David W Mercer, MD

  • 2668 Citations
  • 29 h-Index
1988 …2014

Research output per year

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Research Output

  • 2668 Citations
  • 29 h-Index
  • 95 Article
  • 6 Review article
  • 5 Chapter
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Article

Acute, regional inflammatory response after traumatic brain injury: Implications for cellular therapy

Harting, M. T., Jimenez, F., Adams, S. D., Mercer, D. W. & Cox, C. S., Nov 1 2008, In : Surgery. 144, 5, p. 803-813 11 p.

Research output: Contribution to journalArticle

88 Scopus citations

Acute pancreatitis in intensive care unit patients: Value of clinical and radiologic prognosticators at predicting clinical course and outcome

Liu, T. H., Kwong, K. L., Tamm, E. P., Gill, B. S., Brown, S. D. & Mercer, D. W., Apr 1 2003, In : Critical care medicine. 31, 4, p. 1026-1030 5 p.

Research output: Contribution to journalArticle

26 Scopus citations

Adaptive cytoprotection of gastric surface epithelial cells against injury by physiologic concentrations of bile acid

Dempsey, D. T., Mercer, D. W., Deb, B., Sauter, A. & Ritchie, W. P., Jan 1 1990, In : Surgery. 108, 2, p. 348-355 8 p.

Research output: Contribution to journalArticle

13 Scopus citations

Anatomic Considerations in Penetrating Gluteal Wounds

Mercer, D. W., Buckman, R. F., Sood, R., Kerr, T. M. & Gelman, J., Apr 1992, In : Archives of Surgery. 127, 4, p. 407-410 4 p.

Research output: Contribution to journalArticle

11 Scopus citations

Anesthesia-related cardiac arrest

Ellis, S. J., Newland, M. C., Simonson, J. A., Peters, K. R., Romberger, D. J., Mercer, D. W., Tinker, J. H., Harter, R. L., Kindscher, J. D., Qiu, F. & Lisco, S. J., Jan 1 2014, In : Anesthesiology. 120, 4, p. 829-838 10 p.

Research output: Contribution to journalArticle

40 Scopus citations

A quick primer for setting up and maintaining surgical intensive care in an austere environment: practical tips from volunteers in a mass disaster.

Jawa, R. S., Heir, J. S., Cancelada, D., Young, D. H. & Mercer, D. W., Jan 1 2012, In : American journal of disaster medicine. 7, 3, p. 223-229 7 p.

Research output: Contribution to journalArticle

2 Scopus citations

A report on associations among gastric pH, bleeding, duodenogastric reflux, and outcomes after trauma

Dial, E., Lopez-Storey, M., Adams, S., Lichtenberger, L., Gonzalez, E., McKinley, B., Moore, F. & Mercer, D., Jan 1 2008, In : Journal of Trauma - Injury, Infection and Critical Care. 64, 1, p. 105-110 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

Bombesin maintains enterocyte phenotype in fasted rats

Hodin, R. A., Meng, S., Shei, A., Bass, B., Mercer, D. & Rudnicki, M., Jan 1 1994, In : Surgery. 116, 2, p. 426-431 6 p.

Research output: Contribution to journalArticle

7 Scopus citations

Bombesin prevents gastric injury in the rat: Role of gastrin

Mercer, D. W., Cross, J. M., Chang, L. & Lichtenberger, L. M., Apr 29 1998, In : Digestive Diseases and Sciences. 43, 4, p. 826-833 8 p.

Research output: Contribution to journalArticle

20 Scopus citations

Butyrate-induced differentiation of Caco-2 cells is associated with apoptosis and early induction of p21(Waf1/Cip1) and p27(Kip1)

Litvak, D. A., Evers, B. M., Hwang, K. O., Hellmich, M. R., Ko, T. C., Townsend, J., Mercer, D. W., Hodin, R. A., Postier, R. G. & Soybel, D. I., Jan 1 1998, In : Surgery. 124, 2, p. 161-170 10 p.

Research output: Contribution to journalArticle

102 Scopus citations

Capsaicin-induced gastric mucosal hyperemia and protection: The role of calcitonin gene-related peptide

Merchant, N. B., Dempsey, D. T., Grabowski, M. W., Rizzo, M., Ritchie, W. P., Bass, B., Mercer, D., Kellum, J. M. & Carvajal, S., Jan 1 1994, In : Surgery. 116, 2, p. 419-425 7 p.

