University of Nebraska Medical Center

Projects

Projects per year 1974 2021

• 18 Active
• 345 Not started
• 686 Finished

Projects per year

Search results

• Finished

  Glutaminase and its neurotoxic link to HAND

  Zheng, J. C.

  National Institutes of Health

  9/30/16 → 5/31/20

  Project: Research project

  • Glutaminase 100%
  • Neurocognitive Disorders 84%
  • HIV 44%
  • HIV-1 19%
  • Microglia 16%

• Mucociliary clearance in aging

  Bailey, K. L.

  National Institutes of Health

  9/30/16 → 4/30/21

  Project: Research project

  • Protein Kinase C-epsilon 100%
  • Mucociliary Clearance 73%
  • DNA Breaks 33%
  • Double-Stranded DNA Breaks 31%
  • Pneumonia 22%

• Comprehensive Structural and Functional Mapping of the Mammalian Cardiac Nervous System

  Zucker, I. H.

  National Institutes of Health

  9/24/16 → 7/31/19

  Project: Research project

  • Nervous System 100%
  • Autonomic Nervous System 54%
  • Sudden Cardiac Death 53%
  • Cell Body 49%
  • Ganglia 47%

• Development of Chol-DsiRNA Polyplexes to Improve the Therapy of Breast Cancer

  Vetro, J. A.

  National Institutes of Health

  9/15/16 → 8/31/17

  Project: Research project

  • small interfering RNA 100%
  • breast neoplasms 78%
  • therapeutics 37%
  • RNA interference 24%
  • metastasis 17%

• Great Plains IDeA-CTR

  Mikuls, T. R., Rizzo, M., Fox, H. S., Klassen, L. W., Cramer, M. E., Meza, J. L. & Estabrooks, P. A.

  National Institutes of Health

  9/1/16 → 6/30/21

  Project: Research project

  • translational medical research 100%
  • mentoring 99%
  • biostatistics 84%
  • professional development 58%
  • education 32%

• Macrophage, Meth, HIV and Histones: An Interplay

  Ciborowski, P. S. & Fox, H. S.

  National Institutes of Health

  9/1/16 → 6/30/21

  Project: Research project

  • Methamphetamine 100%
  • HIV Infections 60%
  • Macrophages 51%
  • Histones 44%
  • HIV 43%

• HIV Tat & cocaine-mediated alterations in microglial migration & activation involve epigenetic reulation of miRNAs

  Buch, S. J., Guo, M. & Hu, G.

  National Institutes of Health

  9/1/16 → 5/31/21

  Project: Research project

  • Cocaine 100%
  • HIV 74%
  • MicroRNAs 64%
  • Epigenomics 60%
  • Monocyte Chemoattractant Proteins 54%

• The combinatorial effects of Opiates and the emerging promoter-variant strains of HIV-1 subtype C on HIV neuropathogensis and latency

  Buch, S. J. & Byrareddy, S.

  National Institutes of Health

  8/15/16 → 7/31/21

  Project: Research project

  • Opiate Alkaloids 100%
  • India 72%
  • Viruses 68%
  • HIV 56%
  • Cercopithecine Herpesvirus 1 55%

• The impact of marijuana use on brain and cognitive function in HIV-infected patients

  Wilson, T. W.

  National Institutes of Health

  8/1/16 → 7/31/18

  Project: Research project

  • Marijuana Use 100%
  • HIV 91%
  • Cognition 60%
  • Acquired Immunodeficiency Syndrome 53%
  • Substance-Related Disorders 46%

• Mechanistic insights into Juvenile Neuronal Ceroid Lipofuscinosis using targeted gene delivery

  Kielian, T. L.

  National Institutes of Health

  8/1/16 → 7/31/17

  Project: Research project

  • Neuronal Ceroid-Lipofuscinoses 100%
  • Astrocytes 68%
  • Neurons 39%
  • Methyl-CpG-Binding Protein 2 27%
  • Mutation 20%

• Research and Development of Nucleic Acid based Nanomedicines

  Mahato, R. I.

  National Institutes of Health

  7/15/16 → 6/30/17

  Project: Research project

  • Nucleic Acids 100%
  • Nanomedicine 73%
  • fomivirsen 60%
  • pegaptanib 52%
  • Genetic Therapy 29%

• Host-Directed Immunotherapy: A One Health Approach

  Sanderson, S. & Vetro, J. A.

  National Institutes of Health

  7/7/16 → 6/30/21

  Project: Research project

  • One Health 100%
  • Immunotherapy 65%
  • Anti-Bacterial Agents 61%
  • Innate Immunity 51%
  • Anaphylatoxin C5a Receptor 28%

• Cell biological mechanisms that regulate development of cartilage architecture

  Dudley, A. T.

