Audrey J Lazenby, MD

  • 11623 Citations
  • 50 h-Index
1987 …2020

Research output per year

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Research Output

2020

Metabolic alterations in pancreatic cancer progression

Vernucci, E., Abrego, J., Gunda, V., Shukla, S. K., Dasgupta, A., Rai, V., Chaika, N., Buettner, K., Illies, A., Yu, F., Lazenby, A. J., Swanson, B. J. & Singh, P. K., Jan 2020, In : Cancers. 12, 1, 2.

Research output: Contribution to journalArticle

Open Access

Prognostic and therapeutic implications of NHERF1 expression and regulation in colorectal cancer

Leiphrakpam, P. D., Lazenby, A. J., Chowdhury, S., Smith, L. M., Mathiesen, M., Brattain, M. G., Wang, J., Black, J. D. & Are, C., Mar 1 2020, In : Journal of Surgical Oncology. 121, 3, p. 547-560 14 p.

Research output: Contribution to journalArticle

2019

Genetic/Familial high-risk assessment: Colorectal, version 2.2019 featured updates to the NCCN guidelines

Gupta, S., Provenzale, D., Llor, X., Halverson, A. L., Grady, W., Chung, D. C., Haraldsdottir, S., Markowitz, A. J., Slavin, T. P., Hampel, H., Ness, R. M., Weiss, J. M., Ahnen, D. J., Chen, L. M., Cooper, G., Early, D. S., Giardiello, F. M., Hall, M. J., Hamilton, S. R., Kanth, P. & 9 others, Klapman, J. B., Lazenby, A. J., Lynch, P. M., Mayer, R. J., Mikkelson, J., Peter, S., Regenbogen, S. E., Dwyer, M. A. & Ogba, N., Jan 1 2019, In : JNCCN Journal of the National Comprehensive Cancer Network. 17, 9, p. 1032-1041 10 p.

Research output: Contribution to journalArticle

Open Access
13 Scopus citations
2 Scopus citations
2018
6 Scopus citations

NCCN Guidelines(r) insights colorectal cancer screening, version 1.2018 featured updates to the NCCN guidelines

Provenzale, D., Gupta, S., Ahnen, D. J., Markowitz, A. J., Chung, D. C., Mayer, R. J., Regenbogen, S. E., Blanco, A. M., Bray, T., Cooper, G., Early, D. S., Ford, J. M., Giardiello, F. M., Grady, W., Hall, M. J., Halverson, A. L., Hamilton, S. R., Hampel, H., Klapman, J. B., Larson, D. W. & 10 others, Lazenby, A. J., Llor, X., Lynch, P. M., Mikkelson, J., Ness, R. M., Slavin, T. P., Sugandha, S., Weiss, J. M., Dwyer, M. A. & Ogba, N., Aug 1 2018, In : JNCCN Journal of the National Comprehensive Cancer Network. 16, 8, p. 939-949 11 p.

Research output: Contribution to journalReview article

23 Scopus citations
2017

Chronic mesenteric ischemia and gastric ischemia: a bad combination

Ahmad, D. S., Sahak, K., Lazenby, A. J. & Bhat, I., Sep 2017, In : Gastrointestinal Endoscopy. 86, 3, p. 564-565 2 p.

Research output: Contribution to journalArticle

4 Scopus citations

De Novo lipid synthesis facilitates gemcitabine resistance through endoplasmic reticulum stress in pancreatic cancer

Tadros, S., Shukla, S. K., King, R. J., Gunda, V., Vernucci, E., Abrego, J., Chaika, N. V., Yu, F., Lazenby, A. J., Berim, L., Grem, J., Sasson, A. R. & Singh, P. K., Oct 15 2017, In : Cancer Research. 77, 20, p. 5503-5517 15 p.

