• 3667 Citations
  • 27 h-Index
1970 …2020

Research output per year

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Research Output

2020

Alpha-Particle Therapy for Multifocal Osteosarcoma: A Hypothesis

Baranowska-Kortylewicz, J., Sharp, J. G., McGuire, T. R., Joshi, S. & Coulter, D. W., Aug 1 2020, In : Cancer Biotherapy and Radiopharmaceuticals. 35, 6, p. 418-424 7 p.

Research output: Contribution to journalArticle

A Novel Combination Approach Targeting an Enhanced Protein Synthesis Pathway in MYC-driven (Group 3) Medulloblastoma

Chaturvedi, N. K., Kling, M. J., Griggs, C. N., Kesherwani, V., Shukla, M., McIntyre, E. M., Ray, S., Liu, Y., McGuire, T. R., Sharp, J. G., Band, H., Joshi, S. S. & Coulter, D. W., Jun 1 2020, In : Molecular cancer therapeutics. 19, 6, p. 1351-1362 12 p.

Research output: Contribution to journalArticle

Fatty Acid Mediators in the Tumor Microenvironment

Khadge, S., Sharp, J. G., Thiele, G. M., McGuire, T. R. & Talmadge, J. E., 2020, Advances in Experimental Medicine and Biology. Springer, p. 125-153 29 p. (Advances in Experimental Medicine and Biology; vol. 1259).

Research output: Chapter in Book/Report/Conference proceedingChapter

Long non-coding RNA profiling of pediatric Medulloblastoma

Kesherwani, V., Shukla, M., Coulter, D. W., Sharp, J. G., Joshi, S. S., Chaturvedi, N. K. & Chaturvedi, N. K., Jun 26 2020, In : BMC Medical Genomics. 13, 1, 87.

Research output: Contribution to journalArticle

Open Access
2019

Effects of novel pyrrolomycin MP1 in MYCN amplified chemoresistant neuroblastoma cell lines alone and combined with temsirolimus

McGuire, T. R., Coulter, D. W., Bai, D., Sughroue, J. A., Li, J., Yang, Z., Qiao, Z., Liu, Y., Murry, D. J., Chhonker, Y. S., McIntyre, E. M., Alexander, G., Sharp, J. G. & Li, R., Aug 27 2019, In : BMC cancer. 19, 1, 837.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Role of protein arginine methyltransferase 5 in group 3 (MYC-driven) Medulloblastoma

Chaturvedi, N. K., Mahapatra, S., Kesherwani, V., Kling, M. J., Shukla, M., Ray, S., Kanchan, R., Perumal, N., McGuire, T. R., Graham Sharp, J., Joshi, S. S. & Coulter, D. W., Nov 6 2019, In : BMC cancer. 19, 1, 1056.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
2018

Dietary omega-3 and omega-6 polyunsaturated fatty acids modulate hepatic pathology

Khadge, S., Sharp, J. G., Thiele, G. M., McGuire, T. R., Klassen, L. W., Duryee, M. J., Britton, H. C., Dafferner, A. J., Beck, J., Black, P. N., DiRusso, C. C. & Talmadge, J. E., Feb 2018, In : Journal of Nutritional Biochemistry. 52, p. 92-102 11 p.

Research output: Contribution to journalArticle

13 Scopus citations

Immune regulation and anti-cancer activity by lipid inflammatory mediators

Khadge, S., Sharp, J. G., McGuire, T. R., Thiele, G. M., Black, P., DiRusso, C., Cook, L., Klassen, L. W. & Talmadge, J. E., Dec 2018, In : International Immunopharmacology. 65, p. 580-592 13 p.

Research output: Contribution to journalReview article

6 Scopus citations

Improved therapy for medulloblastoma: Targeting hedgehog and PI3K-mTOR signaling pathways in combination with chemotherapy

Chaturvedi, N. K., Kling, M. J., Coulter, D. W., McGuire, T. R., Ray, S., Kesherwani, V., Joshi, S. S. & Sharp, J. G., Mar 30 2018, In : Oncotarget. 9, 24, p. 16619-16633 15 p.

Research output: Contribution to journalArticle

10 Scopus citations
12 Scopus citations
4 Scopus citations

Suppression of STAT3 NH2-terminal domain chemosensitizes medulloblastoma cells by activation of protein inhibitor of activated STAT3 via de-repression by microRNA-21

Ray, S., Coulter, D. W., Gray, S. D., Sughroue, J. A., Roychoudhury, S., Mcintyre, E. M., Chaturvedi, N. K., Bhakat, K. K., Joshi, S. S., McGuire, T. R. & Sharp, J. G., Apr 2018, In : Molecular Carcinogenesis. 57, 4, p. 536-548 13 p.

