University of Nebraska Medical Center

Projects

Projects per year 1974 1985 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2021

• 15 Active
• 689 Finished
• 1583 Not started

Projects per year

Search results

• Development of Gallium-Based Therapies for Pulmonary Mycobacterial Infections

  Britigan, B. E.

  National Institutes of Health

  10/1/14 → 9/30/18

  Project: Research project

  • Mycobacterium tuberculosis 100%
  • Gallium 99%
  • Tuberculosis 69%
  • Pulmonary Tuberculosis 58%
  • Lung 41%

• Elucidating the role of exosomal miR-21 in SIV/HIV neurological dysfunction

  Fox, H. S. & Yelamanchili, S.

  National Institutes of Health

  1/15/15 → 12/31/16

  Project: Research project

  • HIV-1 100%
  • Exosomes 96%
  • HIV 82%
  • HIV Infections 72%
  • MicroRNAs 69%

• Neuropilin-2 Axis in Docetaxel Resistance and Prostate Cancer Bone Metastasis

  Datta, K.

  National Institutes of Health

  2/1/15 → 1/31/20

  Project: Research project

  • Neuropilin-2 100%
  • Bone Neoplasms 58%
  • Docetaxel 49%
  • Prostatic Neoplasms 48%
  • Neoplasm Metastasis 31%

• Optimization of Antischistosomal Chemotypes

  Vennerstrom, J. L.

  National Institutes of Health

  2/1/15 → 1/31/20

  Project: Research project

  • Hydantoins 100%
  • Schistosomiasis 98%
  • 1,2,4-trioxane 78%
  • Carboxylic Acids 53%
  • Pharmaceutical Preparations 51%

• Nanoparticles based on histone deacetylase inhibitors for combination treatments

  Oupicky, D.

  National Institutes of Health

  4/1/15 → 3/31/17

  Project: Research project

  • Histone Deacetylase Inhibitors 100%
  • Nanoparticles 58%
  • Histone Deacetylases 35%
  • Pharmaceutical Preparations 34%
  • Lung Neoplasms 32%

• Research and Development of Novel Drug Delivery Systems Symposium

  Mahato, R. I.

  National Institutes of Health

  4/1/15 → 3/31/16

  Project: Research project

  • Congresses 100%
  • Drug Delivery Systems 74%
  • Pharmaceutical Preparations 52%
  • Financial Support 33%
  • Posters 32%

• Dual-function nanoparticles for oral treatment of inflammatory bowel disease

  Oupicky, D.

  National Institutes of Health

  4/15/15 → 1/31/17

  Project: Research project

  • Inflammatory Bowel Diseases 100%
  • Nanoparticles 65%
  • Inflammation 30%
  • Therapeutics 16%
  • Anti-Inflammatory Agents 15%

• MIC-1 and its functional partners in prostate cancer racial disparity

  Batra, S. K.

  National Institutes of Health

  5/1/15 → 4/30/20

  Project: Research project

  • African Americans 100%
  • Prostatic Neoplasms 87%
  • Docetaxel 35%
  • Prostate Cancer, Hereditary, 7 16%
  • Anticarcinogenic Agents 15%

• Transmitted/Founder SHIV macaque model

  Byrareddy, S.

  National Institutes of Health

  7/1/15 → 6/30/17

  Project: Research project

  • Macaca 100%
  • Viruses 77%
  • Vaccines 36%
  • Rwanda 16%
  • Zambia 15%

• PDGF-CC Mediated Reversal of Synaptodendritic Injury in HAND

  Buch, S. J.

  National Institutes of Health

  7/3/15 → 5/31/20

  Project: Research project

  • Neurocognitive Disorders 100%
  • Platelet-Derived Growth Factor 81%
  • HIV 55%
  • Wounds and Injuries 29%
  • platelet-derived growth factor C 25%

• IGF-II-Based Approach to Therapy for Pancreatic Cancer

  MacDonald, R. G.

  National Institutes of Health

  7/14/15 → 6/30/17

  Project: Research project

  • Insulin-Like Growth Factor II 100%
  • Pancreatic Neoplasms 64%
  • Ligands 27%
  • Neoplasms 16%
  • Somatomedins 13%

• Polymeric Nanomedicines of Hedgehog Inhibitor and miRNA for Treating Pancreatic Cancer

  Mahato, R. I. & Batra, S. K.

  National Institutes of Health

  7/15/15 → 3/31/19

  Project: Research project

  • HhAntag691 100%
  • Hedgehogs 68%
  • Nanomedicine 61%
  • Pancreatic Neoplasms 49%
  • MicroRNAs 36%

• Evaluating the PKC Enzyme System in Human Colon Cancer

  Black, J. D.

