• 2901 Citations
  • 30 h-Index
20002020

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Article
2008

Synthesis and evaluation of a well-defined HPMA copolymer-dexamethasone conjugate for effective treatment of rheumatoid arthritis

Liu, X. M., Quan, L. D., Tian, J., Alnouti, Y., Fu, K., Thiele, G. M. & Wang, D., Dec 2008, In : Pharmaceutical Research. 25, 12, p. 2910-2919 10 p.

Research output: Contribution to journalArticle

78 Scopus citations

Targeted delivery for musculoskeletal diseases

Wang, D., Dec 2008, In : Pharmaceutical Research. 25, 12, p. 2878-2880 3 p.

Research output: Contribution to journalArticle

2 Scopus citations
2007

Efficient synthesis of linear multifunctional poly(ethylene glycol) by copper(I)-catalyzed Huisgen 1,3-dipolar cycloaddition

Liu, X. M., Thakur, A. & Wang, D., Sep 2007, In : Biomacromolecules. 8, 9, p. 2653-2658 6 p.

Research output: Contribution to journalArticle

74 Scopus citations

Novel biomineral-binding cyclodextrins for controlled drug delivery in the oral cavity

Liu, X. M., Lee, H. T., Reinhardt, R. A., Marky, L. A. & Wang, D., Sep 11 2007, In : Journal of Controlled Release. 122, 1, p. 54-62 9 p.

Research output: Contribution to journalArticle

38 Scopus citations

Novel dexamethasone-HPMA copolymer conjugate and its potential application in treatment of rheumatoid arthritis

Wang, D., Miller, S. C., Liu, X. M., Anderson, B., Wang, X. S. & Goldring, S. R., 2007, In : Arthritis Research and Therapy. 9, R2.

Research output: Contribution to journalArticle

97 Scopus citations

Osteotropic peptide that differentiates functional domains of the skeleton

Wang, D., Miller, S. C., Shlyakhtenko, L. S., Portillo, A. M., Liu, X. M., Papangkorn, K., Kopečková, P., Lyubchenko, Y., Higuchi, W. I. & Kopeček, J., Sep 2007, In : Bioconjugate Chemistry. 18, 5, p. 1375-1378 4 p.

Research output: Contribution to journalArticle

71 Scopus citations

Stability in plasmas of various species of HPMA copolymer-PGE1 conjugates

Pan, H., Kopečková, P., Liu, J., Wang, D., Miller, S. C. & Kopeček, J., Dec 2007, In : Pharmaceutical Research. 24, 12, p. 2270-2280 11 p.

Research output: Contribution to journalArticle

21 Scopus citations
2006

Pharmacokinetic and biodistribution studies of a bone-targeting drug delivery system based on N-(2-hydroxypropyl)methacrylamide copolymers

Wang, D., Sima, M., Mosley, R. L., Davda, J. P., Tietze, N., Miller, S. C., Gwilt, P. R., Kopečková, P. & Kopeček, J., Nov 2006, In : Molecular Pharmaceutics. 3, 6, p. 717-725 9 p.

Research output: Contribution to journalArticle

75 Scopus citations

Synthesis and characterization of novel aromatic azo bond-containing pH-sensitive and hydrolytically cleavable IPN hydrogels

Chivukula, P., Dušek, K., Wang, D., Dušková-Smršková, M., Kopečková, P. & Kopeček, J., Mar 2006, In : Biomaterials. 27, 7, p. 1140-1151 12 p.

Research output: Contribution to journalArticle

47 Scopus citations

Water-soluble HPMA copolymer - Prostaglandin E1 conjugates containing a cathepsin K sensitive spacer

Pan, H., Kopečková, P., Wang, D., Yang, J., Miller, S. & Kopeček, J., Jul 2006, In : Journal of Drug Targeting. 14, 6, p. 425-435 11 p.

Research output: Contribution to journalArticle

45 Scopus citations
2005

Biopolymer-based delivery systems for advanced imaging and skeletal tissue-specific therapeutics

Miller, S. C., Wang, D., Kopečková, P. & Kopeček, J., Jan 2005, In : Journal of Bone and Mineral Metabolism. 23, SUPPL. 1, p. 103-108 6 p.

Research output: Contribution to journalArticle

4 Scopus citations
2004

Cathepsin K inhibitor-polymer conjugates: Potential drugs for the treatment of osteoporosis and rheumatoid arthritis

Wang, D., Li, W., Pechar, M., Kopečková, P., Brömme, D. & Kopeček, J., Jun 11 2004, In : International journal of pharmaceutics. 277, 1-2, p. 73-79 7 p.

Research output: Contribution to journalArticle

27 Scopus citations

The arthrotropism of macromolecules in adjuvant-induced arthritis rat model: A preliminary study

Wang, D., Miller, S. C., Sima, M., Parker, D., Buswell, H., Goodrich, K. C., Kopečková, P. & Kopeček, J., Oct 2004, In : Pharmaceutical Research. 21, 10, p. 1741-1749 9 p.

Research output: Contribution to journalArticle

50 Scopus citations
2003

Synthesis and evaluation of water-soluble polymeric bone-targeted drug delivery systems

Wang, D., Miller, S., Sima, M., Kopečková, P. & Kopeček, J., Sep 2003, In : Bioconjugate Chemistry. 14, 5, p. 853-859 7 p.

Research output: Contribution to journalArticle

137 Scopus citations
2002

Inhibition of cathepsin K with lysosomotropic macromolecular inhibitors

Wang, D., Pechar, M., Li, W., Kopečková, P., Brömme, D. & Kopeček, J., Jul 16 2002, In : Biochemistry. 41, 28, p. 8849-8859 11 p.

Research output: Contribution to journalArticle

39 Scopus citations

Novel aromatic azo-containing pH-sensitive hydrogels: Synthesis and characterization

Wang, D., Dušek, K., Kopečková, P., Dušková-Smrčková, M. & Kopeček, J., Sep 24 2002, In : Macromolecules. 35, 20, p. 7791-7803 13 p.

Research output: Contribution to journalArticle

33 Scopus citations
2000

Synthesis of starlike N-(2-hydroxypropyl)methacrylamide copolymers: Potential drug carriers

Wang, D., Kopečková, P., Minko, T., Nanayakkara, V. & Kopeček, J., 2000, In : Biomacromolecules. 1, 3, p. 313-319 7 p.

Research output: Contribution to journalArticle

91 Scopus citations