David W Mercer, MD

  • 2668 Citations
  • 29 h-Index
1988 …2014

Research output per year

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Research Output

  • 2668 Citations
  • 29 h-Index
  • 95 Article
  • 6 Review article
  • 5 Chapter

Gastric outlet obstruction

Jawa, R. S. & Mercer, D. W., Jul 1 2013, Common Problems in Acute Care Surgery. Springer New York, p. 227-248 22 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Gastric physiology and acid-peptic disorders

Helmer, K. S. & Mercer, D. W., Jan 1 2006, Modern Surgical Care: Physiologic Foundations and Clinical Applications, Third Edition. CRC Press, Vol. 1. p. 295-368 74 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Gastric Ulcer

Mercer, D. W. & Robinson, E. K., Oct 2004, Surgical Decision Making: Fifth Edition. Elsevier Inc., p. 138-141 4 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Gastroprotective actions of bombesin L-DOPA, and mild irritants: Roles of prostaglandins and sensory neurons

Mercer, D. W., Cross, J. M., Castaneda, A. A. & Gunter, J. A., Jan 1 1998, In : Surgery. 124, 5, p. 864-870 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

Hypertonic saline resuscitation after mesenteric ischemia/reperfusion induces ileal apoptosis

Gonzalez, E. A., Kozar, R. A., Suliburk, J. W., Weisbrodt, N. W., Mercer, D. W. & Moore, F. A., Nov 1 2005, In : Journal of Trauma - Injury, Infection and Critical Care. 59, 5, p. 1092-1098 7 p.

Research output: Contribution to journalArticle

10 Scopus citations

Hypotension during Septic Shock Does Not Correlate with Plasma Levels of Nitric Oxide Metabolites in the Conscious Rat

Klemm, K., Mercer, D. W., Mailman, D. & Moody, F. G., Jan 1 1997, In : Journal of Gastrointestinal Surgery. 1, 4, p. 347-356 10 p.

Research output: Contribution to journalArticle

13 Scopus citations

Image of the month

Liu, T. H., Mehall, J. R. & Mercer, D. W., Jan 1 2001, In : Archives of Surgery. 136, 12, p. 1437-1438 2 p.

Research output: Contribution to journalArticle

9 Scopus citations

Increased expression of alpha-1-antitrypsin, glutathione S-transferase π and vascular endothelial growth factor in human pancreatic adenocarcinoma

Trachte, A. L., Suthers, S. E., Lerner, M. R., Hanas, J. S., Jupe, E. R., Sienko, A. E., Adesina, A. M., Lightfoot, S. A., Brackett, D. J., Postier, R. G., Mercer, D., Barnes, S., Lang, N. & Moore, E., Dec 1 2002, In : American journal of surgery. 184, 6, p. 642-647 6 p.

Research output: Contribution to journalArticle

37 Scopus citations

Inducible nitric oxide synthase mediates gut ischemia/reperfusion-induced ileus only after severe insults

Hassoun, H. T., Weisbrodt, N. W., Mercer, D. W., Kozar, R. A., Moody, F. G. & Moore, F. A., Jan 1 2001, In : Journal of Surgical Research. 97, 2, p. 150-154 5 p.

Research output: Contribution to journalArticle

76 Scopus citations

Induction of NF-κB, IκB-α, and iNOS in rat gastric mucosa during endotoxemia

Helmer, K. S., Chang, L., Cui, Y. & Mercer, D. W., Jan 1 2002, In : Journal of Surgical Research. 104, 1, p. 46-52 7 p.

Research output: Contribution to journalArticle

11 Scopus citations

Inflammatory mechanisms contributing to pancreatic cancer development

Farrow, B., Sugiyama, Y., Chen, A., Uffort, E., Nealon, W., Evers, B. M., Pitt, H. A., Cole, D. J., Mercer, D. W. & O'Leary, J. P., Jun 1 2004, In : Annals of surgery. 239, 6, p. 763-771 9 p.

Research output: Contribution to journalArticle

123 Scopus citations

Isoproterenol-induced gastric mucosal protection from bile acid - Role of endogenous prostaglandins

Mercer, D. W., Merchant, N. B., Ritchie, W. P. & Dempsey, D. T., Oct 1 1995, In : Digestive Diseases and Sciences. 40, 10, p. 2227-2235 9 p.

