Iraklis I Pipinos, MD

  • 3620 Citations
  • 33 h-Index
1994 …2020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

2020
4 Scopus citations

Collateral Development and Arteriogenesis in Hindlimbs of Swine After Ligation of Arterial Inflow

Gao, Y., Aravind, S., Patel, N. S., Fuglestad, M. A., Ungar, J. S., Mietus, C. J., Li, S., Casale, G. P., Pipinos, I. I. & Carlson, M. A., May 2020, In : Journal of Surgical Research. 249, p. 168-179 12 p.

Research output: Contribution to journalArticle

Reply

Fuglestad, M., Hernandez, H., Gao, Y., Ybay, H., Schieber, M., Brunette, K. E., Myers, S., Casale, G. & Pipinos, I., Mar 2020, In : Journal of vascular surgery. 71, 3, p. 1072-1073 2 p.

Research output: Contribution to journalLetter

Open Access

Supervised walking exercise therapy improves gait biomechanics in patients with peripheral artery disease

Schieber, M. N., Pipinos, I. I., Johanning, J. M., Casale, G. P., Williams, M. A., DeSpiegelaere, H. K., Senderling, B. & Myers, S. A., Feb 2020, In : Journal of vascular surgery. 71, 2, p. 575-583 9 p.

Research output: Contribution to journalArticle

1 Scopus citations

The nitric oxide system in peripheral artery disease: Connection with oxidative stress and biopterins

Ismaeel, A., Papoutsi, E., Miserlis, D., Lavado, R., Haynatzki, G., Casale, G. P., Bohannon, W. T., Smith, R. S., Eidson, J. L., Brumberg, R., Hayson, A., Kirk, J. S., Castro, C., Sawicki, I., Konstantinou, C., Brewster, L. P., Pipinos, I. I. & Koutakis, P., Jul 2020, In : Antioxidants. 9, 7, p. 1-16 16 p., 590.

Research output: Contribution to journalArticle

Open Access
2019
1 Scopus citations

Novel open technique for repair of endograft migration

Gao, Y., Miserlis, D., Garg, N. & Pipinos, I., Jun 2019, In : Journal of Vascular Surgery Cases and Innovative Techniques. 5, 2, p. 88-90 3 p.

Research output: Contribution to journalArticle

Open Access

Quantification of Daily Physical Activity and Sedentary Behavior of Claudicating Patients

Hernandez, H., Myers, S. A., Schieber, M., Ha, D. M., Baker, S., Koutakis, P., Kim, K. S., Mietus, C., Casale, G. P. & Pipinos, I. I., Feb 2019, In : Annals of Vascular Surgery. 55, p. 112-121 10 p.

Research output: Contribution to journalArticle

2 Scopus citations
Open Access
2018

Chloroquine improves the response to ischemic muscle injury and increases HMGB1 after arterial ligation

Xu, J., Cui, X., Li, J., Koutakis, P., Pipinos, I., Tzeng, E., Chen, A. & Sachdev, U., Mar 2018, In : Journal of vascular surgery. 67, 3, p. 910-921 12 p.

Research output: Contribution to journalArticle

5 Scopus citations

Correction: Premature aortic smooth muscle cell differentiation contributes to matrix dysregulation in Marfan Syndrome(PLoS ONE (2017) 12:10 (e0186603) DOI: 10.1371/journal.pone.0186603)

Dale, M., Fitzgerald, M. P., Liu, Z., Meisinger, T., Karpisek, A., Purcell, L. N., Carson, J. S., Harding, P., Lang, H., Koutakis, P., Suh, M., Batra, R., Mietus, C. J., Casale, G. P., Pipinos, I. I., Timothy Baxter, B. & Xiong, W., Jul 2018, In : PloS one. 13, 7, e0200985.

Research output: Contribution to journalComment/debate

Fluid administration rate for uncontrolled intraabdominal hemorrhage in swine

Yanala, U. R., Johanning, J. M., Pipinos, I. I., High, R. R., Larsen, G., Velander, W. H. & Carlson, M. A., Nov 2018, In : PloS one. 13, 11, e0207708.

Research output: Contribution to journalArticle

IL-1β (Interleukin-1β) and TNF-α (Tumor Necrosis Factor-α) Impact Abdominal Aortic Aneurysm Formation by Differential Effects on Macrophage Polarization

Batra, R., Suh, M. K., Carson, J. S., Dale, M. A., Meisinger, T. M., Fitzgerald, M., Opperman, P. J., Luo, J., Pipinos, I. I., Xiong, W. & Baxter, B. T., Feb 1 2018, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 38, 2, p. 457-463 7 p.