  National Institutes of Health

  7/16/15 → 6/30/17

  Project: Research project

  • Protein Kinase C 100%
  • Colorectal Neoplasms 75%
  • Colonic Neoplasms 68%
  • Isoenzymes 60%
  • Enzymes 44%

• Targeted Radiation Therapy for Pancreatic Cancer

  Batra, S. K. & Jain, M.

  National Institutes of Health

  7/17/15 → 6/30/20

  Project: Research project

  • Pancreatic Neoplasms 100%
  • Radiotherapy 50%
  • Tumor Microenvironment 49%
  • Radiopharmaceuticals 46%
  • Radioisotopes 39%

• Ramipril treatment of claudication: oxidative damage and muscle fibrosis

  Pipinos, I. I. & Casale, G. P.

  National Institutes of Health

  8/1/15 → 3/31/20

  Project: Research project

  • Ramipril 100%
  • Peripheral Arterial Disease 66%
  • Fibrosis 38%
  • Muscular Diseases 36%
  • Muscles 34%

• HIV Tat & Morphine induce mircroglial migration & activation via release of miR-9 & 138

  Buch, S. J. & Fox, H. S.

  National Institutes of Health

  8/1/15 → 5/31/20

  Project: Research project

  • Morphine 100%
  • MicroRNAs 82%
  • HIV 64%
  • Opioid-Related Disorders 53%
  • Extracellular Vesicles 51%

• Maternal Immune Activation in a Genetic Mouse Model of ASD

  Dunaevsky, A.

  National Institutes of Health

  8/1/15 → 5/31/19

  Project: Research project

  • Autism Spectrum Disorder 100%
  • Genetic Models 76%
  • Mothers 55%
  • Rett Syndrome 20%
  • Maternal Exposure 19%

• Exome screening and directed breeding of rhesus for human genetic disease models

  Norgren, R. B. & Johnson, R. P.

  National Institutes of Health

  8/1/15 → 7/31/17

  Project: Research project

  • genetic disorders 100%
  • disease models 97%
  • loss-of-function mutation 84%
  • Macaca mulatta 84%
  • genetic models 82%

• Targeted Core Shell Nanogels for Triple Negative Breast Cancer

  Kabanov, A., Rihe, L. & Bronich, T. K.

  National Institutes of Health

  8/14/15 → 7/31/20

  Project: Research project

  • Nanogels 100%
  • Triple Negative Breast Neoplasms 72%
  • Neoplasms 20%
  • Pharmaceutical Preparations 15%
  • Nanotechnology 12%

• Preventing relapse of destructive behavior using behavioral momentum theory

  Fisher, W. W.

  National Institutes of Health

  8/18/15 → 4/30/20

  Project: Research project

  • relapse 100%
  • communication 52%
  • functional analysis 28%
  • caregiver 18%
  • epidemiological studies 12%

• Eunice Kennedy Shriver Intellectual and Developmental Disabilities Research Center at Vanderbilt University

  Mirnics, K.

  National Institutes of Health

  9/17/15 → 5/31/20

  Project: Research project

  • neurophysiology 100%
  • Developmental Disabilities 50%
  • Intellectual Disability 37%
  • instrumentation 28%
  • phenotype 27%

• Sensorimotor Learning in Children with Cerebral Palsy

  Kurz, M. J.

  National Institutes of Health

  9/24/15 → 6/30/19

  Project: Research project

  • Cerebral Palsy 100%
  • Learning 60%
  • Child 42%
  • Motor Skills 33%
  • Magnetoencephalography 24%

• The Role of Astrocytic signaling in Synaptic Plasticity

  Dunaevsky, A.

  National Institutes of Health

  9/25/15 → 7/31/17

  Project: Research project

  • Astrocytes 75%
  • Neuronal Plasticity 61%
  • Learning 60%
  • Calcium Signaling 32%
  • Neurodevelopmental Disorders 32%

• Humanized Mice as a Tool to Monitor HIV Brain Reservoirs and Effects of Substance Abuse

  Gorantla, S., Poluektova, L. Y., Gorantla, S. & Poluektova, L. Y.

  National Institutes of Health

  9/30/15 → 7/31/18

  Project: Research project

  • Substance-Related Disorders 100%
  • HIV 84%
  • Brain 59%
  • Astrocytes 48%
  • Neuroglia 46%

• Cardiac Sympathetic Afferent Denervation and Remodeling in Heart Failure

  Zucker, I. H., Wang, H. & Wang, H.