Research output: Contribution to journalArticle

4 Scopus citations

Ketamine/Xylazine attenuates LPS-induced iNOS expression in various rat tissues

Helmer, K. S., Cui, Y., Dewan, A. & Mercer, D. W., Jun 1 2003, In : Journal of Surgical Research. 112, 1, p. 70-78 9 p.

Research output: Contribution to journalArticle

30 Scopus citations
4 Scopus citations

Ketamine attenuates liver injury attributed to endotoxemia: Role of cyclooxygenase-2

Suliburk, J. W., Helmer, K. S., Gonzalez, E. A., Robinson, E. K. & Mercer, D. W., Aug 1 2005, In : Surgery. 138, 2, p. 134-140 7 p.

Research output: Contribution to journalArticle

46 Scopus citations

Ketamine-induced gastroprotection during endotoxemia: Role of heme-oxygenase-1

Helmer, K. S., Suliburk, J. W. & Mercer, D. W., Sep 1 2006, In : Digestive Diseases and Sciences. 51, 9, p. 1571-1581 11 p.

Research output: Contribution to journalArticle

30 Scopus citations

Ketamine-induced hepatoprotection: The role of heme oxygenase-1

Suliburk, J. W., Ward, J. L., Helmer, K. S., Adams, S. D., Zuckerbraun, B. S. & Mercer, D. W., Jun 1 2009, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 296, 6, p. G1360-G1369

Research output: Contribution to journalArticle

11 Scopus citations

Ketamine inhibits lipopolysacharide (LPS) induced gastric luminal fluid accumulation

Suliburk, J. W., Gonzalez, E. A., Moore-Olufemi, S. D., Weisbrodt, N., Moore, F. A. & Mercer, D. W., Aug 1 2005, In : Journal of Surgical Research. 127, 2, p. 203-207 5 p.

Research output: Contribution to journalArticle

9 Scopus citations

Ketamine suppresses LPS-induced bile reflux and gastric bleeding in the rat

Ward, J. L., Adams, S. D., Delano, B. A., Clarke, C., Radhakrishnan, R. S., Weisbrodt, N. W. & Mercer, D. W., Jan 1 2010, In : Journal of Trauma - Injury, Infection and Critical Care. 68, 1, p. 69-75 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

Laparoscopic cholecystectomy for acute cholecystitis: Technical considerations and outcome

Liu, T. H., Consorti, E. T. & Mercer, D. W., Jan 1 2002, In : Seminars in Laparoscopic Surgery. 9, 1, p. 24-31 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

Laparotomy attenuates lipopolysaccharide-induced gastric bleeding in the rat

Ward, J. L., Delano, B. A., Adams, S. D., Mercer, E. E. & Mercer, D. W., Apr 1 2010, In : Digestive Diseases and Sciences. 55, 4, p. 902-910 9 p.

Research output: Contribution to journalArticle

1 Scopus citations

Leukotriene receptor blockade reduces bile acid-induced superficial gastric mucosal injury

Mercer, D. W., Milner, R., O'Neill, S., Ritchie, W. P. & Dempsey, D. T., Jun 1991, In : Journal of Surgical Research. 50, 6, p. 602-608 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

Lipopolysaccharide-Induced Changes in Rat Gastric H/K-ATPase Expression

Helmer, K. S., West, S. D., Vilela, R., Chang, L., Cui, Y., Kone, B. C. & Mercer, D. W., Apr 1 2004, In : Annals of surgery. 239, 4, p. 501-509 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

Lipopolysaccharide-induced gastrointestinal injury in rats: Role of surface hydrophobicity and bile salts

Dial, E. J., Romero, J. J., Villa, X., Mercer, D. W. & Lichtenberger, L. M., Jan 2002, In : Shock. 17, 1, p. 77-80 4 p.

Research output: Contribution to journalArticle

30 Scopus citations

Lipopolysaccharide-induced gastroprotection is independent of the vagus nerve

Kim, Y. S., Chang, L. K. & Mercer, D. W., Jan 1 2001, In : Digestive Diseases and Sciences. 46, 7, p. 1526-1532 7 p., 342660.

