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Dive into the research topics where Amarnath Natarajan is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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pBACH1 binding site on BRCT(BRCA1): A novel approach to cancer therapeutics
Project: Research project
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HTS to Identify Small Molecule Inhibitors of Phospho-Specific Protein-Protein Int
Project: Research project
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Phosphorylated Form of Activated IKKbeta and Pancreatic Cancer
Project: Research project
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Dimers of isatin derived α-methylene-γ-butyrolactone as potent anti-cancer agents
Rana, S., Kour, S., Kizhake, S., King, H. M., Mallareddy, J. R., Case, A. J., Huxford, T. & Natarajan, A., Jun 1 2022, In: Bioorganic and Medicinal Chemistry Letters. 65, 128713.Research output: Contribution to journal › Article › peer-review
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Fbxo7 promotes Cdk6 activity to inhibit PFKP and glycolysis in T cells
Harris, R., Yang, M., Schmidt, C., Royet, C., Singh, S., Natarajan, A., Morris, M., Frezza, C. & Laman, H., Jul 4 2022, In: Journal of Cell Biology. 221, 7, e202203095.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Genetic impairment of succinate metabolism disrupts bioenergetic sensing in adrenal neuroendocrine cancer
Gupta, P., Strange, K., Telange, R., Guo, A., Hatch, H., Sobh, A., Elie, J., Carter, A. M., Totenhagen, J., Tan, C., Sonawane, Y. A., Neuzil, J., Natarajan, A., Ovens, A. J., Oakhill, J. S., Wiederhold, T., Pacak, K., Ghayee, H. K., Meijer, L., Reddy, S., & 1 others, 2022, (Accepted/In press) In: Cell Reports. 111218.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Selective CDK9 degradation using a proteolysis-targeting chimera (PROTAC) strategy
Mallareddy, J. R., Singh, S., Boghean, L. & Natarajan, A., Jan 2022, In: Future Medicinal Chemistry. 14, 3, p. 131-134 4 p.Research output: Contribution to journal › Review article › peer-review
3 Scopus citations -
Small-molecule IKKβ activation modulator (IKAM) targets MAP3K1 and inhibits pancreatic tumor growth
Napoleon, J. V., Sagar, S., Kubica, S. P., Boghean, L., Kour, S., King, H. M., Sonawane, Y. A., Crawford, A. J., Gautam, N., Kizhake, S., Bialk, P. A., Kmiec, E., Mallareddy, J. R., Patil, P. P., Rana, S., Singh, S., Prahlad, J., Grandgenett, P. M., Borgstahl, G. E. O., Ghosal, G., & 4 others, May 3 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 18, e2115071119.Research output: Contribution to journal › Article › peer-review
Open Access