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Research Output

2020

Loss of NQO1 generates genotoxic estrogen-DNA adducts in Fuchs Endothelial Corneal Dystrophy

Miyajima, T., Melangath, G., Zhu, S., Deshpande, N., Vasanth, S., Mondal, B., Kumar, V., Chen, Y., Price, M. O., Price, F. W., Rogan, E. G., Zahid, M. & Jurkunas, U. V., Feb 1 2020, In : Free Radical Biology and Medicine. 147, p. 69-79 11 p.

Research output: Contribution to journalArticle

2 Scopus citations

Ultraviolet A light induces DNA damage and estrogen-DNA adducts in Fuchs endothelial corneal dystrophy causing females to be more affected

Liu, C., Miyajima, T., Melangath, G., Miyai, T., Vasanth, S., Deshpande, N., Kumar, V., Tone, S. O., Gupta, R., Zhu, S., Vojnovic, D., Chen, Y., Rogan, E. G., Mondal, B., Zahid, M. & Jurkunas, U. V., Jan 7 2020, In : Proceedings of the National Academy of Sciences of the United States of America. 117, 1, p. 573-583 11 p.

Research output: Contribution to journalArticle

2 Scopus citations
2019

Estrogen Metabolism in African-American Women with and without Breast Cancer: A Pilot Study

Zahid, M., Mondal, B., Levan, T. D. & Rogan, E. G., Jan 22 2019, In : Chemical Research in Toxicology. 32, 1, p. 190-194 5 p.

Research output: Contribution to journalArticle

Role of Estrogen in Androgen-Induced Prostate Carcinogenesis in NBL Rats

Ozten, N., Vega, K., Liehr, J., Huang, X., Horton, L., Cavalieri, E. L., Rogan, E. G. & Bosland, M. C., Jan 1 2019, In : Hormones and Cancer.

Research output: Contribution to journalArticle

5 Scopus citations
2018

Modulation of Cellular Response to Arsenic Trioxide Toxicity by Resveratrol

Mondal, B., Chen, H., Wen, W., Cavalieri, E. L., Rogan, E. G. & Zahid, M., May 21 2018, In : ACS Omega. 3, 5, p. 5511-5515 5 p.

Research output: Contribution to journalArticle

4 Scopus citations
4 Scopus citations

Using Watershed Boundaries to Map Adverse Health Outcomes: Examples From Nebraska, USA

Corley, B., Bartelt-Hunt, S., Rogan, E., Coulter, D., Sparks, J., Baccaglini, L., Howell, M., Liaquat, S., Commack, R. & Kolok, A. S., 2018, In : Environmental Health Insights. 12

Research output: Contribution to journalArticle

Open Access
2017
15 Scopus citations
2016

Inhibition of depurinating estrogen-DNA adduct formation in the prevention of breast and other cancers

Cavalieri, E. L. & Rogan, E. G., Jan 1 2016, Trends in Breast Cancer Prevention. Springer International Publishing, p. 113-145 33 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations
2015

Breast health and reducing breast cancer risk: A functional medicine approach

Muran, P. J., Muran, S. Y., Beseler, C. L., Cavalieri, E. L., Rogan, E. G. & Zahid, M., Jun 1 2015, In : Journal of Alternative and Complementary Medicine. 21, 6, p. 321-326 6 p.

Research output: Contribution to journalArticle

2 Scopus citations

IDH2R172 mutations define a unique subgroup of patients with angioimmunoblastic T-cell lymphoma

Wang, C., McKeithan, T. W., Gong, Q., Zhang, W., Bouska, A., Rosenwald, A., Gascoyne, R. D., Wu, X., Wang, J., Muhammad, Z., Jiang, B., Rohr, J., Cannon, A., Steidl, C., Fu, K., Li, Y., Hung, S., Weisenburger, D. D., Greiner, T. C., Smith, L. & 6 others, Ott, G., Rogan, E. G., Staudt, L. M., Vose, J., Iqbal, J. & Chan, W. C., Oct 8 2015, In : Blood. 126, 15, p. 1741-1752 12 p.

Research output: Contribution to journalArticle

86 Scopus citations

Oxidative metabolism of estrogens in cancer initiation and prevention

Rogan, E. G. & Cavalieri, E. L., 2015, Oxidative Stress: Diagnostics, Prevention, and Therapy Volume 2. Andreescu, S. & Hepel, M. (eds.). American Chemical Society, p. 35-51 17 p. (ACS Symposium Series; vol. 1200).

