Carol B Toris, PhD

  • 3960 Citations
  • 35 h-Index
1984 …2019

Research output per year

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Research Output

2019

A Highly Effective and Ultra-Long-Acting Anti-Glaucoma Drug, with a Novel Periorbital Delivery Method

Woodward, D. F., Wang, J. W., Coleman, R. A., Woodrooffe, A. J., Clark, K. L., Stamer, W. D., Tao, G., Fan, S. & Toris, C. B., Jun 2019, In : Journal of Ocular Pharmacology and Therapeutics. 35, 5, p. 265-277 13 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Antiglaucoma EP2 Agonists: A long road that led somewhere

Woodward, D. F., Wang, J. W., Stamer, W. D., Lütjen-Drecoll, E., Krauss, A. H. P. & Toris, C. B., Nov 2019, In : Journal of Ocular Pharmacology and Therapeutics. 35, 9, p. 469-474 6 p.

Research output: Contribution to journalReview article

Changes in Parameters of Aqueous Humor Dynamics Throughout Life

Toris, C. B., Tye, G. & Pattabiraman, P., 2019, Modeling and Simulation in Science, Engineering and Technology. Birkhauser, p. 161-190 30 p. (Modeling and Simulation in Science, Engineering and Technology).

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Differences in ocular biometrics and aqueous humour dynamics between Chinese and Caucasian adults

Fan, S., Guo, T., Chen, B., Xiong, J., Havens, S., Gulati, V. & Toris, C. B., Dec 1 2019, In : British Journal of Ophthalmology. 103, 12, p. 1845-1849 5 p.

Research output: Contribution to journalArticle

1 Scopus citations

Effect of Timolol on Aqueous Humor Outflow Facility in Healthy Human Eyes

Kazemi, A., McLaren, J. W., Trese, M. G. J., Toris, C. B., Gulati, V., Fan, S., Reed, D. M., Kristoff, T., Gilbert, J., Moroi, S. E. & Sit, A. J., Jun 2019, In : American journal of ophthalmology. 202, p. 126-132 7 p.

Research output: Contribution to journalArticle

2 Scopus citations

Response: Effects of Sex Hormones on Ocular Blood Flow and Intraocular Pressure in Primary Open-Angle Glaucoma: the Effect of Orgasm and Sexual Activity

Patel, P., Harris, A., Toris, C., Tobe, L., Lang, M., Belamkar, A., Ng, A., Vercellin, A. C. V., Mathew, S. & Siesky, B., Apr 1 2019, In : Journal of Glaucoma. 28, 4, p. E66-E67

Research output: Contribution to journalLetter

The affinity, intrinsic activity and selectivity of a structurally novel EP 2 receptor agonist at human prostanoid receptors

Coleman, R. A., Woodrooffe, A. J., Clark, K. L., Toris, C. B., Fan, S., Wang, J. W. & Woodward, D. F., Mar 2019, In : British Journal of Pharmacology. 176, 5, p. 687-698 12 p.

Research output: Contribution to journalArticle

2 Scopus citations

The future of canine glaucoma therapy

Komáromy, A. M., Bras, D., Esson, D. W., Fellman, R. L., Grozdanic, S. D., Kagemann, L., Miller, P. E., Moroi, S. E., Plummer, C. E., Sapienza, J. S., Storey, E. S., Teixeira, L. B., Toris, C. B. & Webb, T. R., Sep 1 2019, In : Veterinary Ophthalmology. 22, 5, p. 726-740 15 p.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations
2018

Consensus recommendations for trabecular meshwork cell isolation, characterization and culture