Research output: Contribution to journalArticle

20 Scopus citations

Cholecystokinin-induced protection against gastric injury is independent of endogenous somatostatin

Mercer, D. W., Klemm, K., Cross, J. M., Smith, G. S., Cashman, M. & Miller, T. A., Oct 1 1996, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 271, 4 34-4, p. G692-G700

Research output: Contribution to journalArticle

28 Scopus citations

Cholecystokinin is a potent protective agent against alcohol-induced gastric injury in the rat - Role of endogenous prostaglandins

Mercer, D. W., Cross, J. M., Barreto, J. C., Strobel, N. H. P., Russell, D. H. & Miller, T. A., Mar 1 1995, In : Digestive Diseases and Sciences. 40, 3, p. 651-660 10 p.

Research output: Contribution to journalArticle

24 Scopus citations

Cholecystokinin secretagogue-induced gastroprotection: Role of nitric oxide and blood flow

West, S. D., Helmer, K. S., Chang, L. K., Cui, Y., Greeley, G. H. & Mercer, D. W., Mar 1 2003, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 284, 3 47-3, p. G399-G410

Research output: Contribution to journalArticle

30 Scopus citations

Clostridium difficile-associated infection: A disease of varying severity

Jawa, R. S. & Mercer, D. W., Dec 1 2012, In : American journal of surgery. 204, 6, p. 836-842 7 p.

Research output: Contribution to journalArticle

16 Scopus citations

Conventional dose hypertonic saline provides optimal gut protection and limits remote organ injury after gut ischemia reperfusion

Gonzalez, E. A., Kozar, R. A., Suliburk, J. W., Weisbrodt, N. W., Mercer, D. W. & Moore, F. A., Jul 1 2006, In : Journal of Trauma - Injury, Infection and Critical Care. 61, 1, p. 66-73 8 p.

Research output: Contribution to journalArticle

29 Scopus citations

Cyclooxygenase-1 suppresses lipopolysaccharide-induced changes in rat gastric inducible nitric oxide synthase

West, S. D., Suliburk, J. W., Helmer, K. S. & Mercer, D. W., Feb 2008, In : Critical care medicine. 36, 2, p. 572-579 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

Cyclooxygenase inhibition attenuates cholecystokinin-induced gastroprotection

Mercer, D. W., Smith, G. S. & Miller, T. A., Apr 18 1998, In : Digestive Diseases and Sciences. 43, 3, p. 468-475 8 p.

Research output: Contribution to journalArticle

10 Scopus citations

Data driven linear algebraic methods for analysis of molecular pathways: Application to disease progression in shock/trauma

McGuire, M. F., Sriram Iyengar, M. & Mercer, D. W., Apr 1 2012, In : Journal of Biomedical Informatics. 45, 2, p. 372-387 16 p.

Research output: Contribution to journalArticle

3 Scopus citations

Differential effects of anesthetics on endotoxin-induced liver injury

Suliburk, J. W., Gonzalez, E. A., Kennison, S. D., Helmer, K. S., Mercer, D. W., Meyer, A. A., Bulger, E. M. & Ogura, H., Apr 1 2005, In : Journal of Trauma - Injury, Infection and Critical Care. 58, 4, p. 711-717 7 p.

Research output: Contribution to journalArticle

27 Scopus citations

Differential effects of luminal arginine and glutamine on metalloproteinase production in the postischemic gut

Robinson, E. K., Kelly, D. P., Mercer, D. W. & Kozar, R. A., Jul 1 2008, In : Journal of Parenteral and Enteral Nutrition. 32, 4, p. 433-438 6 p.

Research output: Contribution to journalArticle

11 Scopus citations

Diverticulitis in the younger patient

West, S. D., Robinson, E. K., Delu, A. N., Ligon, R. E., Kao, L. S. & Mercer, D. W., Dec 2003, In : American journal of surgery. 186, 6, p. 743-746 4 p.

Research output: Contribution to journalArticle

43 Scopus citations

Does upregulation of inducible nitric oxide synthase (iNOS) render the stomach more susceptible to damage?

Castañeda, A. A., Denning, J. W., Chang, L. & Mercer, D. W., Jun 15 1999, In : Journal of Surgical Research. 84, 2, p. 174-179 6 p.

Research output: Contribution to journalArticle

25 Scopus citations

Does upregulation of inducible nitric oxide synthase play a role in hepatic injury?

Liu, T. H., Robinson, E. K., Helmer, K. S., West, S. D., Castaneda, A. A., Chang, L. & Mercer, D. W., Dec 2002, In : Shock. 18, 6, p. 549-554 6 p.

Research output: Contribution to journalArticle

28 Scopus citations

Do leukotrienes mediate bile acid-induced gastric mucosal injury?