Research output: Chapter in Book/Report/Conference proceedingChapter

2014

Diallyl sulfide inhibits diethylstilbestrol induced DNA damage in human breast epithelial cells (MCF-10A)

McCaskill, M. L., Rogan, E. & Thomas, R. D., Dec 15 2014, In : Steroids. 92, p. 96-100 5 p.

Research output: Contribution to journalArticle

9 Scopus citations
50 Scopus citations

Unbalanced estrogen metabolism in ovarian cancer

Zahid, M., Beseler, C. L., Hall, J. B., LeVan, T., Cavalieri, E. L. & Rogan, E. G., May 15 2014, In : International Journal of Cancer. 134, 10, p. 2414-2423 10 p.

Research output: Contribution to journalArticle

19 Scopus citations
2013

Reduced formation of depurinating estrogen-DNA adducts by sulforaphane or KEAP1 disruption in human mammary epithelial MCF-10A cells

Yang, L., Zahid, M., Liao, Y., Rogan, E. G., Cavalieri, E. L., Davidson, N. E., Yager, J. D., Visvanathan, K., Groopman, J. D. & Kensler, T. W., Nov 2013, In : Carcinogenesis. 34, 11, p. 2587-2592 6 p.

Research output: Contribution to journalArticle

20 Scopus citations

Unbalanced estrogen metabolism in thyroid cancer

Zahid, M., Goldner, W., Beseler, C. L., Rogan, E. G. & Cavalieri, E. L., Dec 1 2013, In : International Journal of Cancer. 133, 11, p. 2642-2649 8 p.

Research output: Contribution to journalArticle

32 Scopus citations
2012

Evaluation of serum estrogen-DNA adducts as potential biomarkers for breast cancer risk

Pruthi, S., Yang, L., Sandhu, N. P., Ingle, J. N., Beseler, C. L., Suman, V. J., Cavalieri, E. L. & Rogan, E. G., Oct 2012, In : Journal of Steroid Biochemistry and Molecular Biology. 132, 1-2, p. 73-79 7 p.

Research output: Contribution to journalArticle

25 Scopus citations

Mechanism of DNA depurination by carcinogens in relation to cancer initiation

Cavalieri, E., Saeed, M., Zahid, M., Cassada, D., Snow, D., Miljkovic, M. & Rogan, E., Feb 2012, In : IUBMB Life. 64, 2, p. 169-179 11 p.

Research output: Contribution to journalArticle

18 Scopus citations

Preface

Cavalieri, E. & Rogan, E. G., 2012, In : Drug Discovery Today: Disease Mechanisms. 9, 1-2, p. e1-e3

Research output: Contribution to journalEditorial

The etiology and prevention of breast cancer

Cavalieri, E. L. & Rogan, E. G., Jun 2012, In : Drug Discovery Today: Disease Mechanisms. 9, 1-2, p. e55-e69

Research output: Contribution to journalReview article

8 Scopus citations
2011

Formation of diethylstilbestrol-DNA adducts in human breast epithelial cells and inhibition by resveratrol

Hinrichs, B., Zahid, M., Saeed, M., Ali, M. F., Cavalieri, E. L. & Rogan, E. G., Nov 2011, In : Journal of Steroid Biochemistry and Molecular Biology. 127, 3-5, p. 276-281 6 p.

Research output: Contribution to journalArticle

14 Scopus citations

Formation of dopamine quinone-DNA adducts and their potential role in the etiology of Parkinson's disease

Zahid, M., Saeed, M., Yang, L., Beseler, C., Rogan, E. & Cavalieri, E. L., Dec 2011, In : IUBMB Life. 63, 12, p. 1087-1093 7 p.

Research output: Contribution to journalArticle

22 Scopus citations

Imbalanced estrogen metabolism in the brain: Possible relevance to the etiology of Parkinson's disease

Gaikwad, N. W., Murman, D., Beseler, C. L., Zahid, M., Rogan, E. G. & Cavalieri, E. L., Aug 2011, In : Biomarkers. 16, 5, p. 434-444 11 p.

