Research Output

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Article
1971

Transamidating enzymes. II. A continuous fluorescent method suited for automating measurements of factor XIII in plasma

Lorand, L., Lockridge, O. M., Campbell, L. K., Myhrman, R. & Bruner-Lorand, J., Nov 1971, In : Analytical Biochemistry. 44, 1, p. 221-231 11 p.

Research output: Contribution to journalArticle

85 Scopus citations
1972

Inactivation of a flavoprotein, lactate oxidase, by an acetylenic substrate.

Walsh, C. T., Schonbrunn, A., Lockridge, O., Massey, V. & Abeles, R. H., Sep 25 1972, In : Journal of Biological Chemistry. 247, 18, p. 6004-6006 3 p.

Research output: Contribution to journalArticle

65 Scopus citations

Mechanism of action of the flavoenzyme lactate oxidase.

Lockridge, O., Massey, V. & Sullivan, P. A., Dec 25 1972, In : Journal of Biological Chemistry. 247, 24, p. 8097-8106 10 p.

Research output: Contribution to journalArticle

112 Scopus citations
1973

Studies on the mechanism of action of the flavoenzyme lactate oxidase

Walsh, C., Lockridge, O., Massey, V. & Abeles, R., 1973, In : Journal of Biological Chemistry. 248, 20, p. 7049-7054 6 p.

Research output: Contribution to journalArticle

62 Scopus citations
1975

Citrulline metabolism in normal and citrullinemic human lymphocyte lines

Spector, E. B., Lockridge, O. & Bloom, A. D., Aug 1975, In : Biochemical Genetics. 13, 7-8, p. 471-485 15 p.

Research output: Contribution to journalArticle

12 Scopus citations
1976

Affinity electrophoresis, a new way of separating usual from atypical serum cholinesterases

Lockridge, O. & La Du, B. N., 1976, In : Unknown Journal. No. 397, p. No.87

Research output: Contribution to journalArticle

Comparative kinetics studies on human serum usual and atypical cholinesterases

Lockridge, O. & La Du, B. N., 1976, In : Federation Proceedings. 35, 3, p. No. 2240

Research output: Contribution to journalArticle

1977

Argininosuccinate synthetase activity in cultured human lymphocytes

Lockridge, O., Spector, E. B. & Bloom, A. D., Apr 1977, In : Biochemical Genetics. 15, 3-4, p. 395-407 13 p.

Research output: Contribution to journalArticle

12 Scopus citations
1978
108 Scopus citations
1979

Interchain disulfide bonds and subunit organization in human serum cholinesterase.

Lockridge, O., Eckerson, H. W. & La Du, B. N., Sep 10 1979, In : Journal of Biological Chemistry. 254, 17, p. 8324-8330 7 p.

Research output: Contribution to journalArticle

95 Scopus citations

Prolonged apnea following trimethaphan and succinylcholine

Poulton, T. J., James, F. M. & Lockridge, O., 1979, In : Anesthesiology. 50, 1, p. 54-56 3 p.

Research output: Contribution to journalArticle

16 Scopus citations
1980

Hydrolysis of diacetylmorphine (heroin) by human serum cholinesterase

Lockridge, O., Mottershaw-Jackson, N., Eckerson, H. W. & La Du, B. N., 1980, In : Journal of Pharmacology and Experimental Therapeutics. 215, 1, p. 1-8 8 p.

Research output: Contribution to journalArticle

123 Scopus citations
1981

Differential effect of limitation in oxygen supply on plaquing and multiplication of adenovirus and poliovirus

Dubes, G. R., Al-Moslih, M. I. & Sambol, A. R., Sep 1981, In : Archives of Virology. 70, 3, p. 247-254 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

Hydrolysis of methylprednisolone acetate by human serum cholinesterase

Myers, C. L., Lockridge, O. & LaDu, B. N., 1981, In : Pharmacologist. 23, 3, p. no. 510

Research output: Contribution to journalArticle

Prediction of drug sensitivity in individuals with atypical serum cholinesterase based on in vitro biochemical studies

Valentino, R. J., Lockridge, O., Eckerson, H. W. & La Du, B. N., Jun 15 1981, In : Biochemical Pharmacology. 30, 12, p. 1643-1649 7 p.

Research output: Contribution to journalArticle

29 Scopus citations
1982

Hydrolysis of methylprednisolone acetate by human serum cholinesterase

Myers, C., Lockridge, O. & La Du, B. N., 1982, In : Drug Metabolism and Disposition. 10, 3, p. 279-280 2 p.

Research output: Contribution to journalArticle

28 Scopus citations

Inactivation of transforming DNA by a transient product of the interaction of Cu2+ and hydroquinone

Dubes, G. R., Sambol, A. R., Al-Moslin, M. I. & Bradshaw, G. L., Dec 15 1982, In : Biochemical and Biophysical Research Communications. 109, 3, p. 888-894 7 p.