Keller, K. E., Bhattacharya, S. K., Borrás, T., Brunner, T. M., Chansangpetch, S., Clark, A. F., Dismuke, W. M., Du, Y., Elliott, M. H., Ethier, C. R., Faralli, J. A., Freddo, T. F., Fuchshofer, R., Giovingo, M., Gong, H., Gonzalez, P., Huang, A., Johnstone, M. A., Kaufman, P. L., Kelley, M. J. & 37 others, Knepper, P. A., Kopczynski, C. C., Kuchtey, J. G., Kuchtey, R. W., Kuehn, M. H., Lieberman, R. L., Lin, S. C., Liton, P., Liu, Y., Lütjen-Drecoll, E., Mao, W., Masis-Solano, M., McDonnell, F., McDowell, C. M., Overby, D. R., Pattabiraman, P. P., Raghunathan, V. K., Rao, P. V., Rhee, D. J., Chowdhury, U. R., Russell, P., Samples, J. R., Schwartz, D., Stubbs, E. B., Tamm, E. R., Tan, J. C., Toris, C. B., Torrejon, K. Y., Vranka, J. A., Wirtz, M. K., Yorio, T., Zhang, J., Zode, G. S., Fautsch, M. P., Peters, D. M., Acott, T. S. & Stamer, W. D., Jun 2018, In : Experimental Eye Research. 171, p. 164-173 10 p.

Research output: Contribution to journalShort survey

48 Scopus citations

Consequences of puberty on efficacy of intraocular pressure-lowering drugs in male Dutch-belted rabbits

Hays, C. L., Okafor, K. C., Fan, S., High, R., Singh, D. P. & Toris, C. B., Jan 1 2018, In : Journal of Ocular Pharmacology and Therapeutics. 34, 1-2, p. 76-84 9 p.

Research output: Contribution to journalArticle

1 Scopus citations

Effects of a Novel Selective EP2 Receptor Agonist, Omidenepag Isopropyl, on Aqueous Humor Dynamics in Laser-Induced Ocular Hypertensive Monkeys

Fuwa, M., Toris, C. B., Fan, S., Taniguchi, T., Ichikawa, M., Odani-Kawabata, N., Iwamura, R., Yoneda, K., Matsugi, T., Shams, N. K. & Zhang, J. Z., Sep 2018, In : Journal of Ocular Pharmacology and Therapeutics. 34, 7, p. 531-537 7 p.

Research output: Contribution to journalArticle

10 Scopus citations

Effects of Sex Hormones on Ocular Blood Flow and Intraocular Pressure in Primary Open-angle Glaucoma: A Review

Patel, P., Harris, A., Toris, C., Tobe, L., Lang, M., Belamkar, A., Ng, A., Verticchio Vercellin, A. C., Mathew, S. & Siesky, B., Dec 1 2018, In : Journal of Glaucoma. 27, 12, p. 1037-1041 5 p.

Research output: Contribution to journalReview article

5 Scopus citations

Quantitative proteomic analysis of human aqueous humor using iTRAQ 4plex labeling

Trzeciecka, A., Pattabiraman, P., Piqueras, M. C., Toris, C. & Bhattacharya, S. K., 2018, Methods in Molecular Biology. Humana Press Inc., p. 89-95 7 p. (Methods in Molecular Biology; vol. 1695).

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Shotgun sphingolipid analysis of human aqueous humor

Trzeciecka, A., Arbelo, U., Barron, A., Edwards, G., Sampathkumar, S., Toris, C. & Bhattacharya, S. K., 2018, Methods in Molecular Biology. Humana Press Inc., p. 97-107 11 p. (Methods in Molecular Biology; vol. 1695).

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations
2017

Aqueous humour dynamics and biometrics in the ageing Chinese eye

Guo, T., Sampathkumar, S., Fan, S., Morris, N., Wang, F. & Toris, C. B., Sep 2017, In : British Journal of Ophthalmology. 101, 9, p. 1290-1296 7 p.

Research output: Contribution to journalArticle

4 Scopus citations

Comparison of aqueous outflow facility measurement by pneumatonography and digital schiøtz tonography

Kazemi, A., McLaren, J. W., Lin, S. C., Toris, C. B., Gulati, V., Moroi, S. E. & Sit, A. J., Jan 1 2017, In : Investigative Ophthalmology and Visual Science. 58, 1, p. 204-210 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

Making Basic Science Studies in Glaucoma More Clinically Relevant: The Need for a Consensus

Toris, C. B., Gelfman, C., Whitlock, A., Sponsel, W. E. & Rowe-Rendleman, C. L., Sep 2017, In : Journal of Ocular Pharmacology and Therapeutics. 33, 7, p. 501-518 18 p.