Research output: Contribution to journalArticle

4 Scopus citations
2017

Challenges and Recent Advances in Medulloblastoma Therapy

Kumar, V., Kumar, V., McGuire, T., Coulter, D. W., Sharp, J. G. & Mahato, R. I., Dec 2017, In : Trends in Pharmacological Sciences. 38, 12, p. 1061-1084 24 p.

Research output: Contribution to journalReview article

26 Scopus citations

Lipid inflammatory mediators in cancer progression and therapy

Khadge, S., Sharp, J. G., McGuire, T. R., Thiele, G. M. & Talmadge, J. E., 2017, Advances in Experimental Medicine and Biology. Springer New York LLC, p. 145-156 12 p. (Advances in Experimental Medicine and Biology; vol. 1036).

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations
2016

Comparing biocompatibility of titanium orthopaedic implants with and without an ultra-thin coating of TiO2 by Ion beam assisted deposition

Miralami, R., Namavar, F., Thiele, G. M., Sharp, J. G. & Garvin, K. L., 2016, Biotech, Biomaterials and Biomedical - TechConnect Briefs 2016. Laudon, M., Case, F., Case, F., Romanowicz, B. & Romanowicz, B. (eds.). TechConnect, p. 43-46 4 p. (Advanced Materials - TechConnect Briefs 2016; vol. 3).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Improved therapy for neuroblastoma using a combination approach: Superior efficacy with vismodegib and topotecan

Chaturvedi, N. K., McGuire, T. R., Coulter, D. W., Shukla, A., McIntyre, E. M., Sharp, J. G. & Joshi, S. S., Mar 22 2016, In : Oncotarget. 7, 12, p. 15215-15229 15 p.

Research output: Contribution to journalArticle

13 Scopus citations

Treatment of a chemoresistant neuroblastoma cell line with the antimalarial ozonide OZ513

Coulter, D. W., McGuire, T. R., Sharp, J. G., McIntyre, E. M., Dong, Y., Wang, X., Gray, S., Alexander, G. R., Chatuverdi, N. K., Joshi, S. S., Chen, X. & Vennerstrom, J. L., Nov 8 2016, In : BMC cancer. 16, 1, 867.

Research output: Contribution to journalArticle

2015

Translational Animal Models for Regenerative Medicine Research

Sharp, J. G., 2015, Translational Regenerative Medicine. Elsevier Inc., p. 243-256 14 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2014

Changes in the frequencies of human hematopoietic stem and progenitor cells with age and site

Farrell, T. L., McGuire, T. R., Bilek, L. D., Brusnahan, S. K., Jackson, J. D., Lane, J. T., Garvin, K. L., O'Kane, B. J., Berger, A. M., Tuljapurkar, S. R., Kessinger, M. A. & Sharp, J. G., Feb 2014, In : Experimental Hematology. 42, 2, p. 146-154 9 p.

Research output: Contribution to journalArticle

5 Scopus citations

Tumor suppressor functions of Dnmt3a and Dnmt3b in the prevention of malignant mouse lymphopoiesis

Peters, S. L., Hlady, R. A., Opavska, J., Klinkebiel, D., Pirruccello, S. J., Talmon, G. A., Sharp, J. G., Wu, L., Jaenisch, R., Simpson, M. A., Karpf, A. R. & Opavsky, R., May 2014, In : Leukemia. 28, 5, p. 1138-1142 5 p.

Research output: Contribution to journalLetter

28 Scopus citations
2013

Comparing biocompatibility of nanocrystalline titanium and titanium-oxide with microcrystalline titanium

Miralami, R., Koepsell, L., Premaraj, T., Kim, B., Thiele, G. M., Sharp, J. G., Garvin, K. L. & Namavar, F., 2013, Materials Research Society Symposium Proceedings. Materials Research Society, Vol. 1569.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Scopus citations

Heterogeneity of functional properties of clone 66 murine breast cancer cells expressing various stem cell phenotypes

Mukhopadhyay, P., Farrell, T., Sharma, G., McGuire, T. R., O'Kane, B. & Sharp, J. G., Nov 12 2013, In : PloS one. 8, 11, e78725.

Research output: Contribution to journalArticle

7 Scopus citations

Nanostructurally designed ultra-hydrophilic hard ceramic oxide coatings for orthopaedic application

Namavar, F., Sabirianov, R. F., Zhang, J., Cheung, C. L., Blatchley, C., Miralami, R., Sharp, J. G. & Garvin, K. L., 2013, Titanium Dioxide: Fundamentals and Applications. Materials Research Society, p. 23-28 6 p. (Materials Research Society Symposium Proceedings; vol. 1578).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations
2012

Engineered nanostructured coatings for enhanced protein adsorption and cell growth

Namavar, F., Rubinstein, A., Sabirianov, R. F., Thiele, G. M., Sharp, J. G., Pokharel, U., Namavar, R. M. & Garvin, K. L., 2012, Gels and Biomedical Materials. p. 119-125 7 p. (Materials Research Society Symposium Proceedings; vol. 1418).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

6 Scopus citations

Novel therapy for therapy-resistant mantle cell lymphoma: Multipronged approach with targeting of hedgehog signaling

Hegde, G. V., Nordgren, T. M., Munger, C. M., Mittal, A. K., Bierman, P. J., Weisenburger, D. D., Vose, J. M., Sharp, J. G. & Joshi, S. S., Dec 15 2012, In : International Journal of Cancer. 131, 12, p. 2951-2960 10 p.

