Asit K Pattnaik, PhD

  • 3499 Citations
  • 34 h-Index
1983 …2020

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2018

Discovery of a non-nucleoside RNA polymerase inhibitor for blocking Zika virus replication through in silico screening

Pattnaik, A., Palermo, N., Sahoo, B. R., Yuan, Z., Hu, D., Annamalai, A. S., Vu, H. L., Correas, I., Prathipati, P. K., Destache, C. J., Li, Q., Osorio, F. A., Pattnaik, A. K. & Xiang, S-H., Mar 2018, In : Antiviral Research. 151, p. 78-86 9 p.

Research output: Contribution to journalArticle

15 Scopus citations
2017

Cross reactivity of immune responses to porcine reproductive and respiratory syndrome virus infection

Correas, I., Osorio, F. A., Steffen, D., Pattnaik, A. K. & Vu, H. L. X., Feb 1 2017, In : Vaccine. 35, 5, p. 782-788 7 p.

Research output: Contribution to journalArticle

20 Scopus citations

Relative contribution of porcine reproductive and respiratory syndrome virus open reading frames 2–4 to the induction of protective immunity

Kimpston-Burkgren, K., Correas, I., Osorio, F. A., Steffen, D., Pattnaik, A. K., Fang, Y. & Vu, H. L. X., Aug 3 2017, In : Vaccine. 35, 34, p. 4408-4413 6 p.

Research output: Contribution to journalArticle

3 Scopus citations
17 Scopus citations

Zika virus encoding nonglycosylated envelope protein is attenuated and defective in neuroinvasion

Annamalai, A. S., Pattnaik, A., Sahoo, B. R., Muthukrishnan, E., Natarajan, S. K., Steffen, D., Vu, H. L. X., Delhon, G., Osorio, F. A., Petro, T. M., Xiang, S. H. & Pattnaik, A. K., Dec 1 2017, In : Journal of virology. 91, 23, e01348-17.

Research output: Contribution to journalArticle

38 Scopus citations
2016
6 Scopus citations
2015

A synthetic porcine reproductive and respiratory syndrome virus strain confers unprecedented levels of heterologous protection

Vu, H. L. X., Ma, F., Laegreid, W. W., Pattnaik, A. K., Steffen, D., Doster, A. R. & Osorio, F. A., 2015, In : Journal of virology. 89, 23, p. 12070-12083 14 p.

Research output: Contribution to journalArticle

19 Scopus citations

Mutations in the 5' NTR and the non-structural protein 3A of the coxsackievirus B3 selectively attenuate myocarditogenicity

Massilamany, C., Gangaplara, A., Basavalingappa, R. H., Rajasekaran, R. A., Vu, H., Riethoven, J. J., Steffen, D., Pattnaik, A. K. & Reddy, J., Jun 22 2015, In : PloS one. 10, 6, e0131052.

Research output: Contribution to journalArticle

5 Scopus citations

Trim21 regulates Nmi-IFI35 complex-mediated inhibition of innate antiviral response

Das, A., Dinh, P. X. & Pattnaik, A. K., Nov 1 2015, In : Virology. 485, p. 383-392 10 p.

Research output: Contribution to journalArticle

12 Scopus citations
2014

Interferon-inducible protein IFI35 negatively regulates RIG-I antiviral signaling and supports vesicular stomatitis virus replication

Das, A., Dinh, P. X., Panda, D. & Pattnaik, A. K., Mar 2014, In : Journal of virology. 88, 6, p. 3103-3113 11 p.

Research output: Contribution to journalArticle

42 Scopus citations

Protective humoral immune response induced by an inactivated porcine reproductive and respiratory syndrome virus expressing the hypo-glycosylated glycoprotein 5

Lee, J. A., Kwon, B., Osorio, F. A., Pattnaik, A. K., Lee, N. H., Lee, S. W., Park, S. Y., Song, C. S., Choi, I. S. & Lee, J. B., Jun 17 2014, In : Vaccine. 32, 29, p. 3617-3622 6 p.

Research output: Contribution to journalArticle

16 Scopus citations
2013

Characterization of a serologic marker candidate for development of a live-attenuated DIVA vaccine against porcine reproductive and respiratory syndrome virus

Vu, H. L. X., Kwon, B., de Lima, M., Pattnaik, A. K. & Osorio, F. A., Sep 13 2013, In : Vaccine. 31, 40, p. 4330-4337 8 p.

