• 2338 Citations
  • 22 h-Index
1985 …2020

Research output per year

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Research Output

  • 2338 Citations
  • 22 h-Index
  • 31 Article
  • 5 Review article
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Article
2019

Selective inhibition of histone deacetylases 1/2/6 in combination with gemcitabine: A promising combination for pancreatic cancer therapy

Laschanzky, R. S., Humphrey, L. E., Ma, J., Smith, L. M., Enke, T. J., Shukla, S. K., Dasgupta, A., Singh, P. K., Howell, G. M., Brattain, M. G., Ly, Q. P., Black, A. R. & Black, J. D., Sep 2019, In : Cancers. 11, 9, 1327.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
2018

Crosstalk between PKCα and PI3K/AKT Signaling Is Tumor Suppressive in the Endometrium

Hsu, A. H., Lum, M. A., Shim, K. S., Frederick, P. J., Morrison, C. D., Chen, B., Lele, S. M., Sheinin, Y. M., Daikoku, T., Dey, S. K., Leone, G., Black, A. R. & Black, J. D., Jul 17 2018, In : Cell Reports. 24, 3, p. 655-669 15 p.

Research output: Contribution to journalArticle

5 Scopus citations

Zyxin promotes colon cancer tumorigenesis in a mitotic phosphorylation-dependent manner and through CDK8-mediated YAP activation

Zhou, J., Zeng, Y., Cui, L., Chen, X., Stauffer, S., Wang, Z., Yu, F., Lele, S. M., Talmon, G. A., Black, A. R., Chen, Y. & Dong, J., Jul 17 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 29, p. E6760-E6769

Research output: Contribution to journalArticle

8 Scopus citations
2017

The miR-487b-3p/GRM3/TGFβ signaling axis is an important regulator of colon cancer tumorigenesis

Yi, H., Geng, L., Black, A., Talmon, G., Berim, L. & Wang, J., Jun 15 2017, In : Oncogene. 36, 24, p. 3477-3489 13 p.

Research output: Contribution to journalArticle

12 Scopus citations
2016

Protein Kinase Cα (PKCα) is resistant to long term desensitization/down-regulation by prolonged diacylglycerol stimulation

Lum, M. A., Barger, C. J., Hsu, A. H., Leontieva, O. V., Black, A. R. & Black, J. D., Mar 18 2016, In : Journal of Biological Chemistry. 291, 12, p. 6331-6346 16 p.

Research output: Contribution to journalArticle

3 Scopus citations
2014

Differential regulation of cyclin D1 expression by protein kinase Cα and ∈ signaling in intestinal epithelial cells

Pysz, M. A., Hao, F., Hizli, A. A., Lum, M. A., Swetzig, W. M., Black, A. R. & Black, J. D., Aug 8 2014, In : Journal of Biological Chemistry. 289, 32, p. 22268-22283 16 p.

Research output: Contribution to journalArticle

13 Scopus citations
2013

Agonist-induced down-regulation of endogenous protein kinase C α through an endolysosomal mechanism

Lum, M. A., Pundt, K. E., Paluch, B. E., Black, A. R. & Black, J. D., May 3 2013, In : Journal of Biological Chemistry. 288, 18, p. 13093-13109 17 p.

Research output: Contribution to journalArticle

11 Scopus citations

Heat shock proteins regulate activation-induced proteasomal degradation of the mature phosphorylated form of protein kinase C

Lum, M. A., Balaburski, G. M., Murphy, M. E., Black, A. R. & Black, J. D., Sep 20 2013, In : Journal of Biological Chemistry. 288, 38, p. 27112-27127 16 p.

Research output: Contribution to journalArticle

11 Scopus citations
2011

Protein kinase Cα signaling regulates inhibitor of DNA binding 1 in the intestinal epithelium

Hao, F., Pysz, M. A., Curry, K. J., Haas, K. N., Seedhouse, S. J., Black, A. R. & Black, J. D., May 20 2011, In : Journal of Biological Chemistry. 286, 20, p. 18104-18117 14 p.

