Iqbal Ahmad, PhD

Professor

  • 3390 Citations
  • 32 h-Index
1990 …2019

Research output per year

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Research Output

  • 3390 Citations
  • 32 h-Index
  • 59 Article
  • 6 Review article
  • 2 Chapter
2019
Open Access
3 Scopus citations

miR-29c regulates neurogliogenesis in the mammalian retina through REST

Xia, X., Teotia, P. & Ahmad, I., Jun 15 2019, In : Developmental Biology. 450, 2, p. 90-100 11 p.

Research output: Contribution to journalArticle

2 Scopus citations

Recapitulating developmental mechanisms for retinal regeneration

Ahmad, I., Teotia, P., Erickson, H. & Xia, X., Jan 1 2019, (Accepted/In press) In : Progress in Retinal and Eye Research. 100824.

Research output: Contribution to journalReview article

2018

Lin28a regulates neurogliogenesis in mammalian retina through the Igf signaling

Xia, X., Teotia, P. & Ahmad, I., Aug 15 2018, In : Developmental Biology. 440, 2, p. 113-128 16 p.

Research output: Contribution to journalArticle

6 Scopus citations
2017

Generation of Functional Human Retinal Ganglion Cells with Target Specificity from Pluripotent Stem Cells by Chemically Defined Recapitulation of Developmental Mechanism

Teotia, P., Chopra, D. A., Dravid, S. M., Van Hook, M. J., Qiu, F., Morrison, J., Rizzino, A. & Ahmad, I., Mar 1 2017, In : STEM CELLS. 35, 3, p. 572-585 14 p.

Research output: Contribution to journalArticle

22 Scopus citations

Modeling Glaucoma: Retinal Ganglion Cells Generated from Induced Pluripotent Stem Cells of Patients with SIX6 Risk Allele Show Developmental Abnormalities

Teotia, P., Van Hook, M. J., Wichman, C. S., Allingham, R. R., Hauser, M. A. & Ahmad, I., Nov 2017, In : STEM CELLS. 35, 11, p. 2239-2252 14 p.

Research output: Contribution to journalArticle

12 Scopus citations
2016

Let-7 microRNA regulates neurogliogenesis in the mammalian retina through Hmga2

Xia, X. & Ahmad, I., Jan 1 2016, In : Developmental Biology. 410, 1, p. 70-85 16 p.

Research output: Contribution to journalArticle

20 Scopus citations

Notch signaling activates stem cell properties of Müller glia through transcriptional regulation and Skp2-mediated degradation of p27Kip1

Del Debbio, C. B., Mir, Q., Parameswaran, S., Mathews, S., Xia, X., Zheng, L., Neville, A. J. & Ahmad, I., Mar 24 2016, In : PloS one. 11, 3, e0152025.

Research output: Contribution to journalArticle

13 Scopus citations

Unlocking the neurogenic potential of mammalian müller glia

Xia, X. & Ahmad, I., Jan 1 2016, In : International Journal of Stem Cells. 9, 2, p. 169-175 7 p.

Research output: Contribution to journalReview article

16 Scopus citations
2015

Continuous non-cell autonomous reprogramming to generate retinal ganglion cells for glaucomatous neuropathy

Parameswaran, S., Dravid, S. M., Teotia, P., Krishnamoorthy, R. R., Qiu, F., Toris, C., Morrison, J. & Ahmad, I., Jun 1 2015, In : STEM CELLS. 33, 6, p. 1743-1758 16 p.

Research output: Contribution to journalArticle

9 Scopus citations

Direct differentiation of adult ocular progenitors into striatal dopaminergic neurons

Ahmad, I., Zhao, X., Parameswaran, S., Destache, C. J., Rodriguez-Sierra, J., Thoreson, W. B., Ahmad, H., Sorrentino, J. & Balasubramanian, S., Jan 1 2015, In : International Journal of Stem Cells. 8, 1, p. 106-114 9 p.

Research output: Contribution to journalArticle

2 Scopus citations
2014

Hmga2 regulates self-renewal of retinal progenitors

Parameswaran, S., Xia, X., Hegde, G. & Ahmad, I., Nov 1 2014, In : Development (Cambridge). 141, 21, p. 4087-4097 11 p.

