• 3078 Citations
  • 31 h-Index
19992020

Research output per year

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Research Output

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Review article
2020

Selective α7 nicotinic receptor agonists and positive allosteric modulators for the treatment of schizophrenia–a review

Antonio-Tolentino, K. & Hopkins, C. R., Jun 2 2020, In : Expert Opinion on Investigational Drugs. 29, 6, p. 603-610 8 p.

Research output: Contribution to journalReview article

2019

Review of Transient Receptor Potential Canonical (TRPC5) Channel Modulators and Diseases

Sharma, S. & Hopkins, C. R., Sep 12 2019, In : Journal of Medicinal Chemistry. 62, 17, p. 7589-7602 14 p.

Research output: Contribution to journalReview article

5 Scopus citations
2017

Return of D4 Dopamine Receptor Antagonists in Drug Discovery

Lindsley, C. W. & Hopkins, C. R., 2017, In : Journal of Medicinal Chemistry. 60, 17, p. 7233-7243 11 p.

Research output: Contribution to journalReview article

17 Scopus citations
2016

Inhibitors of the bone morphogenetic protein (BMP) signaling pathway: a patent review (2008-2015)

Hopkins, C. R., Oct 2 2016, In : Expert Opinion on Therapeutic Patents. 26, 10, p. 1115-1128 14 p.

Research output: Contribution to journalReview article

11 Scopus citations

Practical Strategies and Concepts in GPCR Allosteric Modulator Discovery: Recent Advances with Metabotropic Glutamate Receptors

Lindsley, C. W., Emmitte, K. A., Hopkins, C. R., Bridges, T. M., Gregory, K. J., Niswender, C. M. & Conn, P. J., Jun 8 2016, In : Chemical Reviews. 116, 11, p. 6707-6741 35 p.

Research output: Contribution to journalReview article

100 Scopus citations
2015

Advancing biological understanding and therapeutics discovery with small-molecule probes

Schreiber, S. L., Kotz, J. D., Li, M., Aubé, J., Austin, C. P., Reed, J. C., Rosen, H., White, E. L., Sklar, L. A., Lindsley, C. W., Alexander, B. R., Bittker, J. A., Clemons, P. A., De Souza, A., Foley, M. A., Palmer, M., Shamji, A. F., Wawer, M. J., McManus, O., Wu, M. & 26 others, Zou, B., Yu, H., Golden, J. E., Schoenen, F. J., Simeonov, A., Jadhav, A., Jackson, M. R., Pinkerton, A. B., Chung, T. D. Y., Griffin, P. R., Cravatt, B. F., Hodder, P. S., Roush, W. R., Roberts, E., Chung, D. H., Jonsson, C. B., Noah, J. W., Severson, W. E., Ananthan, S., Edwards, B., Oprea, T. I., Conn, P. J., Hopkins, C. R., Wood, M. R., Stauffer, S. R. & Emmitte, K. A., 2015, In : Cell. 161, 6, p. 1252-1265 14 p.

Research output: Contribution to journalReview article

80 Scopus citations
2012

ACS chemical neuroscience molecule spotlight on begacestat (GSI-953)

Hopkins, C. R., Jan 18 2012, In : ACS Chemical Neuroscience. 3, 1, p. 3-4 2 p.

Research output: Contribution to journalReview article

25 Scopus citations

ACS chemical neuroscience molecule spotlight on BMS-708163

Hopkins, C. R., Mar 21 2012, In : ACS Chemical Neuroscience. 3, 3, p. 149-150 2 p.

Research output: Contribution to journalReview article

5 Scopus citations

ACS chemical neuroscience molecule spotlight on potiga (Ezogabine)

Hopkins, C. R., Aug 15 2012, In : ACS Chemical Neuroscience. 3, 8, p. 632 1 p.

Research output: Contribution to journalReview article

4 Scopus citations

ACS chemical neuroscience molecule spotlight on suvorexant

Hopkins, C. R., Sep 19 2012, In : ACS Chemical Neuroscience. 3, 9, p. 647-648 2 p.

Research output: Contribution to journalReview article

10 Scopus citations

Allosteric modulation of seven transmembrane spanning receptors: Theory, practice, and opportunities for central nervous system drug discovery

Melancon, B. J., Hopkins, C. R., Wood, M. R., Emmitte, K. A., Niswender, C. M., Christopoulos, A., Conn, P. J. & Lindsley, C. W., Feb 23 2012, In : Journal of Medicinal Chemistry. 55, 4, p. 1445-1464 20 p.

Research output: Contribution to journalReview article

169 Scopus citations
27 Scopus citations
2011

ACS chemical neuroscience molecule spotlight on ELND006: Another γ-secretase inhibitor fails in the clinic

Hopkins, C. R., Jun 15 2011, In : ACS Chemical Neuroscience. 2, 6, p. 279-280 2 p.

Research output: Contribution to journalReview article

34 Scopus citations

ACS chemical neuroscience molecule spotlight on STX209 (Arbaclofen)

Hopkins, C. R., Aug 17 2011, In : ACS Chemical Neuroscience. 2, 8, p. 381 1 p.

Research output: Contribution to journalReview article

3 Scopus citations

ACS chemical neuroscience molecule spotlight on telcagepant (MK-0974)

Hopkins, C. R., Jul 20 2011, In : ACS Chemical Neuroscience. 2, 7, p. 334-335 2 p.

Research output: Contribution to journalReview article

2 Scopus citations

Recent progress on the identification of metabotropic glutamate 4 receptor ligands and their potential utility as CNS therapeutics

Robichaud, A. J., Engers, D. W., Lindsley, C. W. & Hopkins, C. R., Aug 17 2011, In : ACS Chemical Neuroscience. 2, 8, p. 433-449 17 p.

Research output: Contribution to journalReview article

31 Scopus citations
2010

The antipsychotic potential of muscarinic allosteric modulation

Bridges, T. M., LeBois, E. P., Hopkins, C. R., Wood, M. R., Jones, C. K., Conn, P. J. & Lindsley, C. W., May 2010, In : Drug News and Perspectives. 23, 4, p. 229-240 12 p.

Research output: Contribution to journalReview article

48 Scopus citations
2009

MGluR4-positive allosteric modulation as potential treatment for Parkinson's disease

Hopkins, C. R., Lindsley, C. W. & Niswender, C. M., Jun 2009, In : Future Medicinal Chemistry. 1, 3, p. 501-513 13 p.

Research output: Contribution to journalReview article

52 Scopus citations

Recent progress in the development of mGluR4 positive allosteric modulators for the treatment of Parkinson's disease

Lindsley, C. W., Niswender, C. M., Engers, D. W. & Hopkins, C. R., 2009, In : Current Topics in Medicinal Chemistry. 9, 10, p. 949-963 15 p.

Research output: Contribution to journalReview article

35 Scopus citations
2008

Molecule of the month

Hopkins, C. R., 2008, In : Current Topics in Medicinal Chemistry. 8, 18, p. 1710-1711 2 p.

Research output: Contribution to journalReview article