Concetta C DiRusso

  • 3981 Citations
  • 36 h-Index
1977 …2020

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Article
2020

Deletion of fatty acid transport protein 2 (FATP2) in the mouse liver changes the metabolic landscape by increasing the expression of PPARα-regulated genes

Perez, V. M., Gabell, J., Behrens, M., Wase, N., DiRusso, C. C. & Black, P. N., Apr 24 2020, In : Journal of Biological Chemistry. 295, 17, p. 5737-5750 14 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Healthy pregnancies and essential fats: Focus group discussions with Zambian women on dietary need and acceptability of a novel RUSF containing fish oil DHA

Chunda-Liyoka, C., Lubeya, M. K., Imakando, M., Kisling, S., Majid, S., Willis, M. S., Wood, C., Kankasa, C. & Dirusso, C. C., Feb 10 2020, In : BMC Pregnancy and Childbirth. 20, 1, 93.

Research output: Contribution to journalArticle

Open Access
Open Access
2019

Fatty acid transport protein 2 reprograms neutrophils in cancer

Veglia, F., Tyurin, V. A., Blasi, M., De Leo, A., Kossenkov, A. V., Donthireddy, L., To, T. K. J., Schug, Z., Basu, S., Wang, F., Ricciotti, E., DiRusso, C., Murphy, M. E., Vonderheide, R. H., Lieberman, P. M., Mulligan, C., Nam, B., Hockstein, N., Masters, G., Guarino, M. & 5 others, Lin, C., Nefedova, Y., Black, P., Kagan, V. E. & Gabrilovich, D. I., May 2 2019, In : Nature. 569, 7754, p. 73-78 6 p.

Research output: Contribution to journalArticle

43 Scopus citations

Remodeling of chlamydomonas metabolism using synthetic inducers results in lipid storage during growth

Wase, N., Tu, B., Rasineni, G. K., Cerny, R., Grove, R., Adamec, J., Black, P. N. & DiRusso, C. C., Nov 2019, In : Plant physiology. 181, 3, p. 1029-1049 21 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Transcriptome analysis-identified long noncoding RNA CRNDE in maintaining endothelial cell proliferation, migration, and tube formation

Moran, M., Cheng, X., Shihabudeen Haider Ali, M. S., Wase, N., Nguyen, N., Yang, W., Zhang, C., DiRusso, C. & Sun, X., Dec 1 2019, In : Scientific reports. 9, 1, 19548.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2018

Combining Mass Spectrometry and NMR Improves Metabolite Detection and Annotation

Bhinderwala, F., Wase, N., Dirusso, C. & Powers, R., Nov 2 2018, In : Journal of proteome research. 17, 11, p. 4017-4022 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

Dietary omega-3 and omega-6 polyunsaturated fatty acids modulate hepatic pathology

Khadge, S., Sharp, J. G., Thiele, G. M., McGuire, T. R., Klassen, L. W., Duryee, M. J., Britton, H. C., Dafferner, A. J., Beck, J., Black, P. N., DiRusso, C. C. & Talmadge, J. E., Feb 2018, In : Journal of Nutritional Biochemistry. 52, p. 92-102 11 p.

Research output: Contribution to journalArticle

11 Scopus citations

Induction of oil accumulation by heat stress is metabolically distinct from N stress in the green microalgae Coccomyxa subellipsoidea C169

Allen, J. W., Tevatia, R., Demirel, Y., DiRusso, C. C. & Black, P. N., Sep 2018, In : PloS one. 13, 9, e0204505.

Research output: Contribution to journalArticle

4 Scopus citations
10 Scopus citations
4 Scopus citations
2017
8 Scopus citations

Identification and metabolite profiling of chemical activators of lipid accumulation in green algae

Wase, N., Tu, B., Allen, J. W., Black, P. N. & DiRusso, C. C., Aug 2 2017, In : Plant physiology. 174, 4, p. 2146-2165 20 p.

Research output: Contribution to journalArticle

14 Scopus citations
2015

Chemical inhibition of fatty acid absorption and cellular uptake limits lipotoxic cell death

Ahowesso, C., Black, P. N., Saini, N., Montefusco, D., Chekal, J., Malosh, C., Lindsley, C. W., Stauffer, S. R. & DiRusso, C. C., Nov 1 2015, In : Biochemical Pharmacology. 98, 1, p. 167-181 15 p.

Research output: Contribution to journalArticle

13 Scopus citations
5 Scopus citations
9 Scopus citations
30 Scopus citations
2014

Integrated quantitative analysis of nitrogen stress response in Chlamydomonas reinhardtii using metabolite and protein profiling

Wase, N., Black, P. N., Stanley, B. A. & Dirusso, C. C., Mar 7 2014, In : Journal of proteome research. 13, 3, p. 1373-1396 24 p.

