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Safety Considerations in the Laboratory Testing of Specimens Suspected or Known to Contain the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)

Iwen, P. C., Stiles, K. L. & Pentella, M. A., May 6 2020, In : Laboratory medicine. 51, 3, p. 239-242 4 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations
Open Access
10 Scopus citations

Screening assays for cholinesterases resistant to inhibition by organophosphorus toxicants

Wang, Y., Schopfer, L. M., Duysen, E. G., Nachon, F., Masson, P. & Lockridge, O., Jun 1 2004, In : Analytical Biochemistry. 329, 1, p. 131-138 8 p.

Research output: Contribution to journalArticle

9 Scopus citations

Selective review of external adverse events: one IRB's response to the avalanche of IND safety reports.

Gordon, B. & Prentice, E., 1999, In : IRB. 21, 3, p. 10-11 2 p.

Research output: Contribution to journalArticle

3 Scopus citations
68 Scopus citations

Sequence analysis of the RNA polymerase gene of foot-and-mouth disease virus serotype Asia 1

Manju, G., Ramamurthy, V., Bramhadev, P., Aniket, S., Gurumurthy, C. B., Divakar, H. & Chakradhar, T., 2001, In : Virus Genes. 22, 1, p. 21-26 6 p., 281660.

Research output: Contribution to journalArticle

10 Scopus citations
9 Scopus citations

Seroprevalence of West Nile virus infection in solid organ transplant recipients

Freifeld, A. G., Meza, J., Schweitzer, B., Shafer, L., Kalil, A. C. & Sambol, A. R., Apr 2010, In : Transplant Infectious Disease. 12, 2, p. 120-126 7 p.

Research output: Contribution to journalArticle

22 Scopus citations

Shared as well as distinct roles of EHD proteins revealed by biochemical and functional comparisons in mammalian cells and C. elegans

George, M., Ying, G. G., Rainey, M. A., Solomon, A., Parikh, P. T., Gao, Q., Band, V. & Band, H., 2007, In : BMC Cell Biology. 8, 3.

Research output: Contribution to journalArticle

80 Scopus citations

Signature Ions in MS/MS Spectra for Dansyl-Aminohexyl-QQIV Adducts on Lysine

Schopfer, L. M. & Lockridge, O., Jun 8 2020, In : Molecules. 25, 11

Research output: Contribution to journalArticle

Open Access

Smallpox vaccination of laboratory workers at US variola testing sites

Medcalf, S., Bilek, L., Hartman, T., Iwen, P. C., Leuschen, P., Miller, H., Anne, OK., Sayles, H. & Smith, P. W., Jul 23 2015, In : Emerging infectious diseases. 21, 8, p. 1437-1439 3 p.

Research output: Contribution to journalArticle

Specificity of ethephon as a butyrylcholinesterase inhibitor and phosphorylating agent

Haux, J. E., Lockridge, O. & Casida, J. E., Dec 1 2002, In : Chemical Research in Toxicology. 15, 12, p. 1527-1533 7 p.

Research output: Contribution to journalArticle

20 Scopus citations
1 Scopus citations

Structural and hydration changes in the active site gorge of phosporhylated butyrylcholinesterase accompanying the aging process

Masson, P., Fortier, P. L., Albaret, C., Cléry, C., Guerra, P. & Lockridge, O., May 14 1999, In : Chemico-Biological Interactions. 119-120, p. 17-27 11 p.

Research output: Contribution to journalArticle

3 Scopus citations

Structural approach to the aging of phosphylated cholinesterases

Masson, P., Nachon, F. & Lockridge, O., Sep 2010, In : Chemico-Biological Interactions. 187, 1-3, p. 157-162 6 p.

Research output: Contribution to journalArticle

45 Scopus citations

Structure of the Gene for Human Butyrylcholinesterase. Evidence for a Single Copy

Arpagaus, M., Kott, M., Vatsis, K. P., Bartels, C. F., Du, B. N. L. & Lockridge, O., Jan 1 1990, In : Biochemistry. 29, 1, p. 124-131 8 p.