Research output: Contribution to journalArticle

2 Scopus citations
54 Scopus citations

Substance P Hydrolysis by Human Serum Cholinesterase

Lockridge, O., Jul 1982, In : Journal of Neurochemistry. 39, 1, p. 106-110 5 p.

Research output: Contribution to journalArticle

63 Scopus citations
1983

Immunological comparison of the usual and atypical human serum cholinesterase phenotypes

Eckerson, H. W., Oseroff, A., Lockridge, O. & La Du, B. N., Feb 1983, In : Biochemical Genetics. 21, 1-2, p. 93-108 16 p.

Research output: Contribution to journalArticle

10 Scopus citations
1984

Phenotypic suppression of opal mutants by L-tryptophan

Sambol, A. R. & Dubes, G. R., 1984, In : Microbios. 39, 155, p. 19-27 9 p.

Research output: Contribution to journalArticle

2 Scopus citations

Treatment of murine pulmonary cryptococcosis with ketoconazole and amphotericin B

Iwen, P. C., Miller, N. G. & McFadden, H. W., 1984, In : Journal of Infectious Diseases. 149, 4, p. 650 1 p.

Research output: Contribution to journalArticle

5 Scopus citations
1986

Amino acid sequence of the active site of human serum cholinesterase from usual, atypical, and atypical-silent genotypes

Lockridge, O. & La Du, B. N., Jun 1986, In : Biochemical Genetics. 24, 5-6, p. 485-498 14 p.

Research output: Contribution to journalArticle

16 Scopus citations

Enhancement of ketoconazole penetration across the blood-brain barrier of mice by dimethyl sulfoxide

Iwen, P. C. & Miller, N. G., 1986, In : Antimicrobial Agents and Chemotherapy. 30, 4, p. 617-618 2 p.

Research output: Contribution to journalArticle

Open Access
16 Scopus citations
1987

Brain cDNA clone for human cholinesterase.

McTiernan, C., Adkins, S., Chatonnet, A., Vaughan, T. A., Bartels, C. F., Kott, M., Rosenberry, T. L., La Du, B. N. & Lockridge, O., Oct 1987, In : Proceedings of the National Academy of Sciences of the United States of America. 84, 19, p. 6682-6686 5 p.

Research output: Contribution to journalArticle

Open Access
83 Scopus citations

Complete amino acid sequence of human serum cholinesterase

Lockridge, O., Bartels, C. F., Vaughan, T. A., Wong, C. K., Norton, S. E. & Johnson, L. L., 1987, In : Journal of Biological Chemistry. 262, 2, p. 549-557 9 p.

Research output: Contribution to journalArticle

296 Scopus citations

Location of disulfide bonds within the sequence of human serum cholinesterase

Lockridge, O., Adkins, S. & La Du, B. N., 1987, In : Journal of Biological Chemistry. 262, 27, p. 12945-12952 8 p.

Research output: Contribution to journalArticle

81 Scopus citations
1989

Acute lymphoblastic leukemia of NK-cell lineage: Responses to IL-2

Pirruccello, S. J., Bicak, M. S., Gordon, B. G., Gajl-Peczalska, K., Gnarra, D. J. & Coccia, P. F., 1989, In : Leukemia Research. 13, 9, p. 735-743 9 p.

Research output: Contribution to journalArticle

18 Scopus citations

Comparison of media for screening of diarrheic stools for the recovery of Clostridium difficile

Iwen, P. C., Booth, S. J. & Woods, G. L., 1989, In : Journal of clinical microbiology. 27, 9, p. 2105-2106 2 p.

Research output: Contribution to journalArticle

Open Access
11 Scopus citations

Experimental bacterial endophthalmitis following extracapsular lens extraction

Records, R. E. & Iwen, P. C., Nov 1989, In : Experimental Eye Research. 49, 5, p. 729-737 9 p.

Research output: Contribution to journalArticle

26 Scopus citations

Identification of the structural mutation responsible for the dibucaine-resistant (atypical) variant form of human serum cholinesterase

McGuire, M. C., Nogueira, C. P., Bartels, C. F., Lightstone, H., Hajra, A., Van der Spek, A. F. L., Lockridge, O. & La Du, B. N., 1989, In : Proceedings of the National Academy of Sciences of the United States of America. 86, 3, p. 953-957 5 p.

Research output: Contribution to journalArticle

Open Access
156 Scopus citations
1990
Open Access
12 Scopus citations

Evaluation of MicroScan for identification of Enterococcus species

Tritz, D. M., Iwen, P. C. & Woods, G. L., 1990, In : Journal of clinical microbiology. 28, 6, p. 1477-1478 2 p.

Research output: Contribution to journalArticle

Open Access
14 Scopus citations

Evidence for a single butyrylcholinesterase gene in individuals carrying the C5 plasma cholinesterase variant (CHE2)

Masson, P., Chatonnet, A. & Lockridge, O., Mar 12 1990, In : FEBS Letters. 262, 1, p. 115-118 4 p.