Research output: Contribution to journalArticle

26 Scopus citations

Rho GTPases control ciliary epithelium cells proliferation and progenitor profile induction in vivo

Del Debbio, C. B., Santos, M. F., Yan, C. Y. I., Ahmad, I. & Hamassaki, D. E., Apr 1 2014, In : Investigative Ophthalmology and Visual Science. 55, 4, p. 2631-2641 11 p.

Research output: Contribution to journalArticle

6 Scopus citations
2013
14 Scopus citations
2012

Noncell autonomous reprogramming to a pluripotent state

Parameswaran, S., Balasubramanian, S. & Ahmad, I., Jan 1 2012, Nuclear Reprogramming and Stem Cells. Humana Press Inc., p. 141-153 13 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Nucleic Acid and Non-Nucleic Acid-Based Reprogramming of Adult Limbal Progenitors to Pluripotency

Parameswaran, S., Balasubramanian, S., Babai, N., DelDebbio, C. B., Harms, D. W., Gurumurthy, C. B., Rao, M. S., Sharp, J. G. & Ahmad, I., Oct 8 2012, In : PloS one. 7, 10, e46734.

Research output: Contribution to journalArticle

8 Scopus citations

Retinal stem cells

Del Debbio, C. B., Parameswaran, S., Das, A. V. & Ahmad, I., Jan 1 2012, Neural Development and Stem Cells: Third Edition. Springer New York, p. 223-244 22 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2011

Concise review: Non-cell autonomous reprogramming: A nucleic acid-free approach to induction of pluripotency

Parameswaran, S., Balasubramanian, S., Rao, M. S. & Ahmad, I., Jul 1 2011, In : STEM CELLS. 29, 7, p. 1013-1020 8 p.

Research output: Contribution to journalReview article

8 Scopus citations

Müller glia: A promising target for therapeutic regeneration

Ahmad, I., del Debbio, C. B., Das, A. V. & Parameswaran, S., Jul 1 2011, In : Investigative Ophthalmology and Visual Science. 52, 8, p. 5758-5764 7 p.

Research output: Contribution to journalArticle

34 Scopus citations

Regulation of ocular angiogenesis by notch signaling: Implications in neovascular age-related macular degeneration

Ahmad, I., Balasubramanian, S., del Debbio, C. B., Parameswaran, S., Katz, A. R., Toris, C. & Fariss, R. N., May 1 2011, In : Investigative Ophthalmology and Visual Science. 52, 6, p. 2868-2878 11 p.

Research output: Contribution to journalArticle

34 Scopus citations
2010

Induced pluripotent stem cells generate both retinal ganglion cells and photoreceptors: Therapeutic implications in degenerative changes in glaucoma and age-related macular degeneration

Parameswaran, S., Balasubramanian, S., Babai, N., Qiu, F., Eudy, J. D., Thoreson, W. B. & Ahmad, I., Apr 1 2010, In : STEM CELLS. 28, 4, p. 695-703 9 p.

Research output: Contribution to journalArticle

91 Scopus citations

Notch and wnt signaling mediated rod photoreceptor regeneration by müller cells in adult mammalian retina

del Debbio, C. B., Balasubramanian, S., Parameswaran, S., Chaudhuri, A., Qiu, F. & Ahmad, I., Oct 19 2010, In : PloS one. 5, 8, e12425.

Research output: Contribution to journalArticle

68 Scopus citations
2009

Non cell-autonomous reprogramming of adult ocular progenitors: Generation of pluripotent stem cells without exogenous transcription factors

Balasubramanian, S., Babai, N., Chaudhuri, A., Qui, F., Bhattacharya, S., Dave, B. J., Parameswaran, S., Carson, S. D., Thoreson, W. B., Sharp, J. G., Rao, M. & Ahmad, I., Dec 1 2009, In : STEM CELLS. 27, 12, p. 3053-3062 10 p.

Research output: Contribution to journalArticle

36 Scopus citations

The canonical Wnt pathway regulates retinal stem cells/progenitors in concert with notch signaling

Das, A. V., Bhattacharya, S., Zhao, X., Hegde, G., Mallya, K., Eudy, J. D. & Ahmad, I., Jan 1 2009, In : Developmental Neuroscience. 30, 6, p. 389-409 21 p.

Research output: Contribution to journalArticle

26 Scopus citations
2008
27 Scopus citations

Derivation of neurons with functional properties from adult limbal epithelium: Implications in autologous cell therapy for photoreceptor degeneration

Zhao, X., Das, A. V., Bhattacharya, S., Thoreson, W. B., Sierra, J. R., Mallya, K. B. & Ahmad, I., Apr 1 2008, In : STEM CELLS. 26, 4, p. 939-949 11 p.