Research output: Contribution to journalReview article

5 Scopus citations

Mechanism of action of selective laser trabeculoplasty and predictors of response

Gulati, V., Fan, S., Gardner, B. J., Havens, S. J., Schaaf, M. T., Neely, D. G. & Toris, C. B., Mar 2017, In : Investigative Ophthalmology and Visual Science. 58, 3, p. 1462-1468 7 p.

Research output: Contribution to journalArticle

13 Scopus citations
2016

Aqueous flow measured by fluorophotometry in the mouse

Toris, C. B., Fan, S., Johnson, T. V., Camras, L. J., Hays, C. L., Liu, H. & Ishimoto, B. M., Jul 2016, In : Investigative Ophthalmology and Visual Science. 57, 8, p. 3844-3852 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

A Schlemm’s canal scaffold for the treatment of elevated IOP

Sampathkumar, S., Schieber, A. T. & Toris, C. B., Jul 3 2016, In : Expert Review of Ophthalmology. 11, 4, p. 259-266 8 p.

Research output: Contribution to journalReview article

2 Scopus citations

Effects of rho kinase inhibitors on intraocular pressure and aqueous humor dynamics in nonhuman primates and rabbits

Toris, C. B., McLaughlin, M. A., Dworak, D. P., Fan, S., Havens, S., Zhan, G. L., Horan, N. & Prasanna, G., Jul 1 2016, In : Journal of Ocular Pharmacology and Therapeutics. 32, 6, p. 355-364 10 p.

Research output: Contribution to journalArticle

12 Scopus citations

Prostanoid Receptor Antagonist Effects on Intraocular Pressure, Supported by Ocular Biodisposition Experiments

Woodward, D. F., Wenthur, S. L., Rudebush, T. L., Fan, S. & Toris, C. B., Nov 1 2016, In : Journal of Ocular Pharmacology and Therapeutics. 32, 9, p. 606-622 17 p.

Research output: Contribution to journalArticle

5 Scopus citations
10 Scopus citations
2015

A Novel Schlemm's Canal Scaffold: Histologic Observations

Grierson, I., Saheb, H., Kahook, M. Y., Johnstone, M. A., Ahmed, I. I. K., Schieber, A. T. & Toris, C. B., Aug 19 2015, In : Journal of Glaucoma. 24, 6, p. 460-468 9 p.

Research output: Contribution to journalReview article

13 Scopus citations

Aqueous Humor Dynamics and Intraocular Pressure Elevation

Toris, C. B., 2015, Medical Diagnosis and Therapy. Elsevier Inc., Vol. 1. p. 47-56 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations

Continuous non-cell autonomous reprogramming to generate retinal ganglion cells for glaucomatous neuropathy

Parameswaran, S., Dravid, S. M., Teotia, P., Krishnamoorthy, R. R., Qiu, F., Toris, C., Morrison, J. & Ahmad, I., Jun 1 2015, In : STEM CELLS. 33, 6, p. 1743-1758 16 p.

Research output: Contribution to journalArticle

9 Scopus citations

Intraocular pressure–lowering activity of NCX 470, a novel nitric oxide–donating bimatoprost in preclinical models

Impagnatiello, F., Toris, C. B., Batugo, M., Prasanna, G., Borghi, V., Bastia, E., Ongini, E. & Krauss, A. H. P., 2015, In : Investigative Ophthalmology and Visual Science. 56, 11, p. 6558-6564 7 p.

Research output: Contribution to journalArticle

10 Scopus citations
2014

Daytime and nighttime effects of brimonidine on IOP and aqueous humor dynamics in participants with ocular hypertension

Fan, S., Agrawal, A., Gulati, V., Neely, D. G. & Toris, C. B., 2014, In : Journal of Glaucoma. 23, 5, p. 276-281 6 p.

