David W Mercer, MD

  • 2675 Citations
  • 29 h-Index
1988 …2014

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

  • 2675 Citations
  • 29 h-Index
  • 95 Article
  • 7 Review article
  • 5 Chapter
Filter
Article
2014

Anesthesia-related cardiac arrest

Ellis, S. J., Newland, M. C., Simonson, J. A., Peters, K. R., Romberger, D. J., Mercer, D. W., Tinker, J. H., Harter, R. L., Kindscher, J. D., Qiu, F. & Lisco, S. J., 2014, In : Anesthesiology. 120, 4, p. 829-838 10 p.

Research output: Contribution to journalArticle

40 Scopus citations
2013

Farm Machinery Injuries: The 15-Year Experience at an Urban Joint Trauma Center System in a Rural State

Jawa, R. S., Young, D. H., Stothert, J. C., Yetter, D., Dumond, R., Shostrom, V. K., Cemaj, S., Rautiainen, R. H. & Mercer, D. W., Apr 2013, In : Journal of Agromedicine. 18, 2, p. 98-106 9 p.

Research output: Contribution to journalArticle

25 Scopus citations

Mesenteric ischemia-reperfusion injury up-regulates certain CC, CXC, and XC chemokines and results in multi-organ injury in a time-dependent manner

Jawa, R. S., Quist, E., Boyer, C. W., Shostrom, V. K. & Mercer, D. W., 2013, In : European Cytokine Network. 24, 4, p. 148-156 9 p.

Research output: Contribution to journalArticle

12 Scopus citations
2012

A quick primer for setting up and maintaining surgical intensive care in an austere environment: practical tips from volunteers in a mass disaster.

Jawa, R. S., Heir, J. S., Cancelada, D., Young, D. H. & Mercer, D. W., 2012, In : American journal of disaster medicine. 7, 3, p. 223-229 7 p.

Research output: Contribution to journalArticle

2 Scopus citations

Clostridium difficile-associated infection: A disease of varying severity

Jawa, R. S. & Mercer, D. W., Dec 2012, In : American journal of surgery. 204, 6, p. 836-842 7 p.

Research output: Contribution to journalArticle

16 Scopus citations

Data driven linear algebraic methods for analysis of molecular pathways: Application to disease progression in shock/trauma

McGuire, M. F., Sriram Iyengar, M. & Mercer, D. W., Apr 2012, In : Journal of Biomedical Informatics. 45, 2, p. 372-387 16 p.

Research output: Contribution to journalArticle

3 Scopus citations

Two hospitals with 1 trauma system: A joint approach to the care of the injured patient

Jawa, R. S., Young, D. H., Wagner, M., Yetter, D., Shostrom, V., Cemaj, S., Nelson, L., Ramey, R., Sorensen, M., Schwedhelm, M., Mercer, D. W. & Stothert Jr, J. C., Apr 2012, In : American journal of surgery. 203, 4, p. 454-460 7 p.

Research output: Contribution to journalArticle

2011

Effects of ketamine on endotoxin and traumatic brain injury induced cytokine production in the rat

Ward, J. L., Harting, M. T., Cox, C. S. & Mercer, D. W., Jun 2011, In : Journal of Trauma - Injury, Infection and Critical Care. 70, 6, p. 1471-1479 9 p.

Research output: Contribution to journalArticle

30 Scopus citations
23 Scopus citations
2010

Ketamine suppresses LPS-induced bile reflux and gastric bleeding in the rat

Ward, J. L., Adams, S. D., Delano, B. A., Clarke, C., Radhakrishnan, R. S., Weisbrodt, N. W. & Mercer, D. W., Jan 2010, In : Journal of Trauma - Injury, Infection and Critical Care. 68, 1, p. 69-75 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

Laparotomy attenuates lipopolysaccharide-induced gastric bleeding in the rat

Ward, J. L., Delano, B. A., Adams, S. D., Mercer, E. E. & Mercer, D. W., Apr 2010, In : Digestive Diseases and Sciences. 55, 4, p. 902-910 9 p.

Research output: Contribution to journalArticle

1 Scopus citations
2009

Early Cytokine Production Risk Stratifies Trauma Patients for Multiple Organ Failure

Jastrow, K. M., Gonzalez, E. A., McGuire, M. F., Suliburk, J. W., Kozar, R. A., Iyengar, S., Motschall, D. A., McKinley, B. A., Moore, F. A. & Mercer, D. W., Sep 2009, In : Journal of the American College of Surgeons. 209, 3, p. 320-331 12 p.

