Concetta C DiRusso

  • 3981 Citations
  • 36 h-Index
1977 …2020

Research output per year

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Research Output

2020

Deletion of fatty acid transport protein 2 (FATP2) in the mouse liver changes the metabolic landscape by increasing the expression of PPARα-regulated genes

Perez, V. M., Gabell, J., Behrens, M., Wase, N., DiRusso, C. C. & Black, P. N., Apr 24 2020, In : Journal of Biological Chemistry. 295, 17, p. 5737-5750 14 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Healthy pregnancies and essential fats: Focus group discussions with Zambian women on dietary need and acceptability of a novel RUSF containing fish oil DHA

Chunda-Liyoka, C., Lubeya, M. K., Imakando, M., Kisling, S., Majid, S., Willis, M. S., Wood, C., Kankasa, C. & Dirusso, C. C., Feb 10 2020, In : BMC Pregnancy and Childbirth. 20, 1, 93.

Research output: Contribution to journalArticle

Open Access
Open Access
2019

Fatty acid transport protein 2 reprograms neutrophils in cancer

Veglia, F., Tyurin, V. A., Blasi, M., De Leo, A., Kossenkov, A. V., Donthireddy, L., To, T. K. J., Schug, Z., Basu, S., Wang, F., Ricciotti, E., DiRusso, C., Murphy, M. E., Vonderheide, R. H., Lieberman, P. M., Mulligan, C., Nam, B., Hockstein, N., Masters, G., Guarino, M. & 5 others, Lin, C., Nefedova, Y., Black, P., Kagan, V. E. & Gabrilovich, D. I., May 2 2019, In : Nature. 569, 7754, p. 73-78 6 p.

Research output: Contribution to journalArticle

43 Scopus citations

Remodeling of chlamydomonas metabolism using synthetic inducers results in lipid storage during growth

Wase, N., Tu, B., Rasineni, G. K., Cerny, R., Grove, R., Adamec, J., Black, P. N. & DiRusso, C. C., Nov 2019, In : Plant physiology. 181, 3, p. 1029-1049 21 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Transcriptome analysis-identified long noncoding RNA CRNDE in maintaining endothelial cell proliferation, migration, and tube formation

Moran, M., Cheng, X., Shihabudeen Haider Ali, M. S., Wase, N., Nguyen, N., Yang, W., Zhang, C., DiRusso, C. & Sun, X., Dec 1 2019, In : Scientific reports. 9, 1, 19548.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2018

Combining Mass Spectrometry and NMR Improves Metabolite Detection and Annotation

Bhinderwala, F., Wase, N., Dirusso, C. & Powers, R., Nov 2 2018, In : Journal of proteome research. 17, 11, p. 4017-4022 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

Dietary omega-3 and omega-6 polyunsaturated fatty acids modulate hepatic pathology

Khadge, S., Sharp, J. G., Thiele, G. M., McGuire, T. R., Klassen, L. W., Duryee, M. J., Britton, H. C., Dafferner, A. J., Beck, J., Black, P. N., DiRusso, C. C. & Talmadge, J. E., Feb 2018, In : Journal of Nutritional Biochemistry. 52, p. 92-102 11 p.

Research output: Contribution to journalArticle

11 Scopus citations
5 Scopus citations

Induction of oil accumulation by heat stress is metabolically distinct from N stress in the green microalgae Coccomyxa subellipsoidea C169

Allen, J. W., Tevatia, R., Demirel, Y., DiRusso, C. C. & Black, P. N., Sep 2018, In : PloS one. 13, 9, e0204505.

Research output: Contribution to journalArticle

4 Scopus citations

Innovations in improving lipid production: Algal chemical genetics

Wase, N., Black, P. & DiRusso, C., Jul 2018, In : Progress in Lipid Research. 71, p. 101-123 23 p.

Research output: Contribution to journalReview article

7 Scopus citations
10 Scopus citations
4 Scopus citations
2017
8 Scopus citations

Identification and metabolite profiling of chemical activators of lipid accumulation in green algae

Wase, N., Tu, B., Allen, J. W., Black, P. N. & DiRusso, C. C., Aug 2 2017, In : Plant physiology. 174, 4, p. 2146-2165 20 p.