Research output: Contribution to journalArticle

11 Scopus citations

Nucleic Acid and Non-Nucleic Acid-Based Reprogramming of Adult Limbal Progenitors to Pluripotency

Parameswaran, S., Balasubramanian, S., Babai, N., DelDebbio, C. B., Harms, D. W., Gurumurthy, C. B., Rao, M. S., Sharp, J. G. & Ahmad, I., Oct 8 2012, In : PloS one. 7, 10, e46734.

Research output: Contribution to journalArticle

8 Scopus citations
2011

Changes in human bone marrow fat content associated with changes in hematopoietic stem cell numbers and cytokine levels with aging

Tuljapurkar, S. R., Mcguire, T. R., Brusnahan, S. K., Jackson, J. D., Garvin, K. L., Kessinger, M. A., Lane, J. T., O'Kane, B. J. & Sharp, J. G., Nov 2011, In : Journal of Anatomy. 219, 5, p. 574-581 8 p.

Research output: Contribution to journalArticle

56 Scopus citations

Differentiation of embryonic stem cells into fibroblast-like cells in three-dimensional type i collagen gel cultures

Togo, S., Sato, T., Sugiura, H., Wang, X., Basma, H., Nelson, A., Liu, X., Bargar, T. W., Sharp, J. G. & Rennard, S. I., Feb 2011, In : In Vitro Cellular and Developmental Biology - Animal. 47, 2, p. 114-124 11 p.

Research output: Contribution to journalArticle

14 Scopus citations

IL-4 induces differentiation of human embryonic stem cells into fibrogenic fibroblast-like cells

Sato, T., Liu, X., Basma, H., Togo, S., Sugiura, H., Nelson, A., Nakanishi, M., Kanaji, N., Wang, X., Kim, M., Li, Y., Michalski, J., Farid, M., Sharp, J. G. & Rennard, S. I., Jun 2011, In : Journal of Allergy and Clinical Immunology. 127, 6, p. 1595-1603.e9

Research output: Contribution to journalArticle

7 Scopus citations

Inflammation associated with obesity: Relationship with blood and bone marrow endothelial cells

McGuire, T. R., Brusnahan, S. K., Bilek, L. D., Jackson, J. D., Kessinger, M. A., Berger, A. M., Garvin, K. L., O'Kane, B. J., Tuljapurkar, S. R. & Sharp, J. G., Nov 2011, In : Obesity. 19, 11, p. 2130-2136 7 p.

Research output: Contribution to journalArticle

20 Scopus citations
2010

Human blood and marrow side population stem cell and Stro-1 positive bone marrow stromal cell numbers decline with age, with an increase in quality of surviving stem cells: Correlation with cytokines

Brusnahan, S. K., McGuire, T. R., Jackson, J. D., Lane, J. T., Garvin, K. L., O'Kane, B. J., Berger, A. M., Tuljapurkar, S. R., Kessinger, M. A. & Sharp, J. G., Nov 2010, In : Mechanisms of Ageing and Development. 131, 11-12, p. 718-722 5 p.

Research output: Contribution to journalArticle

35 Scopus citations

Long-term cigarette smoke exposure in a mouse model of ciliated epithelial cell function

Simet, S. M., Sisson, J. H., Pavlik, J. A., DeVasure, J. M., Boyer, C., Liu, X., Kawasaki, S., Sharp, J. G., Rennard, S. I. & Wyatt, T. A., Dec 1 2010, In : American journal of respiratory cell and molecular biology. 43, 6, p. 635-640 6 p.

Research output: Contribution to journalArticle

62 Scopus citations
2009

Non cell-autonomous reprogramming of adult ocular progenitors: Generation of pluripotent stem cells without exogenous transcription factors

Balasubramanian, S., Babai, N., Chaudhuri, A., Qui, F., Bhattacharya, S., Dave, B. J., Parameswaran, S., Carson, S. D., Thoreson, W. B., Sharp, J. G., Rao, M. & Ahmad, I., Dec 2009, In : STEM CELLS. 27, 12, p. 3053-3062 10 p.