Research output: Contribution to journalArticle

30 Scopus citations
15 Scopus citations

Enhancer Reprogramming Promotes Pancreatic Cancer Metastasis

Roe, J. S., Hwang, C. I., Somerville, T. D. D., Milazzo, J. P., Lee, E. J., Da Silva, B., Maiorino, L., Tiriac, H., Young, C. M., Miyabayashi, K., Filippini, D., Creighton, B., Burkhart, R. A., Buscaglia, J. M., Kim, E. J., Grem, J. L., Lazenby, A. J., Grunkemeyer, J. A., Hollingsworth, M. A., Grandgenett, P. M. & 4 others, Egeblad, M., Park, Y., Tuveson, D. A. & Vakoc, C. R., Aug 24 2017, In : Cell. 170, 5, p. 875-888.e20

Research output: Contribution to journalArticle

102 Scopus citations

Erratum: MUC1 and HIF-1alpha Signaling Crosstalk Induces Anabolic Glucose Metabolism to Impart Gemcitabine Resistance to Pancreatic Cancer (Cancer Cell (2017) 32(1) (71–87.e7) (S1535610817302544) (10.1016/j.ccell.2017.06.004))

Shukla, S. K., Purohit, V., Mehla, K., Gunda, V., Chaika, N. V., Vernucci, E., King, R. J., Abrego, J., Goode, G. D., Dasgupta, A., Illies, A. L., Gebregiworgis, T., Dai, B., Augustine, J. J., Murthy, D., Attri, K. S., Mashadova, O., Grandgenett, P. M., Powers, R., Ly, Q. P. & 17 others, Lazenby, A. J., Grem, J. L., Yu, F., Matés, J. M., Asara, J. M., Kim, J. W., Hankins, J. H., Weekes, C., Hollingsworth, M. A., Serkova, N. J., Sasson, A. R., Fleming, J. B., Oliveto, J. M., Lyssiotis, C. A., Cantley, L. C., Berim, L. & Singh, P., Sep 11 2017, In : Cancer Cell. 32, 3, 1 p.

Research output: Contribution to journalComment/debate

15 Scopus citations

MUC1 and HIF-1alpha Signaling Crosstalk Induces Anabolic Glucose Metabolism to Impart Gemcitabine Resistance to Pancreatic Cancer

Shukla, S. K., Purohit, V., Mehla, K., Gunda, V., Chaika, N. V., Vernucci, E., King, R. J., Abrego, J., Goode, G. D., Dasgupta, A., Illies, A. L., Gebregiworgis, T., Dai, B., Augustine, J. J., Murthy, D., Attri, K. S., Mashadova, O., Grandgenett, P. M., Powers, R., Ly, Q. P. & 17 others, Lazenby, A. J., Grem, J. L., Yu, F., Matés, J. M., Asara, J. M., Kim, J. W., Hankins, J. H., Weekes, C., Hollingsworth, M. A., Serkova, N. J., Sasson, A. R., Fleming, J. B., Oliveto, J. M., Lyssiotis, C. A., Cantley, L. C., Berim, L. & Singh, P. K., Jul 10 2017, In : Cancer Cell. 32, 1, p. 71-87.e7

Research output: Contribution to journalArticle

105 Scopus citations

Mucins and associated O-glycans based immunoprofile for stratification of colorectal polyps: Clinical implication for improved colon surveillance

Krishn, S. R., Kaur, S., Sheinin, Y. M., Smith, L. M., Gautam, S. K., Patel, A., Jain, M., Juvvigunta, V., Pai, P., Lazenby, A. J., Roy, H. K. & Batra, S. K., Jan 1 2017, In : Oncotarget. 8, 4, p. 7025-7038 14 p.

Research output: Contribution to journalArticle

9 Scopus citations

Myeloid-derived cullin 3 promotes STAT3 phosphorylation by inhibiting OGT expression and protects against intestinal inflammation

Li, X., Zhang, Z., Li, L., Gong, W., Lazenby, A. J., Swanson, B. J., Herring, L. E., Asara, J. M., Singer, J. D. & Wen, H., Apr 1 2017, In : Journal of Experimental Medicine. 214, 4, p. 1093-1109 17 p.

