• 833 Citations
  • 14 h-Index
1986 …2019

Research output per year

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Research Output

2019
Open Access

Continuous low-intensity ultrasound promotes native-to-native cartilage integration

Sahu, N., Miller, A., Viljoen, H. J. & Subramanian, A., Nov 2019, In : Tissue Engineering - Part A. 25, 21-22, p. 1538-1549 12 p.

Research output: Contribution to journalArticle

Stability analysis of a thin film on a rotating cylinder with low airflow

Newell, H. & Viljoen, H., Mar 1 2019, In : Physics of Fluids. 31, 3, 034106.

Research output: Contribution to journalArticle

2018

Automated Expansion of Primary Human T Cells in Scalable and Cell-Friendly Hydrogel Microtubes for Adoptive Immunotherapy

Lin, H., Li, Q., Wang, O., Rauch, J., Harm, B., Viljoen, H. J., Zhang, C., Van Wyk, E., Zhang, C. & Lei, Y., Aug 8 2018, In : Advanced Healthcare Materials. 7, 15, 1701297.

Research output: Contribution to journalArticle

5 Scopus citations

Scalable Culturing of Primary Human Glioblastoma Tumor-Initiating Cells with a Cell-Friendly Culture System

Li, Q., Lin, H., Rauch, J., Deleyrolle, L. P., Reynolds, B. A., Viljoen, H. J., Zhang, C., Gu, L., Van Wyk, E. & Lei, Y., Dec 1 2018, In : Scientific reports. 8, 1, 3531.

Research output: Contribution to journalArticle

7 Scopus citations
2017

A nonlinear model of cell interaction with an acoustic field

Miller, A. D., Subramanian, A. & Viljoen, H. J., May 3 2017, In : Journal of Biomechanics. 56, p. 83-88 6 p.

Research output: Contribution to journalArticle

2 Scopus citations

Frequency sensitive mechanism in low-intensity ultrasound enhanced bioeffects

Miller, A. D., Chama, A., Louw, T. M., Subramanian, A. & Viljoen, H. J., Aug 2017, In : PloS one. 12, 8, e0181717.

Research output: Contribution to journalArticle

4 Scopus citations
2 Scopus citations
2016

FA mathematical model of recombinase polymerase amplification under continuously stirred conditions

Moody, C., Newell, H. & Viljoen, H., Aug 15 2016, In : Biochemical Engineering Journal. 112, p. 193-201 9 p.

Research output: Contribution to journalArticle

5 Scopus citations

Long-term culture of human mesenchymal stem cell-seeded constructs under ultrasound stimulation: Evaluation of chondrogenesis

Thakurta, S. G., Sahu, N., Miller, A., Budhiraja, G., Akert, L., Viljoen, H. & Subramanian, A., Sep 20 2016, In : Biomedical Physics and Engineering Express. 2, 5, 055016.

Research output: Contribution to journalArticle

1 Scopus citations

Modeling nanoparticle delivery of TB drugs to granulomas

Grobler, A., Perez Sierra, Z. & Viljoen, H. J., Jan 7 2016, In : Journal of Theoretical Biology. 388, p. 85-95 11 p.

Research output: Contribution to journalArticle

5 Scopus citations
2015

Development and evaluation of a rapid multiplex-PCR based system for Mycobacterium tuberculosis diagnosis using sputum samples

Mutingwende, I., Vermeulen, U., Steyn, F., Viljoen, H. & Grobler, A., Sep 1 2015, In : Journal of Microbiological Methods. 116, p. 37-43 7 p.

Research output: Contribution to journalArticle

8 Scopus citations
2 Scopus citations

Theoretical Evaluation of the Acoustic Field in an Ultrasonic Bioreactor

Louw, T. M., Subramanian, A. & Viljoen, H. J., Jun 1 2015, In : Ultrasound in Medicine and Biology. 41, 6, p. 1766-1778 13 p.

Research output: Contribution to journalArticle

5 Scopus citations
2014

A model of isoniazid treatment of tuberculosis

Lemmer, Y., Grobler, A., Moody, C. & Viljoen, H., Dec 21 2014, In : Journal of Theoretical Biology. 363, p. 367-373 7 p.

Research output: Contribution to journalArticle

2 Scopus citations
15 Scopus citations

Mathematical modeling of functionalized-microsphere based assays for rapid DNA detection: From sample preparation to results

Louw, T. M., Gomez-Duarte, O. G., Subramanian, A. & Viljoen, H. J., Jul 15 2014, In : Biochemical Engineering Journal. 88, p. 50-60 11 p.

Research output: Contribution to journalArticle

2013

Mathematical modeling of pathogen trajectory in a patient care environment

Hewlett, A. L., Whitney, S. E., Gibbs, S. G., Smith, P. W. & Viljoen, H. J., Nov 1 2013, In : Infection Control and Hospital Epidemiology. 34, 11, p. 1181-1188 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Mechanotransduction of Ultrasound is Frequency Dependent Below the Cavitation Threshold

Louw, T. M., Budhiraja, G., Viljoen, H. J. & Subramanian, A., Jul 2013, In : Ultrasound in Medicine and Biology. 39, 7, p. 1303-1319 17 p.

