• 913 Citations
  • 18 h-Index
1991 …2020

Research output per year

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Research Output

  • 913 Citations
  • 18 h-Index
  • 67 Article
  • 1 Comment/debate
  • 1 Short survey
2020

Evidence for anti-viral effects of complete freund’s adjuvant in the mouse model of enterovirus infection

Gangaplara, A., Massilamany, C., Lasrado, N., Steffen, D. & Reddy, J., Sep 2020, In : Vaccines. 8, 3, p. 1-9 9 p., 364.

Research output: Contribution to journalArticle

Open Access

Identification of immunogenic epitopes that permit the detection of antigen-specific T cell responses in multiple serotypes of group B coxsackievirus infections

Lasrado, N., Gangaplara, A., Arumugam, R., Massilamany, C., Pokal, S., Zhou, Y., Xiang, S. H., Steffen, D. & Reddy, J., 2020, In : Viruses. 12, 3, 347.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Uterine Torsion Dystocia Complicated by Perosomus Elumbis in an Angus Calf Associated with a Consanguineous Mating

Helms, A. B., Thompson, R. E., Lawton, S., Petersen, J. L., Watson, A., Sula, M. J., Steffen, D. & Whitlock, B. K., 2020, In : Case Reports in Veterinary Medicine. 2020, 6543037.

Research output: Contribution to journalArticle

Open Access

Viral myocarditis involves the generation of autoreactive T cells with multiple antigen specificities that localize in lymphoid and non-lymphoid organs in the mouse model of CVB3 infection

Basavalingappa, R. H., Arumugam, R., Lasrado, N., Yalaka, B., Massilamany, C., Gangaplara, A., Riethoven, J. J., Xiang, S. H., Steffen, D. & Reddy, J., Aug 2020, In : Molecular Immunology. 124, p. 218-228 11 p.

Research output: Contribution to journalArticle

2019

Design and characterization of a consensus hemagglutinin vaccine immunogen against H3 influenza A viruses of swine

Sun, H., Sur, J. H., Sillman, S., Steffen, D. & Vu, H. L. X., Dec 2019, In : Veterinary Microbiology. 239, 108451.

Research output: Contribution to journalArticle

Open Access

Evidence for a de novo, dominant germ-line mutation causative of osteogenesis imperfecta in two Red Angus calves

Petersen, J. L., Tietze, S. M., Burrack, R. M. & Steffen, D. J., Apr 1 2019, In : Mammalian Genome. 30, 3-4, p. 81-87 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

Investigation of congestive heart failure in beef cattle in a feedyard at a moderate altitude in western Nebraska

Moxley, R. A., Smith, D. R., Grotelueschen, D. M., Edwards, T. & Steffen, D. J., Jul 1 2019, In : Journal of Veterinary Diagnostic Investigation. 31, 4, p. 509-522 14 p.

Research output: Contribution to journalArticle

1 Scopus citations
2018

Development of a broadly protective modified-live virus vaccine candidate against porcine reproductive and respiratory syndrome virus

Sun, H., Workman, A., Osorio, F. A., Steffen, D. & Vu, H. L. X., Jan 2 2018, In : Vaccine. 36, 1, p. 66-73 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Epitope Mapping of SERCA2a Identifies an Antigenic Determinant That Induces Mainly Atrial Myocarditis in A/J Mice

Krishnan, B., Massilamany, C., Basavalingappa, R. H., Gangaplara, A., Rajasekaran, R. A., Afzal, M. Z., Khalilzad-Sharghi, V., Zhou, Y., Riethoven, J. J., Nandi, S. S., Mishra, P. K., Sobel, R. A., Strande, J. L., Steffen, D. & Reddy, J., Jan 15 2018, In : Journal of Immunology. 200, 2, p. 523-537 15 p.