Research output: Contribution to journalArticle

19 Scopus citations

NCCN guidelines® insights: Genetic/Familial High-Risk Assessment: Colorectal, version 3.2017 featured updates to the NCCN Guidelines

Gupta, S., Provenzale, D., Regenbogen, S. E., Hampel, H., Slavin, T. P., Hall, M. J., Llor, X., Chung, D. C., Ahnen, D. J., Bray, T., Cooper, G., Early, D. S., Ford, J. M., Giardiello, F. M., Grady, W., Halverson, A. L., Hamilton, S. R., Klapman, J. B., Larson, D. W., Lazenby, A. J. & 10 others, Lynch, P. M., Markowitz, A. J., Mayer, R. J., Ness, R. M., Samadder, N. J., Shike, M., Sugandha, S., Weiss, J. M., Dwyer, M. A. & Ogba, N., Dec 1 2017, In : JNCCN Journal of the National Comprehensive Cancer Network. 15, 12, p. 1465-1475 11 p.

Research output: Contribution to journalReview article

54 Scopus citations

The apoptotic crypt abscess an underappreciated histologic finding in gastrointestinal pathology

Talmon, G., Manasek, T., Miller, R., Muirhead, D. & Lazenby, A., Dec 1 2017, In : American journal of clinical pathology. 148, 6, p. 538-544 7 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2016

Genetic/familial high-risk assessment: Colorectal version 1.2016: Clinical practice guidelines in oncology

Provenzale, D., Gupta, S., Ahnen, D. J., Bray, T., Cannon, J. A., Cooper, G., David, D. S., Early, D. S., Erwin, D., Ford, J. M., Giardiello, F. M., Grady, W., Halverson, A. L., Hamilton, S. R., Hampel, H., Ismail, M. K., Klapman, J. B., Larson, D. W., Lazenby, A. J., Lynch, P. M. & 9 others, Mayer, R. J., Ness, R. M., Regenbogen, S. E., Samadder, N. J., Shike, M., Steinbach, G., Weinberg, D., Dwyer, M. & Darlow, S., Aug 1 2016, In : JNCCN Journal of the National Comprehensive Cancer Network. 14, 8, p. 1010-1030 21 p.

Research output: Contribution to journalArticle

Open Access
87 Scopus citations

Massive adrenal vein aneurysm mimicking an adrenal tumor in a patient with hemophilia A: a case report and review of the literature

Sleightholm, R., Wahlmeier, S., Carson, J. S., Drincic, A., Lazenby, A. & Foster, J. M., Dec 1 2016, In : Journal of Medical Case Reports. 10, 1, p. 1-6 6 p.

Research output: Contribution to journalArticle

2 Scopus citations

Up-Regulation of N-Cadherin by Collagen I-activated discoidin domain receptor 1 in pancreatic cancer requires the adaptor molecule Shc

Huang, H., Svoboda, R. A., Lazenby, A. J., Saowapa, J., Chaika, N., Ding, K., Wheelock, M. J. & Johnson, K. R., Oct 28 2016, In : Journal of Biological Chemistry. 291, 44, p. 23208-23223 16 p.

Research output: Contribution to journalArticle

23 Scopus citations
2015

Colorectal cancer screening, version 1.2015: Featured updates to the NCCN guidelines

Provenzale, D., Jasperson, K., Ahnen, D. J., Aslanian, H., Bray, T., Cannon, J. A., David, D. S., Early, D. S., Erwin, D., Ford, J. M., Giardiello, F. M., Gupta, S., Halverson, A. L., Hamilton, S. R., Hampel, H., Ismail, M. K., Klapman, J. B., Larson, D. W., Lazenby, A. J., Lynch, P. M. & 10 others, Mayer, R. J., Ness, R. M., Rao, M. S., Regenbogen, S. E., Shike, M., Steinbach, G., Weinberg, D., Dwyer, M. A., Freedman-Cass, D. A. & Darlow, S., Aug 1 2015, In : JNCCN Journal of the National Comprehensive Cancer Network. 13, 8, p. 959-968 10 p.