Research output: Contribution to journalArticle

135 Scopus citations

Substrate activation in acetylcholinesterase induced by low pH or mutation in the π-cation subsite

Masson, P., Schopfer, L. M., Bartels, C. F., Froment, M. T., Ribes, F., Nachon, F. & Lockridge, O., Feb 11 2002, In : Biochimica et Biophysica Acta - Protein Structure and Molecular Enzymology. 1594, 2, p. 313-324 12 p.

Research output: Contribution to journalArticle

42 Scopus citations
4 Scopus citations
2 Scopus citations

Tetramerization domain of human butyrylcholinesterase is at the C-terminus

Blong, R. M., Bedows, E. & Lockridge, O., Nov 1 1997, In : Biochemical Journal. 327, 3, p. 747-757 11 p.

Research output: Contribution to journalArticle

72 Scopus citations
8 Scopus citations

The active site of human paraoxonase (PON1).

Josse, D., Lockridge, O., Xie, W., Bartels, C. F., Schopfer, L. M. & Masson, P., Dec 2001, In : Journal of applied toxicology : JAT. 21 Suppl 1, p. S7-S11

Research output: Contribution to journalArticle

69 Scopus citations

The butyrylcholinesterase knockout mouse as a model for human butyrylcholinesterase deficiency

Li, B., Duysen, E. G., Carlson, M. & Lockridge, O., Mar 2008, In : Journal of Pharmacology and Experimental Therapeutics. 324, 3, p. 1146-1154 9 p.

Research output: Contribution to journalArticle

64 Scopus citations

The butyrylcholinesterase knockout mouse is obese on a high-fat diet

Li, B., Duysen, E. G. & Lockridge, O., Sep 25 2008, In : Chemico-Biological Interactions. 175, 1-3, p. 88-91 4 p.

Research output: Contribution to journalArticle

53 Scopus citations

The butyrylcholinesterase K-variant shows similar cellular protein turnover and quaternary interaction to the wild-type enzyme

Altamirano, C. V., Bartels, C. F. & Lockridge, O., 2000, In : Journal of Neurochemistry. 74, 2, p. 869-877 9 p.

Research output: Contribution to journalArticle

40 Scopus citations

The C5 variant of the butyrylcholinesterase tetramer includes a noncovalently bound 60 kDa lamellipodin fragment

Schopfer, L. M., Delacour, H., Masson, P., Leroy, J., Krejci, E. & Lockridge, O., Jul 2017, In : Molecules. 22, 7, 1083.

Research output: Contribution to journalArticle

9 Scopus citations

The cloned butyrylcholinesterase (BCHE) gene maps to a single chromosome site, 3q26

Allderdice, P. W., Gardner, H. A. R., Galutira, D., Lockridge, O., Ladu, B. N. & McAlpine, P. J., Oct 1991, In : Genomics. 11, 2, p. 452-454 3 p.

Research output: Contribution to journalArticle

93 Scopus citations

The cloning and expression of a gene encoding old yellow enzyme from Saccharomyces carlsbergensis

Saito, K., Thiele, D. J., Davio, M., Lockridge, O. & Massey, V., 1991, In : Journal of Biological Chemistry. 266, 31, p. 20720-20724 5 p.

Research output: Contribution to journalArticle

83 Scopus citations

The endocytic recycling regulator EHD1 is essential for spermatogenesis and male fertility in mice

Rainey, M. A., George, M., Ying, G., Akakura, R., Burgess, D. J., Siefker, E., Bargar, T., Doglio, L., Crawford, S. E., Todd, G. L., Govindarajan, V., Hess, R. A., Band, V., Naramura, M. & Band, H., 2010, In : BMC Developmental Biology. 10, 37.

