Research Output

Filter
Article
2016
9 Scopus citations
2 Scopus citations

Molecular polymorphism of human enzymes as the basis of individual sensitivity to drugs. Supercomputer-assisted modeling as a tool for analysis of structural changes and enzymatic activity of proteins

Varfolomeev, S. D., Lushchekina, S. V., Nemukhin, A. V., Kulakova, A. M., Kots, E. D., Makhaeva, G. F., Delacour, H., Lockridge, O. & Masson, P., Jun 1 2016, In : Russian Chemical Bulletin. 65, 6, p. 1592-1607 16 p.

Research output: Contribution to journalArticle

4 Scopus citations

Monoclonal antibodies to human butyrylcholinesterase reactive with butyrylcholinesterase in animal plasma

Peng, H., Brimijoin, S., Hrabovska, A., Krejci, E., Blake, T. A., Johnson, R. C., Masson, P. & Lockridge, O., Jan 5 2016, In : Chemico-Biological Interactions. 243, p. 82-90 9 p.

Research output: Contribution to journalArticle

8 Scopus citations

Nocardia arthritidis as a cause of disseminated nocardiosis in a patient with chronic lymphocytic leukemia

Roberts, A. L., Davidson, R. M., Freifeld, A. G. & Iwen, P. C., 2016, In : IDCases. 6, p. 68-71 4 p.

Research output: Contribution to journalArticle

1 Scopus citations

Origin of polyproline-rich peptides in human butyrylcholinesterase tetramers

Peng, H., Schopfer, L. M. & Lockridge, O., Nov 25 2016, In : Chemico-Biological Interactions. 259, p. 63-69 7 p.

Research output: Contribution to journalArticle

13 Scopus citations

Possible airborne person-to-person transmission of mycobacterium bovis — Nebraska 2014–2015

Buss, B. F., Keyser-Metobo, A., Rother, J., Holtz, L., Gall, K., Jereb, J., Murphy, C. N., Iwen, P. C., Robbe-Austerman, S., Holcomb, M. A. & Infield, P., Mar 4 2016, In : Morbidity and Mortality Weekly Report. 65, 8, p. 197-201 5 p.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations

Reclassification of Wolbachia persica as Francisella persica comb. nov. and emended description of the family Francisellaceae

Larson, M. A., Nalbantoglu, U., Sayood, K., Zentz, E. B., Cer, R. Z., Iwen, P. C., Francesconi, S. C., Bishop-Lilly, K. A., Mokashi, V. P., Sjöstedt, A. & Hinrichs, S. H., Mar 2016, In : International Journal of Systematic and Evolutionary Microbiology. 66, 3, p. 1200-1205 6 p.

Research output: Contribution to journalArticle

17 Scopus citations
8 Scopus citations

U.S. ebola treatment center clinical laboratory support

Jelden, K. C., Iwen, P. C., Herstein, J. J., Biddinger, P. D., Kraft, C. S., Saiman, L., Smith, P. W., Hewlett, A. L., Gibbs, S. G. & Lowe, J. J., Apr 2016, In : Journal of clinical microbiology. 54, 4, p. 1031-1035 5 p.

Research output: Contribution to journalArticle

16 Scopus citations
2015
26 Scopus citations

Comparison of 5 monoclonal antibodies for immunopurification of human butyrylcholinesterase on Dynabeads: KD values, binding pairs, and amino acid sequences

Peng, H., Brimijoin, S., Hrabovska, A., Targosova, K., Krejci, E., Blake, T. A., Johnson, R. C., Masson, P. & Lockridge, O., Oct 5 2015, In : Chemico-Biological Interactions. 240, p. 336-345 10 p.

Research output: Contribution to journalArticle

14 Scopus citations

Comparison of FilmArray and quantitative real-time reverse transcriptase PCR for detection of zaire ebolavirus from contrived and clinical specimens

Southern, T. R., Racsa, L. D., Albariño, C. G., Fey, P. D., Hinrichs, S. H., Murphy, C. N., Herrera, V. L., Sambol, A. R., Hill, C. E., Ryan, E. L., Kraft, C. S., Campbell, S., Sealy, T. K., Schuh, A., Ritchie, J. C., Lyon, G. M., Mehta, A. K., Varkey, J. B., Ribner, B. S., Brantly, K. P. & 3 others, Ströher, U., Iwen, P. C. & Burd, E. M., Sep 1 2015, In : Journal of clinical microbiology. 53, 9, p. 2956-2960 5 p.