Research output: Contribution to journalArticle

36 Scopus citations
2008
1 Scopus citations

Effects of exercise on hematological parameters, circulating side population cells, and cytokines

Wardyn, G. G., Rennard, S. I., Brusnahan, S. K., McGuire, T. R., Carlson, M. L., Smith, L. M., McGranaghan, S. & Sharp, J. G., Feb 2008, In : Experimental Hematology. 36, 2, p. 216-223 8 p.

Research output: Contribution to journalArticle

51 Scopus citations

Mesenchymal Cells of the Lung

Rennard, S. I. & Graham Sharp, J., Jan 11 2008, Chronic Obstructive Pulmonary Disease. Blackwell Publishing Ltd, p. 308-316 9 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2007

Does the number or quality of pluripotent bone marrow stem cells decrease with age?

Garvin, K., Feschuk, C., Sharp, J. G. & Berger, A., Dec 2007, In : Clinical Orthopaedics and Related Research. 465, p. 202-207 6 p.

Research output: Contribution to journalArticle

30 Scopus citations

Human immunodeficiency virus type 1 pathobiology studied in humanized BALB/c-Rag2-/-γc-/- mice

Gorantla, S., Sneller, H., Walters, L., Sharp, J. G., Pirruccello, S. J., West, J. T., Wood, C., Dewhurst, S., Gendelman, H. E. & Poluektova, L., Mar 2007, In : Journal of virology. 81, 6, p. 2700-2712 13 p.

Research output: Contribution to journalArticle

97 Scopus citations
2006

Cytotoxic lymphocytes for the clinic

Barrett, A. J. & Sharp, J. G., May 2006, In : Cytotherapy. 8, 2, p. 93-94 2 p.

Research output: Contribution to journalComment/debate

1 Scopus citations

Novel engineered nanocrystalline ultra-hydrophilic hard ceramic coatings for attachment and growth of bone marrow stromal cells

Namavar, F., Jackson, J. D., Sharp, J. G., Varma, S., Haider, H., Feschuk, C. & Garvin, K. L., Dec 2006, In : MCB Molecular and Cellular Biomechanics. 3, 4, p. 171-172 2 p.

Research output: Contribution to journalArticle

2 Scopus citations

Searching for smart durable coatings to promote bone marrow stromal cell growth while preventing biofilm formation

Namavar, F., Jackson, J. D., Sharp, J. G., Mann, E. E., Bayles, K., Barry, C. L. C., Feschuk, C. A., Varma, S., Haider, H. & Garvin, K. L., 2006, Biofilm-Material Interactions: New Tools, Technologies and Opportunities. Materials Research Society, p. 1-7 7 p. (Materials Research Society Symposium Proceedings; vol. 954).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations
2005

An ex vivo model of hematopoietic stem cell mobilization

Kessinger, A., O'Kane, M. B., Jackson, J. D. & Sharp, J. G., Dec 2005, In : Cytotherapy. 7, 6, p. 463-469 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

Evidence for a qualitative hierarchy within the Hoechst-33342 'side population' (SP) of murine bone marrow cells

Robinson, S. N., Seina, S. M., Gohr, J. C., Kuszynski, C. A. & Sharp, J. G., Apr 2005, In : Bone marrow transplantation. 35, 8, p. 807-818 12 p.

Research output: Contribution to journalArticle

25 Scopus citations

Hematopoietic progenitor cell mobilization by granulocyte colony-stimulating factor and erythropoietin in the absence of matrix metalloproteinase-9

Robinson, S. N., Seina, S. M., Gohr, J. C. & Sharp, J. G., Jun 2005, In : Stem Cells and Development. 14, 3, p. 317-328 12 p.

Research output: Contribution to journalArticle

9 Scopus citations

Promises and pitfalls of stem cell therapy for promotion of bone healing

Sharp, J. G., Murphy, B. O. K., Jackson, J. D., Brusnahan, S. K., Kessinger, A. & Neff, J. R., Jun 2005, In : Clinical Orthopaedics and Related Research. 435, p. 52-61 10 p.

Research output: Contribution to journalArticle

9 Scopus citations
2004

A pilot evaluation of micrometastases for the prediction of outcome in lung cancer

Thompson, A. B., Kessinger, A. & Sharp, J. G., May 2004, In : Chest. 125, 5 SUPPL., p. 156S-157S

Research output: Contribution to journalArticle

2 Scopus citations

Cells derived from the circulation contribute to the repair of lung injury

Abe, S., Boyer, C., Liu, X., Fu, Q. W., Kobayashi, T., Fang, Q., Wang, X., Hashimoto, M., Sharp, J. G. & Rennard, S. I., Dec 1 2004, In : American Journal of Respiratory and Critical Care Medicine. 170, 11, p. 1158-1163 6 p.

Research output: Contribution to journalArticle

133 Scopus citations