Research output: Contribution to journalArticle

Open Access
58 Scopus citations

Incidence of Gastric Cancer in Marrakech and Casablanca, Morocco

Smith, B. L., Khouchani, M., Karkouri, M., Lazenby, A. J., Watkins, K., Tahri, A., Benider, A. L., Rajaram, S. & Soliman, A. S., Jan 1 2015, In : Journal of Cancer Epidemiology. 2015, 704569.

Research output: Contribution to journalArticle

MUC16-mediated activation of mTOR and c-MYC reprograms pancreatic cancer metabolism

Shukla, S. K., Gunda, V., Abrego, J., Haridas, D., Mishra, A., Souchek, J., Chaika, N. V., Yu, F., Sasson, A. R., Lazenby, A. J., Batra, S. K. & Singh, P. K., Jan 1 2015, In : Oncotarget. 6, 22, p. 19118-19131 14 p.

Research output: Contribution to journalArticle

Open Access
32 Scopus citations
2014

Ezrin expression and cell survival regulation in colorectal cancer

Leiphrakpam, P. D., Rajput, A., Mathiesen, M., Agarwal, E., Lazenby, A. J., Are, C., Brattain, M. G. & Chowdhury, S., May 1 2014, In : Cellular Signalling. 26, 5, p. 868-879 12 p.

Research output: Contribution to journalArticle

19 Scopus citations

Unbiased analysis of pancreatic cancer radiation resistance reveals cholesterol biosynthesis as a novel target for radiosensitisation.

Souchek, J. J., Baine, M. J., Lin, C., Rachagani, S., Gupta, S., Kaur, S., Lester, K., Zheng, D., Chen, S., Smith, L. M., Lazenby, A. J., Johansson, S. L., Jain, M. & Batra, S. K., Sep 9 2014, In : British journal of cancer. 111, 6, p. 1139-1149 11 p.

Research output: Contribution to journalArticle

33 Scopus citations
26 Scopus citations
2013

Aberrant expression of mucin core proteins and O-linked glycans associated with progression of pancreatic cancer

Remmers, N., Anderson, J. M., Linde, E. M., DiMaio, D. J., Lazenby, A. J., Wandall, H. H., Mandel, U., Clausen, H., Yu, F. & Hollingsworth, M. A., Apr 15 2013, In : Clinical Cancer Research. 19, 8, p. 1981-1993 13 p.

Research output: Contribution to journalArticle

99 Scopus citations

Collagenous colitis in children and adolescents: Study of 7 cases and literature review

Liu, X., Xiao, S. Y., Plesec, T. P., Jiang, W., Goldblum, J. R. & Lazenby, A. J., Jun 1 2013, In : Modern Pathology. 26, 6, p. 881-887 7 p.

Research output: Contribution to journalArticle

9 Scopus citations

Colorectal cancer screening: Clinical practice guidelines in oncology

Burt, R. W., Cannon, J. A., David, D. S., Early, D. S., Ford, J. M., Giardiello, F. M., Halverson, A. L., Hamilton, S. R., Hampel, H., Ismail, M. K., Jasperson, K., Klapman, J. B., Lazenby, A. J., Lynch, P. M., Mayer, R. J., Ness, R. M., Provenzale, D., Rao, M. S., Shike, M., Steinbach, G. & 4 others, Terdiman, J. P., Weinberg, D., Dwyer, M. & Freedman-Cass, D., Dec 1 2013, In : JNCCN Journal of the National Comprehensive Cancer Network. 11, 12, p. 1538-1575 38 p.

Research output: Contribution to journalReview article

Open Access
53 Scopus citations
2012

Concordance between whole-slide imaging and light microscopy for routine surgical pathology

Scott Campbell, W., Lele, S. M., West, W. W., Lazenby, A. J., Smith, L. M. & Hinrichs, S. H., Oct 1 2012, In : Human Pathology. 43, 10, p. 1739-1744 6 p.

