Deborah M Brown

  • 2247 Citations
  • 24 h-Index
1989 …2020

Research output per year

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Research Output

  • 2247 Citations
  • 24 h-Index
  • 43 Article
  • 6 Review article
  • 1 Comment/debate
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Article
2020

Analysis of Student Perceptions of Just-In-Time Teaching Pedagogy in PharmD Microbiology and Immunology Courses

Madiraju, C., Tellez-Corrales, E., Hua, H., Stec, J., Nauli, A. M. & Brown, D. M., Feb 28 2020, In : Frontiers in immunology. 11, 351.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Combined TLR4 and TLR9 agonists induce distinct phenotypic changes in innate immunity in vitro and in vivo

Lampe, A. T., Puniya, B. L., Pannier, A. K., Helikar, T. & Brown, D. M., Sep 2020, In : Cellular Immunology. 355, 104149.

Research output: Contribution to journalArticle

2018

A mechanistic computational model reveals that plasticity of CD4+ T cell differentiation is a function of cytokine composition and dosage

Puniya, B. L., Todd, R. G., Mohammed, A., Brown, D. M., Barberis, M. & Helikar, T., Aug 2 2018, In : Frontiers in Physiology. 9, AUG, 878.

Research output: Contribution to journalArticle

5 Scopus citations
2017
6 Scopus citations
21 Scopus citations
2016

Micro- and nanoparticulates for DNA vaccine delivery

Farris, E., Brown, D. M., Ramer-Tait, A. E. & Pannier, A. K., 2016, In : Experimental Biology and Medicine. 241, 9, p. 919-929 11 p.

Research output: Contribution to journalArticle

21 Scopus citations

Significant role for IRF3 in both T cell and APC effector functions during T cell responses

Guinn, Z., Lampe, A. T., Brown, D. M. & Petro, T. M., Dec 1 2016, In : Cellular Immunology. 310, p. 141-149 9 p.

Research output: Contribution to journalArticle

8 Scopus citations
2015

IRF3 deficiency impacts granzyme B expression and maintenance of memory T cell function in response to viral infection

Moore, T. C., Vogel, A. J., Petro, T. M. & Brown, D. M., 2015, In : Microbes and Infection. 17, 6, p. 426-439 14 p.

Research output: Contribution to journalArticle

6 Scopus citations
8 Scopus citations
2014

Early cytokine dysregulation and viral replication are associated with mortality during lethal influenza infection

Vogel, A. J., Harris, S., Marsteller, N., Condon, S. A. & Brown, D. M., Jun 1 2014, In : Viral Immunology. 27, 5, p. 214-224 11 p.

Research output: Contribution to journalArticle

15 Scopus citations

Inflammation enhances IL-2 driven differentiation of cytolytic CD4 T cells

Workman, A. M., Jacobs, A. K., Vogel, A. J., Condon, S. & Brown, D. M., Feb 20 2014, In : PloS one. 9, 2, e89010.

Research output: Contribution to journalArticle

21 Scopus citations

Interferon response factor 3 is crucial to poly-I: C induced NK cell activity and control of B16 melanoma growth

Moore, T. C., Kumm, P. M., Brown, D. M. & Petro, T. M., Apr 28 2014, In : Cancer Letters. 346, 1, p. 122-128 7 p.

Research output: Contribution to journalArticle

12 Scopus citations
2013

IRF3 helps control acute TMEV infection through IL-6 expression but contributes to acute hippocampus damage following TMEV infection

Moore, T. C., Cody, L., Kumm, P. M., Brown, D. M. & Petro, T. M., Dec 26 2013, In : Virus Research. 178, 2, p. 226-233 8 p.

Research output: Contribution to journalArticle

16 Scopus citations
2012
21 Scopus citations

Coxsackievirus B3 infection leads to the generation of cardiac myosin heavy chain-α-reactive CD4 T cells in A/J mice

Gangaplara, A., Massilamany, C., Brown, D. M., Delhon, G., Pattnaik, A. K., Chapman, N., Rose, N., Steffen, D. & Reddy, J., Sep 2012, In : Clinical Immunology. 144, 3, p. 237-249 13 p.

Research output: Contribution to journalArticle

38 Scopus citations

Memory CD4 + T cells protect against influenza through multiple synergizing mechanisms

McKinstry, K. K., Strutt, T. M., Kuang, Y., Brown, D. M., Sell, S., Dutton, R. W. & Swain, S. L., Aug 1 2012, In : Journal of Clinical Investigation. 122, 8, p. 2847-2856 10 p.