Research output: Contribution to journalArticle

27 Scopus citations

Hemagglutinin-based polyanhydride nanovaccines against H5N1 infuenza elicit protective virus neutralizing titers and cell-mediated immunity

Ross, K. A., Lyod, H., Wu, W., Huntimer, L., Ahmed, S., Sambol, A., Broderick, S., Flickinger, Z., Rajan, K., Bronich, T., Mallapragada, S., Wannemuehler, M. J., Carpenter, S. & Narasimhan, B., 2015, In : International journal of nanomedicine. 10, p. 229-243 15 p.

Research output: Contribution to journalArticle

27 Scopus citations
46 Scopus citations

Pure human butyrylcholinesterase hydrolyzes octanoyl ghrelin to desacyl ghrelin

Schopfer, L. M., Lockridge, O. & Brimijoin, S., Dec 1 2015, In : General and Comparative Endocrinology. 224, p. 61-68 8 p.

Research output: Contribution to journalArticle

30 Scopus citations

Smallpox vaccination of laboratory workers at US variola testing sites

Medcalf, S., Bilek, L., Hartman, T., Iwen, P. C., Leuschen, P., Miller, H., Anne, OK., Sayles, H. & Smith, P. W., Jul 23 2015, In : Emerging infectious diseases. 21, 8, p. 1437-1439 3 p.

Research output: Contribution to journalArticle

2 Scopus citations

The endocytic recycling regulatory protein EHD1 Is required for ocular lens development

Arya, P., Rainey, M. A., Bhattacharyya, S., Mohapatra, B. C., George, M., Kuracha, M. R., Storck, M. D., Band, V., Govindarajan, V. & Band, H., Dec 1 2015, In : Developmental Biology. 408, 1, p. 41-55 15 p.

Research output: Contribution to journalArticle

4 Scopus citations

The Use of TKM-100802 and Convalescent Plasma in 2 Patients with Ebola Virus Disease in the United States

