David S Hage

  • 8165 Citations
  • 51 h-Index
1984 …2020

Research output per year

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Research Output

2015

Analysis of drug-protein binding using on-line immunoextraction and high-performance affinity microcolumns: Studies with normal and glycated human serum albumin

Matsuda, R., Jobe, D., Beyersdorf, J. & Hage, D. S., Oct 16 2015, In : Journal of Chromatography A. 1416, p. 112-120 9 p.

Research output: Contribution to journalArticle

13 Scopus citations
11 Scopus citations

Analysis of glipizide binding to normal and glycated human serum albumin by high-performance affinity chromatography

Matsuda, R., Li, Z., Zheng, X. & Hage, D. S., Jul 28 2015, In : Analytical and Bioanalytical Chemistry. 407, 18, p. 5309-5321 13 p., 8688.

Research output: Contribution to journalArticle

13 Scopus citations
16 Scopus citations
22 Scopus citations

Analytical methods for kinetic studies of biological interactions: A review

Zheng, X., Bi, C., Li, Z., Podariu, M. & Hage, D. S., Sep 1 2015, In : Journal of Pharmaceutical and Biomedical Analysis. 113, p. 163-180 18 p.

Research output: Contribution to journalReview article

32 Scopus citations

Chromatographic immunoassays: Strategies and recent developments in the analysis of drugs and biological agents

Matsuda, R., Rodriguez, E., Suresh, D. & Hage, D. S., Nov 2015, In : Bioanalysis. 7, 22, p. 2947-2966 20 p.

Research output: Contribution to journalReview article

7 Scopus citations

Development of enhanced capacity affinity microcolumns by using a hybrid of protein cross-linking/modification and immobilization

Zheng, X., Podariu, M., Bi, C. & Hage, D. S., Jun 26 2015, In : Journal of Chromatography A. 1400, p. 82-90 9 p.

Research output: Contribution to journalArticle

10 Scopus citations

Foreword: Advances in liquid chromatography: New developments in stationary phases and supports for drugs and bioanalytical applications

Hage, D. S., Oct 1 2015, Advances in Liquid Chromatography: New Developments in Stationary Phases. Future Medicine Ltd., p. 2-4 3 p.

Research output: Chapter in Book/Report/Conference proceedingForeword/postscript

Immunoaffinity chromatography

Hage, D. S., Oct 1 2015, Advances in Liquid Chromatography: New Developments in Stationary Phases. Future Medicine Ltd., p. 60-74 15 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Kinetic analysis of drug-protein interactions by affinity chromatography

Bi, C., Beeram, S., Li, Z., Zheng, X. & Hage, D. S., Oct 1 2015, In : Drug Discovery Today: Technologies. 17, p. 16-21 6 p.

Research output: Contribution to journalReview article

9 Scopus citations
2014

Analysis of biomolecular interactions using affinity microcolumns: A review

Zheng, X., Li, Z., Beeram, S., Podariu, M., Matsuda, R., Pfaunmiller, E. L., White, C. J., Carter, N. T. & Hage, D. S., Sep 15 2014, In : Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 968, p. 49-63 15 p.

Research output: Contribution to journalReview article

37 Scopus citations

Analysis of drug interactions with very low density lipoprotein by high-performance affinity chromatography

Sobansky, M. R. & Hage, D. S., Oct 2014, In : Analytical and Bioanalytical Chemistry. 406, 25, p. 6203-6211 9 p.

Research output: Contribution to journalArticle

8 Scopus citations
14 Scopus citations

Clinical applications of capillary electrophoresis based immunoassays

Moser, A. C., Willicott, C. W. & Hage, D. S., Apr 2014, In : ELECTROPHORESIS. 35, 7, p. 937-955 19 p.

Research output: Contribution to journalArticle

21 Scopus citations

Determination of rate constants and equilibrium constants for solution-phase drug-protein interactions by ultrafast affinity extraction

Zheng, X., Li, Z., Podariu, M. I. & Hage, D. S., Jul 1 2014, In : Analytical chemistry. 86, 13, p. 6454-6460 7 p.

Research output: Contribution to journalArticle

35 Scopus citations

Development of microcolumn-based one-site immunometric assays for protein biomarkers

Pfaunmiller, E. L., Anguizola, J. A., Milanuk, M. L., Papastavros, E., Carter, N. T., Matsuda, R., Zheng, X. & Hage, D. S., Oct 31 2014, In : Journal of Chromatography A. 1366, p. 92-100 9 p.

Research output: Contribution to journalArticle

7 Scopus citations

Studies of drug interactions with glycated human serum albumin by high-performance affinity chromatography

Matsuda, R., Kye, S. H., Anguizola, J. & Hage, D. S., Aug 1 2014, In : Reviews in Analytical Chemistry. 33, 2, p. 79-94 16 p.