Research output: Contribution to journalArticle

122 Scopus citations

Multifunctional CD4 cells expressing gamma interferon and perforin mediate protection against lethal influenza virus infection

Brown, D. M., Lee, S., de la Luz Garcia-Hernandez, M. & Swain, S. L., Jul 2012, In : Journal of virology. 86, 12, p. 6792-6803 12 p.

Research output: Contribution to journalArticle

130 Scopus citations
2011

IRF3 polymorphisms induce different innate anti-Theiler's virus immune responses in RAW264.7 macrophages

Moore, T. C., Al-Salleeh, F. M., Brown, D. M. & Petro, T. M., Sep 15 2011, In : Virology. 418, 1, p. 40-48 9 p.

Research output: Contribution to journalArticle

11 Scopus citations
2009

IL-2 and antigen dose differentially regulate perforin- and FasL-mediated cytolytic activity in antigen specific CD4+ T cells

Brown, D. M., Kamperschroer, C., Dilzer, A. M., Roberts, D. M. & Swain, S. L., 2009, In : Cellular Immunology. 257, 1-2, p. 69-79 11 p.

Research output: Contribution to journalArticle

70 Scopus citations
2007

Persistent depots of influenza antigen fail to induce a cytotoxic CD8 T cell response

Jelley-Gibbs, D. M., Dibble, J. P., Brown, D. M., Strutt, T. M., McKinstry, K. K. & Swain, S. L., Jun 15 2007, In : Journal of Immunology. 178, 12, p. 7563-7570 8 p.

Research output: Contribution to journalArticle

Open Access
52 Scopus citations

Unique ability of activated CD4+ T cells but not rested effectors to migrate to non-lymphoid sites in the absence of inflammation

Agrewala, J. N., Brown, D. M., Lepak, N. M., Duso, D., Huston, G. & Swain, S. L., Mar 2 2007, In : Journal of Biological Chemistry. 282, 9, p. 6106-6115 10 p.

Research output: Contribution to journalArticle

28 Scopus citations
2006

CD4 T cell-mediated protection from lethal influenza: Perform and antibody-mediated mechanisms give a one-two punch

Brown, D. M., Dilzer, A. M., Meents, D. L. & Swain, S. L., Sep 1 2006, In : Journal of Immunology. 177, 5, p. 2888-2898 11 p.

Research output: Contribution to journalArticle

Open Access
213 Scopus citations

Uneven distribution of MHC class II epitopes within the influenza virus

Crowe, S. R., Miller, S. C., Brown, D. M., Adams, P. S., Dutton, R. W., Harmsen, A. G., Lund, F. E., Randall, T. D., Swain, S. L. & Woodland, D. L., Jan 23 2006, In : Vaccine. 24, 4, p. 457-467 11 p.

Research output: Contribution to journalArticle

59 Scopus citations
2005

Unexpected prolonged presentation of influenza antigens promotes CD4 T cell memory generation

Jelley-Gibbs, D. M., Brown, D. M., Dibble, J. P., Haynes, L., Eaton, S. M. & Swain, S. L., Sep 5 2005, In : Journal of Experimental Medicine. 202, 5, p. 697-706 10 p.

Research output: Contribution to journalArticle

188 Scopus citations
2004

CD8 + T cells responding to influenza infection reach and persist at higher numbers than CD4 + T cells independently of precursor frequency

Powell, T. J., Brown, D. M., Hollenbaugh, J. A., Charbonneau, T., Kemp, R. A., Swain, S. L. & Dutton, R. W., Oct 2004, In : Clinical Immunology. 113, 1, p. 89-100 12 p.

Research output: Contribution to journalArticle

31 Scopus citations
2002

Generation of monoclonal antibodies specific for human kallikrein 2 (hK2) using hK2-expressing tumors

Fisher, T. L., Nocera, M., Willis, R. A., Turner, M. J., Siddiq Abdul Alim, C., Brown, D. M., Bourne, P. A., Anthony Di Sant'Agnese, P., Messing, E. M., Lord, E. M. & Frelinger, J. G., May 15 2002, In : Prostate. 51, 3, p. 153-165 13 p.

Research output: Contribution to journalArticle

5 Scopus citations

Regulation of memory CD4 T cells: Generation, localization and persistence

Swain, S. L., Agrewala, J. N., Brown, D. M. & Román, E., 2002, In : Advances in experimental medicine and biology. 512, p. 113-120 8 p.

Research output: Contribution to journalArticle

24 Scopus citations
2001

Human papillomavirus virus-like particles are efficient oral immunogens when coadministered with Escherichia coli heat-labile enterotoxin mutant R192G or CpG DNA

Gerber, S., Lane, C., Brown, D. M., Lord, E., Dilorenzo, M., Clements, J. D., Rybicki, E., Williamson, A. L. & Rose, R. C., 2001, In : Journal of virology. 75, 10, p. 4752-4760 9 p.