Research output: Contribution to journalArticle

76 Scopus citations

Fasting exacerbates and feeding diminishes LPS-induced liver injury in the rat

Adams, S. D., Delano, B. A., Helmer, K. S. & Mercer, D. W., Apr 2009, In : Digestive Diseases and Sciences. 54, 4, p. 767-773 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

Ketamine-induced hepatoprotection: The role of heme oxygenase-1

Suliburk, J. W., Ward, J. L., Helmer, K. S., Adams, S. D., Zuckerbraun, B. S. & Mercer, D. W., Jun 2009, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 296, 6, p. G1360-G1369

Research output: Contribution to journalArticle

11 Scopus citations

α-Melanocyte stimulating hormone in critically injured trauma patients

Todd, S. R., Kao, L. S., Catania, A., Mercer, D. W., Adams, S. D. & Moore, F. A., Feb 2009, In : Journal of Trauma - Injury, Infection and Critical Care. 66, 2, p. 465-469 5 p.

Research output: Contribution to journalArticle

6 Scopus citations
2008

Acute, regional inflammatory response after traumatic brain injury: Implications for cellular therapy

Harting, M. T., Jimenez, F., Adams, S. D., Mercer, D. W. & Cox, C. S., Nov 2008, In : Surgery. 144, 5, p. 803-813 11 p.

Research output: Contribution to journalArticle

88 Scopus citations

A report on associations among gastric pH, bleeding, duodenogastric reflux, and outcomes after trauma

Dial, E., Lopez-Storey, M., Adams, S., Lichtenberger, L., Gonzalez, E., McKinley, B., Moore, F. & Mercer, D., Jan 2008, In : Journal of Trauma - Injury, Infection and Critical Care. 64, 1, p. 105-110 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

Cyclooxygenase-1 suppresses lipopolysaccharide-induced changes in rat gastric inducible nitric oxide synthase

West, S. D., Suliburk, J. W., Helmer, K. S. & Mercer, D. W., Feb 2008, In : Critical care medicine. 36, 2, p. 572-579 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

Differential effects of luminal arginine and glutamine on metalloproteinase production in the postischemic gut

Robinson, E. K., Kelly, D. P., Mercer, D. W. & Kozar, R. A., Jul 2008, In : Journal of Parenteral and Enteral Nutrition. 32, 4, p. 433-438 6 p.

Research output: Contribution to journalArticle

11 Scopus citations

Effects of anesthesia on lipopolysaccharide-induced changes in serum cytokines

Adams, S. D., Radhakrishnan, R. S., Helmer, K. S. & Mercer, D. W., Jul 2008, In : Journal of Trauma - Injury, Infection and Critical Care. 65, 1, p. 170-174 5 p.

Research output: Contribution to journalArticle

16 Scopus citations

Effects of poloxamer 188 on human PMN cells

Harting, M. T., Jimenez, F., Kozar, R. A., Moore, F. A., Mercer, D. W., Hunter, R. L., Cox, C. S. & Gonzalez, E. A., Aug 2008, In : Surgery. 144, 2, p. 198-203 6 p.

Research output: Contribution to journalArticle

13 Scopus citations

Gastric alkalinization after major trauma

Cocanour, C. S., Dial, E. D., Lichtenberger, L. M., Gonzalez, E. A., Kozar, R. A., Moore, F. A. & Mercer, D. W., Mar 2008, In : Journal of Trauma - Injury, Infection and Critical Care. 64, 3, p. 681-687 7 p.

Research output: Contribution to journalArticle

4 Scopus citations
2007
4 Scopus citations
2006

Conventional dose hypertonic saline provides optimal gut protection and limits remote organ injury after gut ischemia reperfusion

Gonzalez, E. A., Kozar, R. A., Suliburk, J. W., Weisbrodt, N. W., Mercer, D. W. & Moore, F. A., Jul 2006, In : Journal of Trauma - Injury, Infection and Critical Care. 61, 1, p. 66-73 8 p.

Research output: Contribution to journalArticle

29 Scopus citations

Effect of NOS inhibition on rat gastric matrix metalloproteinase production during endotoxemia

Robinson, E. K., Seaworth, C. M., Suliburk, J. W., Adams, S. D., Kao, L. S. & Mercer, D. W., May 2006, In : Shock. 25, 5, p. 507-514 8 p.

Research output: Contribution to journalArticle

10 Scopus citations

Effects of lipopolysaccharide on gastric stasis: Role of cyclooxygenase

West, S. D., Suliburk, J. W., Smith, G. S. & Mercer, D. W., Apr 2006, In : Digestive Diseases and Sciences. 51, 4, p. 754-765 12 p.