Research output: Contribution to journalArticle

38 Scopus citations

The endocytic recycling regulatory protein EHD1 Is required for ocular lens development

Arya, P., Rainey, M. A., Bhattacharyya, S., Mohapatra, B. C., George, M., Kuracha, M. R., Storck, M. D., Band, V., Govindarajan, V. & Band, H., Dec 1 2015, In : Developmental Biology. 408, 1, p. 41-55 15 p.

Research output: Contribution to journalArticle

4 Scopus citations

The kinetic study of the inhibition of human cholinesterases by demeton-S-methyl shows that cholinesterase-based titration methods are not suitable for this organophosphate

Bazire, A., Gillon, E., Lockridge, O., Vallet, V. & Nachon, F., Apr 2011, In : Toxicology in Vitro. 25, 3, p. 754-759 6 p.

Research output: Contribution to journalArticle

7 Scopus citations

The non-structural leader protein gene of foot-and-mouth disease virus is highly variable between serotypes

George, M., Venkataramanan, R., Gurumurthy, C. B. & Hemadri, D., 2001, In : Virus Genes. 22, 3, p. 271-278 8 p.

Research output: Contribution to journalArticle

20 Scopus citations

The pH dependence of dealkylation in soman-inhibited cholinesterases and their mutants: Further evidence for a push-pull mechanism

Saxena, A., Viragh, C., Frazier, D. S., Kovach, I. M., Maxwell, D. M., Lockridge, O. & Doctor, B. P., Oct 27 1998, In : Biochemistry. 37, 43, p. 15086-15096 11 p.

Research output: Contribution to journalArticle

36 Scopus citations

The proline-rich tetramerization peptides in equine serum butyrylcholinesterase

Biberoglu, K., Schopfer, L. M., Tacal, O. & Lockridge, O., Oct 2012, In : FEBS Journal. 279, 20, p. 3844-3858 15 p.

Research output: Contribution to journalArticle

22 Scopus citations

The role of cooperativity with Src in oncogenic transformation mediated by non-small cell lung cancer-associated EGF receptor mutants

Chung, B. M., Dimri, M., George, M., Reddi, A. L., Chen, G., Band, V. & Band, H., Apr 23 2009, In : Oncogene. 28, 16, p. 1821-1832 12 p.

Research output: Contribution to journalArticle

44 Scopus citations

The special pathogens research network: Enabling research readiness

Kraft, C. S., Kortepeter, M. G., Gordon, B., Sauer, L. M., Shenoy, E. S., Eiras, D. P., Larson, L. A., Garland, J. A., Mehta, A. K., Barrett, K., Price, C. S., Croyle, C., West, L. R., Noren, B., Kline, S., Arguinchona, C., Arguinchona, H., Grein, J. D., Connally, C., McLellan, S. & 8 others, Risi, G. F., Uyeki, T. M., Davey, R. T., Schweinle, J. E., Schwedhelm, M. M., Harvey, M., Hunt, R. C. & Kratochvil, C. J., Jan 1 2019, In : Health Security. 17, 1, p. 35-45 11 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

The use of normal children as participants in research on therapy

Gordon, B., Prentice, E. & Reitemeier, P., 1996, In : IRB Ethics and Human Research. 18, 3, p. 5-8 4 p.

Research output: Contribution to journalArticle

6 Scopus citations

The Use of TKM-100802 and Convalescent Plasma in 2 Patients with Ebola Virus Disease in the United States