Research output: Contribution to journalArticle

6 Scopus citations
16 Scopus citations

Induction of stress granule-like structures in vesicular stomatitis virus-infected cells

Dinh, P. X., Beura, L. K., Das, P. B., Panda, D., Das, A. & Pattnaik, A. K., Jan 2013, In : Journal of virology. 87, 1, p. 372-383 12 p.

Research output: Contribution to journalArticle

30 Scopus citations

Manipulation of cellular processing bodies and their constituents by viruses

Pattnaik, A. K. & Dinh, P. X., Jun 1 2013, In : DNA and Cell Biology. 32, 6, p. 286-291 6 p.

Research output: Contribution to journalArticle

4 Scopus citations

Trex1 regulates lysosomal biogenesis and interferon-independent activation of antiviral genes

Hasan, M., Koch, J., Rakheja, D., Pattnaik, A. K., Brugarolas, J., Dozmorov, I., Levine, B., Wakeland, E. K., Lee-Kirsch, M. A. & Yan, N., Jan 2013, In : Nature Immunology. 14, 1, p. 61-71 11 p.

Research output: Contribution to journalArticle

98 Scopus citations
2012

Amino acid residues in the non-structural protein 1 of porcine reproductive and respiratory syndrome virus involved in down-regulation of TNF-α expression in vitro and attenuation in vivo

Subramaniam, S., Beura, L. K., Kwon, B., Pattnaik, A. K. & Osorio, F. A., Oct 25 2012, In : Virology. 432, 2, p. 241-249 9 p.

Research output: Contribution to journalArticle

19 Scopus citations

A single amino acid change resulting in loss of fluorescence of eGFP in a viral fusion protein confers fitness and growth advantage to the recombinant vesicular stomatitis virus

Dinh, P. X., Panda, D., Das, P. B., Das, S. C., Das, A. & Pattnaik, A. K., Oct 25 2012, In : Virology. 432, 2, p. 460-469 10 p.

Research output: Contribution to journalArticle

6 Scopus citations

Coxsackievirus B3 infection leads to the generation of cardiac myosin heavy chain-α-reactive CD4 T cells in A/J mice

Gangaplara, A., Massilamany, C., Brown, D. M., Delhon, G., Pattnaik, A. K., Chapman, N., Rose, N., Steffen, D. & Reddy, J., Sep 2012, In : Clinical Immunology. 144, 3, p. 237-249 13 p.

Research output: Contribution to journalArticle

40 Scopus citations
17 Scopus citations

Identification of amino acid residues important for anti-IFN activity of porcine reproductive and respiratory syndrome virus non-structural protein 1

Beura, L. K., Subramaniam, S., Vu, H. L. X., Kwon, B., Pattnaik, A. K. & Osorio, F. A., Nov 25 2012, In : Virology. 433, 2, p. 431-439 9 p.

Research output: Contribution to journalArticle

20 Scopus citations

Location of T-cell epitopes in nonstructural proteins 9 and 10 of type-II porcine reproductive and respiratory syndrome virus

Parida, R., Choi, I. S., Peterson, D. A., Pattnaik, A. K., Laegreid, W., Zuckermann, F. A. & Osorio, F. A., Oct 2012, In : Virus Research. 169, 1, p. 13-21 9 p.

Research output: Contribution to journalArticle

34 Scopus citations

Posttranslational modification of vesicular stomatitis virus glycoprotein, but not JNK inhibition, is the antiviral mechanism of SP600125

Marozin, S., Altomonte, J., Apfel, S., Dinh, P. X., De Toni, E. N., Rizzani, A., Nüssler, A., Kato, N., Schmid, R. M., Pattnaik, A. K. & Ebert, O., May 2012, In : Journal of virology. 86, 9, p. 4844-4855 12 p.

Research output: Contribution to journalArticle

5 Scopus citations
2011

Antagonistic effects of cellular poly(C) binding proteins on vesicular stomatitis virus gene expression

Dinh, P. X., Beura, L. K., Panda, D., Das, A. & Pattnaik, A. K., Sep 2011, In : Journal of virology. 85, 18, p. 9459-9471 13 p.