Research output: Contribution to journalArticle

9 Scopus citations

Oxidative stress in the metabolism of estrogens leading to cancer initiation: Prevention by specific antioxidants

Rogan, E. G. & Cavalieri, E. L., Nov 17 2011, Oxidative Stress: Diagnostics, Prevention, and Therapy. American Chemical Society, p. 83-98 16 p. (ACS Symposium Series; vol. 1083).

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Resveratrol and N-acetylcysteine block the cancer-initiating step in MCF-10F cells

Zahid, M., Saeed, M., Beseler, C., Rogan, E. G. & Cavalieri, E. L., Jan 1 2011, In : Free Radical Biology and Medicine. 50, 1, p. 78-85 8 p.

Research output: Contribution to journalArticle

26 Scopus citations

Tetra-methoxystilbene modulates ductal growth of the developing murine mammary gland

Kim, T., Park, H., Yue, W., Wang, J. P., Atkins, K. A., Zhang, Z., Rogan, E. G., Cavalieri, E. L., Mohammad, K. S., Kim, S., Santen, R. J. & Aiyar, S. E., Apr 2011, In : Breast Cancer Research and Treatment. 126, 3, p. 779-789 11 p.

Research output: Contribution to journalArticle

13 Scopus citations

The role of specific estrogen metabolites in the initiation of breast and other human cancers

Rogan, E. G. & Cavalieri, E. L., Jan 2011, Metabolomics: Metabolites, Metabonomics, and Analytical Technologies. Nova Science Publishers, Inc., p. 243-252 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations
97 Scopus citations
2010

Benzene and dopamine catechol quinones could initiate cancer or neurogenic disease

Zahid, M., Saeed, M., Rogan, E. G. & Cavalieri, E. L., Jan 15 2010, In : Free Radical Biology and Medicine. 48, 2, p. 318-324 7 p.

Research output: Contribution to journalArticle

20 Scopus citations

Depurinating estrogen-DNA adducts in the etiology and prevention of breast and other human cancers

Cavalieri, E. L. & Rogan, E. G., 2010, In : Future Oncology. 6, 1, p. 75-91 17 p.

Research output: Contribution to journalReview article

65 Scopus citations

Is bisphenol A a weak carcinogen like the natural estrogens and diethylstilbestrol?

Cavalieri, E. L. & Rogan, E. G., Oct 2010, In : IUBMB Life. 62, 10, p. 746-751 6 p.

Research output: Contribution to journalArticle

25 Scopus citations

N-acetylcysteine blocks formation of cancer-initiating estrogen-DNA adducts in cells

Zahid, M., Saeed, M., Ali, M. F., Rogan, E. G. & Cavalieri, E. L., Aug 2010, In : Free Radical Biology and Medicine. 49, 3, p. 392-400 9 p.

Research output: Contribution to journalArticle

22 Scopus citations
2009

Depurinating naphthalene-DNA adducts in mouse skin related to cancer initiation

Saeed, M., Higginbotham, S., Gaikwad, N., Chakravarti, D., Rogan, E. & Cavalieri, E., Oct 1 2009, In : Free Radical Biology and Medicine. 47, 7, p. 1075-1081 7 p.

Research output: Contribution to journalArticle

29 Scopus citations

Estrogen mediation of breast tumor formation involves estrogen receptor-dependent, as well as independent, genotoxic effects

Santen, R., Cavalieri, E., Rogan, E., Russo, J., Guttenplan, J., Ingle, J. & Yue, W., Feb 2009, Steroid Enzymes and Cancer. Blackwell Publishing Inc., p. 132-140 9 p. (Annals of the New York Academy of Sciences; vol. 1155).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

61 Scopus citations

Evidence for NQO2-mediated reduction of the carcinogenic estrogen ortho-quinones

Gaikwad, N. W., Yang, L., Rogan, E. G. & Cavalieri, E. L., Jan 15 2009, In : Free Radical Biology and Medicine. 46, 2, p. 253-262 10 p.

Research output: Contribution to journalArticle

46 Scopus citations
36 Scopus citations
11 Scopus citations

Novel biomarkers for risk of prostate cancer: Results from a case-control study

Yang, L., Gaikwad, N. W., Meza, J., Cavalieri, E. L., Muti, P., Trock, B. & Rogan, E. G., Jan 1 2009, In : Prostate. 69, 1, p. 41-48 8 p.