Kraft, C. S., Hewlett, A. L., Koepsell, S. A., Winkler, A. M., Kratochvil, C. J., Larson, L., Varkey, J. B., Mehta, A. K., Lyon, G. M., Friedman-Moraco, R. J., Marconi, V. C., Hill, C. E., Sullivan, J. N., Johnson, D. W., Lisco, S. J., Mulligan, M. J., Uyeki, T. M., McElroy, A. K., Sealy, T., Campbell, S. & 236 others, Spiropoulou, C., Ströher, U., Crozier, I., Sacra, R., Connor, M. J., Sueblinvong, V., Franch, H. A., Smith, P. W., Ribner, B. S., Schwedhelm, S., Boulter, K., Beam, E. L., Gibbs, S., Lowe, J-M. J., Piquette, C. A., Bailey, K. L., Auxier, J., Boer, B., Hanson, T., Kaseman, J., Khan, M. S., Rhee, J. H., Wells, A., Florescu, D. F., Kalil, A. C., Rupp, M. E., Becker, V., Boeckman, B., Elder, E., Fitch, A., Flood, E., Freml, M., Frigge, R., Hanzlik, K. A., Jensen, L., Kraus, N., Molacek, D., Nevins, J., Parker, A., Peters, J., Rand, C., Roesler, K., Ryalls, K., Shradar, M., Strain, A., Sunderman, T., Sundermeier, J., Swanhorst, J., Vasa, A., Bellinghausen, J., Freihaut, F., Denny, S., Mainelli, L., Pinkney, D., Ray, D., Jevne, J., Knight, K., McCroy, D., Nadeau, R., Nightser, A., Iwen, P. C., Sambol, T., Herrera, V., Morgan, D., Trotter, S., Kerby, A., Peters, S., Southern, T., Murphy, C., Morris, R., Nuss, S., Franco, T., Ogden, C., Lazure, J., Straub, D., Hinrichs, S. H., Plumb, T. J., Florescu, M. C., Becker, J., Souchek, J., Beck, J., Heires, P., Gordon, B., Paulsen, G., Wolford, B., Petersen, J., Marion, N., Hayes, K., Tyner, K., Wilson, T., Baltes, P., Nowatzke, J., Nguyen, J., Turner, P., Boonstra, B., Jelden, K., Portrey, R., Stringfield, D., Scofield, B., Svanda, G., Horihan, J., Dahl, C., Bruno, M., Malm, K., Litz, R., Fehringer, J., Paladino, K., Opp, T., Bell, S., Adams, A., Allen, M. B., Bachman, R., Bornstein, W., Cantrell, D., Cosper, P., Feistritzer, N., Fox, J., Gartland, B., Goodman, J., Grant, S., Howard-Crow, D., Horowitz, I., Pugh, D., Ritenour, C., Ash, T., Barnes, C., Calhoun, J., Chapman, L., Daye, T., Durr, H., Evans, S., Gentry, J., Ginnane, J., Haynes, C., Hill, C., Hillis, D., Johnson, C., Loomis, J., Mamora, J., Mitchell, L., Morgan, J., Osakwe, N., Owen, J., Piazza, S., Shirley, K., Siddens, J., Silas, C., Slabach, J., Tirador, E., Todd, D., Vanairsdale, S., Brammer, N., Buchanan, J., Burd, E., Cardella, J., Eaves, B., Evans, C., Hostetler, K., Jenkins, K., Lindsey, M., Magee, J., Powers, R., Ritchie, J., Ryan, E., Bonds, S., Emamifar, A., Kuban, T., Pack, J., Rogers, S., Golston, G., Kaufman, S., Olinger, P., Olinger, S., Rengarajan, K., Thomaston, S., Beck, E., Desroches, P., Hall, C., Walker, C., Bryant, C., Hackman, B., Howard, R., Jones, M., Broughton, J., Frisle, B., Jackson, R., Lewis, J., Brown-Haithco, R., Gartin, M. L., Geralds-Washington, E., James-Jones, R., Miller, D., Stark, D., McGee, G., Jones, P., Scott-Harris, L., Cain, J., Davis, R., Johnson, T., Pickett, T., Shaw, A., Truesdale, T., Blum, J., Hill, L., Sevransky, J., Zivot, J., Walker, S., Klopman, M., Matkins, R., Meechan, C., Meechan, P., Schwock, K., Schuck, J., Stack, K., Wolf, F., Bray, B., Isakov, A., Shartar, S., Miles, W., Jamison, A., Arevalo, J., Stallings, G., Christenbury, J., Dollard, V., De Gennaro, M., Korschun, H., Seideman, N., Ziegler, T., Griffith, D. P., Dave, N., Wall, S., Hall, M., McGhee, D., Clarke, T., Vaught, R. & Peterson-Pileri, K., Aug 15 2015, In : Clinical Infectious Diseases. 61, 4, p. 496-502 7 p.

Research output: Contribution to journalArticle

101 Scopus citations
2014

A kinase inhibitor screen reveals protein kinase C-dependent endocytic recycling of ErbB2 in breast cancer cells

Bailey, T. A., Luan, H., Tom, E., Bielecki, T. A., Mohapatra, B., Ahmad, G., George, M., Kelly, D. L., Natarajan, A., Raja, S. M., Band, V. & Band, H., Oct 31 2014, In : Journal of Biological Chemistry. 289, 44, p. 30443-30458 16 p.

Research output: Contribution to journalArticle

20 Scopus citations

An integrated approach to laboratory testing for patients with Ebola virus disease

Iwen, P. C., Garrett, J. L., Gibbs, S. G., Lowe, J. J., Herrera, V. L., Sambol, A. R., Stiles, K., Wisecarver, J. L., Salerno, K. J., Pirruccello, S. J. & Hinrichs, S. H., Nov 1 2014, In : Laboratory medicine. 45, 4, p. e146-e151

Research output: Contribution to journalArticle

27 Scopus citations

Antiproliferative activity of novel imidazopyridine derivatives on castration-resistant human prostate cancer cells

Muniyan, S., Chou, Y. W., Ingersoll, M. A., Devine, A., Morris, M., Odero-Marah, V. A., Khan, S. A., Chaney, W. G., Bu, X. R. & Lin, M. F., 2014, In : Cancer Letters. 353, 1, p. 59-67 9 p.