Research output: Contribution to journalArticle

27 Scopus citations
2007

Characterization of early retinal progenitor microenvironment: Presence of activities selective for the differentiation of retinal ganglion cells and maintenance of progenitors

Hegde, G. V., James, J., Das, A. V., Zhao, X., Bhattacharya, S. & Ahmad, I., Mar 1 2007, In : Experimental Eye Research. 84, 3, p. 577-590 14 p.

Research output: Contribution to journalArticle

12 Scopus citations

Maintenance of retinal stem cells by Abcg2 is regulated by notch signaling

Bhattacharya, S., Das, A., Mallya, K. & Ahmad, I., Aug 1 2007, In : Journal of cell science. 120, 15, p. 2652-2662 11 p.

Research output: Contribution to journalArticle

60 Scopus citations

SWI/SNF chromatin remodeling ATPase Brm regulates the differentiation of early retinal stem cells/progenitors by influencing Brn3b expression and Notch signaling

Das, A. V., James, J., Bhattacharya, S., Imbalzano, A. N., Antony, M. L., Hegde, G., Zhao, X., Mallya, K., Ahmad, F., Knudsen, E. & Ahmad, I., Nov 30 2007, In : Journal of Biological Chemistry. 282, 48, p. 35187-35201 15 p.

Research output: Contribution to journalArticle

30 Scopus citations
2006

Differentiation of embryonic stem cells to retinal cells in vitro.

Zhao, X., Liu, J. & Ahmad, I., 2006, In : Methods in molecular biology (Clifton, N.J.). 330, p. 401-416 16 p.

Research output: Contribution to journalArticle

16 Scopus citations

Neural stem cell properties of Müller glia in the mammalian retina: Regulation by Notch and Wnt signaling

Das, A. V., Mallya, K. B., Zhao, X., Ahmad, F., Bhattacharya, S., Thoreson, W. B., Hegde, G. V. & Ahmad, I., Nov 1 2006, In : Developmental Biology. 299, 1, p. 283-302 20 p.

Research output: Contribution to journalArticle

237 Scopus citations

Neural stem cells in the adult ciliary epithelium express GFAP and are regulated by Wnt signaling

Das, A. V., Zhao, X., James, J., Kim, M., Cowan, K. H. & Ahmad, I., Jan 13 2006, In : Biochemical and Biophysical Research Communications. 339, 2, p. 708-716 9 p.

Research output: Contribution to journalArticle

34 Scopus citations
2005

Growth factor-responsive progenitors in the postnatal mammalian retina

Zhao, X., Das, A. V., Soto-Leon, F. & Ahmad, I., Feb 1 2005, In : Developmental Dynamics. 232, 2, p. 349-358 10 p.

Research output: Contribution to journalArticle

41 Scopus citations

Membrane properties of retinal stem cells/progenitors

Das, A. V., Edakkot, S., Thoreson, W. B., James, J., Bhattacharya, S. & Ahmad, I., Nov 1 2005, In : Progress in Retinal and Eye Research. 24, 6, p. 663-681 19 p.

Research output: Contribution to journalReview article

16 Scopus citations

Retinal properties and potential of the adult mammalian ciliary epithelium stem cells

Das, A. V., James, J., Rahnenführer, J., Thoreson, W. B., Bhattacharya, S., Zhao, X. & Ahmad, I., Jun 2005, In : Vision research. 45, 13, p. 1653-1666 14 p.

Research output: Contribution to journalArticle

63 Scopus citations

Stem cell therapy for retinal degeneration: Retinal neurons from heterologous sources

Das, A. M., Zhao, X. & Ahmad, I., Jan 1 2005, In : Seminars in Ophthalmology. 20, 1, p. 3-10 8 p.

Research output: Contribution to journalReview article

17 Scopus citations
2004
54 Scopus citations

Identification of c-Kit receptor as a regulator of adult neural stem cells in the mammalian eye: Interactions with Notch signaling

Das, A. V., James, J., Zhao, X., Rahnenführer, J. & Ahmad, I., Sep 1 2004, In : Developmental Biology. 273, 1, p. 87-105 19 p.