  National Institutes of Health

  12/18/15 → 11/30/19

  Project: Research project

  • Reflex 100%
  • Sympathectomy 79%
  • Heart Failure 75%
  • Myocardial Infarction 69%
  • Autonomic Agents 24%

• Novel Mechanisms of Cervical Cancer Development and Progression

  Wang, C.

  National Institutes of Health

  1/21/16 → 12/31/20

  Project: Research project

  • Uterine Cervical Neoplasms 100%
  • Carcinogenesis 19%
  • Oncogene Proteins 19%
  • Nude Mice 16%
  • Neoplasms 14%

• EP67-Based Targeted Mucosal Vaccines to Prevent Primary Infection with CMV

  Vetro, J. A.

  National Institutes of Health

  2/1/16 → 1/31/21

  Project: Research project

  • Cytomegalovirus 100%
  • Mucosal Immunity 83%
  • Vaccines 66%
  • Intranasal Administration 56%
  • Infections 53%

• APOBEC3-Nucleic Acid Interactions and Molecular Mechanisms of HIV Restriction

  Lyubchenko, Y. L.

  National Institutes of Health

  3/2/16 → 1/31/20

  Project: Research project

  • Nucleic Acids 100%
  • Deamination 80%
  • Single-Stranded DNA 73%
  • HIV 69%
  • Virion 58%

• Role of Claudin-2 in Colon Tumorigenesis

  Singh, A. B.

  National Institutes of Health

  4/1/16 → 3/31/20

  Project: Research project

  • Claudin-2 100%
  • Colon 29%
  • Carcinogenesis 26%
  • Colorectal Neoplasms 25%
  • Cell Plasticity 11%

• Phosphorylation and gating of cardiac connexin channels

  Sorgen, P. L.

  National Institutes of Health

  4/1/16 → 1/31/20

  Project: Research project

  • Connexin 43 100%
  • Gap Junctions 62%
  • Connexins 55%
  • Phosphorylation 44%
  • Peptidomimetics 19%

• Accelerating Access: Health Science Education in Native American Communities

  Godfrey, M.

  National Institutes of Health

  4/1/16 → 1/31/21

  Project: Research project

  • health science 100%
  • health 54%
  • career 38%
  • student 34%
  • education 33%

• The Lymphoid Tissue Pharmacology of Antiretroviral Drugs

  Fletcher, C. V.

  National Institutes of Health

  4/7/16 → 3/31/21

  Project: Research project

  • Lymphoid Tissue 100%
  • Lymph Nodes 52%
  • Viruses 49%
  • Pharmacology 49%
  • Viremia 41%

• The Hippo/YAP Signaling Pathway in Ovarian High Grade Serous Carcinoma

  Wang, C.

  National Institutes of Health

  5/1/16 → 4/30/21

  Project: Research project

  • Fallopian Tubes 100%
  • Carcinoma 53%
  • Ovary 44%
  • Epithelial Cells 32%
  • Ovarian Epithelial Carcinoma 22%

• Rac1 GTPase in tumorigenesis and progression of pancreatic cancer

  Ouellette, M. M. & Batra, S. K.

  National Institutes of Health

  5/1/16 → 4/30/21

  Project: Research project

  • Pancreatic Neoplasms 100%
  • GTP Phosphohydrolases 71%
  • Carcinogenesis 47%
  • ras Genes 24%
  • rac1 GTP-Binding Protein 16%

• Development of Quinoxaline Based IKKbeta Inhibitors for Kras Driven Cancers

  Natarajan, A.

  National Institutes of Health

  5/9/16 → 4/30/21

  Project: Research project

  • Quinoxalines 100%
  • Adenocarcinoma 50%
  • Adenosine Triphosphate 50%
  • Mutation 48%
  • Neoplasms 37%

• Validation of biomarkers for early diagnosis and risk prediction of pancreatic neoplasms

  Batra, S. K.

  National Institutes of Health

  5/17/16 → 3/31/21

  Project: Research project

  • Pancreatic Neoplasms 100%
  • Biomarkers 71%
  • Early Diagnosis 70%
  • Cysts 39%
  • Pancreatic Diseases 29%

• The molecular control of bacterial programmed cell death

  Bayles, K. W.

  National Institutes of Health

  5/24/16 → 4/30/21

  Project: Research project

  • cell death 100%
  • programmed cell death 70%
  • autolysis 21%
  • biochemical mechanisms 21%
  • peptidoglycans 19%

• Nanomedicine Development for Systemic Lupus Erythematosus

  Wang, D.

