identification of Rhizomucor pusillus as a cause of sinus-orbital zygomycosis in a patient with acute myelogenous leukemia

Iwen, P. C., Freifeld, A. G., Sigler, L. & Tarantolo, S. R., Nov 2005, In : Journal of clinical microbiology. 43, 11, p. 5819-5821 3 p.

Research output: Contribution to journalArticle

23 Scopus citations

Reaction kinetics of biotinylated organophosphorus toxicant, FP-biotin, with human acetylcholinesterase and human butyrylcholinesterase

Schopfer, L. M., Voelker, T., Bartels, C. F., Thompson, C. M. & Lockridge, O., Apr 2005, In : Chemical Research in Toxicology. 18, 4, p. 747-754 8 p.

Research output: Contribution to journalArticle

25 Scopus citations

Role of water in aging of human butyrylcholinesterase inhibited by echothiophate: The crystal structure suggests two alternative mechanisms of aging

Nachon, F., Asojo, O. A., Borgstahl, G. E. O., Masson, P. & Lockridge, O., Feb 1 2005, In : Biochemistry. 44, 4, p. 1154-1162 9 p.

Research output: Contribution to journalArticle

88 Scopus citations

Subject protection and the risk-benefit relationship

Schonfeld, T. L., Brown, J. S. & Gordon, B. G., Sep 2005, In : American Journal of Bioethics. 5, 5, p. 22-23 2 p.

Research output: Contribution to journalComment/debate

3 Scopus citations
2004

Administration of oral probiotic bacteria to pregnant women causes temporary infantile colonization

Schultz, M., Göttl, C., Young, R. J., Iwen, P. & Vanderhoof, J. A., Mar 2004, In : Journal of pediatric gastroenterology and nutrition. 38, 3, p. 293-297 5 p.

Research output: Contribution to journalArticle

121 Scopus citations

Damped oscillatory hysteretic behaviour of butyrylcholinesterase with benzoylcholine as substrate

Masson, P., Goldstein, B. N., Debouzy, J. C., Froment, M. T., Lockridge, O. & Schopfer, L. M., Jan 2004, In : European Journal of Biochemistry. 271, 1, p. 220-234 15 p.

Research output: Contribution to journalArticle

30 Scopus citations

Genome diversity among regional populations of Francisella tularensis subspecies tularensis and Francisella tularensis subspecies holarctica isolated from the US

Samrakandi, M. M., Zhang, C., Zhang, M., Nietfeldt, J., Kim, J., Iwen, P. C., Olson, M. E., Fey, P. D., Duhamel, G. E., Hinrichs, S. H., Cirillo, J. D. & Benson, A. K., Aug 1 2004, In : FEMS Microbiology Letters. 237, 1, p. 9-17 9 p.

Research output: Contribution to journalArticle

24 Scopus citations