Research output: Contribution to journalArticle

2 Scopus citations

Mediators of bile acid-induced alterations in gastric mucosal blood flow

Ritchie, W. P. & Mercer, D., Jan 1991, In : The American Journal of Surgery. 161, 1, p. 126-130 5 p.

Research output: Contribution to journalArticle

19 Scopus citations

Mesenteric ischemia-reperfusion injury up-regulates certain CC, CXC, and XC chemokines and results in multi-organ injury in a time-dependent manner

Jawa, R. S., Quist, E., Boyer, C. W., Shostrom, V. K. & Mercer, D. W., Jan 1 2013, In : European Cytokine Network. 24, 4, p. 148-156 9 p.

Research output: Contribution to journalArticle

12 Scopus citations
23 Scopus citations

Nitric oxide synthase inhibition negates bombesin-induced gastroprotection

Castañeda, A. A., Kim, Y. S., Chang, L. K., Cui, Y. & Mercer, D. W., Jan 1 2000, In : Surgery. 128, 3, p. 422-428 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

Octreotide acetate attenuates bombesin induced gastroprotection

Mercer, D. W., Chang, L. & Lichtenberger, L. M., Dec 1 1997, In : FASEB Journal. 11, 3, p. A219

Research output: Contribution to journalArticle

Open-chest cardiac massage without major thoracotomy: Metabolic indicators of coronary and cerebral perfusion

Buckman, R. F., Badellino, M. M., Eynon, C. A., Mauro, L. H., Aldridge, S. C., Milner, R. E., Merchant, N. B., Buckman, R. F., Mercer, D., Malaspina, P. J. & Warren, R., Jun 1 1997, In : Resuscitation. 34, 3, p. 247-253 7 p.

Research output: Contribution to journalArticle

24 Scopus citations

Open truncal vagotomy

Mercer, D. W. & Liu, T. H., Jun 2003, In : Operative Techniques in General Surgery. 5, 2, p. 80-85 6 p.

Research output: Contribution to journalArticle

Patient evaluation and management with selective use of magnetic resonance cholangiography and endoscopic retrograde cholangiopancreatography before laparoscopic cholecystectomy

Liu, T. H., Consorti, E. T., Kawashima, A., Tamm, E. P., Kwong, K. L., Gill, B. S., Sellin, J. H., Peden, E. K. & Mercer, D. W., Jul 18 2001, In : Annals of surgery. 234, 1, p. 33-40 8 p.

Research output: Contribution to journalArticle

84 Scopus citations

Postgastrectomy and postvagotomy syndromes

Mercer, D. W. & Goede, M. R., Feb 20 2012, Fischer's Mastery of Surgery: Sixth Edition. Wolters Kluwer Health Adis (ESP), Vol. 1.

Research output: Chapter in Book/Report/Conference proceedingChapter

Post-injury multiple organ failure: The role of the gut

Hassoun, H. T., Kone, B. C., Mercer, D. W., Moody, F. G., Weisbrodt, N. W. & Moore, F. A., Jan 2001, In : Shock. 15, 1, p. 1-10 10 p.

Research output: Contribution to journalArticle

417 Scopus citations

Presidential address: Academic surgery: Can we adapt?

Mercer, D. W., Aug 1 2005, In : Surgery. 138, 2, p. 115-124 10 p.

Research output: Contribution to journalArticle

4 Scopus citations

Protective action of gastrin-17 against alcohol-induced gastric injury in the rat: Role in mucosal defense

Mercer, D. W., Cross, J. M., Smith, G. S. & Miller, T. A., Jan 1 1997, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 273, 2 36-2, p. G365-G373

Research output: Contribution to journalArticle

29 Scopus citations

Protective effect of a 21-aminosteroid against hemorrhage-induced ischemia-reperfusion injury in the rat stomach: role of lipid peroxidation.

Cross, J. M., Smith, G. S., Russell, D. H., Nguyen, P. H., Mercer, D. W., Barreto, J. C. & Miller, T. A., May 1 1995, In : Shock (Augusta, Ga.). 3, 5, p. 385-390 6 p.