Research output: Contribution to journalArticle

91 Scopus citations
11 Scopus citations
2013
18 Scopus citations

Rapid detection and quantification of triacylglycerol by HPLC-ELSD in chlamydomonas reinhardtii and chlorella strains

Kobayashi, N., Noel, E. A., Barnes, A., Rosenberg, J., Dirusso, C., Black, P. & Oyler, G. A., Oct 2013, In : Lipids. 48, 10, p. 1035-1049 15 p.

Research output: Contribution to journalArticle

18 Scopus citations
2011

Defining a relationship between dietary fatty acids and the cytochrome P450 system in a mouse model of fatty liver disease

Gonzalez, M., Sealls, W., Jesch, E. D., Brosnan, M. J., Ladunga, I., Ding, X., Black, P. N. & DiRusso, C. C., Feb 2011, In : Physiological genomics. 43, 3, p. 121-135 15 p.

Research output: Contribution to journalArticle

13 Scopus citations
27 Scopus citations
2010

Identification and characterization of small compound inhibitors of human FATP2

Sandoval, A., Chokshi, A., Jesch, E. D., Black, P. N. & DiRusso, C. C., Apr 1 2010, In : Biochemical Pharmacology. 79, 7, p. 990-999 10 p.

Research output: Contribution to journalArticle

17 Scopus citations
2009

Methods to monitor Fatty Acid transport proceeding through vectorial acylation.

Arias-Barrau, E., Dirusso, C. C. & Black, P. N., 2009, In : Methods in molecular biology (Clifton, N.J.). 580, p. 233-249 17 p.

Research output: Contribution to journalArticle

12 Scopus citations
2008

Dietary polyunsaturated fatty acids (C18:2 ω6 and C18:3 ω3) do not suppress hepatic lipogenesis

Sealls, W., Gonzalez, M., Brosnan, M. J., Black, P. N. & DiRusso, C. C., Aug 2008, In : Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1781, 8, p. 406-414 9 p.

Research output: Contribution to journalArticle

25 Scopus citations

Fatty acid transport and activation and the expression patterns of genes involved in fatty acid trafficking

Sandoval, A., Fraisl, P., Arias-Barrau, E., DiRusso, C. C., Singer, D., Sealls, W. & Black, P. N., Sep 15 2008, In : Archives of Biochemistry and Biophysics. 477, 2, p. 363-371 9 p.

Research output: Contribution to journalArticle

44 Scopus citations

Functional domains of the fatty acid transport proteins: Studies using protein chimeras

DiRusso, C. C., Darwis, D., Obermeyer, T. & Black, P. N., Mar 2008, In : Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1781, 3, p. 135-143 9 p.

Research output: Contribution to journalArticle

31 Scopus citations

High-throughput screening for fatty acid uptake inhibitors in humanized yeast identifies atypical antipsychotic drugs that cause dyslipidemias

Li, H., Black, P. N., Chokshi, A., Sandoval-Alvarez, A., Vatsyayan, R., Sealls, W. & DiRusso, C. C., Jan 2008, In : Journal of Lipid Research. 49, 1, p. 230-244 15 p.

Research output: Contribution to journalArticle

21 Scopus citations
2007

Mechanistic studies of the long chain acyl-CoA synthetase Faa1p from Saccharomyces cerevisiae

Li, H., Melton, E. M., Quackenbush, S., DiRusso, C. C. & Black, P. N., Sep 2007, In : Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1771, 9, p. 1246-1253 8 p.

Research output: Contribution to journalArticle

15 Scopus citations
20 Scopus citations
2006

Direct interaction of Saccharomyces cerevisiae Faa1p with the Omi/HtrA protease orthologue Ynm3p alters lipid homeostasis

Tong, F., Black, P. N., Bivins, L., Quackenbush, S., Ctrnacta, V. & DiRusso, C. C., Apr 2006, In : Molecular Genetics and Genomics. 275, 4, p. 330-343 14 p.

Research output: Contribution to journalArticle

13 Scopus citations
36 Scopus citations
2005

A live-cell high-throughput screening assay for identification of fatty acid uptake inhibitors

Li, H., Black, P. N. & Dirusso, C. C., Jan 1 2005, In : Analytical Biochemistry. 336, 1, p. 11-19 9 p.

Research output: Contribution to journalArticle

33 Scopus citations

Comparative biochemical studies of the murine fatty acid transport proteins (FATP) expressed in yeast

DiRusso, C. C., Li, H., Darwis, D., Watkins, P. A., Berger, J. & Black, P. N., Apr 29 2005, In : Journal of Biological Chemistry. 280, 17, p. 16829-16837 9 p.