Research output: Contribution to journalArticle

20 Scopus citations

Bacteremia caused by microbacterium binotii in a patient with sickle cell anemia

Buss, S. N., Starlin, R. & Iwen, P. C., Jan 2014, In : Journal of clinical microbiology. 52, 1, p. 379-381 3 p.

Research output: Contribution to journalArticle

6 Scopus citations

Characterization of a novel BCHE "silent" allele: Point mutation (p.Val204Asp) causes loss of activity and prolonged apnea with suxamethonium

Delacour, H., Lushchekina, S., Mabboux, I., Bousquet, A., Ceppa, F., Schopfer, L. M., Lockridge, O. & Masson, P., Jul 23 2014, In : PloS one. 9, 7, e101552.

Research output: Contribution to journalArticle

22 Scopus citations

Characterization of a novel butyrylcholinesterase point mutation (p.Ala34Val), "silent" with mivacurium

Delacour, H., Lushchekina, S., Mabboux, I., Ceppa, F., Masson, P., Schopfer, L. M. & Lockridge, O., Dec 1 2014, In : Biochemical Pharmacology. 92, 3, p. 476-483 8 p.

Research output: Contribution to journalArticle

15 Scopus citations
3 Scopus citations

Detection of cresyl phosphate-modified butyrylcholinesterase in human plasma for chemical exposure associated with aerotoxic syndrome

Schopfer, L. M., Masson, P., Lamourette, P., Simon, S. & Lockridge, O., Sep 15 2014, In : Analytical Biochemistry. 461, p. 17-26 10 p.

Research output: Contribution to journalArticle

15 Scopus citations
13 Scopus citations

Method for investigating nursing behaviors related to isolation care

Beam, E. L., Gibbs, S. G., Hewlett, A. L., Iwen, P. C., Nuss, S. L. & Smith, P. W., 2014, In : American Journal of Infection Control. 42, 11, p. 1152-1156 5 p.

Research output: Contribution to journalArticle

15 Scopus citations

No girls allowed: A sponsor's rejection of one IRB's contraception policy

Brown, J. S., Schonfeld, T. L., Amoura, N. J. & Gordon, B., Nov 1 2014, In : IRB Ethics and Human Research. 36, 6, p. 13-15 3 p.

Research output: Contribution to journalArticle

1 Scopus citations

Polyproline promotes tetramerization of recombinant human butyrylcholinesterase

Larson, M. A., Lockridge, O. & Hinrichs, S. H., Sep 1 2014, In : Biochemical Journal. 462, 2, p. 329-335 7 p.

Research output: Contribution to journalArticle

19 Scopus citations
2013

A function for EHD family proteins in unidirectional retrograde dendritic transport of BACE1 and alzheimer's disease Aβ production

Buggia-Prévot, V., Fernandez, C. G., Udayar, V., Vetrivel, K. S., Elie, A., Roseman, J., Sasse, V. A., Lefkow, M., Meckler, X., Bhattacharyya, S., George, M., Kar, S., Bindokas, V. P., Parent, A. T., Rajendran, L., Band, H., Vassar, R. & Thinakaran, G., Dec 26 2013, In : Cell Reports. 5, 6, p. 1552-1563 12 p.

Research output: Contribution to journalArticle

44 Scopus citations

Application of chromosomal DNA and protein targeting for the identification of Yersinia pestis

Larson, M. A., Ding, S. J., Slater, S. R., Hanway, A., Bartling, A. M., Fey, P. D., Lockridge, O., Francesconi, S. C. & Hinrichs, S. H., Jun 2013, In : Proteomics - Clinical Applications. 7, 5-6, p. 416-423 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

A pregnancy testing policy for women enrolled in clinical trials

Schonfeld, T., Schmid, K. K., Brown, J. S., Jean Amoura, N. & Gordon, B., 2013, In : IRB Ethics and Human Research. 35, 6, p. 9-15 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

Clinical pharmacology of etoposide in children undergoing autologous stem cell transplantation for various solid tumours

Baheti, G., McGuire, T. R., Davda, J. P., Manouilov, K. K., Wall, D., Gwilt, P. R. & Gordon, B. B., Mar 2013, In : Xenobiotica. 43, 3, p. 276-282 7 p.