Research output: Contribution to journalArticle

28 Scopus citations

A virulent strain of porcine reproductive and respiratory syndrome virus does not up-regulate interleukin-10 levels in vitro or in vivo

Subramaniam, S., Sur, J. H., Kwon, B., Pattnaik, A. K. & Osorio, F. A., Feb 2011, In : Virus Research. 155, 2, p. 415-422 8 p.

Research output: Contribution to journalArticle

22 Scopus citations

Cellular poly(C) binding proteins 1 and 2 interact with porcine reproductive and respiratory syndrome virus nonstructural protein 1β and support viral replication

Beura, L. K., Dinh, P. X., Osorio, F. A. & Pattnaik, A. K., Dec 2011, In : Journal of virology. 85, 24, p. 12939-12949 11 p.

Research output: Contribution to journalArticle

34 Scopus citations

Glycosylation of minor envelope glycoproteins of porcine reproductive and respiratory syndrome virus in infectious virus recovery, receptor interaction, and immune response

Das, P. B., Vu, H. L. X., Dinh, P. X., Cooney, J. L., Kwon, B., Osorio, F. A. & Pattnaik, A. K., Feb 20 2011, In : Virology. 410, 2, p. 385-394 10 p.

Research output: Contribution to journalArticle

46 Scopus citations

Immune evasion of porcine reproductive and respiratory syndrome virus through glycan shielding involves both glycoprotein 5 as well as glycoprotein 3

Vu, H. L. X., Kwon, B., Yoon, K. J., Laegreid, W. W., Pattnaik, A. K. & Osorio, F. A., Jun 2011, In : Journal of virology. 85, 11, p. 5555-5564 10 p.

Research output: Contribution to journalArticle

73 Scopus citations

RNAi screening reveals requirement for host cell secretory pathway in infection by diverse families of negative-strand RNA viruses

Panda, D., Das, A., Dinh, P. X., Subramaniam, S., Nayak, D., Barrows, N. J., Pearson, J. L., Thompson, J., Kelly, D. L., Ladunga, I. & Pattnaik, A. K., Nov 22 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 47, p. 19036-19041 6 p.

Research output: Contribution to journalArticle

66 Scopus citations
2010
12 Scopus citations

Porcine reproductive and respiratory syndrome virus non-structural protein 1 suppresses tumor necrosis factor-alpha promoter activation by inhibiting NF-κB and Sp1

Subramaniam, S., Kwon, B., Beura, L. K., Kuszynski, C. A., Pattnaik, A. K. & Osorio, F. A., Oct 2010, In : Virology. 406, 2, p. 270-279 10 p.

Research output: Contribution to journalArticle

51 Scopus citations

Porcine reproductive and respiratory syndrome virus nonstructural protein 1β modulates host innate immune response by antagonizing IRF3 activation

Beura, L. K., Sarkar, S. N., Kwon, B., Subramaniam, S., Jones, C., Pattnaik, A. K. & Osorio, F. A., Feb 2010, In : Journal of virology. 84, 3, p. 1574-1584 11 p.

Research output: Contribution to journalArticle

180 Scopus citations

The minor envelope glycoproteins GP2a and GP4 of porcine reproductive and respiratory syndrome virus interact with the receptor CD163

Das, P. B., Dinh, P. X., Ansari, I. H., De Lima, M., Osorio, F. A. & Pattnaik, A. K., Feb 2010, In : Journal of virology. 84, 4, p. 1731-1740 10 p.

Research output: Contribution to journalArticle

122 Scopus citations
2009
1 Scopus citations
44 Scopus citations

GP3 is a structural component of the PRRSV type II (US) virion

de Lima, M., Ansari, I. H., Das, P. B., Ku, B. J., Martinez-Lobo, F. J., Pattnaik, A. K. & Osorio, F. A., Jul 20 2009, In : Virology. 390, 1, p. 31-36 6 p.

Research output: Contribution to journalArticle

33 Scopus citations

Single-amino-acid alterations in a highly conserved central region of vesicular stomatitis virus N protein differentially affect the viral nucleocapsid template functions

Nayak, D., Panda, D., Das, S. C., Luo, M. & Pattnaik, A. K., Jun 2009, In : Journal of virology. 83, 11, p. 5525-5534 10 p.