Research output: Contribution to journalArticle

15 Scopus citations

In vitro measurements of hemodynamic forces and their effects on endothelial cell mechanics at the sub-cellular level

Lambert, L. M., Pipinos, I. I., Baxter, B. T., Chatzizisis, Y. S., Ryu, S. J., Leighton, R. I. & Wei, T., Nov 1 2018, In : Biomicrofluidics. 12, 6, 064101.

Research output: Contribution to journalArticle

1 Scopus citations

Passive Wearable Skin Patch Sensor Measures Limb Hemodynamics Based on Electromagnetic Resonance

Cluff, K., Becker, R., Jayakumar, B., Han, K., Condon, E., Dudley, K., Szatkowski, G., Pipinos, I. I., Amick, R. Z. & Patterson, J., Apr 2018, In : IEEE Transactions on Biomedical Engineering. 65, 4, p. 847-856 10 p.

Research output: Contribution to journalArticle

8 Scopus citations
2017

Analysis of ischemic muscle in patients with peripheral artery disease using X-ray spectroscopy

Becker, R. A., Cluff, K., Duraisamy, N., Casale, G. P. & Pipinos, I. I., Dec 2017, In : Journal of Surgical Research. 220, p. 79-87 9 p.

Research output: Contribution to journalArticle

1 Scopus citations

An endovascular model of ischemic myopathy from peripheral arterial disease

Long, C. A., Timmins, L. H., Koutakis, P., Goodchild, T. T., Lefer, D. J., Pipinos, I. I., Casale, G. P. & Brewster, L. P., Sep 2017, In : Journal of vascular surgery. 66, 3, p. 891-901 11 p.

Research output: Contribution to journalArticle

6 Scopus citations

Contained Rupture of an Abdominal Aortic Aneurysm with Extensive Vertebral Body and Retroperitoneal Space Destruction

Walker, S. T., Pipinos, I. I., Johanning, J. M. & Vargo, C. J., Sep 1 2017, In : Journal of Computer Assisted Tomography. 41, 5, p. 839-842 4 p.

Research output: Contribution to journalArticle

1 Scopus citations

Dexamethasone promotes long-term functional recovery of neuromuscular junction in a murine model of tourniquet-induced ischaemia–reperfusion

Zhang, D., Wang, D., Pipinos, I. I., Muelleman, R. L. & Li, Y. L., Feb 1 2017, In : Acta Physiologica. 219, 2, p. 453-464 12 p.

Research output: Contribution to journalArticle

7 Scopus citations

Gait deficiencies associated with peripheral artery disease are different than chronic obstructive pulmonary disease

McCamley, J. D., Pisciotta, E. J., Yentes, J. M., Wurdeman, S. R., Rennard, S. I., Pipinos, I. I., Johanning, J. M. & Myers, S. A., Sep 2017, In : Gait and Posture. 57, p. 258-264 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

Meta-analysis of individual-patient data from EVAR-1, DREAM, OVER and ACE trials comparing outcomes of endovascular or open repair for abdominal aortic aneurysm over 5 years

the EVAR-1, DREAM, OVER and ACE Trialists, Feb 1 2017, In : British Journal of Surgery. 104, 3, p. 166-178 13 p.

Research output: Contribution to journalReview article

125 Scopus citations

Muscle strength and control characteristics are altered by peripheral artery disease

Schieber, M. N., Hasenkamp, R. M., Pipinos, I. I., Johanning, J. M., Stergiou, N., DeSpiegelaere, H. K., Chien, J. H. & Myers, S. A., Jul 2017, In : Journal of vascular surgery. 66, 1, p. 178-186.e12

Research output: Contribution to journalArticle

11 Scopus citations

Optical probing of gastrocnemius in patients with peripheral artery disease characterizes myopathic biochemical alterations and correlates with stage of disease

Becker, R. A., Cluff, K., Duraisamy, N., Mehraein, H., Farhoud, H., Collins, T., Casale, G. P., Pipinos, I. I. & Subbiah, J., Mar 1 2017, In : Physiological Reports. 5, 5, e13161.

Research output: Contribution to journalArticle

3 Scopus citations

Premature aortic smooth muscle cell differentiation contributes to matrix dysregulation in Marfan Syndrome

Dale, M., Fitzgerald, M. P., Liu, Z., Meisinger, T., Karpisek, A., Purcell, L. N., Carson, J. S., Harding, P., Lang, H., Koutakis, P., Batra, R., Mietus, C. J., Casale, G., Pipinos, I., Baxter, B. T. & Xiong, W., Oct 2017, In : PloS one. 12, 10, e0186603.

Research output: Contribution to journalArticle

16 Scopus citations

Thoracofemoral bypass graft for aortoiliac occlusive disease

Pipinos, I. & Hernandez, H., Jan 1 2017, Endovascular and Open Vascular Reconstruction: A Practical Approach. CRC Press, p. 307-311 5 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2016

Gait kinematics and kinetics are affected more by peripheral arterial disease than by age

Myers, S. A., Applequist, B. C., Huisinga, J. M., Pipinos, I. I. & Johanning, J. M., 2016, In : Journal of Rehabilitation Research and Development. 53, 2, p. 229-238 10 p.