Research output: Contribution to journalArticle

6 Scopus citations

Ketamine-induced gastroprotection during endotoxemia: Role of heme-oxygenase-1

Helmer, K. S., Suliburk, J. W. & Mercer, D. W., Sep 2006, In : Digestive Diseases and Sciences. 51, 9, p. 1571-1581 11 p.

Research output: Contribution to journalArticle

30 Scopus citations

Randomized, open-label, comparative study of piperacillin-tazobactam administered by continuous infusion versus intermittent infusion for treatment of hospitalized patients with complicated intra-abdominal infection

Lau, W. K., Mercer, D., Itani, K. M., Nicolau, D. P., Kuti, J. L., Mansfield, D. & Dana, A., Nov 2006, In : Antimicrobial Agents and Chemotherapy. 50, 11, p. 3556-3561 6 p.

Research output: Contribution to journalArticle

96 Scopus citations

Rat gastric gelatinase induction during endotoxemia

Robinson, E. K., West, S. D., Garay, A. & Mercer, D. W., Mar 2006, In : Digestive Diseases and Sciences. 51, 3, p. 548-559 12 p.

Research output: Contribution to journalArticle

2 Scopus citations

Salicylate Enhances Rat Gastric Gelatinase Activity

Robinson, E. K., West, S. D. & Mercer, D. W., Jun 15 2006, In : Journal of Surgical Research. 133, 2, p. 69-75 7 p.

Research output: Contribution to journalArticle

2 Scopus citations
2005

Differential effects of anesthetics on endotoxin-induced liver injury

Suliburk, J. W., Gonzalez, E. A., Kennison, S. D., Helmer, K. S., Mercer, D. W., Meyer, A. A., Bulger, E. M. & Ogura, H., Apr 2005, In : Journal of Trauma - Injury, Infection and Critical Care. 58, 4, p. 711-717 7 p.

Research output: Contribution to journalArticle

27 Scopus citations

Hypertonic saline resuscitation after mesenteric ischemia/reperfusion induces ileal apoptosis

Gonzalez, E. A., Kozar, R. A., Suliburk, J. W., Weisbrodt, N. W., Mercer, D. W. & Moore, F. A., Nov 2005, In : Journal of Trauma - Injury, Infection and Critical Care. 59, 5, p. 1092-1098 7 p.

Research output: Contribution to journalArticle

10 Scopus citations

Ketamine attenuates liver injury attributed to endotoxemia: Role of cyclooxygenase-2

Suliburk, J. W., Helmer, K. S., Gonzalez, E. A., Robinson, E. K. & Mercer, D. W., Aug 2005, In : Surgery. 138, 2, p. 134-140 7 p.

Research output: Contribution to journalArticle

46 Scopus citations

Ketamine inhibits lipopolysacharide (LPS) induced gastric luminal fluid accumulation

Suliburk, J. W., Gonzalez, E. A., Moore-Olufemi, S. D., Weisbrodt, N., Moore, F. A. & Mercer, D. W., Aug 2005, In : Journal of Surgical Research. 127, 2, p. 203-207 5 p.

Research output: Contribution to journalArticle

9 Scopus citations

Presidential address: Academic surgery: Can we adapt?

Mercer, D. W., Aug 2005, In : Surgery. 138, 2, p. 115-124 10 p.

Research output: Contribution to journalArticle

4 Scopus citations

Rat gastric injury after lipopolysaccharide: Role of inducible nitric oxide synthase

Robinson, E. K., Kennison, S. D., Suliburk, J. W. & Mercer, D. W., Sep 2005, In : Surgery. 138, 3, p. 523-529 7 p.

Research output: Contribution to journalArticle

9 Scopus citations

Time-dependent aggravation or attenuation of lipopolysaccharide-induced gastric injury by nitric oxide synthase inhibition

Suliburk, J. W., Helmer, K. S., Kennison, S. D., Mercer, D. W. & Robinson, E. K., Dec 2005, In : Journal of Surgical Research. 129, 2, p. 265-271 7 p.

Research output: Contribution to journalArticle

10 Scopus citations
2004

Inflammatory mechanisms contributing to pancreatic cancer development

Farrow, B., Sugiyama, Y., Chen, A., Uffort, E., Nealon, W., Evers, B. M., Pitt, H. A., Cole, D. J., Mercer, D. W. & O'Leary, J. P., Jun 2004, In : Annals of surgery. 239, 6, p. 763-771 9 p.