  National Institutes of Health

  6/20/16 → 5/31/21

  Project: Research project

  • Cartilage 100%
  • Enchondromatosis 43%
  • Chondrocytes 39%
  • Growth Plate 23%
  • Bone and Bones 17%

• Development of nucleic acid delivery platform based on polymeric CXCR4 antagonists

  Oupicky, D.

  National Institutes of Health

  6/15/16 → 6/14/17

  Project: Research project

  • Cholangiocarcinoma 100%
  • Nucleic Acids 85%
  • MicroRNAs 58%
  • Nanoparticles 46%
  • CXCR4 Receptors 23%

• FASEB SRC on Translational Neuroimmunology: From Mechanisms to Therapeutics

  Kielian, T. L.

  National Institutes of Health

  6/1/16 → 5/31/17

  Project: Research project

  • therapeutics 100%
  • graduate students 63%
  • resorts 61%

• Nanomedicine Development for Systemic Lupus Erythematosus

  Wang, D.

  National Institutes of Health

  5/26/16 → 4/30/21

  Project: Research project

  • Polyethylene Glycols 100%
  • Nanomedicine 85%
  • Micelles 53%
  • Systemic Lupus Erythematosus 46%
  • Glucocorticoids 32%

• The molecular control of bacterial programmed cell death

  Bayles, K. W.

  National Institutes of Health

  5/24/16 → 4/30/21

  Project: Research project

  • cell death 100%
  • programmed cell death 70%
  • autolysis 21%
  • biochemical mechanisms 21%
  • peptidoglycans 19%

• Validation of biomarkers for early diagnosis and risk prediction of pancreatic neoplasms

  Batra, S. K.

  National Institutes of Health

  5/17/16 → 3/31/21

  Project: Research project

  • Pancreatic Neoplasms 100%
  • Biomarkers 71%
  • Early Diagnosis 70%
  • Cysts 39%
  • Pancreatic Diseases 29%

• Development of Quinoxaline Based IKKbeta Inhibitors for Kras Driven Cancers

  Natarajan, A.

  National Institutes of Health

  5/9/16 → 4/30/21

  Project: Research project

  • Quinoxalines 100%
  • Adenocarcinoma 50%
  • Adenosine Triphosphate 50%
  • Mutation 48%
  • Neoplasms 37%

• Rac1 GTPase in tumorigenesis and progression of pancreatic cancer

  Ouellette, M. M. & Batra, S. K.

  National Institutes of Health

  5/1/16 → 4/30/21

  Project: Research project

  • Pancreatic Neoplasms 100%
  • GTP Phosphohydrolases 71%
  • Carcinogenesis 47%
  • ras Genes 24%
  • rac1 GTP-Binding Protein 16%

• The Hippo/YAP Signaling Pathway in Ovarian High Grade Serous Carcinoma

  Wang, C.

  National Institutes of Health

  5/1/16 → 4/30/21

  Project: Research project

  • Fallopian Tubes 100%
  • Carcinoma 53%
  • Ovary 44%
  • Epithelial Cells 32%
  • Ovarian Epithelial Carcinoma 22%

• The Lymphoid Tissue Pharmacology of Antiretroviral Drugs

  Fletcher, C. V.

  National Institutes of Health

  4/7/16 → 3/31/21

  Project: Research project

  • Lymphoid Tissue 100%
  • Lymph Nodes 52%
  • Viruses 49%
  • Pharmacology 49%
  • Viremia 41%

• Accelerating Access: Health Science Education in Native American Communities

  Godfrey, M.

  National Institutes of Health

  4/1/16 → 1/31/21

  Project: Research project

  • health science 100%
  • health 54%
  • career 38%
  • student 34%
  • education 33%

• Role of Claudin-2 in Colon Tumorigenesis

  Singh, A. B.

  National Institutes of Health

  4/1/16 → 3/31/20

  Project: Research project

  • Claudin-2 100%
  • Colon 29%
  • Carcinogenesis 26%
  • Colorectal Neoplasms 25%
  • Cell Plasticity 11%

• Phosphorylation and gating of cardiac connexin channels

  Sorgen, P. L.

  National Institutes of Health

  4/1/16 → 1/31/20

  Project: Research project

  • Connexin 43 100%
  • Gap Junctions 62%
  • Connexins 55%
  • Phosphorylation 44%
  • Peptidomimetics 19%

• APOBEC3-Nucleic Acid Interactions and Molecular Mechanisms of HIV Restriction

  Lyubchenko, Y. L.