Kraft, C. S., Hewlett, A. L., Koepsell, S. A., Winkler, A. M., Kratochvil, C. J., Larson, L., Varkey, J. B., Mehta, A. K., Lyon, G. M., Friedman-Moraco, R. J., Marconi, V. C., Hill, C. E., Sullivan, J. N., Johnson, D. W., Lisco, S. J., Mulligan, M. J., Uyeki, T. M., McElroy, A. K., Sealy, T., Campbell, S. & 236 others, Spiropoulou, C., Ströher, U., Crozier, I., Sacra, R., Connor, M. J., Sueblinvong, V., Franch, H. A., Smith, P. W., Ribner, B. S., Schwedhelm, S., Boulter, K., Beam, E. L., Gibbs, S., Lowe, J-M. J., Piquette, C. A., Bailey, K. L., Auxier, J., Boer, B., Hanson, T., Kaseman, J., Khan, M. S., Rhee, J. H., Wells, A., Florescu, D. F., Kalil, A. C., Rupp, M. E., Becker, V., Boeckman, B., Elder, E., Fitch, A., Flood, E., Freml, M., Frigge, R., Hanzlik, K. A., Jensen, L., Kraus, N., Molacek, D., Nevins, J., Parker, A., Peters, J., Rand, C., Roesler, K., Ryalls, K., Shradar, M., Strain, A., Sunderman, T., Sundermeier, J., Swanhorst, J., Vasa, A., Bellinghausen, J., Freihaut, F., Denny, S., Mainelli, L., Pinkney, D., Ray, D., Jevne, J., Knight, K., McCroy, D., Nadeau, R., Nightser, A., Iwen, P. C., Sambol, T., Herrera, V., Morgan, D., Trotter, S., Kerby, A., Peters, S., Southern, T., Murphy, C., Morris, R., Nuss, S., Franco, T., Ogden, C., Lazure, J., Straub, D., Hinrichs, S. H., Plumb, T. J., Florescu, M. C., Becker, J., Souchek, J., Beck, J., Heires, P., Gordon, B., Paulsen, G., Wolford, B., Petersen, J., Marion, N., Hayes, K., Tyner, K., Wilson, T., Baltes, P., Nowatzke, J., Nguyen, J., Turner, P., Boonstra, B., Jelden, K., Portrey, R., Stringfield, D., Scofield, B., Svanda, G., Horihan, J., Dahl, C., Bruno, M., Malm, K., Litz, R., Fehringer, J., Paladino, K., Opp, T., Bell, S., Adams, A., Allen, M. B., Bachman, R., Bornstein, W., Cantrell, D., Cosper, P., Feistritzer, N., Fox, J., Gartland, B., Goodman, J., Grant, S., Howard-Crow, D., Horowitz, I., Pugh, D., Ritenour, C., Ash, T., Barnes, C., Calhoun, J., Chapman, L., Daye, T., Durr, H., Evans, S., Gentry, J., Ginnane, J., Haynes, C., Hill, C., Hillis, D., Johnson, C., Loomis, J., Mamora, J., Mitchell, L., Morgan, J., Osakwe, N., Owen, J., Piazza, S., Shirley, K., Siddens, J., Silas, C., Slabach, J., Tirador, E., Todd, D., Vanairsdale, S., Brammer, N., Buchanan, J., Burd, E., Cardella, J., Eaves, B., Evans, C., Hostetler, K., Jenkins, K., Lindsey, M., Magee, J., Powers, R., Ritchie, J., Ryan, E., Bonds, S., Emamifar, A., Kuban, T., Pack, J., Rogers, S., Golston, G., Kaufman, S., Olinger, P., Olinger, S., Rengarajan, K., Thomaston, S., Beck, E., Desroches, P., Hall, C., Walker, C., Bryant, C., Hackman, B., Howard, R., Jones, M., Broughton, J., Frisle, B., Jackson, R., Lewis, J., Brown-Haithco, R., Gartin, M. L., Geralds-Washington, E., James-Jones, R., Miller, D., Stark, D., McGee, G., Jones, P., Scott-Harris, L., Cain, J., Davis, R., Johnson, T., Pickett, T., Shaw, A., Truesdale, T., Blum, J., Hill, L., Sevransky, J., Zivot, J., Walker, S., Klopman, M., Matkins, R., Meechan, C., Meechan, P., Schwock, K., Schuck, J., Stack, K., Wolf, F., Bray, B., Isakov, A., Shartar, S., Miles, W., Jamison, A., Arevalo, J., Stallings, G., Christenbury, J., Dollard, V., De Gennaro, M., Korschun, H., Seideman, N., Ziegler, T., Griffith, D. P., Dave, N., Wall, S., Hall, M., McGhee, D., Clarke, T., Vaught, R. & Peterson-Pileri, K., Aug 15 2015, In : Clinical Infectious Diseases. 61, 4, p. 496-502 7 p.