Research output: Contribution to journalArticle

9 Scopus citations

Studies of metabolite-protein interactions: A review

Matsuda, R., Bi, C., Anguizola, J., Sobansky, M., Rodriguez, E., Vargas Badilla, J., Zheng, X., Hage, B. & Hage, D. S., Sep 1 2014, In : Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 966, p. 48-58 11 p.

Research output: Contribution to journalArticle

23 Scopus citations
2013

Affinity Chromatography

Hage, D. S., Anguizola, J. A., Li, R., Matsuda, R., Papastavros, E., Pfaunmiller, E., Sobansky, M. & Zheng, X., Jan 2013, Liquid Chromatography: Applications. Elsevier Inc., p. 1-23 23 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Scopus citations

Affinity monolith chromatography: A review of principles and recent analytical applications

Pfaunmiller, E. L., Paulemond, M. L., Dupper, C. M. & Hage, D. S., Mar 2013, In : Analytical and Bioanalytical Chemistry. 405, 7, p. 2133-2145 13 p.

Research output: Contribution to journalReview article

82 Scopus citations

Analysis of free fractions for chiral drugs using ultrafast extraction and multi-dimensional high-performance affinity chromatography

Zheng, X., Yoo, M. J. & Hage, D. S., Nov 7 2013, In : Analyst. 138, 21, p. 6262-6265 4 p.

Research output: Contribution to journalArticle

21 Scopus citations

An overview of CE in clinical analysis

Hage, D. S., 2013, Clinical Applications of Capillary Electrophoresis: Methods and Protocols. Humana Press Inc., p. 3-10 8 p. (Methods in Molecular Biology; vol. 919).

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Scopus citations

An overview of CE in clinical analysis

Hage, D. S., 2013, In : Methods in Molecular Biology. 919, p. 3-10 8 p.

Research output: Contribution to journalArticle

Development of affinity microcolumns for drug-protein binding studies in personalized medicine: Interactions of sulfonylurea drugs with in vivo glycated human serum albumin

Anguizola, J., Joseph, K. S., Barnaby, O. S., Matsuda, R., Alvarado, G., Clarke, W., Cerny, R. L. & Hage, D. S., May 7 2013, In : Analytical chemistry. 85, 9, p. 4453-4460 8 p.

Research output: Contribution to journalArticle

44 Scopus citations

LC techniques for bioanalysis: Recent trends and developments

Papastavros, E., Bi, C., Pfaunmiller, E. L. & Hage, D. S., Oct 1 2013, Bioanalysis for Service Users. Future Medicine Ltd., p. 50-64 15 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Review: Glycation of human serum albumin

Anguizola, J., Matsuda, R., Barnaby, O. S., Hoy, K. S., Wa, C., DeBolt, E., Koke, M. & Hage, D. S., Oct 1 2013, In : Clinica Chimica Acta. 425, p. 64-76 13 p.

Research output: Contribution to journalReview article

181 Scopus citations

Use of entrapment and high-performance affinity chromatography to compare the binding of drugs and site-specific probes with normal and glycated human serum albumin

Jackson, A. J., Anguizola, J., Pfaunmiller, E. L. & Hage, D. S., Jul 2013, In : Analytical and Bioanalytical Chemistry. 405, 17, p. 5833-5841 9 p.

Research output: Contribution to journalArticle

28 Scopus citations
2012

Analysis of drug interactions with modified proteins by high-performance affinity chromatography: Binding of glibenclamide to normal and glycated human serum albumin

Matsuda, R., Anguizola, J., Joseph, K. S. & Hage, D. S., Nov 23 2012, In : Journal of Chromatography A. 1265, p. 114-122 9 p.

Research output: Contribution to journalArticle

44 Scopus citations

Biointeraction analysis of immobilized antibodies and related agents by high-performance immunoaffinity chromatography

Pfaunmiller, E., Moser, A. C. & Hage, D. S., Feb 2012, In : Methods. 56, 2, p. 130-135 6 p.

Research output: Contribution to journalArticle

19 Scopus citations
16 Scopus citations

Optimization of human serum albumin monoliths for chiral separations and high-performance affinity chromatography

Pfaunmiller, E. L., Hartmann, M., Dupper, C. M., Soman, S. & Hage, D. S., Dec 21 2012, In : Journal of Chromatography A. 1269, p. 198-207 10 p.

Research output: Contribution to journalArticle

38 Scopus citations

Pharmaceutical and biomedical applications of affinity chromatography: Recent trends and developments

Hage, D. S., Anguizola, J. A., Bi, C., Li, R., Matsuda, R., Papastavros, E., Pfaunmiller, E., Vargas, J. & Zheng, X., Oct 2012, In : Journal of Pharmaceutical and Biomedical Analysis. 69, p. 93-105 13 p.