Research output: Contribution to journalArticle

5 Scopus citations

Long-term cost-effectiveness in the veterans affairs open vs endovascular repair study of aortic abdominal aneurysm: A randomized clinical trial

Lederle, F. A., Stroupe, K. T., Kyriakides, T. C., Ge, L., Freischlag, J. A., Ketteler, E. R., Kingsley, D. D., Marek, J. M., Massen, R. J., Matteson, B. D., David Pitcher, J., Langsfeld, M., Corson, J. D., Goff, J. M., Kasirajan, K., Paap, C., Robertson, D. C., Salam, A., Veeraswamy, R., Milner, R. & 286 others, Kasirajan, K., Guidot, J., Lal, B. K., Busuttil, S. J., Lilly, M. P., Braganza, M., Ellis, K., Patterson, M. A., Jordan, W. D., Whitley, D., Taylor, S., Passman, M., Kerns, D., Inman, C., Poirier, J., Ebaugh, J., Raffetto, J., Chew, D., Lathi, S., Owens, C., Hickson, K., Dosluoglu, H. H., Eschberger, K., Kibbe, M. R., Baraniewski, H. M., Matsumura, J., Endo, M., Busman, A., Meadows, W., Evans, M., Giglia, J. S., El Sayed, H., Reed, A. B., Ruf, M., Ross, S., Jean-Claude, J. M., Pinault, G., Kang, P., White, N., Eiseman, M., Jones, R., Timaran, C. H., Gregory Modrall, J., Burress Welborn, M., Lopez, J., Nguyen, T., Chacko, J. K. Y., Granke, K., Vouyouka, A. G., Olgren, E., Chand, P., Allende, B., Ranella, M., Yales, C., Whitehill, T. A., Krupski, W. C., Nehler, M. R., Johnson, S. P., Jones, D. N., Strecker, P., Bhola, M. A., Shortell, C. K., Gray, J. L., Lawson, J. H., McCann, R., Sebastian, M. W., Tetterton, J. K., Blackwell, C., Prinzo, P. A., Lee, N., Padberg, F. T., Cerveira, J. J., Zickler, R. W., Hauck, K. A., Berceli, S. A., Anthony Lee, W., Keith Ozaki, C., Nelson, P. R., Irwin, A. S., Baum, R., Aulivola, B., Rodriguez, H., Littooy, F. N., Greisler, H., O'Sullivan, M. T., Kougias, P., Lin, P. H., Bush, R. L., Guinn, G., Bechara, C., Cagiannos, C., Pisimisis, G., Barshes, N., Pillack, S., Guillory, B., Cikrit, D., Lalka, S. G., Lemmon, G., Nachreiner, R., Rusomaroff, M., O'Brien, E., Cullen, J. J., Hoballah, J., John Sharp, W., McCandless, J. L., Beach, V., Minion, D., Schwarcz, T. H., Kimbrough, J., Ashe, L., Rockich, A., Warner-Carpenter, J., Moursi, M., Eidt, J. F., Brock, S., Bianchi, C., Bishop, V., Gordon, I. L., Fujitani, R., Kubaska, S. M., Behdad, M., Azadegan, R., Maagas, C., Zalecki, K., Hoch, J. R., Carr, S. C., Acher, C., Schwarze, M., Tefera, G., Mell, M., Dunlap, B., Rieder, J., Stuart, J. M., Weiman, D. S., Abul-Khoudoud, O., Edward Garrett, H., Walsh, S. M., Wilson, K. L., Seabrook, G. R., Cambria, R. A., Brown, K. R., Lewis, B. D., Framberg, S., Kallio, C., Barke, R. A., Santilli, S. M., D'Audiffret, A. C., Oberle, N., Proebstle, C., Johnson, L. L., Jacobowitz, G. R., Cayne, N., Rockman, C., Adelman, M., Gagne, P., Nalbandian, M., Caropolo, L. J., Pipinos, I. I., Johanning, J. M., Lynch, T., De Spiegelaere, H., Purviance, G., Zhou, W., Dalman, R., Lee, J. T., Safadi, B., Coogan, S. M., Wren, S. M., Bahmani, D. D., Maples, D., Thunen, S., Golden, M. A., Mitchell, M. E., Fairman, R., Reinhardt, S., Wilson, M. A., Tzeng, E., Muluk, S., Peterson, N. M., Foster, M., Edwards, J., Moneta, G. L., Landry, G., Taylor, L., Yeager, R., Cannady, E., Treiman, G., Hatton-Ward, S., Salabsky, B., Kansal, N., Owens, E., Estes, M., Forbes, B. A., Sobotta, C., Rapp, J. H., Reilly, L. M., Perez, S. L., Yan, K., Sarkar, R., Dwyer, S. S., Chong, K., Kohler, T. R., Hatsukami, T. S., Glickerman, D. G., Sobel, M., Burdick, T. S., Pedersen, K., Cleary, P., Back, M., Bandyk, D., Johnson, B., Shames, M., Reinhard, R. L., Thomas, S. C., Hunter, G. C., Leon, L. R., Westerband, A., Guerra, R. J., Riveros, M., Mills, J. L., Hughes, J. D., Escalante, A. M., Psalms, S. B., Day, N. N., Macsata, R., Sidawy, A., Weiswasser, J., Arora, S., Jasper, B. J., Dardik, A., Gahtan, V., Muhs, B. E., Sumpio, B. E., Gusberg, R. J., Spector, M., Pollak, J., Aruny, J., Lynne Kelly, E., Wong, J., Vasilas, P., Joncas, C., Gelabert, H. A., De Virgillio, C., Rigberg, D. A., Cole, L., Latts, E., Swanson, K. M., Johnson, G. R., Guarino, P., Peduzzi, P., Antonelli, M., Cushing, C., Davis, E., Durant, L., Joyner, S., Kossack, A., Le Gwin, M., McBride, V., O'Connor, T., Poulton, J., Stratton, S., Zellner, S., Snodgrass, A. J., Thornton, J., Haakenson, C. M., Jonk, Y., Hallett, J. W., Hertzer, N., Towne, J., Katz, D. A., Karrison, T., Matts, J. P., Marottoli, R., Kasl, S., Mehta, R., Feldman, R., Farrell, W., Allore, H., Perry, E., Niederman, J., Randall, S. F., Zeman, R. M., Beckwith, D., O'Leary, T. J., Huang, G. D. & Bader, M., Dec 1 2016, In : JAMA Surgery. 151, 12, p. 1139-1144 6 p.