Research output: Contribution to journalArticle

50 Scopus citations

Differential expression of metabolic genes in tumor and stromal components of primary and metastatic loci in pancreatic adenocarcinoma

Chaika, N. V., Yu, F., Purohit, V., Mehla, K., Lazenby, A. J., DiMaio, D., Anderson, J. M., Yeh, J. J., Johnson, K. R., Hollingsworth, M. A. & Singh, P. K., Mar 7 2012, In : PloS one. 7, 3, e32996.

Research output: Contribution to journalArticle

50 Scopus citations

Gastric adenocarcinoma with chief cell differentiation: A proposal for reclassification as oxyntic gland polyp/adenoma

Singhi, A. D., Lazenby, A. J. & Montgomery, E. A., Jul 1 2012, In : American Journal of Surgical Pathology. 36, 7, p. 1030-1035 6 p.

Research output: Contribution to journalArticle

44 Scopus citations

Translocation t(12;17)(q24.1;q21) as the sole anomaly in a nasal chondromesenchymal hamartoma arising in a patient with pleuropulmonary blastoma

El Behery, R., Bedrnicek, J., Lazenby, A., Nelson, M., Grove, J., Huang, D., Smith, R. & Bridge, J. A., Aug 27 2012, In : Pediatric and Developmental Pathology. 15, 3, p. 249-253 5 p.

Research output: Contribution to journalArticle

7 Scopus citations
2010

Colorectal cancer screening: Clinical practice guidelines in oncology™

Burt, R. W., Barthel, J. S., Dunn, K. B., David, D. S., Drelichman, E., Ford, J. M., Giardiello, F. M., Gruber, S. B., Halverson, A. L., Hamilton, S. R., Ismail, M. K., Jasperson, K., Lazenby, A. J., Lynch, P. M., Martin, E. W., Mayer, R. J., Ness, R. M., Provenzale, D., Rao, M. S., Shike, M. & 3 others, Steinbach, G., Terdiman, J. P. & Weinberg, D., Jan 2010, In : JNCCN Journal of the National Comprehensive Cancer Network. 8, 1, p. 8-60 53 p.

Research output: Contribution to journalReview article

121 Scopus citations

NCCN clinical practice guidelines in oncology. Colorectal cancer screening.

Burt, R. W., Barthel, J. S., Dunn, K. B., David, D. S., Drelichman, E., Ford, J. M., Giardiello, F. M., Gruber, S. B., Halverson, A. L., Hamilton, S. R., Ismail, M. K., Jasperson, K., Lazenby, A. J., Lynch, P. M., Martin, E. W., Mayer, R. J., Ness, R. M., Provenzale, D., Rao, M. S., Shike, M. & 3 others, Steinbach, G., Terdiman, J. P. & Weinberg, D., Jan 2010, In : Journal of the National Comprehensive Cancer Network : JNCCN. 8, 1, p. 8-61 54 p.

Research output: Contribution to journalArticle

Rapid onset metastatic pulmonary calcifications in end-stage renal disease

Tendulkar, K., Lazenby, A. J. & Groggel, G. C., Mar 1 2010, In : Dialysis and Transplantation. 39, 3, p. 109-111 3 p.

Research output: Contribution to journalArticle

1 Scopus citations
2009

Polyps of the Esophagus

Lazenby, A., Dec 1 2009, Surgical Pathology of the GI Tract, Liver, Biliary Tract and Pancreas. Elsevier Inc., p. 405-413 9 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations
2008

Multiple gastrointestinal stromal tumors and lipomatosis

Liu, X., Wilcox, C. M., Nodit, L. & Lazenby, A. J., Nov 1 2008, In : Archives of Pathology and Laboratory Medicine. 132, 11, p. 1825-1829 5 p.

Research output: Contribution to journalArticle

7 Scopus citations

Sinonasal teratocarcinosarcoma: report of a case with review of literature and treatment outcome

Wei, S., Carroll, W., Lazenby, A., Bell, W., Lopez, R. & Said-Al-Naief, N., Dec 1 2008, In : Annals of Diagnostic Pathology. 12, 6, p. 415-425 11 p.