Research output: Contribution to journalArticle

2 Scopus citations
2017

Branched chain α-ketoacid dehydrogenase kinase 111-130, a T cell epitope that induces both autoimmune myocarditis and hepatitis in A/J mice

Krishnan, B., Massilamany, C., Basavalingappa, R. H., Gangaplara, A., Kang, G., Li, Q., Uzal, F. A., Strande, J. L., Delhon, G. A., Riethoven, J. J., Steffen, D. & Reddy, J., 2017, In : Immunity Inflammation and Disease. 5, 4, p. 421-434 14 p.

Research output: Contribution to journalArticle

5 Scopus citations

Cross reactivity of immune responses to porcine reproductive and respiratory syndrome virus infection

Correas, I., Osorio, F. A., Steffen, D., Pattnaik, A. K. & Vu, H. L. X., Feb 1 2017, In : Vaccine. 35, 5, p. 782-788 7 p.

Research output: Contribution to journalArticle

19 Scopus citations

Experimental acute infection of alpacas with Bovine viral diarrhea virus 1 subgenotype b alters peripheral blood and GALT leukocyte subsets

Topliff, C. L., Alkheraif, A. A., Kuszynski, C. A., Davis, W. C., Steffen, D. J., Schmitz, J. A., Eskridge, K. M., Charleston, B., Henningson, J. N. & Kelling, C. L., Mar 1 2017, In : Journal of Veterinary Diagnostic Investigation. 29, 2, p. 186-192 7 p.

Research output: Contribution to journalArticle

Relative contribution of porcine reproductive and respiratory syndrome virus open reading frames 2–4 to the induction of protective immunity

Kimpston-Burkgren, K., Correas, I., Osorio, F. A., Steffen, D., Pattnaik, A. K., Fang, Y. & Vu, H. L. X., Aug 3 2017, In : Vaccine. 35, 34, p. 4408-4413 6 p.

Research output: Contribution to journalArticle

2 Scopus citations

Serum blood metabolite response and evaluation of select organ weight, histology, and cardiac morphology of beef heifers exposed to a dual corticotropin-releasing hormone and vasopressin challenge following supplementation of zilpaterol hydrochloride

Buntyn, J. O., Steffen, D., Burdick Sanchez, N. C., Sieren, S. E., Jones, S. J., Erickson, G. E., Carroll, J. A. & Schmidt, T. B., Dec 2017, In : Journal of animal science. 95, 12, p. 5327-5338 12 p.

Research output: Contribution to journalArticle

4 Scopus citations

Zika virus encoding nonglycosylated envelope protein is attenuated and defective in neuroinvasion

Annamalai, A. S., Pattnaik, A., Sahoo, B. R., Muthukrishnan, E., Natarajan, S. K., Steffen, D., Vu, H. L. X., Delhon, G., Osorio, F. A., Petro, T. M., Xiang, S. H. & Pattnaik, A. K., Dec 1 2017, In : Journal of virology. 91, 23, e01348-17.

Research output: Contribution to journalArticle

35 Scopus citations

β1-adrenergic receptor contains multiple IAk and IEk binding epitopes that induce T cell responses with varying degrees of autoimmune myocarditis in A/J mice

Basavalingappa, R. H., Massilamany, C., Krishnan, B., Gangaplara, A., Rajasekaran, R. A., Afzal, M. Z., Riethoven, J. J., Strande, J. L., Steffen, D. & Reddy, J., Nov 20 2017, In : Frontiers in immunology. 8, NOV, 1567.

Research output: Contribution to journalArticle

3 Scopus citations
2016

Identification of an Epitope from Adenine Nucleotide Translocator 1 That Induces Inflammation in Heart in A/J Mice

Basavalingappa, R. H., Massilamany, C., Krishnan, B., Gangaplara, A., Kang, G., Khalilzad-Sharghi, V., Han, Z., Othman, S., Li, Q., Riethoven, J. J., Sobel, R. A., Steffen, D. & Reddy, J., Dec 1 2016, In : American Journal of Pathology. 186, 12, p. 3160-3175 16 p.