  National Institutes of Health

  5/26/16 → 4/30/21

  Project: Research project

  • Polyethylene Glycols 100%
  • Nanomedicine 85%
  • Micelles 53%
  • Systemic Lupus Erythematosus 46%
  • Glucocorticoids 32%

• FASEB SRC on Translational Neuroimmunology: From Mechanisms to Therapeutics

  Kielian, T. L.

  National Institutes of Health

  6/1/16 → 5/31/17

  Project: Research project

  • therapeutics 100%
  • graduate students 63%
  • resorts 61%

• Development of nucleic acid delivery platform based on polymeric CXCR4 antagonists

  Oupicky, D.

  National Institutes of Health

  6/15/16 → 6/14/17

  Project: Research project

  • Cholangiocarcinoma 100%
  • Nucleic Acids 85%
  • MicroRNAs 58%
  • Nanoparticles 46%
  • CXCR4 Receptors 23%

• Cell biological mechanisms that regulate development of cartilage architecture

  Dudley, A. T.

  National Institutes of Health

  6/20/16 → 5/31/21

  Project: Research project

  • Cartilage 100%
  • Enchondromatosis 43%
  • Chondrocytes 39%
  • Growth Plate 23%
  • Bone and Bones 17%

• Host-Directed Immunotherapy: A One Health Approach

  Sanderson, S. & Vetro, J. A.

  National Institutes of Health

  7/7/16 → 6/30/21

  Project: Research project

  • One Health 100%
  • Immunotherapy 65%
  • Anti-Bacterial Agents 61%
  • Innate Immunity 51%
  • Anaphylatoxin C5a Receptor 28%

• Research and Development of Nucleic Acid based Nanomedicines

  Mahato, R. I.

  National Institutes of Health

  7/15/16 → 6/30/17

  Project: Research project

  • Nucleic Acids 100%
  • Nanomedicine 73%
  • fomivirsen 60%
  • pegaptanib 52%
  • Genetic Therapy 29%

• Mechanistic insights into Juvenile Neuronal Ceroid Lipofuscinosis using targeted gene delivery

  Kielian, T. L.

  National Institutes of Health

  8/1/16 → 7/31/17

  Project: Research project

  • Neuronal Ceroid-Lipofuscinoses 100%
  • Astrocytes 68%
  • Neurons 39%
  • Methyl-CpG-Binding Protein 2 27%
  • Mutation 20%

• The impact of marijuana use on brain and cognitive function in HIV-infected patients

  Wilson, T. W.

  National Institutes of Health

  8/1/16 → 7/31/18

  Project: Research project

  • Marijuana Use 100%
  • HIV 91%
  • Cognition 60%
  • Acquired Immunodeficiency Syndrome 53%
  • Substance-Related Disorders 46%

• The combinatorial effects of Opiates and the emerging promoter-variant strains of HIV-1 subtype C on HIV neuropathogensis and latency

  Buch, S. J. & Byrareddy, S.

  National Institutes of Health

  8/15/16 → 7/31/21

  Project: Research project

  • Opiate Alkaloids 100%
  • India 72%
  • Viruses 68%
  • HIV 56%
  • Cercopithecine Herpesvirus 1 55%

• Great Plains IDeA-CTR

  Mikuls, T. R., Rizzo, M., Fox, H. S., Klassen, L. W., Cramer, M. E., Meza, J. L. & Estabrooks, P. A.

  National Institutes of Health

  9/1/16 → 6/30/21

  Project: Research project

  • translational medical research 100%
  • mentoring 99%
  • biostatistics 84%
  • professional development 58%
  • education 32%

• Macrophage, Meth, HIV and Histones: An Interplay

  Ciborowski, P. S. & Fox, H. S.

  National Institutes of Health

  9/1/16 → 6/30/21

  Project: Research project

  • Methamphetamine 100%
  • HIV Infections 60%
  • Macrophages 51%
  • Histones 44%
  • HIV 43%

• HIV Tat & cocaine-mediated alterations in microglial migration & activation involve epigenetic reulation of miRNAs

  Buch, S. J., Guo, M. & Hu, G.

  National Institutes of Health

  9/1/16 → 5/31/21

  Project: Research project

  • Cocaine 100%
  • HIV 74%
  • MicroRNAs 64%
  • Epigenomics 60%
  • Monocyte Chemoattractant Proteins 54%

• Development of Chol-DsiRNA Polyplexes to Improve the Therapy of Breast Cancer

  Vetro, J. A.

  National Institutes of Health

  9/15/16 → 8/31/17

  Project: Research project

  • small interfering RNA 100%
  • breast neoplasms 78%
  • therapeutics 37%
  • RNA interference 24%
  • metastasis 17%