  National Institutes of Health

  3/2/16 → 1/31/20

  Project: Research project

  • Nucleic Acids 100%
  • Deamination 80%
  • Single-Stranded DNA 73%
  • HIV 69%
  • Virion 58%

• EP67-Based Targeted Mucosal Vaccines to Prevent Primary Infection with CMV

  Vetro, J. A.

  National Institutes of Health

  2/1/16 → 1/31/21

  Project: Research project

  • Cytomegalovirus 100%
  • Mucosal Immunity 83%
  • Vaccines 66%
  • Intranasal Administration 56%
  • Infections 53%

• Novel Mechanisms of Cervical Cancer Development and Progression

  Wang, C.

  National Institutes of Health

  1/21/16 → 12/31/20

  Project: Research project

  • Uterine Cervical Neoplasms 100%
  • Carcinogenesis 19%
  • Oncogene Proteins 19%
  • Nude Mice 16%
  • Neoplasms 14%

• Cardiac Sympathetic Afferent Denervation and Remodeling in Heart Failure

  Zucker, I. H., Wang, H. & Wang, H.

  National Institutes of Health

  12/18/15 → 11/30/19

  Project: Research project

  • Reflex 100%
  • Sympathectomy 79%
  • Heart Failure 75%
  • Myocardial Infarction 69%
  • Autonomic Agents 24%

• Humanized Mice as a Tool to Monitor HIV Brain Reservoirs and Effects of Substance Abuse

  Gorantla, S., Poluektova, L. Y., Gorantla, S. & Poluektova, L. Y.

  National Institutes of Health

  9/30/15 → 7/31/18

  Project: Research project

  • Substance-Related Disorders 100%
  • HIV 84%
  • Brain 59%
  • Astrocytes 48%
  • Neuroglia 46%

• The Role of Astrocytic signaling in Synaptic Plasticity

  Dunaevsky, A.

  National Institutes of Health

  9/25/15 → 7/31/17

  Project: Research project

  • Astrocytes 75%
  • Neuronal Plasticity 61%
  • Learning 60%
  • Calcium Signaling 32%
  • Neurodevelopmental Disorders 32%

• Sensorimotor Learning in Children with Cerebral Palsy

  Kurz, M. J.

  National Institutes of Health

  9/24/15 → 6/30/19

  Project: Research project

  • Cerebral Palsy 100%
  • Learning 60%
  • Child 42%
  • Motor Skills 33%
  • Magnetoencephalography 24%

• Eunice Kennedy Shriver Intellectual and Developmental Disabilities Research Center at Vanderbilt University

  Mirnics, K.

  National Institutes of Health

  9/17/15 → 5/31/20

  Project: Research project

  • neurophysiology 100%
  • Developmental Disabilities 50%
  • Intellectual Disability 37%
  • instrumentation 28%
  • phenotype 27%

• Preventing relapse of destructive behavior using behavioral momentum theory

  Fisher, W. W.

  National Institutes of Health

  8/18/15 → 4/30/20

  Project: Research project

  • relapse 100%
  • communication 44%
  • Communication 31%
  • functional analysis 24%
  • caregiver 16%

• Targeted Core Shell Nanogels for Triple Negative Breast Cancer

  Kabanov, A., Rihe, L. & Bronich, T. K.

  National Institutes of Health

  8/14/15 → 7/31/20

  Project: Research project

  • Nanogels 100%
  • Triple Negative Breast Neoplasms 72%
  • Neoplasms 20%
  • Pharmaceutical Preparations 15%
  • Nanotechnology 12%

• HIV Tat & Morphine induce mircroglial migration & activation via release of miR-9 & 138

  Buch, S. J. & Fox, H. S.

  National Institutes of Health

  8/1/15 → 5/31/20

  Project: Research project

  • Morphine 100%
  • MicroRNAs 82%
  • HIV 64%
  • Opioid-Related Disorders 53%
  • Extracellular Vesicles 51%

• Ramipril treatment of claudication: oxidative damage and muscle fibrosis

  Pipinos, I. I. & Casale, G. P.

  National Institutes of Health

  8/1/15 → 3/31/20

  Project: Research project

  • Ramipril 100%
  • Peripheral Arterial Disease 66%
  • Fibrosis 38%
  • Muscular Diseases 36%
  • Muscles 34%

• Exome screening and directed breeding of rhesus for human genetic disease models

  Norgren, R. B. & Johnson, R. P.