Research output: Contribution to journalArticle

6 Scopus citations

Localization of CD8 T cell epitope within cardiac myosin heavy chain-α334-352 that induces autoimmune myocarditis in A/J mice

Massilamany, C., Gangaplara, A., Basavalingappa, R. H., Rajasekaran, R. A., Khalilzad-Sharghi, V., Han, Z., Othman, S., Steffen, D. & Reddy, J., Jan 1 2016, In : International Journal of Cardiology. 202, p. 311-321 11 p.

Research output: Contribution to journalArticle

12 Scopus citations
2015

A synthetic porcine reproductive and respiratory syndrome virus strain confers unprecedented levels of heterologous protection

Vu, H. L. X., Ma, F., Laegreid, W. W., Pattnaik, A. K., Steffen, D., Doster, A. R. & Osorio, F. A., 2015, In : Journal of virology. 89, 23, p. 12070-12083 14 p.

Research output: Contribution to journalArticle

17 Scopus citations

Mutations in the 5' NTR and the non-structural protein 3A of the coxsackievirus B3 selectively attenuate myocarditogenicity

Massilamany, C., Gangaplara, A., Basavalingappa, R. H., Rajasekaran, R. A., Vu, H., Riethoven, J. J., Steffen, D., Pattnaik, A. K. & Reddy, J., Jun 22 2015, In : PloS one. 10, 6, e0131052.

Research output: Contribution to journalArticle

5 Scopus citations
2014

Distribution of lymphoid depletion and viral antigen in alpacas experimentally infected with Bovine viral diarrhea virus 1

Steffen, D. J., Topliff, C. L., Schmitz, J. A., Kammerman, J. R., Henningson, J. N., Eskridge, K. M. & Kelling, C. L., Jan 2014, In : Journal of Veterinary Diagnostic Investigation. 26, 1, p. 35-41 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

Noninvasive assessment of cardiac abnormalities in experimental autoimmune myocarditis by magnetic resonance microscopy imaging in the mouse

Massilamany, C., Khalilzad-Sharghi, V., Gangaplara, A., Steffen, D., Othman, S. F. & Reddy, J., Jun 20 2014, In : Journal of Visualized Experiments. 88, e51654.

Research output: Contribution to journalArticle

6 Scopus citations

SJL mice infected with Acanthamoeba castellanii develop central nervous system autoimmunity through the generation of cross-reactive T cells for myelin antigens

Massilamany, C., Marciano-Cabral, F., Da Rocha-Azevedo, B., Jamerson, M., Gangaplara, A., Steffen, D., Zabad, R., Illes, Z., Sobel, R. A. & Reddy, J., May 30 2014, In : PloS one. 9, 5, e98506.

Research output: Contribution to journalArticle

7 Scopus citations
2013

Copper-zinc superoxide dismutase-deficient mice show increased susceptibility to experimental autoimmune encephalomyelitis induced with myelin oligodendrocyte glycoprotein 35-55

Massilamany, C., Gangaplara, A., Kim, H., Stanford, C., Rathnaiah, G., Steffen, D., Lee, J. & Reddy, J., Mar 15 2013, In : Journal of Neuroimmunology. 256, 1-2, p. 19-27 9 p.

Research output: Contribution to journalArticle

8 Scopus citations
7 Scopus citations

Pathology in practice

Cushing, T. L., Steffen, D. & Duhamel, G. E., Feb 2013, In : Journal of the American Veterinary Medical Association. 242, 3, p. 317-319 3 p.

Research output: Contribution to journalArticle

2 Scopus citations

Potential of urinary metabolites for diagnosing multiple sclerosis

Gebregiworgis, T., Massilamany, C., Gangaplara, A., Thulasingam, S., Kolli, V., Werth, M. T., Dodds, E. D., Steffen, D., Reddy, J. & Powers, R., Apr 19 2013, In : ACS chemical biology. 8, 4, p. 684-690 7 p.

Research output: Contribution to journalArticle

9 Scopus citations

Systemic Distribution of Viral Antigen in Alpacas Persistently Infected With Bovine Pestivirus

Henningson, J. N., Steffen, D. J., Topliff, C. L., Kurth, K. L., Dubielzig, R. R., Brodersen, B. W., Bedenice, D., Eskridge, K. M., Callan, R. J., Reggiardo, C., Rupp, G. P. & Kelling, C. L., 2013, In : Veterinary pathology. 50, 2, p. 308-317 10 p.

