University of Nebraska Medical Center

Projects

Projects per year 1974 1985 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2021

• 15 Active
• 689 Finished
• 1583 Not started

Projects per year

Search results

• CNS Delivery of Activated Antiviral Drugs with Reduced Neurotoxicity (Nano-NRTIs)

  Vinogradov, S. V. & Gorantla, S.

  National Institutes of Health

  7/1/11 → 6/30/16

  Project: Research project

  • Reverse Transcriptase Inhibitors 100%
  • Nucleosides 87%
  • Antiviral Agents 61%
  • Highly Active Antiretroviral Therapy 48%
  • Blood-Brain Barrier 35%

• Upgrade of 7T MRI Research System

  Boska, M. D.

  National Institutes of Health

  7/1/11 → 6/30/12

  Project: Research project

  • magnetic resonance imaging 100%
  • image analysis 85%
  • nanoparticles 36%
  • animal disease models 30%
  • iron oxides 24%

• Methamphetamine and HIV: Defective immunity with CD8 T cell dysfunction

  Fox, H. S. & Sarvetnick, N. E.

  National Institutes of Health

  7/15/11 → 5/31/16

  Project: Research project

  • Methamphetamine 100%
  • Immunity 60%
  • HIV 54%
  • T-Lymphocytes 47%
  • Immune System 22%

• Protein Self-Assembly into Nanoaggregates

  Lyubchenko, Y. L.

  National Institutes of Health

  8/1/11 → 8/31/19

  Project: Research project

  • Self assembly 100%
  • Proteins 79%
  • Agglomeration 73%
  • Oligomers 69%
  • Dimers 24%

• Role of Claudin-2 in Inflammatory Diseases and Colon Cancer

  Singh, A. B.

  National Institutes of Health

  8/3/11 → 5/31/16

  Project: Research project

  • Claudin-2 100%
  • Colonic Neoplasms 48%
  • Inflammatory Bowel Diseases 31%
  • Claudins 18%
  • Permeability 17%

• Altered Lipid Droplet Trafficking: Role in Alcoholic Fatty Liver Disease

  Casey, C. A. & Mc Niven, M. A.

  National Institutes of Health

  8/10/11 → 4/30/21

  Project: Research project

  • liver diseases 100%
  • fatty liver 96%
  • droplets 77%
  • lipids 45%
  • hepatocytes 43%

• Are IL-18 receptor-bearing CD8 T cells pathogenic in human Type 1 diabetes?

  Sarvetnick, N. E.

  National Institutes of Health

  8/15/11 → 7/31/13

  Project: Research project

  • Interleukin-18 Receptors 100%
  • Type 1 Diabetes Mellitus 42%
  • T-Lymphocytes 36%
  • Population 27%
  • Clinical Trials 23%

• Non-Invasive Treatment of Abdominal Aortic Aneurysm Clinical Trial (N-TA^3CT )

  Matsumura, J. S., Terrin, M. L., Curci, J. & Baxter, T.

  National Institutes of Health

  8/15/11 → 2/28/18

  Project: Research project

  • Abdominal Aortic Aneurysm 100%
  • Clinical Trials 51%
  • Doxycycline 48%
  • Aneurysm 26%
  • Placebos 16%

• Central States Center for Agricultural Safety and Health (CS-CASH)

  Rautiainen, R.

  National Institutes of Health

  9/1/11 → 8/31/21

  Project: Research project

  • health 100%
  • farm 55%
  • hearing protection 49%
  • public health 43%
  • sleep 32%

• Regulatory Functions of APE1 acetylation

  Bhakat, K. K.

  National Institutes of Health

  9/1/11 → 7/31/16

  Project: Research project

  • Acetylation 100%
  • DNA Repair 74%
  • Apoptosis 19%
  • DNA 16%
  • Cell Survival 14%

• Novel neutrophil autoantigens in systemic lupus erythematosus

  Su, K.

  National Institutes of Health

  9/12/11 → 8/31/16

  Project: Research project

  • Systemic Lupus Erythematosus 100%
  • Autoantigens 99%
  • Neutrophils 83%
  • Autoantibodies 53%
  • Antibodies 34%

• A novel combination therapy for the treatment of Pancreatic adenocarcinoma

  Hollingsworth, T.

  National Institutes of Health

  9/15/11 → 8/31/14

  Project: Research project

  • gemcitabine 100%
  • Rosiglitazone 69%
  • Adenocarcinoma 55%
  • Pancreatic Neoplasms 32%
  • Peroxisome Proliferator-Activated Receptors 31%

• Role of BK-alpha/beta 4 in renal secretion

  Sansom, S. C.