Research output: Contribution to journalArticle

101 Scopus citations

Thrombotic complications of BMT: Association with protein C deficiency

Gordon, B. G., Haire, W. D., Patton, D. F., Manno, P. J. & Reed, E. C., 1993, In : Bone marrow transplantation. 11, 1, p. 61-65 5 p.

Research output: Contribution to journalArticle

26 Scopus citations

Tissue distribution of human acetylcholinesterase and butyrylcholinesterase messenger RNA

Jbilo, O., Bartels, C. F., Chatonnet, A., Toutant, J. P. & Lockridge, O., Nov 1994, In : Toxicon. 32, 11, p. 1445-1457 13 p.

Research output: Contribution to journalArticle

66 Scopus citations

Transglutaminase-mediated remodeling of the human erythrocyte membrane skeleton: Relevance for erythrocyte diseases with shortened cell lifespan

Lor, L., Murthy, S. N. P., Khan, A. A., Xue, W., Lockridge, O. & Chishti, A. H., 2011, In : Advances in Enzymology and Related Areas of Molecular Biology. 78 1, p. 385-414 30 p.

Research output: Contribution to journalArticle

3 Scopus citations

Treatment of murine pulmonary cryptococcosis with ketoconazole and amphotericin B

Iwen, P. C., Miller, N. G. & McFadden, H. W., 1984, In : Journal of Infectious Diseases. 149, 4, p. 650 1 p.

Research output: Contribution to journalArticle

5 Scopus citations

Treatment of veno-occlusive disease of the liver with bolus tissue plasminogen activator and continuous infusion antithrombin III concentrate

Patton, D. F., Harper, J. L., Wooldridge, T. N., Gordon, B. G., Coccia, P. & Haire, W. D., Mar 1996, In : Bone marrow transplantation. 17, 3, p. 443-447 5 p.

Research output: Contribution to journalArticle

21 Scopus citations

Tryptophan residue(s) as major components of the human serum paraoxonase active site

Josse, D., Xie, W., Masson, P., Schopfer, L. M. & Lockridge, O., May 14 1999, In : Chemico-Biological Interactions. 119-120, p. 79-84 6 p.

Research output: Contribution to journalArticle

13 Scopus citations
26 Scopus citations

U.S. ebola treatment center clinical laboratory support

Jelden, K. C., Iwen, P. C., Herstein, J. J., Biddinger, P. D., Kraft, C. S., Saiman, L., Smith, P. W., Hewlett, A. L., Gibbs, S. G. & Lowe, J. J., Apr 2016, In : Journal of clinical microbiology. 54, 4, p. 1031-1035 5 p.

Research output: Contribution to journalArticle

16 Scopus citations

U.S. High-Level Isolation Unit Clinical Laboratory Capabilities Update

Herstein, J. J., Iwen, P. C., Jelden, K. C., Biddinger, P. D., Gibbs, S. G., Le, A. B., Hewlett, A. L. & Lowe, J. J., Feb 1 2018, In : Journal of clinical microbiology. 56, 2

Research output: Contribution to journalArticle

4 Scopus citations

Ultrastructural characterization of the neuromuscular junction in diaphragm of the acetylcholinesterase knockout mouse

Hamilton, T. A., Sheridan, R. E., Deshpande, S. S., Lockridge, O. & Adler, M., 2002, In : Microscopy and Microanalysis. 8, SUPPL. 2, p. 940-941 2 p.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations