Dahn L Clemens, PhD

  • 1913 Citations
  • 22 h-Index
1989 …2020

Research output per year

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Research Output

  • 1913 Citations
  • 22 h-Index
  • 57 Article
  • 4 Review article
  • 1 Chapter
  • 1 Comment/debate
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Article
2 Scopus citations

AKT proto-oncogene overexpression is an early event during sporadic colon carcinogenesis

Roy, H. K., Olusola, B. F., Clemens, D. L., Karolski, W. J., Ratashak, A., Lynch, H. T. & Smyrk, T. C., 2002, In : Carcinogenesis. 23, 1, p. 201-205 5 p.

Research output: Contribution to journalArticle

Open Access
276 Scopus citations

Alcoholic pancreatitis: Lessons from the liver

Clemens, D. L. & Mahan, K. J., Mar 21 2010, In : World Journal of Gastroenterology. 16, 11, p. 1314-1320 7 p.

Research output: Contribution to journalArticle

19 Scopus citations

Alcohol metabolism-mediated oxidative stress down-regulates hepcidin transcription and leads to increased duodenal iron transporter expression

Harrison-Findik, D. D., Schafer, D., Klein, E., Timchenko, N. A., Kulaksiz, H., Clemens, D., Fein, E., Andriopoulos, B., Pantopoulos, K. & Gollan, J., Aug 11 2006, In : Journal of Biological Chemistry. 281, 32, p. 22974-22982 9 p.

Research output: Contribution to journalArticle

203 Scopus citations

Animal Model of Alcoholic Pancreatitis: Role of Viral Infections

Jerrells, T. R., Chapman, N. & Clemens, D. L., Nov 2003, In : Pancreas. 27, 4, p. 301-304 4 p.

Research output: Contribution to journalArticle

31 Scopus citations

A novel small molecule, LAS-0811, inhibits alcohol-induced apoptosis in VL-17A cells

Kim, T. H., Venugopal, S. K., Zhu, M., Wang, S. S., Lau, D., Lam, K. S., Clemens, D. L. & Zern, M. A., Feb 20 2009, In : Biochemical and Biophysical Research Communications. 379, 4, p. 876-881 6 p.

Research output: Contribution to journalArticle

4 Scopus citations

Autophagy reduces acute ethanol-induced hepatotoxicity and steatosis in mice

Ding, W., Li, M., Chen, X., Ni, H., Lin, C., Gao, W., Lu, B., Stolz, D. B., Clemens, D. L. & Yin, X., Nov 2010, In : Gastroenterology. 139, 5, p. 1740-1752 13 p.

Research output: Contribution to journalArticle

310 Scopus citations

Characterization of human liver thermostable phenol sulfotransferase (SULT1A1) allozymes with 3,3′,5-triiodothyronine as the substrate

Li, X., Clemens, D. L., Cole, J. R. & Anderson, R. J., 2001, In : Journal of Endocrinology. 171, 3, p. 525-532 8 p.

Research output: Contribution to journalArticle

27 Scopus citations

Characterization of recombinant human liver dehydroepiandrosterone sulfotransferase (DHEA ST) with minoxidil as the substrate

Kudlacek, P., Clemens, D., Halgard, C. & Anderson, R., 1996, In : FASEB Journal. 10, 3, p. A456

Research output: Contribution to journalArticle

Characterization of recombinant human liver dehydroepiandrosterone sulfotransferase with minoxidil as the substrate

Kudlacek, P. E., Clemens, D. L., Halgard, C. M. & Anderson, R. J., Jan 24 1997, In : Biochemical Pharmacology. 53, 2, p. 215-221 7 p.

Research output: Contribution to journalArticle

11 Scopus citations

Characterization of recombinant human liver thermolabile phenol sulfotransferase with minoxidil as the substrate

Kudlacek, P. E., Clemens, D. L. & Anderson, R. J., May 16 1995, In : Biochemical and Biophysical Research Communications. 210, 2, p. 363-369 7 p.

Research output: Contribution to journalArticle

13 Scopus citations
1 Scopus citations
16 Scopus citations
9 Scopus citations

Effects of Ethanol Feeding on the Interaction of Rat Hepatocytes with Laminin Peptides

Xu, D., Sorrell, M. F., Clemens, D. L., Casey, C. A. & Tuma, D. J., Oct 1994, In : Alcoholism: Clinical and Experimental Research. 18, 5, p. 1215-1219 5 p.

Research output: Contribution to journalArticle

5 Scopus citations
8 Scopus citations

Establishment of a recombinant hepatic cell line stably expressing alcohol dehydrogenase

Clemens, D. L., Halgard, C. M., Miles, R. R., Sorrell, M. F. & Tuma, D. J., Aug 20 1995, In : Archives of Biochemistry and Biophysics. 321, 2, p. 311-318 8 p.

Research output: Contribution to journalArticle

53 Scopus citations

Ethanol administration impairs pancreatic repair after injury

Schneider, K. J. M., Scheer, M., Suhr, M. & Clemens, D. L., Nov 2012, In : Pancreas. 41, 8, p. 1272-1279 8 p.

Research output: Contribution to journalArticle

9 Scopus citations

Ethanol consumption potentiates viral pancreatitis and may inhibit pancreas regeneration: Preliminary findings

Clemens, D. L. & Jerrells, T. R., 2004, In : Alcohol. 33, 3, p. 183-189 7 p.

Research output: Contribution to journalArticle

31 Scopus citations

Ethanol-induced oxidative stress suppresses generation of peptides for antigen presentation by hepatoma cells

Osna, N. A., White, R. L., Todero, S., Mc Vicker, B. L., Thiele, G. M., Clemens, D. L., Tuma, D. J. & Donohue, T. M., Jan 2007, In : Hepatology. 45, 1, p. 53-61 9 p.

Research output: Contribution to journalArticle

39 Scopus citations
27 Scopus citations

Ethanol metabolism activates cell cycle checkpoint kinase, Chk2

Clemens, D. L., Mahan Schneider, K. J. & Nuss, R. F., Dec 2011, In : Alcohol. 45, 8, p. 785-793 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

Ethanol metabolism alters interferon gamma signaling in recombinant HepG2 cells

Osna, N. A., Clemens, D. L. & Donohue, T. M., Nov 2005, In : Hepatology. 42, 5, p. 1109-1117 9 p.

Research output: Contribution to journalArticle

44 Scopus citations

Ethanol metabolism results in a G2/M cell-cycle arrest in recombinant Hep G2 cells

Clemens, D. L., Calisto, L. E., Sorrell, M. F. & Tuma, D. J., Aug 1 2003, In : Hepatology. 38, 2, p. 385-393 9 p.

Research output: Contribution to journalArticle

24 Scopus citations

Ethanol oxidation mediates impaired hepatic receptor-mediated enocytosis

Clemens, D. L., Casey, C. A., Sorrell, M. F. & Tuma, D. J., 1998, In : Alcoholism: Clinical and Experimental Research. 22, 4, p. 778-779 2 p.

Research output: Contribution to journalArticle

11 Scopus citations

Expression of Aleutian mink disease parvovirus capsid proteins by a recombinant vaccinia virus: Self-assembly of capsid proteins into particles

Clemens, D. L., Wolfinbarger, J. B., Mori, S., Berry, B. D., Hayes, S. F. & Bloom, M. E., 1992, In : Journal of virology. 66, 5, p. 3077-3085 9 p.

Research output: Contribution to journalArticle

Open Access
23 Scopus citations

Free fatty acids enhance the oxidative damage induced by ethanol metabolism in an in vitro model

Hernández, I., Domínguez-Pérez, M., Bucio, L., Souza, V., Miranda, R. U., Clemens, D. L., Gomez-Quiroz, L. E. & Gutiérrez-Ruiz, M. C., Feb 1 2015, In : Food and Chemical Toxicology. 76, p. 109-115 7 p.

Research output: Contribution to journalArticle

14 Scopus citations

GSH protects against oxidative stress and toxicity in VL-17A cells exposed to high glucose

Kumar, S. M., Swaminathan, K., Clemens, D. L. & Dey, A., 2015, In : European Journal of Nutrition. 54, 2, p. 223-234 12 p.

Research output: Contribution to journalArticle

9 Scopus citations

Hepatic mitochondrial dysfunction induced by fatty acids and ethanol

Gyamfi, D., Everitt, H. E., Tewfik, I., Clemens, D. L. & Patel, V. B., Dec 1 2012, In : Free Radical Biology and Medicine. 53, 11, p. 2131-2145 15 p.

Research output: Contribution to journalArticle

18 Scopus citations

Hepatocyte growth factor protects hepatocytes against oxidative injury induced by ethanol metabolism

Valdés-Arzate, A., Luna, A., Bucio, L., Licona, C., Clemens, D. L., Souza, V., Hernandez, E., Kershenobich, D., Gutiérrez-Ruiz, M. C. & Gómez-Quiroz, L. E., Aug 15 2009, In : Free Radical Biology and Medicine. 47, 4, p. 424-430 7 p.

Research output: Contribution to journalArticle

39 Scopus citations

High omega arachidonic acid/docosahexaenoic acid ratio induces mitochondrial dysfunction and altered lipid metabolism in human hepatoma cells

Ghazali, R., Mehta, K. J., Bligh, S. W. A., Tewfik, I., Clemens, D. & Patel, V. B., Mar 27 2020, In : World Journal of Hepatology. 12, 3, p. 84-98 15 p.

Research output: Contribution to journalArticle

Open Access

Human liver thermostable phenol sulfotransferase its PST: CDNA cloning, bacterial expression and characterization

Clemens, D., Cole, J., Kudlacek, P., Halgard, C. & Andersen, R., 1996, In : FASEB Journal. 10, 3, p. A284

Research output: Contribution to journalArticle

3 Scopus citations

Impairment of the asialoglycoprotein receptor by ethanol oxidation

Clemens, D. L., Halgard, C. M., Cole, J. R., Miles, R. M., Sorrell, M. F. & Tuma, D. J., Nov 22 1996, In : Biochemical Pharmacology. 52, 10, p. 1499-1505 7 p.

Research output: Contribution to journalArticle

12 Scopus citations
8 Scopus citations

Inhibition of CYP2E1 leads to decreased malondialdehyde-acetaldehyde adduct formation in VL-17A cells under chronic alcohol exposure

Swaminathan, K., Clemens, D. L. & Dey, A., Mar 14 2013, In : Life Sciences. 92, 6-7, p. 325-336 12 p.

Research output: Contribution to journalArticle

14 Scopus citations
48 Scopus citations

In Vitro Evidence for Chronic Alcohol and High Glucose Mediated Increased Oxidative Stress and Hepatotoxicity

Chandrasekaran, K., Swaminathan, K., Mathan Kumar, S., Clemens, D. L. & Dey, A., Jun 2012, In : Alcoholism: Clinical and Experimental Research. 36, 6, p. 1004-1012 9 p.

Research output: Contribution to journalArticle

11 Scopus citations

Knock down of GCN5 histone acetyltransferase by siRNA decreases ethanol-induced histone acetylation and affects differential expression of genes in human hepatoma cells

Choudhury, M., Pandey, R. S., Clemens, D. L., Davis, J. W., Lim, R. W. & Shukla, S. D., Jun 2011, In : Alcohol. 45, 4, p. 311-324 14 p.

Research output: Contribution to journalArticle

18 Scopus citations
9 Scopus citations

Metabolic basis of ethanol-induced cytotoxicity in recombinant HepG2 cells: Role of nonoxidative metabolism

Wu, H., Cai, P., Clemens, D. L., Jerrells, T. R., Ansari, G. A. S. & Kaphalia, B. S., Oct 15 2006, In : Toxicology and Applied Pharmacology. 216, 2, p. 238-247 10 p.

Research output: Contribution to journalArticle

40 Scopus citations

Mitochondrial morphology and dynamics in hepatocytes from normal and ethanol-fed rats

Das, S., Hajnóczky, N., Antony, A. N., Csordás, G., Gaspers, L. D., Clemens, D. L., Hoek, J. B. & Hajnóczky, G., Jul 2012, In : Pflugers Archiv European Journal of Physiology. 464, 1, p. 101-109 9 p.

Research output: Contribution to journalArticle

29 Scopus citations

Modulation of GSH with exogenous agents leads to changes in glyoxalase 1 enzyme activity in VL-17A cells exposed to chronic alcohol plus high glucose

Kumar, S. M., Swaminathan, K., Clemens, D. L. & Dey, A., Feb 2014, In : Food and Function. 5, 2, p. 345-358 14 p.

Research output: Contribution to journalArticle

2 Scopus citations

Mucin-1 is required for Coxsackie Virus B3-induced inflammation in pancreatitis

Liu, X., Clemens, D. L., Grunkemeyer, J. A., Price, J. D., O’Connell, K., Chapman, N. M., Storz, P., Wen, H., Cox, J. L., Reid, W. L., Hollingsworth, M. A. & Thayer, S., Dec 1 2019, In : Scientific reports. 9, 1, 10656.

Research output: Contribution to journalArticle

Open Access

Multilevel regulation of autophagosome content by ethanol oxidation in HepG2 cells

Thomes, P. G., Ehlers, R. A., Trambly, C. S., Clemens, D. L., Fox, H. S., Tuma, D. J. & Donohue, T. M., Jan 2013, In : Autophagy. 9, 1, p. 63-73 11 p.

Research output: Contribution to journalArticle

47 Scopus citations

Novel antioxidant properties of doxycycline

Clemens, D. L., Duryee, M. J., Sarmiento, C., Chiou, A., McGowan, J. D., Hunter, C. D., Schlichte, S. L., Tian, J., Klassen, L. W., O'Dell, J. R., Thiele, G. M., Mikuls, T. R., Zimmerman, M. C. & Anderson, D. R., 2018, In : International journal of molecular sciences. 19, 12, 4078.

Research output: Contribution to journalArticle

6 Scopus citations
92 Scopus citations

Regulated expression of the feline panleukopenia virus P38 promoter on extrachromosomal FPV/EBV chimeric plasmids

Clemens, D. L. & Carlson, J. O., 1989, In : Journal of virology. 63, 6, p. 2737-2745 9 p.

Research output: Contribution to journalArticle

Open Access
13 Scopus citations

Relationship between acetaldehyde levels and cell survival in ethanol-metabolizing hepatoma cells

Clemens, D. L., Forman, A., Jerrells, T. R., Sorrell, M. F. & Tuma, D. J., 2002, In : Hepatology. 35, 5, p. 1196-1204 9 p.

Research output: Contribution to journalArticle

60 Scopus citations

Retinoid regulation of antiviral innate immunity in hepatocytes

Cho, N. E., Bang, B. R., Gurung, P., Li, M., Clemens, D. L., Underhill, T. M., James, L. P., Chase, J. R. & Saito, T., 2016, In : Hepatology. 63, 6, p. 1783-1795 13 p.

Research output: Contribution to journalArticle

11 Scopus citations

Role of MAPK phosphatase-1 in sustained activation of JNK during ethanol-induced apoptosis in hepatocyte-like VL-17A cells

Venugopal, S. K., Chen, J., Zhang, Y., Clemens, D., Follenzi, A. & Zern, M. A., Nov 2 2007, In : Journal of Biological Chemistry. 282, 44, p. 31900-31908 9 p.

Research output: Contribution to journalArticle

48 Scopus citations