  National Institutes of Health

  9/20/11 → 8/31/16

  Project: Research project

  • Hyperkalemia 100%
  • Recycling 92%
  • Nephrons 91%
  • Kidney 89%
  • Aldosterone 83%

• Response-Selective C5a Agonist for the Treatment of Asthma

  Poole, J. A.

  National Institutes of Health

  9/21/11 → 12/31/13

  Project: Research project

  • Anaphylatoxin C5a Receptor 100%
  • Asthma 82%
  • Allergens 24%
  • Therapeutics 18%
  • Cytokines 16%

• Role of Histone H2B Ubiquitylation in DNA Replication

  Trujillo, K. M.

  National Institutes of Health

  9/21/11 → 2/28/15

  Project: Research project

  • Ubiquitination 100%
  • DNA Replication 98%
  • Nucleosomes 88%
  • Histones 77%
  • S Phase 74%

• Temporally controlled oncogene expression in a novel pancreatic cancer model

  Wagner, K.

  National Institutes of Health

  9/22/11 → 8/31/14

  Project: Research project

  • pancreatic neoplasms 100%
  • oncogenes 85%
  • neoplasms 56%
  • adenocarcinoma 36%
  • neoplasm cells 35%

• Pancreatic Tumor Micro-environment Network

  Singh, R. K., Batra, S. K., Hollingsworth, T. & Johnson, K. R.

  National Institutes of Health

  9/26/11 → 7/31/16

  Project: Research project

  • Tumor Microenvironment 100%
  • Pancreatic Neoplasms 96%
  • Neoplasm Metastasis 37%
  • Hedgehog Proteins 36%
  • Cadherins 34%

• Molecular Mechanisms &Therapy for Cocaine Abuse in HAND

  Buch, S. J.

  National Institutes of Health

  9/30/11 → 7/31/14

  Project: Research project

  • Cocaine 100%
  • Cocaine-Related Disorders 95%
  • HIV-1 89%
  • Nervous System Diseases 81%
  • Platelet-Derived Growth Factor 75%

• Alcohol consumption and RSV infection in airway injury

  Wyatt, T. A.

  National Institutes of Health

  10/1/11 → 9/30/15

  Project: Research project

  • Respiratory Syncytial Virus Infections 100%
  • Alcohol Drinking 68%
  • Alcohols 68%
  • Cilia 66%
  • Virus Diseases 50%

• Glycosyltransferase Golgi Retention Mechanism

  Cheng, P.

  National Institutes of Health

  10/1/11 → 9/30/15

  Project: Research project

  • Glycosyltransferases 100%
  • Mucins 85%
  • Polysaccharides 65%
  • Veterans 24%
  • Lung Neoplasms 23%

• PDGF-BB Reverses Impaired Neurogenesis Mediated by Tat and Cocaine

  Buch, S. J., Honghong, Y. & Hu, G.

  National Institutes of Health

  1/15/12 → 12/31/16

  Project: Research project

  • Becaplermin 100%
  • Proto-Oncogene Proteins c-sis 96%
  • Neurogenesis 95%
  • Cocaine 90%
  • Human Immunodeficiency Virus Proteins 50%

• UNMC Summer Undergraduate Alcohol Research Program

  Klassen, L. W., Romberger, D., Mikuls, T. R., Klassen, L. W. & Bailey, K. L.

  National Institutes of Health

  2/5/12 → 1/31/17

  Project: Research project

  • alcohol 100%
  • student 32%
  • career 27%
  • biomedical research 23%
  • minority 20%

• Escape From Broadly Neutralizing MAbs by Genetically-Linked Early & Late HIV Envs

  Byrareddy, S.

  National Institutes of Health

  2/6/12 → 1/31/15

  Project: Research project

  • Broadly Neutralizing Antibodies 100%
  • HIV 83%
  • Viruses 47%
  • Mutation 29%
  • Immunity 28%

• HIV Genetic Diversity and Viral Neuropathogenesis

  Kanmogne, G. D.

  National Institutes of Health

  2/14/12 → 12/31/16

  Project: Research project

  • Genetic Variation 100%
  • HIV 82%
  • Neurocognitive Disorders 45%
  • HIV-1 39%
  • Genotype 17%

• Mechanisms of Motor Skill Learning in the Fragile X Mouse Model

  Dunaevsky, A.