Research output: Contribution to journalArticle

14 Scopus citations
2016

Fatty acid transport proteins: Targeting FATP2 as a gatekeeper involved in the transport of exogenous fatty acids

Black, P. N., Ahowesso, C., Montefusco, D., Saini, N. & Dirusso, C. C., Apr 1 2016, In : MedChemComm. 7, 4, p. 612-622 11 p.

Research output: Contribution to journalReview article

18 Scopus citations
2015

Chemical inhibition of fatty acid absorption and cellular uptake limits lipotoxic cell death

Ahowesso, C., Black, P. N., Saini, N., Montefusco, D., Chekal, J., Malosh, C., Lindsley, C. W., Stauffer, S. R. & DiRusso, C. C., Nov 1 2015, In : Biochemical Pharmacology. 98, 1, p. 167-181 15 p.

Research output: Contribution to journalArticle

13 Scopus citations
5 Scopus citations
9 Scopus citations
30 Scopus citations
2014

Integrated quantitative analysis of nitrogen stress response in Chlamydomonas reinhardtii using metabolite and protein profiling

Wase, N., Black, P. N., Stanley, B. A. & Dirusso, C. C., Mar 7 2014, In : Journal of proteome research. 13, 3, p. 1373-1396 24 p.

Research output: Contribution to journalArticle

91 Scopus citations
11 Scopus citations
2013
18 Scopus citations

Rapid detection and quantification of triacylglycerol by HPLC-ELSD in chlamydomonas reinhardtii and chlorella strains

Kobayashi, N., Noel, E. A., Barnes, A., Rosenberg, J., Dirusso, C., Black, P. & Oyler, G. A., Oct 2013, In : Lipids. 48, 10, p. 1035-1049 15 p.

Research output: Contribution to journalArticle

18 Scopus citations
2012

Erratum: Identification and characterization of small compound inhibitors of human FATP2 (Biochemical Pharmacology (2010) 79 (990-999))

Sandoval, A., Chokshi, A., Jesch, E. D., Black, P. N. & Dirusso, C. C., Aug 15 2012, In : Biochemical Pharmacology. 84, 4, 1 p.

Research output: Contribution to journalComment/debate

2011

Defining a relationship between dietary fatty acids and the cytochrome P450 system in a mouse model of fatty liver disease

Gonzalez, M., Sealls, W., Jesch, E. D., Brosnan, M. J., Ladunga, I., Ding, X., Black, P. N. & DiRusso, C. C., Feb 2011, In : Physiological genomics. 43, 3, p. 121-135 15 p.

Research output: Contribution to journalArticle

13 Scopus citations
27 Scopus citations
2010

Identification and characterization of small compound inhibitors of human FATP2

Sandoval, A., Chokshi, A., Jesch, E. D., Black, P. N. & DiRusso, C. C., Apr 1 2010, In : Biochemical Pharmacology. 79, 7, p. 990-999 10 p.

Research output: Contribution to journalArticle

17 Scopus citations
2009

Dietary lipid absorption

DiRusso, C. C. & Black, P. N., 2009, In : Immunology, Endocrine and Metabolic Agents in Medicinal Chemistry. 9, 1, p. 1-2 2 p.

Research output: Contribution to journalEditorial

Methods to monitor Fatty Acid transport proceeding through vectorial acylation.

Arias-Barrau, E., Dirusso, C. C. & Black, P. N., 2009, In : Methods in molecular biology (Clifton, N.J.). 580, p. 233-249 17 p.

Research output: Contribution to journalArticle

12 Scopus citations
19 Scopus citations
2008

Dietary polyunsaturated fatty acids (C18:2 ω6 and C18:3 ω3) do not suppress hepatic lipogenesis

Sealls, W., Gonzalez, M., Brosnan, M. J., Black, P. N. & DiRusso, C. C., Aug 2008, In : Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1781, 8, p. 406-414 9 p.

Research output: Contribution to journalArticle

25 Scopus citations

Fatty acid transport and activation and the expression patterns of genes involved in fatty acid trafficking

Sandoval, A., Fraisl, P., Arias-Barrau, E., DiRusso, C. C., Singer, D., Sealls, W. & Black, P. N., Sep 15 2008, In : Archives of Biochemistry and Biophysics. 477, 2, p. 363-371 9 p.

Research output: Contribution to journalArticle

44 Scopus citations

Functional domains of the fatty acid transport proteins: Studies using protein chimeras

DiRusso, C. C., Darwis, D., Obermeyer, T. & Black, P. N., Mar 2008, In : Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1781, 3, p. 135-143 9 p.