Research output: Contribution to journalArticle

14 Scopus citations
2009

PKCα tumor suppression in the intestine is associated with transcriptional and translational inhibition of cyclin D1

Pysz, M. A., Leontieva, O. V., Bateman, N. W., Uronis, J. M., Curry, K. J., Threadgill, D. W., Janssen, K. P., Robine, S., Velcich, A., Augenlicht, L. H., Black, A. R. & Black, J. D., May 1 2009, In : Experimental Cell Research. 315, 8, p. 1415-1428 14 p.

Research output: Contribution to journalArticle

27 Scopus citations
2007
65 Scopus citations
2006

Characterization of the 12C4 survivin monoclonal antibody and insight into the expression of survivin in human adult tissues

Spaulding, B., Pan, D., Ghadersohi, A., Nielsen, G., Jensen, S., Gellert, F., Ling, X., Zhang, M., Black, A. & Li, F., Dec 2006, In : Histopathology. 49, 6, p. 622-633 12 p.

Research output: Contribution to journalArticle

27 Scopus citations

Protein kinase C α signaling inhibits cyclin D1 translation in intestinal epithelial cells

Hizli, A. A., Black, A. R., Pysz, M. A. & Black, J. D., May 26 2006, In : Journal of Biological Chemistry. 281, 21, p. 14596-14603 8 p.

Research output: Contribution to journalArticle

29 Scopus citations
2004

Cell cycle- and protein kinase C-specific effects of resiniferatoxin and resiniferonol 9,13,14-ortho-phenylacetate in intestinal epithelial cells

Frey, M. R., Clark, J. A., Bateman, N. W., Kazanietz, M. G., Black, A. R. & Black, J. D., May 15 2004, In : Biochemical Pharmacology. 67, 10, p. 1873-1886 14 p.

Research output: Contribution to journalArticle

6 Scopus citations

Intestinal Tumor Progression Is Associated with Altered Function of KLF5

Bateman, N. W., Tan, D., Pestell, R. G., Black, J. D. & Black, A. R., Mar 26 2004, In : Journal of Biological Chemistry. 279, 13, p. 12093-12101 9 p.

Research output: Contribution to journalArticle

104 Scopus citations

Involvement of the ERK Signaling Cascade in Protein Kinase C-mediated Cell Cycle Arrest in Intestinal Epithelial Cells

Clark, J. A., Black, A. R., Leontieva, O. V., Frey, M. R., Pysz, M. A., Kunneva, L., Woloszynska-Read, A., Roy, D. & Black, J. D., Mar 5 2004, In : Journal of Biological Chemistry. 279, 10, p. 9233-9247 15 p.

Research output: Contribution to journalArticle

58 Scopus citations
2002

SUMO-1 modification of human cytomegalovirus IE1/IE72

Spengler, M. L., Kurapatwinski, K., Black, A. R. & Azizkhan-Clifford, J., 2002, In : Journal of virology. 76, 6, p. 2990-2996 7 p.

Research output: Contribution to journalArticle

45 Scopus citations
2001

Polyamine depletion in human melanoma cells leads to G1 arrest associated with induction of p21WAF1/CIP1/SDI1, changes in the expression of p21-regulated genes, and a senescence-like phenotype

Kramer, D. L., Chen, Y., Diegelman, P., Alm, K., Black, A. R., Porter, C. W., Chang, B. D. & Roninson, I. B., Nov 1 2001, In : Cancer Research. 61, 21, p. 7754-7762 9 p.

Research output: Contribution to journalArticle

81 Scopus citations
2000

Protein kinase C signaling mediates a program of cell cycle withdrawal in the intestinal epithelium

Frey, M. R., Clark, J. A., Leontieva, O., Uronis, J. M., Black, A. R. & Black, J. D., Nov 13 2000, In : Journal of Cell Biology. 151, 4, p. 763-777 15 p.