Research output: Contribution to journalArticle

6 Scopus citations
2012

Coxsackievirus B3 infection leads to the generation of cardiac myosin heavy chain-α-reactive CD4 T cells in A/J mice

Gangaplara, A., Massilamany, C., Brown, D. M., Delhon, G., Pattnaik, A. K., Chapman, N., Rose, N., Steffen, D. & Reddy, J., Sep 2012, In : Clinical Immunology. 144, 3, p. 237-249 13 p.

Research output: Contribution to journalArticle

38 Scopus citations
2011

Gender differences in CNS autoimmunity induced by mimicry epitope for PLP 139-151 in SJL mice

Massilamany, C., Thulasingam, S., Steffen, D. & Reddy, J., Jan 2011, In : Journal of Neuroimmunology. 230, 1-2, p. 95-104 10 p.

Research output: Contribution to journalArticle

14 Scopus citations

Identification of a second mimicry epitope from Acanthamoeba castellanii that induces CNS autoimmunity by generating cross-reactive T cells for MBP 89-101 in SJL mice

Massilamany, C., Asojo, O. A., Gangaplara, A., Steffen, D. & Reddy, J., Dec 2011, In : International Immunology. 23, 12, p. 729-739 11 p.

Research output: Contribution to journalArticle

9 Scopus citations

Identification of novel mimicry epitopes for cardiac myosin heavy chain-α that induce autoimmune myocarditis in A/J mice

Massilamany, C., Gangaplara, A., Steffen, D. & Reddy, J., 2011, In : Cellular Immunology. 271, 2, p. 438-449 12 p.

Research output: Contribution to journalArticle

42 Scopus citations

TCA cycle inactivation in Staphylococcus aureus alters nitric oxide production in RAW 264.7 cells

Massilamany, C., Gangaplara, A., Gardner, D. J., Musser, J. M., Steffen, D., Somerville, G. A. & Reddy, J., Sep 2011, In : Molecular and cellular biochemistry. 355, 1-2, p. 75-82 8 p.

Research output: Contribution to journalArticle

8 Scopus citations
2010

A deletion mutation in bovine SLC4A2 is associated with osteopetrosis in Red Angus cattle

Meyers, S. N., McDaneld, T. G., Swist, S. L., Marron, B. M., Steffen, D. J., O'Toole, D., O'Connell, J. R., Beever, J. E., Sonstegard, T. S. & Smith, T. P. L., May 27 2010, In : BMC genomics. 11, 1, 337.

Research output: Contribution to journalArticle

51 Scopus citations
28 Scopus citations

Pulmonary adenocarcinoma and endogenous lipid pneumonia in a common genet (Genetta genetta)

Perpiñáln, D., Steffen, D. & Napier, J. E., Dec 2010, In : Journal of Zoo and Wildlife Medicine. 41, 4, p. 710-712 3 p.

Research output: Contribution to journalArticle

3 Scopus citations
2009

A nonsense mutation in cGMP-dependent type II protein kinase (PRKG2) causes dwarfism in American Angus cattle

Koltes, J. E., Mishra, B. P., Kumar, D., Kataria, R. S., Totir, L. R., Fernando, R. L., Cobbold, R., Steffen, D., Coppieters, W., Georges, M. & Reecy, J. M., Nov 17 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 46, p. 19250-19255 6 p.