Research output: Contribution to journalArticle

86 Scopus citations

Tumours can act as adjuvants for humoral immunity

Brown, D. M., Fisher, T. L., Wei, C., Frelinger, J. G. & Lord, E. M., 2001, In : Immunology. 102, 4, p. 486-497 12 p.

Research output: Contribution to journalArticle

66 Scopus citations
1997

Antibody cross-linking of the thymocyte-specific cell surface molecule CTX causes abnormal mitosis and multinucleation of tumor cells

Robert, J., Brown, D. M., Pasquier, L. D. & Cohen, N., Aug 25 1997, In : Experimental Cell Research. 235, 1, p. 227-237 11 p.

Research output: Contribution to journalArticle

8 Scopus citations

Prostaglandin E2 mediated apoptosis in subsets of malignant B lymphoma cells

Brown, D. M. & Phipps, R. P., 1997, In : Advances in experimental medicine and biology. 400, B, p. 565-570 6 p.

Research output: Contribution to journalArticle

4 Scopus citations
1996

A molecular analysis of PGE receptor (EP) expression on normal and transformed B lymphocytes: Coexpression of EP1, EP2, EP and EP4

Fedyk, E. R., Ripper, J. M., Brown, D. M. & Phipps, R. P., Jan 1996, In : Molecular Immunology. 33, 1, p. 33-45 13 p.

Research output: Contribution to journalArticle

49 Scopus citations

Bcl-2 Expression Inhibits Prostaglandin E2-Mediated Apoptosis in B Cell Lymphomas

Brown, D. M. & Phipps, R. P., Aug 15 1996, In : Journal of Immunology. 157, 4, p. 1359-1370 12 p.

Research output: Contribution to journalArticle

28 Scopus citations
16 Scopus citations
1995

Characterization and regulation of prostaglandin E2 receptors on normal and malignant murine B lymphocytes

Brown, D. M. & Phipps, R. P., Mar 1995, In : Cellular Immunology. 161, 1, p. 79-87 9 p.

Research output: Contribution to journalArticle

21 Scopus citations

Prostaglandin E2 promotes B lymphocyte Ig isotype switching to IgE

Roper, R. L., Brown, D. M. & Phipps, R. P., 1995, In : Journal of Immunology. 154, 1, p. 162-170 9 p.

Research output: Contribution to journalArticle

118 Scopus citations
1993

Strategies for Studying the Regulation of B Lymphocytes by Prostaglandin E2

Borrello, M. A., Fedyk, E. R., Brown, D. M. & Phipps, R. P., Jun 1993, In : ImmunoMethods. 2, 3, p. 261-272 12 p.

Research output: Contribution to journalArticle

4 Scopus citations
1992

Differential collagen and fibronectin production by Thy 1+ and Thy 1- lung fibroblast subpopulations

Derdak, S., Penney, D. P., Keng, P., Felch, M. E., Brown, D. & Phipps, R. P., 1992, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 263, 2 7-2, p. L283-L290

Research output: Contribution to journalArticle

56 Scopus citations

Prostaglandin E2 induces apoptosis in immature normal and malignant B lymphocytes

Brown, D. M., Warner, G. L., Alés-Martínez, J. E., Scott, D. W. & Phipps, R. P., Jun 1992, In : Clinical Immunology and Immunopathology. 63, 3, p. 221-229 9 p.

Research output: Contribution to journalArticle

80 Scopus citations
1990

Differential expression of interleukin 1α by Thy‐1+ and Thy‐1 lung fibroblast subpopulations: Enhancement of interleukin 1α production by tumor necrosis factor‐α

Phipps, R. P., Baecher, C., Frelinger, J. G., Penney, D. P., Keng, P. & Brown, D., Aug 1990, In : European Journal of Immunology. 20, 8, p. 1723-1727 5 p.

Research output: Contribution to journalArticle

45 Scopus citations

Prostaglandin E2 promotes IL-4-induced IgE and IgG1 synthesis

Roper, R. L., Conrad, D. H., Brown, D. M., Warner, G. L. & Phipps, R. P., 1990, In : Journal of Immunology. 145, 8, p. 2644-2651 8 p.

Research output: Contribution to journalArticle

121 Scopus citations
1989

Synergistic activation of granulocyte-macrophage colony-stimulating factor production by IL-1 and IL-2 in murine Th1 cells

Quill, H., Gaur, A., Brown, D., Infante, A. J. & Phipps, R. P., 1989, In : Journal of Immunology. 143, 7, p. 2242-2247 6 p.

Research output: Contribution to journalArticle

12 Scopus citations