Mercer, D. W., Ritchie, W. P. & Dempsey, D. T., Sep 30 1992, In : American Surgeon. 58, 9, p. 567-572 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Do sensory neurons mediate adaptive cytoprotection of gastric mucosa against bile acid injury?

Mercer, D. W., Ritchie, W. P. & Dempsey, D. T., Jan 1992, In : The American Journal of Surgery. 163, 1, p. 12-18 7 p.

Research output: Contribution to journalArticle

15 Scopus citations

Early Cytokine Production Risk Stratifies Trauma Patients for Multiple Organ Failure

Jastrow, K. M., Gonzalez, E. A., McGuire, M. F., Suliburk, J. W., Kozar, R. A., Iyengar, S., Motschall, D. A., McKinley, B. A., Moore, F. A. & Mercer, D. W., Sep 1 2009, In : Journal of the American College of Surgeons. 209, 3, p. 320-331 12 p.

Research output: Contribution to journalArticle

75 Scopus citations

Effect of NOS inhibition on rat gastric matrix metalloproteinase production during endotoxemia

Robinson, E. K., Seaworth, C. M., Suliburk, J. W., Adams, S. D., Kao, L. S. & Mercer, D. W., May 1 2006, In : Shock. 25, 5, p. 507-514 8 p.

Research output: Contribution to journalArticle

10 Scopus citations

Effects of anesthesia on lipopolysaccharide-induced changes in serum cytokines

Adams, S. D., Radhakrishnan, R. S., Helmer, K. S. & Mercer, D. W., Jul 1 2008, In : Journal of Trauma - Injury, Infection and Critical Care. 65, 1, p. 170-174 5 p.

Research output: Contribution to journalArticle

16 Scopus citations

Effects of Cholecystokinin on Gastric Injury and Gastric Mucosal Blood Flow

Cross, J. M., Chang, L. & Mercer, D. W., Jan 1 1998, In : Journal of Gastrointestinal Surgery. 2, 2, p. 198-206 9 p.

Research output: Contribution to journalArticle

3 Scopus citations

Effects of Dopamine and Alpha-2 Adrenoreceptor Blockade on L-Dopa and Cholecystokinin-Induced Gastroprotection

Cross, J. M., Mercer, D. W., Gunter, J. & Miller, T. A., Jan 1 1997, In : Journal of Gastrointestinal Surgery. 1, 3, p. 257-265 9 p.

Research output: Contribution to journalArticle

2 Scopus citations

Effects of endotoxin on gastric injury from luminal irritants in rats: Potential roles of nitric oxide

Mercer, D. W., Castaneda, A. A., Denning, J. W., Chang, L. & Russell, D. H., Sep 1998, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 275, 3 38-3, p. G449-G459

Research output: Contribution to journalArticle

31 Scopus citations

Effects of endotoxin on regulation of intestinal smooth muscle nitric oxide synthase and intestinal transit

Cullen, J. J., Mercer, D., Hinkhouse, M., Ephgrave, K. S. & Conklin, J. L., Jan 1 1999, In : Surgery. 125, 3, p. 339-344 6 p.

Research output: Contribution to journalArticle

39 Scopus citations

Effects of intestinal ischemia/reperfusion injury on gastric acid secretion

Castañeda, A., Vilela, R., Chang, L. & Mercer, D. W., May 1 2000, In : Journal of Surgical Research. 90, 1, p. 88-93 6 p.

Research output: Contribution to journalArticle

6 Scopus citations

Effects of ketamine/xylazine on expression of tumor necrosis factor-alpha, inducible nitric oxide synthase, and cyclo-oxygenase-2 in rat gastric mucosa during endotoxemia.

Helmer, K. S., Cui, Y., Chang, L., Dewan, A. & Mercer, D. W., Jul 2003, In : Shock (Augusta, Ga.). 20, 1, p. 63-69 7 p.

Research output: Contribution to journalArticle

40 Scopus citations

Effects of ketamine on endotoxin and traumatic brain injury induced cytokine production in the rat

Ward, J. L., Harting, M. T., Cox, C. S. & Mercer, D. W., Jun 1 2011, In : Journal of Trauma - Injury, Infection and Critical Care. 70, 6, p. 1471-1479 9 p.

Research output: Contribution to journalArticle

30 Scopus citations

Effects of lipopolysaccharide on gastric stasis: Role of cyclooxygenase

West, S. D., Suliburk, J. W., Smith, G. S. & Mercer, D. W., Apr 1 2006, In : Digestive Diseases and Sciences. 51, 4, p. 754-765 12 p.