Research output: Contribution to journalArticle

124 Scopus citations

Lipopolysaccharide-Induced Changes in Rat Gastric H/K-ATPase Expression

Helmer, K. S., West, S. D., Vilela, R., Chang, L., Cui, Y., Kone, B. C. & Mercer, D. W., Apr 2004, In : Annals of surgery. 239, 4, p. 501-509 9 p.

Research output: Contribution to journalArticle

14 Scopus citations
2003

Acute pancreatitis in intensive care unit patients: Value of clinical and radiologic prognosticators at predicting clinical course and outcome

Liu, T. H., Kwong, K. L., Tamm, E. P., Gill, B. S., Brown, S. D. & Mercer, D. W., Apr 1 2003, In : Critical care medicine. 31, 4, p. 1026-1030 5 p.

Research output: Contribution to journalArticle

26 Scopus citations

Cholecystokinin secretagogue-induced gastroprotection: Role of nitric oxide and blood flow

West, S. D., Helmer, K. S., Chang, L. K., Cui, Y., Greeley, G. H. & Mercer, D. W., Mar 1 2003, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 284, 3 47-3, p. G399-G410

Research output: Contribution to journalArticle

30 Scopus citations

Diverticulitis in the younger patient

West, S. D., Robinson, E. K., Delu, A. N., Ligon, R. E., Kao, L. S. & Mercer, D. W., Dec 2003, In : American journal of surgery. 186, 6, p. 743-746 4 p.

Research output: Contribution to journalArticle

43 Scopus citations

Effects of ketamine/xylazine on expression of tumor necrosis factor-alpha, inducible nitric oxide synthase, and cyclo-oxygenase-2 in rat gastric mucosa during endotoxemia.

Helmer, K. S., Cui, Y., Chang, L., Dewan, A. & Mercer, D. W., Jul 2003, In : Shock (Augusta, Ga.). 20, 1, p. 63-69 7 p.

Research output: Contribution to journalArticle

40 Scopus citations

Ketamine/Xylazine attenuates LPS-induced iNOS expression in various rat tissues

Helmer, K. S., Cui, Y., Dewan, A. & Mercer, D. W., Jun 1 2003, In : Journal of Surgical Research. 112, 1, p. 70-78 9 p.

Research output: Contribution to journalArticle

30 Scopus citations

Open truncal vagotomy

Mercer, D. W. & Liu, T. H., Jun 2003, In : Operative Techniques in General Surgery. 5, 2, p. 80-85 6 p.

Research output: Contribution to journalArticle

2002

Does upregulation of inducible nitric oxide synthase play a role in hepatic injury?

Liu, T. H., Robinson, E. K., Helmer, K. S., West, S. D., Castaneda, A. A., Chang, L. & Mercer, D. W., Dec 2002, In : Shock. 18, 6, p. 549-554 6 p.

Research output: Contribution to journalArticle

28 Scopus citations

Gastric nitric oxide synthase expression during endotoxemia: Implications in mucosal defense in rats

Helmer, K. S., West, S. D., Shipley, G. L., Chang, L., Cui, Y., Mailman, D. & Mercer, D. W., 2002, In : Gastroenterology. 123, 1, p. 173-186 14 p.

Research output: Contribution to journalArticle

39 Scopus citations

Increased expression of alpha-1-antitrypsin, glutathione S-transferase π and vascular endothelial growth factor in human pancreatic adenocarcinoma

Trachte, A. L., Suthers, S. E., Lerner, M. R., Hanas, J. S., Jupe, E. R., Sienko, A. E., Adesina, A. M., Lightfoot, S. A., Brackett, D. J., Postier, R. G., Mercer, D., Barnes, S., Lang, N. & Moore, E., Dec 1 2002, In : American journal of surgery. 184, 6, p. 642-647 6 p.

Research output: Contribution to journalArticle

37 Scopus citations

Induction of NF-κB, IκB-α, and iNOS in rat gastric mucosa during endotoxemia

Helmer, K. S., Chang, L., Cui, Y. & Mercer, D. W., 2002, In : Journal of Surgical Research. 104, 1, p. 46-52 7 p.

Research output: Contribution to journalArticle

11 Scopus citations

Laparoscopic cholecystectomy for acute cholecystitis: Technical considerations and outcome

Liu, T. H., Consorti, E. T. & Mercer, D. W., 2002, In : Seminars in Laparoscopic Surgery. 9, 1, p. 24-31 8 p.

Research output: Contribution to journalArticle

6 Scopus citations