  National Institutes of Health

  3/15/12 → 2/28/17

  Project: Research project

  • Fragile X Syndrome 100%
  • Motor Skills 96%
  • Learning 64%
  • Motor Cortex 40%
  • Neuronal Plasticity 25%

• Heart Camp: Promoting Adherence to Exercise in Patients with Heart Failure

  Pozehl, B.

  National Institutes of Health

  4/1/12 → 3/31/17

  Project: Research project

  • Heart Failure 100%
  • Exercise 94%
  • Heart 81%
  • Motivation 12%
  • Resistance Training 11%

• Novel Effectors of Colon Tumorigenesis

  Lewis, R. E.

  National Institutes of Health

  4/12/12 → 3/31/17

  Project: Research project

  • KSR-1 protein kinase 100%
  • Colon 40%
  • Carcinogenesis 37%
  • Neoplasms 15%
  • ras Proteins 11%

• The reach and effectiveness of technology-enhanced diabetes prevention programs

  Almeida, F.

  National Institutes of Health

  5/1/12 → 4/30/17

  Project: Research project

  • Weight Loss 100%
  • Technology 98%
  • Costs and Cost Analysis 44%
  • Life Style 42%
  • Feeding Behavior 39%

• 2012 International Conference on Gram-positive Pathogens

  Fey, P. D.

  National Institutes of Health

  6/1/12 → 5/31/13

  Project: Research project

  • Research Personnel 100%
  • Enterococcus faecium 94%
  • Foster Home Care 88%
  • Streptococcus pyogenes 87%
  • Clostridium difficile 85%

• Effect of Alcohol on Hepatic Creatine Biosynthesis: Role of Defective Methylation

  Kharbanda, K.

  National Institutes of Health

  7/1/12 → 6/30/16

  Project: Research project

  • creatine 100%
  • methylation 61%
  • alcohols 55%
  • liver 47%
  • biosynthesis 43%

• Cytokine receptor populations in human autoimmune diabetes

  Sarvetnick, N. E.

  National Institutes of Health

  7/1/12 → 6/30/17

  Project: Research project

  • Interleukin-18 Receptors 100%
  • Cytokine Receptors 61%
  • Type 1 Diabetes Mellitus 52%
  • Clinical Trials 25%
  • Population 23%

• Targeting MUC4 for chemosensitization of pancreatic cancer

  Batra, S. K.

  National Institutes of Health

  7/9/12 → 6/30/15

  Project: Research project

  • Pancreatic Neoplasms 100%
  • Fluticasone 57%
  • gemcitabine 36%
  • Down-Regulation 20%
  • Glucocorticoids 17%

• Effect of Beta-secretase Inhibitors on Pancreatic Cancer Cells

  Solheim, J. C.

  National Institutes of Health

  7/11/12 → 6/30/15

  Project: Research project

  • Amyloid Precursor Protein Secretases 100%
  • Amyloid beta-Protein Precursor 88%
  • Pancreatic Neoplasms 78%
  • Cell Survival 14%
  • Alzheimer Disease 9%

• Microglial ion channels and HIV-1-associated dementia

  Xiong, H.

  National Institutes of Health

  8/1/12 → 4/30/17

  Project: Research project

  • Microglia 100%
  • Ion Channels 83%
  • HIV-1 80%
  • Dementia 69%
  • Neurocognitive Disorders 37%

• Accumulation of VH replacement products in HIV patients

  Zhang, Z.

  National Institutes of Health

  8/1/12 → 7/31/14

  Project: Research project

  • HIV 100%
  • B-Lymphoid Precursor Cells 51%
  • Neutralizing Antibodies 43%
  • HIV Antigens 32%
  • Antibodies 29%

• Increasing the Antischistosomal Selectivity of Aryl Hydantoins

  Vennerstrom, J. L.

  National Institutes of Health

  8/15/12 → 7/31/15

  Project: Research project

  • Hydantoins 100%
  • Androgen Receptors 86%
  • Antischistosomal 69%
  • Schistosomiasis 52%
  • Hydantoin 52%

• Global Genomic and Proteomic Profiling of African Children with Typhoid Fever

  Obaro, S. K.

  National Institutes of Health

  8/17/12 → 7/31/16

  Project: Research project

  • Typhoid Fever 100%
  • Proteomics 61%
  • Child 29%
  • Serogroup 17%
  • Vaccines 17%

• Mechanisms of selective glycolytic inhibition in ischemic kidney proximal tubles

  Padanilam, B. J.