Research output: Contribution to journalArticle

34 Scopus citations

Urinary biomarkers suggest that estrogen-DNA adducts may play a role in the aetiology of non-Hodgkin lymphoma

Gaikwad, N. W., Yang, L., Weisenburger, D. D., Vose, J., Beseler, C., Rogan, E. G. & Cavalieri, E. L., 2009, In : Biomarkers. 14, 7, p. 502-512 11 p.

Research output: Contribution to journalArticle

24 Scopus citations

Urine biomarkers of risk in the molecular etiology of breast cancer

Gaikwad, N. W., Yang, L., Pruthi, S., Ingle, J. N., Sandhu, N., Rogan, E. G. & Cavalieri, E. L., Jan 6 2009, In : Breast Cancer: Basic and Clinical Research. 3, 1, p. 1-8 8 p.

Research output: Contribution to journalArticle

Open Access
51 Scopus citations
2008

hPMC2 is required for recruiting an ERβ coactivator complex to mediate transcriptional upregulation of NQO1 and protection against oxidative DNA damage by tamoxifen

Sripathy, S. P., Chaplin, L. J., Gaikwad, N. W., Rogan, E. G. & Montano, M. M., Oct 23 2008, In : Oncogene. 27, 49, p. 6376-6384 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

Possible genotoxic modes of action for naphthalene

Brusick, D., Small, M. S., Cavalieri, E. L., Chakravarti, D., Ding, X., Longfellow, D. G., Nakamura, J., Rogan, E. C. & Swenberg, J. A., Jul 2008, In : Regulatory Toxicology and Pharmacology. 51, 2 SUPLL, p. 43-50 8 p.

Research output: Contribution to journalArticle

19 Scopus citations

Prevalence of BER gene polymorphisms in sporadic breast cancer

Ali, M. F., Meza, J. L., Rogan, E. G. & Chakravarti, D., Apr 2008, In : Oncology reports. 19, 4, p. 1033-1038 6 p.

Research output: Contribution to journalArticle

Open Access
20 Scopus citations

Prevention of estrogen-DNA adduct formation in MCF-10F cells by resveratrol

Zahid, M., Gaikwad, N. W., Ali, M. F., Lu, F., Saeed, M., Yang, L., Rogan, E. G. & Cavalieri, E. L., Jul 15 2008, In : Free Radical Biology and Medicine. 45, 2, p. 136-145 10 p.

Research output: Contribution to journalArticle

48 Scopus citations

Reduction of estrogen-induced transformation of mouse mammary epithelial cells by N-acetylcysteine

Venugopal, D., Zahid, M., Mailander, P. C., Meza, J. L., Rogan, E. G., Cavalieri, E. L. & Chakravarti, D., Mar 2008, In : Journal of Steroid Biochemistry and Molecular Biology. 109, 1-2, p. 22-30 9 p.

Research output: Contribution to journalArticle

26 Scopus citations

Resveratrol prevents estrogen-DNA adduct formation and neoplastic transformation in MCF-10F cells

Lu, F., Zahid, M., Wang, C., Saeed, M., Cavalieri, E. L. & Rogan, E. G., Jul 2008, In : Cancer Prevention Research. 1, 2, p. 135-145 11 p.

Research output: Contribution to journalArticle

76 Scopus citations

The molecular etiology of breast cancer: Evidence from biomarkers of risk

Gaikwad, N. W., Yang, L., Muti, P., Meza, J. L., Pruthi, S., Ingle, J. N., Rogan, E. G. & Cavalieri, E. L., May 1 2008, In : International Journal of Cancer. 122, 9, p. 1949-1957 9 p.

Research output: Contribution to journalArticle

100 Scopus citations

The role of polycyclic aromatic hydrocarbon-DNA adducts in inducing mutations in mouse skin

Chakravarti, D., Venugopal, D., Mailander, P. C., Meza, J. L., Higginbotham, S., Cavalieri, E. L. & Rogan, E. G., Jan 8 2008, In : Mutation Research - Genetic Toxicology and Environmental Mutagenesis. 649, 1-2, p. 161-178 18 p.

Research output: Contribution to journalArticle

25 Scopus citations
2007

Cytochrome P450 isoforms catalyze formation of catechol estrogen quinones that react with DNA

Zhang, Y., Gaikwad, N. W., Olson, K., Zahid, M., Cavalieri, E. L. & Rogan, E. G., Jul 2007, In : Metabolism: Clinical and Experimental. 56, 7, p. 887-894 8 p.

Research output: Contribution to journalArticle

37 Scopus citations