Research output: Contribution to journalArticle

11 Scopus citations

Effects of a Schlemm canal scaffold on collector channel ostia in human anterior segments

Johnstone, M. A., Saheb, H., Ahmed, I. I. K., Samuelson, T. W., Schieber, A. T. & Toris, C. B., Feb 2014, In : Experimental Eye Research. 119, p. 70-76 7 p.

Research output: Contribution to journalArticle

16 Scopus citations

FR-190997, a nonpeptide bradykinin B2-receptor partial agonist, is a potent and efficacious intraocular pressure lowering agent in ocular hypertensive cynomolgus monkeys

Sharif, N. A., Katoli, P., Scott, D., Li, L., Kelly, C., Xu, S., Husain, S., Toris, C. & Crosson, C., Jun 2014, In : Drug Development Research. 75, 4, p. 211-223 13 p.

Research output: Contribution to journalArticle

4 Scopus citations

Improvement in outflow facility by two novel microinvasive glaucoma surgery implants

Hays, C. L., Gulati, V., Fan, S., Samuelson, T. W., Ahmed, I. I. K. & Toris, C. B., 2014, In : Investigative Ophthalmology and Visual Science. 55, 3, p. 1893-1900 8 p.

Research output: Contribution to journalArticle

17 Scopus citations
2013
2 Scopus citations

A novel 8-mm Schlemm's canal scaffold reduces outflow resistance in a human anterior segment perfusion model

Gulati, V., Fan, S., Hays, C. L., Samuelson, T. W., Ahmed, I. I. K. & Toris, C. B., 2013, In : Investigative Ophthalmology and Visual Science. 54, 3, p. 1698-1704 7 p.

Research output: Contribution to journalArticle

24 Scopus citations

Current status of unoprostone for the management of glaucoma and the future of its use in the treatment of retinal disease

Harms, N. V. & Toris, C. B., Jan 2013, In : Expert Opinion on Pharmacotherapy. 14, 1, p. 105-113 9 p.

Research output: Contribution to journalReview article

6 Scopus citations

Molecular biomarkers in glaucoma

Seventh ARVO/Pfizer Ophthalmics Research Institute Conference Working Group, Jan 1 2013, In : Investigative Ophthalmology and Visual Science. 54, 1, p. 121-131 11 p.

Research output: Contribution to journalArticle

25 Scopus citations
2012

A novel schlemm's canal scaffold increases outflow facility in a human anterior segment perfusion model

Camras, L. J., Yuan, F., Fan, S., Samuelson, T. W., Ahmed, I. K., Schieber, A. T. & Toris, C. B., Sep 2012, In : Investigative Ophthalmology and Visual Science. 53, 10, p. 6115-6121 7 p.

Research output: Contribution to journalArticle

39 Scopus citations

Diurnal and nocturnal variations in aqueous humor dynamics of patients with ocular hypertension undergoing medical therapy

Gulati, V., Fan, S., Zhao, M., Maslonka, M. A., Gangahar, C. & Toris, C. B., Jun 2012, In : Archives of Ophthalmology. 130, 6, p. 677-684 8 p.

Research output: Contribution to journalArticle

30 Scopus citations
2011

Aqueous humor dynamics during the day and night in healthy mature volunteers

Liu, H., Fan, S., Gulati, V., Camras, L. J., Zhan, G., Ghate, D., Camras, C. B. & Toris, C. B., Mar 2011, In : Archives of Ophthalmology. 129, 3, p. 269-275 7 p.

Research output: Contribution to journalArticle

30 Scopus citations

Aqueous humor dynamics during the day and night in volunteers with ocular hypertension

Fan, S., Hejkal, J. J., Gulati, V., Galata, S., Camras, C. B. & Toris, C. B., Sep 2011, In : Archives of Ophthalmology. 129, 9, p. 1162-1166 5 p.