Research output: Contribution to journalReview article

113 Scopus citations

Principles and applications of immunoaffinity chromatography

Jackson, A. J., Sobansky, M. R. & Hage, D. S., 2012, Antibodies Applications and New Development. Bentham Science Publishers Ltd., p. 156-174 19 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations
2011

Binding of tolbutamide to glycated human serum albumin

Joseph, K. S., Anguizola, J. & Hage, D. S., Jan 25 2011, In : Journal of Pharmaceutical and Biomedical Analysis. 54, 2, p. 426-432 7 p.

Research output: Contribution to journalArticle

64 Scopus citations

Characterization of drug interactions with serum proteins by using high-performance affinity chromatography

Hage, D. S., Anguizola, J., Barnaby, O., Jackson, A., Yoo, M. J., Papastavros, E., Pfaunmiller, E., Sobansky, M. & Tong, Z., May 2011, In : Current Drug Metabolism. 12, 4, p. 313-328 16 p.

Research output: Contribution to journalArticle

55 Scopus citations
26 Scopus citations

Chromatographic analysis of drug interactions in the serum proteome

Hage, D. S., Anguizola, J. A., Jackson, A. J., Matsuda, R., Papastavros, E., Pfaunmiller, E., Tong, Z., Vargas-Badilla, J., Yoo, M. J. & Zheng, X., Jul 2011, In : Analytical Methods. 3, 7, p. 1449-1460 12 p.

Research output: Contribution to journalReview article

32 Scopus citations

Comparison of modification sites formed on human serum albumin at various stages of glycation

Barnaby, O. S., Cerny, R. L., Clarke, W. & Hage, D. S., Jan 30 2011, In : Clinica Chimica Acta. 412, 3-4, p. 277-285 9 p.

Research output: Contribution to journalArticle

101 Scopus citations

Detection of heterogeneous drug-protein binding by frontal analysis and high-performance affinity chromatography

Tong, Z., Joseph, K. S. & Hage, D. S., Dec 9 2011, In : Journal of Chromatography A. 1218, 49, p. 8915-8924 10 p.

Research output: Contribution to journalArticle

18 Scopus citations

Development of a flow-based ultrafast immunoextraction and reverse displacement immunoassay: Analysis of free drug fractions

Schiel, J. E., Tong, Z., Sakulthaew, C. & Hage, D. S., Dec 15 2011, In : Analytical chemistry. 83, 24, p. 9384-9390 7 p.

Research output: Contribution to journalArticle

22 Scopus citations

High-performance affinity chromatography and the analysis of drug interactions with modified proteins: Binding of gliclazide with glycated human serum albumin

Matsuda, R., Anguizola, J., Joseph, K. S. & Hage, D. S., Nov 2011, In : Analytical and Bioanalytical Chemistry. 401, 9, p. 2811-2819 9 p.

Research output: Contribution to journalArticle

48 Scopus citations

High-throughput analysis of drug dissociation from serum proteins using affinity silica monoliths

Yoo, M. J. & Hage, D. S., Aug 2011, In : Journal of Separation Science. 34, 16-17, p. 2255-2263 9 p.

Research output: Contribution to journalArticle

23 Scopus citations

Kinetic studies of drug-protein interactions by using peak profiling and high-performance affinity chromatography: Examination of multi-site interactions of drugs with human serum albumin columns

Tong, Z., Schiel, J. E., Papastavros, E., Ohnmacht, C. M., Smith, Q. R. & Hage, D. S., Apr 15 2011, In : Journal of Chromatography A. 1218, 15, p. 2065-2071 7 p.

Research output: Contribution to journalArticle

39 Scopus citations

Quantitative analysis of glycation patterns in human serum albumin using 16O/18O-labeling and MALDI-TOF MS

Barnaby, O. S., Cerny, R. L., Clarke, W. & Hage, D. S., Aug 17 2011, In : Clinica Chimica Acta. 412, 17-18, p. 1606-1615 10 p.

Research output: Contribution to journalArticle

48 Scopus citations

Research Spotlight: Research in bioanalysis and separations at the University of Nebraska - Lincoln

Hage, D. S., Dodds, E. D., Du, L. & Powers, R., May 2011, In : Bioanalysis. 3, 10, p. 1065-1076 12 p.

Research output: Contribution to journalArticle

48 Scopus citations
2010

Analysis of drug interactions with high-density lipoprotein by high-performance affinity chromatography

Chen, S., Sobansky, M. R. & Hage, D. S., Feb 1 2010, In : Analytical Biochemistry. 397, 1, p. 107-114 8 p.

Research output: Contribution to journalArticle

27 Scopus citations

Analysis of drug-protein binding by ultrafast affinity chromatography using immobilized human serum albumin

Mallik, R., Yoo, M. J., Briscoe, C. J. & Hage, D. S., Apr 2010, In : Journal of Chromatography A. 1217, 17, p. 2796-2803 8 p.

Research output: Contribution to journalArticle

55 Scopus citations