Research output: Contribution to journalArticle

29 Scopus citations
2012

A new rapid method for clostridium difficile DNA extraction and detection in stool: Toward point-of-care diagnostic testing

Freifeld, A. G., Simonsen, K. A., Booth, C. S., Zhao, X., Whitney, S. E., Karre, T., Iwen, P. C. & Viljoen, H. J., May 1 2012, In : Journal of Molecular Diagnostics. 14, 3, p. 274-279 6 p.

Research output: Contribution to journalArticle

8 Scopus citations

A state-time epidemiology model of tuberculosis: Importance of re-infection

Viljoen, S., Pienaar, E. & Viljoen, H. J., Feb 1 2012, In : Computational Biology and Chemistry. 36, p. 15-22 8 p.

Research output: Contribution to journalArticle

Evaluation of the real-time protein adsorption kinetics on albumin-binding surfaces by dynamic in situ spectroscopic ellipsometry

Guha Thakurta, S., Viljoen, H. J. & Subramanian, A., Jan 1 2012, In : Thin Solid Films. 520, 6, p. 2200-2207 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

Forced wave motion with internal and boundary damping

Louw, T., Whitney, S., Subramanian, A. & Viljoen, H., Jan 1 2012, In : Journal of Applied Physics. 111, 1, 014702.

Research output: Contribution to journalArticle

7 Scopus citations

Rapid cell lysis and DNA capture in a lysis microreactor

Grobler, A., Levanets, O., Whitney, S., Booth, C. & Viljoen, H., Oct 22 2012, In : Chemical Engineering Science. 81, p. 311-318 8 p.

Research output: Contribution to journalArticle

4 Scopus citations
2011

Experimental validation of a fundamental model for PCR efficiency

Louw, T. M., Booth, C. S., Pienaar, E., TerMaat, J. R., Whitney, S. E. & Viljoen, H. J., Apr 15 2011, In : Chemical Engineering Science. 66, 8, p. 1783-1789 7 p.

Research output: Contribution to journalArticle

2 Scopus citations

Oligonucleotide optimization for DNA synthesis

Louw, T. M., Whitney, S. E., Termaat, J. R., Pienaar, E. & Viljoen, H. J., Jul 1 2011, In : AIChE Journal. 57, 7, p. 1912-1918 7 p.

Research output: Contribution to journalArticle

2 Scopus citations
2010

A model of tuberculosis transmission and intervention strategies in an urban residential area

Pienaar, E., Fluitt, A. M., Whitney, S. E., Freifeld, A. G. & Viljoen, H. J., Apr 1 2010, In : Computational Biology and Chemistry. 34, 2, p. 86-96 11 p.

Research output: Contribution to journalArticle

7 Scopus citations

Efficiency of the polymerase chain reaction

Booth, C. S., Pienaar, E., Termaat, J. R., Whitney, S. E., Louw, T. M. & Viljoen, H. J., Sep 1 2010, In : Chemical Engineering Science. 65, 17, p. 4996-5006 11 p.

Research output: Contribution to journalArticle

10 Scopus citations
2009

A kinetic study of in vitro lysis of mycobacterium smegmatis

Valente, W. J., Pienaar, E., Fast, A., Fluitt, A., Whitney, S. E., Fenton, R. J., Barletta, R. G., Chacon, O. & Viljoen, H. J., May 1 2009, In : Chemical Engineering Science. 64, 9, p. 1944-1952 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

A model of the complex response of Staphylococcus aureus to methicillin

Pienaar, E., Whitney, S. E., Viljoen, H. J. & van Rensburg, N. F. J., Apr 7 2009, In : Journal of Theoretical Biology. 257, 3, p. 438-445 8 p.

Research output: Contribution to journalArticle

4 Scopus citations

The complex response of Staphylococcus aureus to methicillin

Pienaar, E., Whitney, S. E. & Viljoen, H. J., 2009, AIChE Annual Meeting, Conference Proceedings.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2008

A fundamental study of the PCR amplification of GC-rich DNA templates

Mamedov, T. G., Pienaar, E., Whitney, S. E., TerMaat, J. R., Carvill, G., Goliath, R., Subramanian, A. & Viljoen, H. J., Dec 1 2008, In : Computational Biology and Chemistry. 32, 6, p. 452-457 6 p.

Research output: Contribution to journalArticle

75 Scopus citations

The tri-frame model

Pienaar, E. & Viljoen, H. J., Apr 21 2008, In : Journal of Theoretical Biology. 251, 4, p. 616-627 12 p.

Research output: Contribution to journalArticle

8 Scopus citations
2007

Rational de novo gene synthesis by rapid polymerase chain assembly (PCA) and expression of endothelial protein-C and thrombin receptor genes

Mamedov, T. G., Padhye, N. V., Viljoen, H. & Subramanian, A., Sep 30 2007, In : Journal of Biotechnology. 131, 4, p. 379-387 9 p.