Research output: Contribution to journalArticle

11 Scopus citations

Assumption constraints of fluorophotometry in human eyes

Gulati, V. & Toris, C. B., Mar 2011, In : Investigative Ophthalmology and Visual Science. 52, 3, p. 1312-1313 2 p.

Research output: Contribution to journalLetter

3 Scopus citations
4 Scopus citations

Effect of PF-04217329 a prodrug of a selective prostaglandin EP 2 agonist on intraocular pressure in preclinical models of glaucoma

Prasanna, G., Carreiro, S., Anderson, S., Gukasyan, H., Sartnurak, S., Younis, H., Gale, D., Xiang, C., Wells, P., Dinh, D., Almaden, C., Fortner, J., Toris, C., Niesman, M., Lafontaine, J. & Krauss, A., Sep 2011, In : Experimental Eye Research. 93, 3, p. 256-264 9 p.

Research output: Contribution to journalArticle

30 Scopus citations

Foreword

Toris, C. B. & Quigley, H. A., Sep 2011, In : Experimental Eye Research. 93, 3, p. 238 1 p.

Research output: Contribution to journalEditorial

Ocular hypotensive activity of BOL-303259-X, a nitric oxide donating Prostaglandin F2α agonist, in preclinical models

Krauss, A. H. P., Impagnatiello, F., Toris, C. B., Gale, D. C., Prasanna, G., Borghi, V., Chiroli, V., Chong, W. K. M., Carreiro, S. T. & Ongini, E., Sep 2011, In : Experimental Eye Research. 93, 3, p. 250-255 6 p.

Research output: Contribution to journalArticle

67 Scopus citations

Reflections on the life and career of Carl Camras

Toris, C. B., Gulati, V., Reid, T. & Quigley, H., Sep 2011, In : Experimental Eye Research. 93, 3, p. 239-242 4 p.

Research output: Contribution to journalEditorial

Regulation of ocular angiogenesis by notch signaling: Implications in neovascular age-related macular degeneration

Ahmad, I., Balasubramanian, S., del Debbio, C. B., Parameswaran, S., Katz, A. R., Toris, C. & Fariss, R. N., May 2011, In : Investigative Ophthalmology and Visual Science. 52, 6, p. 2868-2878 11 p.

Research output: Contribution to journalArticle

35 Scopus citations

The biology, pathology and therapeutic use of prostaglandins in the eye

Toris, C. B. & Gulati, V., Oct 2011, In : Clinical Lipidology. 6, 5, p. 577-591 15 p.

Research output: Contribution to journalReview article

5 Scopus citations
2010

A novel nitric oxide releasing prostaglandin analog, NCX 125, reduces intraocular pressure in rabbit, dog, and primate models of glaucoma

Borghi, V., Bastia, E., Guzzetta, M., Chiroli, V., Toris, C. B., Batugo, M. R., Carreiro, S. T., Chong, W. K. M., Gale, D. C., Kucera, D. J., Jia, L., Prasanna, G., Ongini, E., Krauss, A. H. P. & Impagnatiello, F., Apr 1 2010, In : Journal of Ocular Pharmacology and Therapeutics. 26, 2, p. 125-131 7 p.

Research output: Contribution to journalArticle

54 Scopus citations

Aqueous humor dynamics during the day and night in juvenile and adult rabbits

Zhao, M., Hejkal, J. J., Camras, C. B. & Toris, C. B., Jun 2010, In : Investigative Ophthalmology and Visual Science. 51, 6, p. 3145-3151 7 p.

Research output: Contribution to journalArticle

16 Scopus citations

Aqueous humor dynamics in inbred rhesus monkeys with naturally occurring ocular hypertension

Toris, C. B., Risma, J. M., Gonzales-Martinez, J., McLaughlin, M. A. & Dawson, W. W., Dec 2010, In : Experimental Eye Research. 91, 6, p. 860-865 6 p.

Research output: Contribution to journalArticle

5 Scopus citations