  National Institutes of Health

  8/1/15 → 7/31/17

  Project: Research project

  • genetic disorders 100%
  • disease models 97%
  • loss-of-function mutation 84%
  • Macaca mulatta 84%
  • genetic models 82%

• Maternal Immune Activation in a Genetic Mouse Model of ASD

  Dunaevsky, A.

  National Institutes of Health

  8/1/15 → 5/31/19

  Project: Research project

  • Autism Spectrum Disorder 100%
  • Genetic Models 76%
  • Mothers 55%
  • Rett Syndrome 20%
  • Maternal Exposure 19%

• Targeted Radiation Therapy for Pancreatic Cancer

  Batra, S. K. & Jain, M.

  National Institutes of Health

  7/17/15 → 6/30/20

  Project: Research project

  • Pancreatic Neoplasms 100%
  • Radiotherapy 50%
  • Tumor Microenvironment 49%
  • Radiopharmaceuticals 46%
  • Radioisotopes 39%

• Evaluating the PKC Enzyme System in Human Colon Cancer

  Black, J. D.

  National Institutes of Health

  7/16/15 → 6/30/17

  Project: Research project

  • Protein Kinase C 100%
  • Colorectal Neoplasms 75%
  • Colonic Neoplasms 68%
  • Isoenzymes 60%
  • Enzymes 44%

• Polymeric Nanomedicines of Hedgehog Inhibitor and miRNA for Treating Pancreatic Cancer

  Mahato, R. I. & Batra, S. K.

  National Institutes of Health

  7/15/15 → 3/31/19

  Project: Research project

  • HhAntag691 100%
  • Hedgehogs 68%
  • Nanomedicine 61%
  • Pancreatic Neoplasms 49%
  • MicroRNAs 36%

• IGF-II-Based Approach to Therapy for Pancreatic Cancer

  MacDonald, R. G.

  National Institutes of Health

  7/14/15 → 6/30/17

  Project: Research project

  • Insulin-Like Growth Factor II 100%
  • Pancreatic Neoplasms 64%
  • Ligands 27%
  • Neoplasms 16%
  • Somatomedins 13%

• PDGF-CC Mediated Reversal of Synaptodendritic Injury in HAND

  Buch, S. J.

  National Institutes of Health

  7/3/15 → 5/31/20

  Project: Research project

  • Neurocognitive Disorders 100%
  • Platelet-Derived Growth Factor 79%
  • HIV 55%
  • Wounds and Injuries 29%
  • platelet-derived growth factor C 24%

• Transmitted/Founder SHIV macaque model

  Byrareddy, S.

  National Institutes of Health

  7/1/15 → 6/30/17

  Project: Research project

  • Macaca 100%
  • Viruses 77%
  • Vaccines 39%
  • Rwanda 16%
  • Zambia 15%

• MIC-1 and its functional partners in prostate cancer racial disparity

  Batra, S. K.

  National Institutes of Health

  5/1/15 → 4/30/20

  Project: Research project

  • African Americans 100%
  • Prostatic Neoplasms 87%
  • Docetaxel 35%
  • Prostate Cancer, Hereditary, 7 16%
  • Anticarcinogenic Agents 15%

• Dual-function nanoparticles for oral treatment of inflammatory bowel disease

  Oupicky, D.

  National Institutes of Health

  4/15/15 → 1/31/17

  Project: Research project

  • Inflammatory Bowel Diseases 100%
  • Nanoparticles 65%
  • Inflammation 30%
  • Therapeutics 16%
  • Anti-Inflammatory Agents 15%

• Nanoparticles based on histone deacetylase inhibitors for combination treatments

  Oupicky, D.

  National Institutes of Health

  4/1/15 → 3/31/17

  Project: Research project

  • Histone Deacetylase Inhibitors 100%
  • Nanoparticles 58%
  • Histone Deacetylases 35%
  • Pharmaceutical Preparations 34%
  • Lung Neoplasms 32%

• Research and Development of Novel Drug Delivery Systems Symposium

  Mahato, R. I.

  National Institutes of Health

  4/1/15 → 3/31/16

  Project: Research project

  • Congresses 100%
  • Drug Delivery Systems 74%
  • Pharmaceutical Preparations 52%
  • Financial Support 33%
  • Posters 32%

• Optimization of Antischistosomal Chemotypes

  Vennerstrom, J. L.

  National Institutes of Health

  2/1/15 → 1/31/20

  Project: Research project

  • Hydantoins 100%
  • Schistosomiasis 98%
  • 1,2,4-trioxane 78%
  • Carboxylic Acids 53%
  • Pharmaceutical Preparations 51%