  National Institutes of Health

  9/14/12 → 8/31/14

  Project: Research project

  • Poly (ADP-Ribose) Polymerase-1 100%
  • Wounds and Injuries 70%
  • Apoptosis 66%
  • Adenosine Triphosphate 65%
  • Kidney 64%

• Targeting MUC1-induced Tumor-stromal Metabolic Cross-talk in Pancreatic Cancer

  Singh, P.

  National Institutes of Health

  9/25/12 → 7/31/17

  Project: Research project

  • Pancreatic Neoplasms 100%
  • Neoplasms 35%
  • Neoplasm Metastasis 21%
  • Adenocarcinoma 13%
  • Glycolysis 11%

• Induced Pluripotent Stem Cell Approach to Glaucomatous Optic Neuropathy

  Ahmad, I.

  National Institutes of Health

  12/1/12 → 11/30/16

  Project: Research project

  • Retinal Ganglion Cells 100%
  • Induced Pluripotent Stem Cells 96%
  • Optic Nerve Diseases 91%
  • Cell- and Tissue-Based Therapy 16%
  • Nucleic Acids 11%

• Flt3L Treatment of Pancreatic Cancer

  Solheim, J. C.

  National Institutes of Health

  1/1/13 → 12/31/15

  Project: Research project

  • pancreatic neoplasms 100%
  • neoplasms 49%
  • dendritic cells 28%
  • therapeutics 22%
  • natural killer cells 17%

• Dan River Region POPS: Partnerning for Obesity Planning and Sustainability

  Estabrooks, P. A.

  National Institutes of Health

  1/1/13 → 11/30/16

  Project: Research project

  • obesity 100%
  • sustainability 50%
  • planning 40%
  • river 34%
  • youth 13%

• Inflammation, miRNA and autophagy in diabetes

  Mishra, P. K.

  National Institutes of Health

  1/7/13 → 7/31/18

  Project: Research project

  • Matrix Metalloproteinase 9 100%
  • Autophagy 85%
  • MicroRNAs 65%
  • Inflammation 48%
  • Interleukin-10 17%

• Opiate induced SIV-Neuropathogenesis: Role of miRNA-29b in the Periphery-CNS Cro

  Buch, S. J.

  National Institutes of Health

  2/1/13 → 1/31/18

  Project: Research project

  • Opiate Alkaloids 100%
  • MicroRNAs 95%
  • Morphine 80%
  • Opioid-Related Disorders 30%
  • Macaca 27%

• Leveraging RC-12 for Radical Cure of Plasmodium Vivax

  Vennerstrom, J. L.

  National Institutes of Health

  2/1/13 → 1/31/16

  Project: Research project

  • Plasmodium vivax 100%
  • malaria 54%
  • exoerythrocytic stage 47%
  • metabolites 44%
  • pharmacokinetics 39%

• Development of Theranostic Ultrasound

  Porter, T. R.

  National Institutes of Health

  2/1/13 → 1/31/16

  Project: Research project

  • Theranostic Nanomedicine 100%
  • Microbubbles 96%
  • Thrombosis 38%
  • Acoustics 25%
  • Microvessels 25%

• Early Detection and Intervention of Orthopedic Implant Loosening using Polymer Th

  Wang, D.

  National Institutes of Health

  3/1/13 → 2/28/17

  Project: Research project

  • Theranostic Nanomedicine 100%
  • N-(2-hydroxypropyl)methacrylamide 64%
  • Orthopedics 64%
  • Polymers 62%
  • Osteolysis 30%

• Neuronanomedicine

  Gendelman, H. E.

  National Institutes of Health

  3/15/13 → 3/14/14

  Project: Research project

  • Nanomedicine 100%
  • Nanotechnology 93%
  • Congresses 51%
  • Intellectual Property 40%
  • Bioethics 36%

• Targeting the CXCL12/CXCR4 Axis towards the Therapy of Metastatic Cancers

  Li, R.

  National Institutes of Health

  4/1/13 → 3/31/16

  Project: Research project

  • Chemokine CXCL12 100%
  • Chemokine Receptor CXCR4 Antagonist 98%
  • Efficiency 68%
  • Ligands 66%
  • Two-Dimensional NMR 57%

• Human DNA Replication Machines: Structure-Function of Polymerase Alpha-Primase

  Tahirov, T. H.

  National Institutes of Health

  4/1/13 → 3/31/17

  Project: Research project

  • DNA Primase 100%
  • DNA Replication 55%
  • RNA primers 31%
  • DNA-Directed DNA Polymerase 12%
  • Genomic Instability 11%