Research output: Contribution to journalArticle

103 Scopus citations
50 Scopus citations

Long-chain acyl-CoA synthetase 6 preferentially promotes DHA metabolism

Marszalek, J. R., Kitidis, C., DiRusso, C. C. & Lodish, H. F., Mar 18 2005, In : Journal of Biological Chemistry. 280, 11, p. 10817-10826 10 p.

Research output: Contribution to journalArticle

75 Scopus citations
2004

Rat Long Chain Acyl-CoA Synthetase 5, but Not 1, 2, 3, or 4, Complements Escherichia coli fadD

Caviglia, J. M., Li, L. O., Wang, S., DiRusso, C. C., Coleman, R. A. & Lewin, T. M., Mar 19 2004, In : Journal of Biological Chemistry. 279, 12, p. 11163-11169 7 p.

Research output: Contribution to journalArticle

18 Scopus citations

Revised nomenclature for the mammalian long-chain acyl-CoA synthetase gene family

Mashek, D. G., Bornfeldt, K. E., Coleman, R. A., Berger, J., Bernlohr, D. A., Black, P., DiRusso, C. C., Farber, S. A., Guo, W., Hashimoto, N., Khodiyar, V., Kuypers, F. A., Maltais, L. J., Nebert, D. W., Renieri, A., Schaffer, J. E., Stahl, A., Watkins, P. A., Vasiliou, V. & Yamamoto, T. T., Oct 2004, In : Journal of Lipid Research. 45, 10, p. 1958-1961 4 p.

Research output: Contribution to journalArticle

113 Scopus citations
2003

Vectorial acylation in Saccharomyces cerevisiae: Fat1p and fatty acyl-CoA synthetase are interacting components of a fatty acid import complex

Zou, Z., Tong, F., Færgeman, N. J., Børsting, C., Black, P. N. & DiRusso, C. C., May 2 2003, In : Journal of Biological Chemistry. 278, 18, p. 16414-16422 9 p.

Research output: Contribution to journalArticle

81 Scopus citations
2002
88 Scopus citations
83 Scopus citations
2001
106 Scopus citations

The structural basis of acyl coenzyme A-dependent regulation of the transcription factor FadR

Van Aalten, D. M. F., DiRusso, C. C. & Knudsen, J., Apr 17 2001, In : EMBO Journal. 20, 8, p. 2041-2050 10 p.

Research output: Contribution to journalArticle

113 Scopus citations

Two different pathways are involved in the β-oxidation of n-alkanoic and n-phenylalkanoic acids in Pseudomonas putida U: Genetic studies and biotechnological applications

Olivera, E. R., Carnicero, D., García, B., Miñambres, B., Moreno, M. A., Cañedo, L., DiRusso, C. C., Naharro, G. & Luengo, J. M., 2001, In : Molecular Microbiology. 39, 4, p. 863-874 12 p.

Research output: Contribution to journalArticle

64 Scopus citations
2000

Affinity labeling fatty acyl-CoA synthetase with 9-p-azidophenoxy nonanoic acid and the identification of the fatty acid-binding site

Black, P. N., DiRusso, C. C., Sherin, D., MacColl, R., Knudsen, J. & Weimar, J. D., Dec 8 2000, In : Journal of Biological Chemistry. 275, 49, p. 38547-38553 7 p.

Research output: Contribution to journalArticle

33 Scopus citations

Crystallization and X-ray diffraction studies of the fatty-acid responsive transcription factor FadR from Escherichia coli

Van Aalten, D. M. F., Knudsen, J., DiRusso, C. C., Kokko, T. & Wierenga, R. K., 2000, In : Acta Crystallographica Section D: Biological Crystallography. 56, 4, p. 469-471 3 p.

Research output: Contribution to journalArticle

6 Scopus citations

Crystal structure of FadR, a fatty acid-responsive transcription factor with a novel acyl coenzyme A-binding fold

Van Aalten, D. M. F., Dirusso, C. C., Knudsen, J. & Wierenga, R. K., Oct 2 2000, In : EMBO Journal. 19, 19, p. 5167-5177 11 p.

Research output: Contribution to journalArticle

Open Access
91 Scopus citations

Long-chain acyl-CoA-dependent regulation of gene expression in bacteria, yeast and mammals

Black, P. N., Færgeman, N. J. & DiRusso, C. C., 2000, In : Journal of Nutrition. 130, 2 SUPPL., p. 305S-309S

Research output: Contribution to journalArticle

Open Access
75 Scopus citations

Multiple factors independently regulate hilA and invasion gene expression in Salmonella enterica serovar typhimurium

Lucas, R. L., Lostroh, C. P., DiRusso, C. C., Spector, M. P., Wanner, B. L. & Lee, C. A., Apr 2000, In : Journal of bacteriology. 182, 7, p. 1872-1882 11 p.

Research output: Contribution to journalArticle

177 Scopus citations