Projects per year
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Dive into the research topics where Amarnath Natarajan is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Projects
- 4 Finished
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Development of Quinoxaline Based IKKbeta Inhibitors for Kras Driven Cancers
5/9/16 → 4/30/21
Project: Research project
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Phosphorylated Form of Activated IKKbeta and Pancreatic Cancer
1/1/14 → 12/31/16
Project: Research project
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pBACH1 binding site on BRCT(BRCA1): A novel approach to cancer therapeutics
9/8/08 → 7/31/14
Project: Research project
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HTS to Identify Small Molecule Inhibitors of Phospho-Specific Protein-Protein Int
6/1/07 → 5/31/09
Project: Research project
Research output
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Aminopyrazole based CDK9 PROTAC sensitizes pancreatic cancer cells to venetoclax
King, H. M., Rana, S., Kubica, S. P., Mallareddy, J. R., Kizhake, S., Ezell, E. L., Zahid, M., Naldrett, M. J., Alvarez, S., Law, H. C. H., Woods, N. T. & Natarajan, A., Jul 1 2021, In: Bioorganic and Medicinal Chemistry Letters. 43, 128061.Research output: Contribution to journal › Article › peer-review
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Selective killing of homologous recombination-deficient cancer cell lines by inhibitors of the RPA:RAD52 protein-protein interaction
Al-Mugotir, M., Lovelace, J. J., George, J., Bessho, M., Pal, D., Struble, L., Kolar, C., Rana, S., Natarajan, A., Bessho, T. & Borgstahl, G. E. O., Mar 2021, In: PloS one. 16, 3 March, e0248941.Research output: Contribution to journal › Article › peer-review
Open Access -
Small molecule binding to inhibitor of nuclear factor kappa-B kinase subunit beta in an ATP non-competitive manner
Napoleon, J. V., Singh, S., Rana, S., Bendjennat, M., Kumar, V., Kizhake, S., Palermo, N. Y., Ouellette, M. M., Huxford, T. & Natarajan, A., May 11 2021, In: Chemical Communications. 57, 38, p. 4678-4681 4 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Small molecule induced polymerization of BCL6 facilitates SIAH1 mediated degradation
Rana, S. & Natarajan, A., Dec 2021, In: Signal Transduction and Targeted Therapy. 6, 1, 142.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
Structure activity relationship (SAR) study identifies a quinoxaline urea analog that modulates IKKβ phosphorylation for pancreatic cancer therapy
Sagar, S., Singh, S., Mallareddy, J. R., Sonawane, Y. A., Napoleon, J. V., Rana, S., Contreras, J. I., Rajesh, C., Ezell, E. L., Kizhake, S., Garrison, J. C., Radhakrishnan, P. & Natarajan, A., Oct 15 2021, In: European Journal of Medicinal Chemistry. 222, 113579.Research output: Contribution to journal › Article › peer-review