Research output: Contribution to journalArticle

30 Scopus citations
2007

Graft-versus-host-like disease complicating thymoma: Lack of AIRE expression as a cause of non-hereditary autoimmunity?

Offerhaus, G. J., Schipper, M. E. I., Lazenby, A. J., Montgomery, E., Morsink, F. H. M., Bende, R. J., Musler, A. R., van Lier, R. A. W. & van Noesel, C. J. M., Nov 30 2007, In : Immunology Letters. 114, 1, p. 31-37 7 p.

Research output: Contribution to journalArticle

26 Scopus citations

Influence of liver biopsy heterogeneity and diagnosis of nonalcoholic steatohepatitis in subjects undergoing gastric bypass

Arun, J., Jhala, N., Lazenby, A. J., Clements, R. & Abrams, G. A., Feb 1 2007, In : Obesity Surgery. 17, 2, p. 155-161 7 p.

Research output: Contribution to journalArticle

38 Scopus citations

Resolution of nonalcoholic steatohepatits after gastric bypass surgery

Liu, X., Lazenby, A. J., Clements, R. H., Jhala, N. & Abrams, G. A., Apr 1 2007, In : Obesity Surgery. 17, 4, p. 486-492 7 p.

Research output: Contribution to journalArticle

104 Scopus citations

Surgical Management of a Giant Thoracic Angiomyolipoma

Holman, W. L., Diethelm, L., Lazenby, A. J., Winokur, T. S., Lyerly, R. T. & Cerfolio, R. J., Jun 1 2007, In : Annals of Thoracic Surgery. 83, 6, p. 2201-2203 3 p.

Research output: Contribution to journalArticle

2006

Cytomegalovirus blocks intestinal stroma-induced down-regulation of macrophage HIV-1 infection

Maheshwari, A., Smythies, L. E., Wu, X., Novak, L., Clements, R., Eckhoff, D., Lazenby, A. J., Britt, W. J. & Smith, P. D., Nov 1 2006, In : Journal of Leukocyte Biology. 80, 5, p. 1111-1117 7 p.

Research output: Contribution to journalArticle

16 Scopus citations

Diagnostic quality of polyps resected by snare polypectomy: Does the type of electrosurgical current used matter?

Fry, L. C., Lazenby, A. J., Mikolaenko, I., Barranco, B., Rickes, S. & Mönkemüller, K., Sep 1 2006, In : American Journal of Gastroenterology. 101, 9, p. 2123-2127 5 p.

Research output: Contribution to journalArticle

35 Scopus citations

Prospective endoscopic evaluation for gastrointestinal graft-versus-host disease: Determination of the best diagnostic approach

Thompson, B., Salzman, D., Steinhauer, J., Lazenby, A. J. & Wilcox, C. M., Sep 1 2006, In : Bone marrow transplantation. 38, 5, p. 371-376 6 p.

Research output: Contribution to journalArticle

71 Scopus citations

Signal transduction cross-talk during colorectal tumorigenesis

Liu, X., Lazenby, A. J. & Siegal, G. P., Sep 1 2006, In : Advances in anatomic pathology. 13, 5, p. 270-274 5 p.

Research output: Contribution to journalReview article

23 Scopus citations

The prevalence of nonalcoholic steatohepatitis is greater in morbidly obese men compared to women

Arun, J., Clements, R. H., Lazenby, A. J., Leeth, R. R. & Abrams, G. A., Oct 1 2006, In : Obesity Surgery. 16, 10, p. 1351-1358 8 p.

Research output: Contribution to journalArticle

39 Scopus citations
2005

Collagenous and lymphocytic colitis

Lazenby, A. J., Nov 1 2005, In : Seminars in Diagnostic Pathology. 22, 4, p. 295-300 6 p.

Research output: Contribution to journalArticle

51 Scopus citations

Diverticular colitis

Lazenby, A. J., Jan 1 2005, In : Advances in experimental medicine and biology. 563, p. 30-34 5 p.

Research output: Contribution to journalReview article