Research output: Contribution to journalArticle

2 Scopus citations

Randomized, open-label, comparative study of piperacillin-tazobactam administered by continuous infusion versus intermittent infusion for treatment of hospitalized patients with complicated intra-abdominal infection

Lau, W. K., Mercer, D., Itani, K. M., Nicolau, D. P., Kuti, J. L., Mansfield, D. & Dana, A., Nov 1 2006, In : Antimicrobial Agents and Chemotherapy. 50, 11, p. 3556-3561 6 p.

Research output: Contribution to journalArticle

94 Scopus citations

Rat gastric gelatinase induction during endotoxemia

Robinson, E. K., West, S. D., Garay, A. & Mercer, D. W., Mar 1 2006, In : Digestive Diseases and Sciences. 51, 3, p. 548-559 12 p.

Research output: Contribution to journalArticle

2 Scopus citations

Rat gastric injury after lipopolysaccharide: Role of inducible nitric oxide synthase

Robinson, E. K., Kennison, S. D., Suliburk, J. W. & Mercer, D. W., Sep 1 2005, In : Surgery. 138, 3, p. 523-529 7 p.

Research output: Contribution to journalArticle

9 Scopus citations

Salicylate Enhances Rat Gastric Gelatinase Activity

Robinson, E. K., West, S. D. & Mercer, D. W., Jun 15 2006, In : Journal of Surgical Research. 133, 2, p. 69-75 7 p.

Research output: Contribution to journalArticle

2 Scopus citations

Selective lipoxygenase inhibitor reduces bile acid-induced gastric mucosal injury

Sullivan, T. R., Cordero, J. A., Mercer, D. W., Ritchie, W. P. & Dempsey, D. T., Dec 1992, In : Journal of Surgical Research. 53, 6, p. 568-571 4 p.

Research output: Contribution to journalArticle

2 Scopus citations

Sensory neuron-mediated gastric mucosal protection is blocked by cyclooxygenase inhibition

Mercer, D. W., Ritchie, W. P. & Dempsey, D. T., Jan 1 1994, In : Surgery. 115, 2, p. 156-163 8 p.

Research output: Contribution to journalArticle

12 Scopus citations

Standardized patient care guidelines reduce infectious morbidity in appendectomy patients

Helmer, K. S., Robinson, E. K., Lally, K. P., Vasquez, J. C., Kwong, K. L., Liu, T. H. & Mercer, D. W., Jan 1 2002, In : American journal of surgery. 183, 6, p. 608-613 6 p.

Research output: Contribution to journalArticle

39 Scopus citations

Stimulation of Na+-K+-ATPase by thyrotropin in cultured thyroid follicular cells

Pressley, T. A., Higham, S. C., Joson, L. A. & Mercer, D. W., Jan 1 1995, In : American Journal of Physiology - Cell Physiology. 268, 5 37-5, p. C1252-C1258

Research output: Contribution to journalArticle

12 Scopus citations

Store-operated calcium influx in human gastric cells: Role of endogenous prostaglandins

Kokoska, E. R., Smith, G. S., Miller, T. A., Mercer, D. W., Soybel, D. I. & Matthews, J. B., Jan 1 1998, In : Surgery. 124, 2, p. 429-437 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

The efficacy of magnetic resonance cholangiography for the evaluation of patients with suspected choledocholithiasis before laparoscopic cholecystectomy

Liu, T. H., Consorti, E. T., Kawashima, A., Ernst, R. D., Black, C. T., Greger, P. H., Fischer, R. P. & Mercer, D. W., Dec 1 1999, In : American journal of surgery. 178, 6, p. 480-484 5 p.

Research output: Contribution to journalArticle

67 Scopus citations

The gut in systemic inflammatory response syndrome and sepsis: Enzyme systems fighting multiple organ failure

Suliburk, J., Helmer, K., Moore, F. & Mercer, D., Feb 1 2008, In : European Surgical Research. 40, 2, p. 184-189 6 p.

Research output: Contribution to journalReview article

37 Scopus citations

The impact of diabetes in patients with necrotizing soft tissue infections

Kao, L. S., Knight, M. T., Lally, K. P. & Mercer, D. W., Dec 1 2005, In : Surgical Infections. 6, 4, p. 427-438 12 p.

Research output: Contribution to journalReview article

23 Scopus citations