Research output: Contribution to journalArticle

85 Scopus citations
1999

Growth/cell cycle regulation of Sp1 phosphorylation

Black, A. R., Jensen, D., Lin, S. Y. & Azizkhan, J. C., Jan 15 1999, In : Journal of Biological Chemistry. 274, 3, p. 1207-1215 9 p.

Research output: Contribution to journalArticle

148 Scopus citations
1997

Distinct roles for Sp1 and E2F sites in the growth/cell cycle regulation of the DHFR promoter

Jensen, D. E., Black, A. R., Swick, A. G. & Azizkhan, J. C., Oct 1 1997, In : Journal of Cellular Biochemistry. 67, 1, p. 24-31 8 p.

Research output: Contribution to journalArticle

55 Scopus citations

Identification of a viral kinase that phosphorylates specific E2Fs and pocket proteins

Pajovic, S., Wong, E. L., Black, A. R. & Azizkhan, J. C., Nov 1997, In : Molecular and cellular biology. 17, 11, p. 6459-6464 6 p.

Research output: Contribution to journalArticle

Open Access
58 Scopus citations
1996

Alternate splicing of the rTS gene product and its overexpression in a 5-fluorouracil-resistant cell line

Dolnick, B. J. & Black, A. R., Jul 15 1996, In : Cancer Research. 56, 14, p. 3207-3210 4 p.

Research output: Contribution to journalArticle

22 Scopus citations

Cell cycle-regulated association of E2F1 and Sp1 is related to their functional interaction

Lin, S. Y., Black, A. R., Kostic, D., Pajovic, S., Hoover, C. N. & Azizkhan, J. C., Apr 1996, In : Molecular and cellular biology. 16, 4, p. 1668-1675 8 p.

Research output: Contribution to journalArticle

Open Access
234 Scopus citations

Expression of rTS correlates with altered growth regulation of thymidylate synthase

Black, A. R. & Dolnick, B. J., Feb 15 1996, In : Cancer Research. 56, 4, p. 700-705 6 p.

Research output: Contribution to journalArticle

24 Scopus citations

rTS gene expression is associated with altered cell sensitivity to thymidylate synthase inhibitors

Dolnick, B. J., Black, A. R., Winkler, P. M., Schindler, K. & Hsueh, C. T., 1996, In : Advances in Enzyme Regulation. 36, p. 165-180 16 p.

Research output: Contribution to journalArticle

18 Scopus citations
1989

Involvement of rRNA synthesis in the enhanced survival and recovery of protein synthesis seen in thermotolerance

Black, A. R. & Subjeck, J. R., Mar 1989, In : Journal of Cellular Physiology. 138, 3, p. 439-449 11 p.

Research output: Contribution to journalArticle

20 Scopus citations
1988

Solubilization and Physical Characterization of Acceptors for Dendrotoxin and β-bungarotoxin from Synaptic Membranes of Rat Brain

Black, A. R., Donegan, C. M., Denny, B. J. & Dolly, J. O., Sep 1 1988, In : Biochemistry. 27, 18, p. 6814-6820 7 p.

Research output: Contribution to journalArticle

46 Scopus citations
1986

Involvement of neuronal acceptors for dendrotoxin in its convulsive action in rat brain

Black, A. R., Breeze, A. L., Othman, I. B. & Dolly, J. O., 1986, In : Biochemical Journal. 237, 2, p. 397-404 8 p.

Research output: Contribution to journalArticle

66 Scopus citations

Two acceptor sub‐types for dendrotoxin in chick synaptic membranes distinguishable by β‐bungarotoxin

BLACK, A. R. & DOLLY, J. O., May 1986, In : European Journal of Biochemistry. 156, 3, p. 609-617 9 p.

Research output: Contribution to journalArticle

47 Scopus citations
1985

A functional membranous acceptor for dendrotoxin in rat brain: Solubilization of the binding component

Mehraban, F., Black, A. R. & Breeze, A. L., 1985, In : Biochemical Society Transactions. 13, 2, p. 407-508 102 p.

Research output: Contribution to journalArticle

10 Scopus citations