Research output: Contribution to journalArticle

6 Scopus citations

Effects of lipopolysaccharide on intestinal injury: Potential role of nitric oxide and lipid peroxidation

Mercer, D. W., Smith, G. S., Cross, J. M., Russell, D. H., Chang, L. & Cacioppo, J., Jun 1996, In : Journal of Surgical Research. 63, 1, p. 185-192 8 p.

Research output: Contribution to journalArticle

62 Scopus citations

Effects of poloxamer 188 on human PMN cells

Harting, M. T., Jimenez, F., Kozar, R. A., Moore, F. A., Mercer, D. W., Hunter, R. L., Cox, C. S. & Gonzalez, E. A., Aug 1 2008, In : Surgery. 144, 2, p. 198-203 6 p.

Research output: Contribution to journalArticle

13 Scopus citations

Effects of polyunsaturated fatty acids on bile acid-induced gastric mucosal injury

Mercer, D. W., Ritchie, W. P. & Dempsey, D. T., Feb 15 1996, In : Journal of Surgical Research. 61, 1, p. 44-50 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

Effects of topical isoproterenol on bile acid-induced gastric mucosal injury

Mercer, D. W., Podolsky, R. S., Ritchie, W. P. & Dempsey, D. T., Jan 1 1993, In : American Surgeon. 59, 8, p. 479-483 5 p.

Research output: Contribution to journalArticle

Farm Machinery Injuries: The 15-Year Experience at an Urban Joint Trauma Center System in a Rural State

Jawa, R. S., Young, D. H., Stothert, J. C., Yetter, D., Dumond, R., Shostrom, V. K., Cemaj, S., Rautiainen, R. H. & Mercer, D. W., Apr 1 2013, In : Journal of Agromedicine. 18, 2, p. 98-106 9 p.

Research output: Contribution to journalArticle

24 Scopus citations

Fasting exacerbates and feeding diminishes LPS-induced liver injury in the rat

Adams, S. D., Delano, B. A., Helmer, K. S. & Mercer, D. W., Apr 1 2009, In : Digestive Diseases and Sciences. 54, 4, p. 767-773 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

Gastric alkalinization after major trauma

Cocanour, C. S., Dial, E. D., Lichtenberger, L. M., Gonzalez, E. A., Kozar, R. A., Moore, F. A. & Mercer, D. W., Mar 1 2008, In : Journal of Trauma - Injury, Infection and Critical Care. 64, 3, p. 681-687 7 p.

Research output: Contribution to journalArticle

4 Scopus citations

Gastric injury induced by ethanol and Ischemia-Reperfusion in the rat: Differing roles for lipid peroxidation and oxygen radicals

Smith, G. S., Mercer, D. W., Cross, J. M., Barreto, J. C. & Miller, T. A., Jul 22 1996, In : Digestive Diseases and Sciences. 41, 6, p. 1157-1164 8 p.

Research output: Contribution to journalArticle

55 Scopus citations

Gastric nitric oxide synthase expression during endotoxemia: Implications in mucosal defense in rats

Helmer, K. S., West, S. D., Shipley, G. L., Chang, L., Cui, Y., Mailman, D. & Mercer, D. W., Jan 1 2002, In : Gastroenterology. 123, 1, p. 173-186 14 p.

Research output: Contribution to journalArticle

39 Scopus citations

Gastroprotective actions of bombesin L-DOPA, and mild irritants: Roles of prostaglandins and sensory neurons

Mercer, D. W., Cross, J. M., Castaneda, A. A. & Gunter, J. A., Jan 1 1998, In : Surgery. 124, 5, p. 864-870 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

Hypertonic saline resuscitation after mesenteric ischemia/reperfusion induces ileal apoptosis

Gonzalez, E. A., Kozar, R. A., Suliburk, J. W., Weisbrodt, N. W., Mercer, D. W. & Moore, F. A., Nov 1 2005, In : Journal of Trauma - Injury, Infection and Critical Care. 59, 5, p. 1092-1098 7 p.

Research output: Contribution to journalArticle

10 Scopus citations

Hypotension during Septic Shock Does Not Correlate with Plasma Levels of Nitric Oxide Metabolites in the Conscious Rat

Klemm, K., Mercer, D. W., Mailman, D. & Moody, F. G., Jan 1 1997, In : Journal of Gastrointestinal Surgery. 1, 4, p. 347-356 10 p.

Research output: Contribution to journalArticle

13 Scopus citations

Image of the month

Liu, T. H., Mehall, J. R. & Mercer, D. W., Jan 1 2001, In : Archives of Surgery. 136, 12, p. 1437-1438 2 p.

Research output: Contribution to journalArticle

9 Scopus citations