Research output: Contribution to journalArticle

23 Scopus citations
2008

A model for the dynamic nuclear/nucleolar/cytoplasmic trafficking of the porcine reproductive and respiratory syndrome virus (PRRSV) nucleocapsid protein based on live cell imaging

You, J. H., Howell, G., Pattnaik, A. K., Osorio, F. A. & Hiscox, J. A., Aug 15 2008, In : Virology. 378, 1, p. 34-47 14 p.

Research output: Contribution to journalArticle

17 Scopus citations

Development of a porcine reproductive and respiratory syndrome virus differentiable (DIVA) strain through deletion of specific immunodominant epitopes

de Lima, M., Kwon, B., Ansari, I. H., Pattnaik, A. K., Flores, E. F. & Osorio, F. A., Jul 4 2008, In : Vaccine. 26, 29-30, p. 3594-3600 7 p.

Research output: Contribution to journalArticle

28 Scopus citations

Identification of virulence determinants of porcine reproductive and respiratory syndrome virus through construction of chimeric clones

Kwon, B., Ansari, I. H., Pattnaik, A. K. & Osorio, F. A., Oct 25 2008, In : Virology. 380, 2, p. 371-378 8 p.

Research output: Contribution to journalArticle

52 Scopus citations

The ESCRT-I Subunit TSG101 controls endosome-to-cytosol release of viral RNA

Luyet, P. P., Falguières, T., Pons, V., Pattnaik, A. K. & Gruenberg, J., 2008, In : Traffic. 9, 12, p. 2279-2290 12 p.

Research output: Contribution to journalArticle

47 Scopus citations
2007

Hypersusceptibility to Vesicular Stomatitis Virus Infection in Dicer1-Deficient Mice Is Due to Impaired miR24 and miR93 Expression

Otsuka, M., Jing, Q., Georgel, P., New, L., Chen, J., Mols, J., Kang, YJ., Jiang, Z., Du, X., Cook, R., Das, S. C., Pattnaik, A. K., Beutler, B. & Han, J., Jul 27 2007, In : Immunity. 27, 1, p. 123-134 12 p.

Research output: Contribution to journalArticle

265 Scopus citations
2006
23 Scopus citations
183 Scopus citations

Insertion and deletion analyses identify regions of non-structural protein 5A of Hepatitis C virus that are dispensable for viral genome replication

Liu, S., Ansari, I. H., Das, S. C. & Pattnaik, A. K., Feb 2006, In : Journal of General Virology. 87, 2, p. 323-327 5 p.

Research output: Contribution to journalArticle

33 Scopus citations

Serologic marker candidates identified among B-cell linear epitopes of Nsp2 and structural proteins of a North American strain of porcine reproductive and respiratory syndrome virus

de Lima, M., Pattnaik, A. K., Flores, E. F. & Osorio, F. A., Sep 30 2006, In : Virology. 353, 2, p. 410-421 12 p.

Research output: Contribution to journalArticle

99 Scopus citations

Visualization of intracellular transport of vesicular stomatitis virus nucleocapsids in living cells

Das, S. C., Nayak, D., Zhou, Y. & Pattnaik, A. K., Jul 2006, In : Journal of virology. 80, 13, p. 6368-6377 10 p.

Research output: Contribution to journalArticle

91 Scopus citations
2005
35 Scopus citations
2004

A highly pathogenic porcine reproductive and respiratory syndrome virus generated from an infectious cDNA clone retains the in vivo virulence and transmissibility properties of the parental virus

Truong, H. M., Lu, Z., Kutish, G. F., Galeota, J., Osorio, F. A. & Pattnaik, A. K., Aug 1 2004, In : Virology. 325, 2, p. 308-319 12 p.

Research output: Contribution to journalArticle

85 Scopus citations

Phosphorylation of vesicular stomatitis virus phosphoprotein P is indispensable for virus growth

Das, S. C. & Pattnaik, A. K., Jun 2004, In : Journal of virology. 78, 12, p. 6420-6430 11 p.

Research output: Contribution to journalArticle

40 Scopus citations