Research output: Contribution to journalArticle

31 Scopus citations

High-throughput screening for fatty acid uptake inhibitors in humanized yeast identifies atypical antipsychotic drugs that cause dyslipidemias

Li, H., Black, P. N., Chokshi, A., Sandoval-Alvarez, A., Vatsyayan, R., Sealls, W. & DiRusso, C. C., Jan 2008, In : Journal of Lipid Research. 49, 1, p. 230-244 15 p.

Research output: Contribution to journalArticle

21 Scopus citations

Mechanistic studies of the long chain acyl-CoA synthetase Faa1p from Saccharomyces cerevisiae

Li, H., Melton, E. M., Quackenbush, S., DiRusso, C. C. & Black, P. N., Sep 2007, In : Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1771, 9, p. 1246-1253 8 p.

Research output: Contribution to journalArticle

15 Scopus citations
20 Scopus citations

Vectorial acylation: Linking fatty acid transport and activation to metabolic trafficking

Black, P. N. & DiRusso, C. C., 2007, Fatty Acids and Lipotoxicity in Obesity and Diabetes. p. 127-138 12 p. (Novartis Foundation Symposium; vol. 286).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

27 Scopus citations
132 Scopus citations
2006

Direct interaction of Saccharomyces cerevisiae Faa1p with the Omi/HtrA protease orthologue Ynm3p alters lipid homeostasis

Tong, F., Black, P. N., Bivins, L., Quackenbush, S., Ctrnacta, V. & DiRusso, C. C., Apr 2006, In : Molecular Genetics and Genomics. 275, 4, p. 330-343 14 p.

Research output: Contribution to journalArticle

13 Scopus citations
36 Scopus citations
2005

A live-cell high-throughput screening assay for identification of fatty acid uptake inhibitors

Li, H., Black, P. N. & Dirusso, C. C., Jan 1 2005, In : Analytical Biochemistry. 336, 1, p. 11-19 9 p.

Research output: Contribution to journalArticle

33 Scopus citations

Comparative biochemical studies of the murine fatty acid transport proteins (FATP) expressed in yeast

DiRusso, C. C., Li, H., Darwis, D., Watkins, P. A., Berger, J. & Black, P. N., Apr 29 2005, In : Journal of Biological Chemistry. 280, 17, p. 16829-16837 9 p.

Research output: Contribution to journalArticle

103 Scopus citations
50 Scopus citations

Long-chain acyl-CoA synthetase 6 preferentially promotes DHA metabolism

Marszalek, J. R., Kitidis, C., DiRusso, C. C. & Lodish, H. F., Mar 18 2005, In : Journal of Biological Chemistry. 280, 11, p. 10817-10826 10 p.

Research output: Contribution to journalArticle

75 Scopus citations
2004

Bacterial long chain fatty acid transport: Gateway to a fatty acid-responsive signaling system

Dirusso, C. C. & Black, P. N., Nov 26 2004, In : Journal of Biological Chemistry. 279, 48, p. 49563-49566 4 p.

Research output: Contribution to journalShort survey

68 Scopus citations

Rat Long Chain Acyl-CoA Synthetase 5, but Not 1, 2, 3, or 4, Complements Escherichia coli fadD

Caviglia, J. M., Li, L. O., Wang, S., DiRusso, C. C., Coleman, R. A. & Lewin, T. M., Mar 19 2004, In : Journal of Biological Chemistry. 279, 12, p. 11163-11169 7 p.

Research output: Contribution to journalArticle

18 Scopus citations

Revised nomenclature for the mammalian long-chain acyl-CoA synthetase gene family

Mashek, D. G., Bornfeldt, K. E., Coleman, R. A., Berger, J., Bernlohr, D. A., Black, P., DiRusso, C. C., Farber, S. A., Guo, W., Hashimoto, N., Khodiyar, V., Kuypers, F. A., Maltais, L. J., Nebert, D. W., Renieri, A., Schaffer, J. E., Stahl, A., Watkins, P. A., Vasiliou, V. & Yamamoto, T. T., Oct 2004, In : Journal of Lipid Research. 45, 10, p. 1958-1961 4 p.

Research output: Contribution to journalArticle

113 Scopus citations
2003
152 Scopus citations