Research output: Contribution to journalArticle

11 Scopus citations

Ribosome kinetics and aa-tRNA competition determine rate and fidelity of peptide synthesis

Fluitt, A., Pienaar, E. & Viljoen, H., Oct 1 2007, In : Computational Biology and Chemistry. 31, 5-6, p. 335-346 12 p.

Research output: Contribution to journalArticle

88 Scopus citations

Stochastic events in protein synthesis

Pienaar, E. & Viljoen, H., Dec 1 2007, 2007 AIChE Annual Meeting. (AIChE Annual Meeting, Conference Proceedings).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2006

A quantitative model of error accumulation during PCR amplification

Pienaar, E., Theron, M., Nelson, M. & Viljoen, H. J., Apr 1 2006, In : Computational Biology and Chemistry. 30, 2, p. 102-111 10 p.

Research output: Contribution to journalArticle

26 Scopus citations

CFD analysis of thermal control in a vortex tube based polymerase chain reaction chamber

Raghavan, V., Whitney, S. E., Ebmeier, R. J., Padhye, N. V., Nelson, M., Viljoen, H. J. & Gogos, G., Dec 21 2006, Collection of Technical Papers - 9th AIAA/ASME Joint Thermophysics and Heat Transfer Conference Proceedings. p. 2365-2372 8 p. (Collection of Technical Papers - 9th AIAA/ASME Joint Thermophysics and Heat Transfer Conference Proceedings; vol. 4).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

DNA polymerase chain reaction: A model of error frequencies and extension rates

Griep, M., Whitney, S., Nelson, M. & Viljoen, H., Jan 1 2006, In : AIChE Journal. 52, 1, p. 384-392 9 p.

Research output: Contribution to journalArticle

9 Scopus citations

Kinetics of the DNA polymerase pyrococcus kodakaraensis

Griep, M. A., Kotera, C. A., Nelson, R. M. & Viljoen, H. J., Jun 1 2006, In : Chemical Engineering Science. 61, 12, p. 3885-3892 8 p.

Research output: Contribution to journalArticle

8 Scopus citations

Thermal analysis of the vortex tube based thermocycler for fast DNA amplification: Experimental and two-dimensional numerical results

Raghavan, V., Whitney, S. E., Ebmeier, R. J., Padhye, N. V., Nelson, M., Viljoen, H. J. & Gogos, G., Oct 9 2006, In : Review of Scientific Instruments. 77, 9, 094301.

Research output: Contribution to journalArticle

3 Scopus citations
2005

A macroscopic kinetic model for DNA polymerase elongation and high-fidelity nucleotide selection

Viljoen, S., Griep, M. A., Nelson, M. & Viljoen, H., Apr 1 2005, In : Computational Biology and Chemistry. 29, 2, p. 101-110 10 p.

Research output: Contribution to journalArticle

8 Scopus citations

Critical aspects of oligonucleotide assembly by Pcr

Viljoen, H. J., Dec 1 2005. 1 p.

Research output: Contribution to conferencePaper

Reaction of thermics in a Bridgman anvil. II. Fracture and reaction

Gordopolov, A., Dzenis, O. & Viljoen, H. J., Oct 25 2005, In : Khimicheskaya Fizika. 24, 4, p. 61-66 6 p.

Research output: Contribution to journalArticle

Reactions of thermites in a Bridgman anvil. The pre-explosion phase

Gordopolov, A. & Viljoen, H. J., Oct 25 2005, In : Khimicheskaya Fizika. 24, 3, p. 60-69 10 p.

Research output: Contribution to journalArticle

2004

A study in mechano-chemistry: Pressure induced reactions and non-equilibrium phenomenon

Gordopolov, A. & Viljoen, H. J., 2004, AIChE Annual Meeting, Conference Proceedings. p. 2939-2949 11 p. 281d

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Principles of rapid polymerase chain reaction: Mathematical modeling and experimental verification

Viljoen, H. J., Nelson, R. M. & Whitney, S., 2004, AIChE Annual Meeting, Conference Proceedings. p. 7573-7589 17 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Principles of rapid polymerase chain reactions: Mathematical modeling and experimental verification

Whitney, S. E., Sudhir, A., Nelson, R. M. & Viljoen, H. J., Jul 1 2004, In : Computational Biology and Chemistry. 28, 3, p. 195-209 15 p.

Research output: Contribution to journalArticle

20 Scopus citations

Ranque-hilsch vortex tube thermocycler for DNA amplification

Ebmeier, R., Whitney, S., Alugupally, S., Nelson, M., Padhye, N., Gogos, G. & Viljoen, H. J., Sep 1 2004, In : Instrumentation Science and Technology. 32, 5, p. 567-570 4 p.

Research output: Contribution to journalArticle

3 Scopus citations

Ranque-Hilsch vortex tube thermocycler for fast DMA amplification and real-time optical detection

Ebmeier, R. J., Whitney, S. E., Sarkar, A., Nelson, M., Padhye, N. V., Gogos, G. & Viljoen, H. J., Dec 1 2004, In : Review of Scientific Instruments. 75, 12, p. 5356-5359 4 p.

Research output: Contribution to journalArticle

6 Scopus citations