Research output: Contribution to journalArticle

55 Scopus citations

Involvement of Ath3 in CNTF-mediated differentiation of the late retinal progenitors

Bhattacharya, S., Dooley, C., Soto, F., Madson, J., Das, A. V. & Ahmad, I., Sep 1 2004, In : Molecular and Cellular Neuroscience. 27, 1, p. 32-43 12 p.

Research output: Contribution to journalArticle

17 Scopus citations

Neural stem cells in the mammalian eye: Types and regulation

Ahmad, I., Das, A. V., James, J., Bhattacharya, S. & Zhao, X., Feb 2004, In : Seminars in Cell and Developmental Biology. 15, 1, p. 53-62 10 p.

Research output: Contribution to journalArticle

91 Scopus citations
2003

Direct identification and enrichment of retinal stem cells/progenitors by hoechst dye efflux assay

Bhattacharya, S., Jackson, J. D., Das, A. V., Thoreson, W. B., Kuszynski, C., James, J., Joshi, S. & Ahmad, I., Jun 1 2003, In : Investigative Ophthalmology and Visual Science. 44, 6, p. 2764-2773 10 p.

Research output: Contribution to journalArticle

91 Scopus citations

In vitro generation of early-born neurons from late retinal progenitors

James, J., Das, A. V., Bhattacharya, S., Chacko, D. M., Zhao, X. & Ahmad, I., Sep 10 2003, In : Journal of Neuroscience. 23, 23, p. 8193-8203 11 p.

Research output: Contribution to journalArticle

56 Scopus citations

Involvement of numb in vertebrate retinal development: Evidence for multiple roles of numb in neural differentiation and maturation

Dooley, C. M., James, J., McGlade, C. J. & Ahmad, I., Feb 2 2003, In : Journal of Neurobiology. 54, 2, p. 313-325 13 p.

Research output: Contribution to journalArticle

31 Scopus citations

Transplantation of ocular stem cells: The role of injury in incorporation and differentiation of grafted cells in the retina

Chacko, D. M., Das, A. V., Zhao, X., James, J., Bhattacharya, S. & Ahmad, I., Apr 2003, In : Vision research. 43, 8, p. 937-946 10 p.

Research output: Contribution to journalArticle

106 Scopus citations
2002

Adult corneal limbal epithelium: A model for studying neural potential of non-neural stem cells/progenitors

Zhao, X., Das, A. V., Thoreson, W. B., James, J., Wattnem, T. E., Rodriguez-Sierra, J. & Ahmad, I., Jan 1 2002, In : Developmental Biology. 250, 2, p. 317-331 15 p.

Research output: Contribution to journalArticle

81 Scopus citations

Differentiation of embryonic stem cells into retinal neurons

Zhao, X., Liu, J. & Ahmad, I., Nov 6 2002, In : Biochemical and Biophysical Research Communications. 297, 2, p. 177-184 8 p.

Research output: Contribution to journalArticle

97 Scopus citations

Epidermal Growth Factor (EGT) induces a phenotypic switch of a human glioblastoma cell line to neurospheres

Bargar, T., El-Refaey, H., Ahmad, I., Ebadi, M. & Rodriguez-Sierra, J., Nov 20 2002, In : Microscopy and Microanalysis. 8, SUPPL. 2, p. 1012-1013 2 p.

Research output: Contribution to journalArticle

Identification of the mouse and rat orthologs of the gene mutated in Usher syndrome type IIA and the cellular source of USH2A mRNA in retina, a target tissue of the disease

Huang, D., Eudy, J. D., Uzvolgyi, E., Davis, J. R., Talmadge, C. B., Pretto, D., Weston, M. D., Lehman, J. E., Zhou, M., Seemayer, T. A., Ahmad, I., Kimberling, W. J. & Sumegi, J., Jan 1 2002, In : Genomics. 80, 2, p. 195-203 9 p.

Research output: Contribution to journalArticle

12 Scopus citations
2001

Stem cells: New opportunities to treat eye diseases

Ahmad, I., Nov 17 2001, In : Investigative Ophthalmology and Visual Science. 42, 12, p. 2743-2748 6 p.

Research output: Contribution to journalReview article

48 Scopus citations
2000

Identification of neural progenitors in the adult mammalian eye

Ahmad, I., Tang, L. & Pham, H., Apr 13 2000, In : Biochemical and Biophysical Research Communications. 270, 2, p. 517-521 5 p.

Research output: Contribution to journalArticle

364 Scopus citations