Research output: Contribution to journalArticle

24 Scopus citations

Identification of a frameshift mutation responsible for the silent phenotype of human serum cholinesterase, Gly 117 (GGT → GGAG)

Nogueira, C. P., McGuire, M. C., Graeser, C., Bartels, C. F., Arpagaus, M., Van Der Spek, A. F. L., Lightstone, H., Lockridge, O. & La Du, B. N., 1990, In : American Journal of Human Genetics. 46, 5, p. 934-942 9 p.

Research output: Contribution to journalArticle

55 Scopus citations

Phenotypic and molecular biological analysis of human butyrylcholinesterase variants

La Du, B. N., Bartels, C. F., Nogueira, C. P., Hajra, A., Lightstone, H., van der Spek, A. & Lockridge, O., Oct 1990, In : Clinical Biochemistry. 23, 5, p. 423-431 9 p.

Research output: Contribution to journalArticle

57 Scopus citations

Structure of the Gene for Human Butyrylcholinesterase. Evidence for a Single Copy

Arpagaus, M., Kott, M., Vatsis, K. P., Bartels, C. F., Du, B. N. L. & Lockridge, O., Jan 1 1990, In : Biochemistry. 29, 1, p. 124-131 8 p.

Research output: Contribution to journalArticle

135 Scopus citations
1991

Autoimmune neutropenia and Hodgkin’s disease: Successful treatment with intravenous gammaglobulin

Gordon, B. G., Kiwanuka, J. & Kadushin, J., 1991, In : Journal of Pediatric Hematology/Oncology. 13, 2, p. 164-167 4 p.

Research output: Contribution to journalArticle

8 Scopus citations

Cerebral infarction associated with protein C deficiency following allogeneic bone marrow transplantation

Gordon, B. G., Saving, K. L., McCallister, J. A., Warkentin, P. I., McConnell Roberts, J. R. W. M., Coccia, P. F. & Haire, W. D., 1991, In : Bone marrow transplantation. 8, 4, p. 323-325 3 p.

Research output: Contribution to journalArticle

20 Scopus citations
32 Scopus citations

Effect of 6-hydroxydopamine on murine hematopoietic stem cells: Enhanced cytotoxicity on megakaryocyte colony forming units

Gordon, B. G., DeBoer, J. M., Wooldridge, L. D. & Graham Sharp, J., 1991, In : Life Sciences. 49, 2, p. 121-127 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

Factors influencing determination of high-level aminoglycoside resistance in Enterococcus faecalis

Sahm, D. F., Boonlayangoor, S., Iwen, P. C., Baade, J. L. & Woods, G. L., 1991, In : Journal of clinical microbiology. 29, 9, p. 1934-1939 6 p.

Research output: Contribution to journalArticle

Open Access
12 Scopus citations

Factor V inhibitor developing after liver transplantation in a 3-year-old child

Gordon, B., Haire, W., Duggan, M., Langnas, A. & Shaw, B., 1991, In : Pediatrics. 88, 1, p. 156-158 3 p.

Research output: Contribution to journalArticle

13 Scopus citations

High frequency of antithrombin 3 and protein C deficiency following autologous bone marrow transplantation for lymphoma

Gordon, B., Haire, W., Kessinger, A., Duggan, M. & Armitage, J., 1991, In : Bone marrow transplantation. 8, 6, p. 497-502 6 p.

Research output: Contribution to journalArticle

70 Scopus citations
35 Scopus citations

Proposed nomenclature for human butyrylcholinesterase genetic variants identified by DNA sequencing

La Du, B. N., Bartels, C. F., Nogueira, C. P., Arpagaus, M. & Lockridge, O., Feb 1991, In : Cellular and molecular neurobiology. 11, 1, p. 79-89 11 p.

Research output: Contribution to journalArticle

50 Scopus citations
4 Scopus citations

The butyrylcholinesterase gene (BCHE) at 3q26.2 shows two RFLPs

Mcalpine, P. J., Dixon, M., Allderdice, P. W., Lockridge, O. & La Du, B. N., Sep 25 1991, In : Nucleic acids research. 19, 18, p. 5088 1 p.

Research output: Contribution to journalArticle

2 Scopus citations

The cloned butyrylcholinesterase (BCHE) gene maps to a single chromosome site, 3q26

Allderdice, P. W., Gardner, H. A. R., Galutira, D., Lockridge, O., Ladu, B. N. & McAlpine, P. J., Oct 1991, In : Genomics. 11, 2, p. 452-454 3 p.

Research output: Contribution to journalArticle

93 Scopus citations

The cloning and expression of a gene encoding old yellow enzyme from Saccharomyces carlsbergensis

Saito, K., Thiele, D. J., Davio, M., Lockridge, O. & Massey, V., 1991, In : Journal of Biological Chemistry. 266, 31, p. 20720-20724 5 p.

Research output: Contribution to journalArticle

83 Scopus citations