Research output: Contribution to journalArticle

2 Scopus citations
1 Scopus citations
20 Scopus citations
7 Scopus citations
32 Scopus citations

Evaluation of ambulance decontamination using gaseous chlorine dioxide

Lowe, J. J., Hewlett, A. L., Iwen, P. C., Smith, P. W. & Gibbs, S. G., Jul 2013, In : Prehospital Emergency Care. 17, 3, p. 401-408 8 p.

Research output: Contribution to journalArticle

12 Scopus citations

Human serum albumin-based design of a diflunisal prodrug

Yang, F., Ma, Z. Y., Zhang, Y., Li, G. Q., Li, M., Qin, J. K., Lockridge, O. & Liang, H., Aug 2013, In : European Journal of Pharmaceutics and Biopharmaceutics. 84, 3, p. 549-554 6 p.

Research output: Contribution to journalArticle

20 Scopus citations
11 Scopus citations

Inhibition pathways of the potent organophosphate CBDP with cholinesterases revealed by X-ray crystallographic snapshots and mass spectrometry

Carletti, E., Colletier, J. P., Schopfer, L. M., Santoni, G., Masson, P., Lockridge, O., Nachon, F. & Weik, M., Feb 18 2013, In : Chemical Research in Toxicology. 26, 2, p. 280-289 10 p.

Research output: Contribution to journalArticle

24 Scopus citations

Mass Spectrometry Method to Identify Aging Pathways of Sp- and Rp-Tabun Adducts on Human Butyrylcholinesterase Based on the Acid Labile P-N Bond

Jiang, W., Cashman, J. R., Nachon, F., Masson, P., Schopfer, L. M. & Lockridge, O., Apr 2013, In : Toxicological Sciences. 132, 2, p. 390-398 9 p.

Research output: Contribution to journalArticle

12 Scopus citations

Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry of titanium oxide-enriched peptides for detection of aged organophosphorus adducts on human butyrylcholinesterase

Jiang, W., Murashko, E. A., Dubrovskii, Y. A., Podolskaya, E. P., Babakov, V. N., Mikler, J., Nachon, F., Masson, P., Schopfer, L. M. & Lockridge, O., 2013, In : Analytical Biochemistry. 439, 2, p. 132-141 10 p.

Research output: Contribution to journalArticle

17 Scopus citations

Newly observed spontaneous activation of ethephon as a butyrylcholinesterase inhibitor

Liyasova, M. S., Schopfer, L. M., Kodani, S., Lantz, S. R., Casida, J. E. & Lockridge, O., Mar 18 2013, In : Chemical Research in Toxicology. 26, 3, p. 422-431 10 p.

Research output: Contribution to journalArticle

5 Scopus citations

Noncholinesterase Protein Targets of Organophosphorus Pesticides

Lockridge, O., 2013, In : Advances in Molecular Toxicology. 7, p. 179-205 27 p.

Research output: Contribution to journalArticle

1 Scopus citations

Observations on hospital room contamination testing

Smith, P. W., Gibbs, S., Sayles, H., Hewlett, A., Rupp, M. E. & Iwen, P. C., 2013, In : Healthcare Infection. 18, 1, p. 10-13 4 p.

Research output: Contribution to journalArticle

11 Scopus citations

PHOS-select iron affinity beads enrich peptides for the detection of organophosphorus adducts on albumin

Jiang, W., Dubrovskii, Y. A., Podolskaya, E. P., Murashko, E. A., Babakov, V., Nachon, F., Masson, P., Schopfer, L. M. & Lockridge, O., Dec 16 2013, In : Chemical Research in Toxicology. 26, 12, p. 1917-1925 9 p.

Research output: Contribution to journalArticle

10 Scopus citations