Research output: Contribution to journalArticle

28 Scopus citations

Effect of the viral protein Npro on virulence of bovine viral diarrhea virus and induction of interferon type I in calves

Henningson, J. N., Topliff, C. L., Gil, L. H. V., Donis, R. O., Steffen, D. J., Charleston, B., Eskridge, K. M. & Kelling, C. L., Sep 2009, In : American journal of veterinary research. 70, 9, p. 1117-1123 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

Prevalence of bovine viral diarrhea virus infections in alpacas in the United States

Topliff, C. L., Smith, D. R., Clowser, S. L., Steffen, D. J., Henningson, J. N., Brodersen, B. W., Bedenice, D., Callan, R. J., Reggiardo, C., Kurth, K. L. & Kelling, C. L., Feb 15 2009, In : Journal of the American Veterinary Medical Association. 234, 4, p. 519-529 11 p.

Research output: Contribution to journalArticle

34 Scopus citations
2007
24 Scopus citations
2006

Defective splicing of Megf7/Lrp4, a regulator of distal limb development, in autosomal recessive mulefoot disease

Johnson, E. B., Steffen, D. J., Lynch, K. W. & Herz, J., Nov 2006, In : Genomics. 88, 5, p. 600-609 10 p.

Research output: Contribution to journalArticle

37 Scopus citations

Diagnostic survey of bovine abortion with special reference to Neospora caninum infection: Importance, repeated abortion and concurrent infection in aborted fetuses in Southern Brazil

Corbellini, L. G., Pescador, C. A., Frantz, F., Wunder, E., Steffen, D., Smith, D. R. & Driemeier, D., Jul 2006, In : Veterinary Journal. 172, 1, p. 114-120 7 p.

Research output: Contribution to journalArticle

28 Scopus citations

Herd-level risk factors for Neospora caninum seroprevalence in dairy farms in southern Brazil

Corbellini, L. G., Smith, D. R., Pescador, C. A., Schmitz, M., Correa, A., Steffen, D. J. & Driemeier, D., May 17 2006, In : Preventive Veterinary Medicine. 74, 2-3, p. 130-141 12 p.

Research output: Contribution to journalArticle

53 Scopus citations
2005
17 Scopus citations
2004

Characterization of the 2002 West Nile virus epidemic in Nebraska and Colorado horses

Salazar, P., Traub-Dargatz, J. L., Morley, P. S., Wilmot, D. D., Steffen, D. J., Cunningham, W. E. & Salman, M. D., Sep 2004, In : Compendium on Continuing Education for the Practicing Veterinarian. 26, 9 SUPPL., p. 3-5 3 p.

Research output: Contribution to journalShort survey

Ileocolitis associated with Anaerobiospirillum in cats

De Cock, H. E. V., Marks, S. L., Stacy, B. A., Zabka, T. S., Burkitt, J., Lu, G., Steffen, D. J. & Duhamel, G. E., Jun 2004, In : Journal of clinical microbiology. 42, 6, p. 2752-2758 7 p.

Research output: Contribution to journalArticle

28 Scopus citations

Outcome of equids with clinical signs of West Nile virus infection and factors associated with death

Salazar, P., Traub-Dargatz, J. L., Morley, P. S., Wilmot, D. D., Steffen, D. J., Cunningham, W. E. & Salman, M. D., Jul 15 2004, In : Journal of the American Veterinary Medical Association. 225, 2, p. 267-274 8 p.

Research output: Contribution to journalArticle

47 Scopus citations
2002

A familial degenerative neuromuscular disease of Gelbvieh cattle

Moisan, P. G., Steffen, D. J., Sanderson, M. W., Nietfeld, J. C., Finley, M. R., Grotelueschen, D. M., Andrews, G. A., Johnson, G., Williamson, L., Rushton, S. D., Hall, D. G. & Harmon, B. G., Mar 2002, In : Journal of Veterinary Diagnostic Investigation. 14, 2, p. 140-149 10 p.

Research output: Contribution to journalArticle

8 Scopus citations

Comparative virulence of isolates of bovine viral diarrhea virus type II in experimentally inoculated six- to nine-month-old calves

Kelling, C. L., Steffen, D. J., Topliff, C. L., Eskridge, K. M., Donis, R. O. & Higuchi, D. S., Oct 1 2002, In : American journal of veterinary research. 63, 10, p. 1379-1384 6 p.

Research output: Contribution to journalArticle

51 Scopus citations