Research output: Contribution to journalArticle

13 Scopus citations

Outcomes of aortic surgery for abdominal aortic graft infections

Gupta, P. K., Ramanan, B., Grossman, L., Gupta, H., Fang, X., MacTaggart, J. N., Lynch, T. G., Baxter, B. T. & Pipinos, I. I., 2016, In : Vascular and Endovascular Surgery. 50, 4, p. 256-260 5 p.

Research output: Contribution to journalArticle

2 Scopus citations

Transforming growth factor-beta 1 produced by vascular smooth muscle cells predicts fibrosis in the gastrocnemius of patients with peripheral artery disease

Ha, D. M., Carpenter, L. C., Koutakis, P., Swanson, S. A., Zhu, Z., Hanna, M., DeSpiegelaere, H. K., Pipinos, I. I. & Casale, G. P., Feb 4 2016, In : Journal of Translational Medicine. 14, 1, 39.

Research output: Contribution to journalArticle

19 Scopus citations
2015
25 Scopus citations

Abnormal myofiber morphology and limb dysfunction in claudication

Koutakis, P., Myers, S. A., Cluff, K., Ha, D. M., Haynatzki, G., McComb, R. D., Uchida, K., Miserlis, D., Papoutsi, E., Johanning, J. M., Casale, G. P. & Pipinos, I. I., Jun 1 2015, In : Journal of Surgical Research. 196, 1, p. 172-179 8 p.

Research output: Contribution to journalArticle

19 Scopus citations

Age and disease-related geometric and structural remodeling of the carotid artery

Kamenskiy, A. V., Pipinos, I. I., Carson, J. S., Mactaggart, J. N. & Baxter, B. T., Dec 2015, In : Journal of vascular surgery. 62, 6, p. 1521-1528 8 p.

Research output: Contribution to journalArticle

28 Scopus citations

Effects of age on the physiological and mechanical characteristics of human femoropopliteal arteries

Kamenskiy, A. V., Pipinos, I. I., Dzenis, Y. A., Phillips, N. Y., Desyatova, A. S., Kitson, J., Bowen, R. & MacTaggart, J. N., 2015, In : Acta Biomaterialia. 11, 1, p. 304-313 10 p.

Research output: Contribution to journalArticle

30 Scopus citations

Increased minimum toe clearance variability in patients with peripheral arterial disease

Rand, T. J., Wurdeman, S. R., Johanning, J. M., Pipinos, I. I. & Myers, S. A., Dec 1 2015, In : Medical Engineering and Physics. 37, 12, p. 1141-1145 5 p.

Research output: Contribution to journalArticle

Patient demographics and cardiovascular risk factors differentially influence geometric remodeling of the aorta compared with the peripheral arteries

Kamenskiy, A., Miserlis, D., Adamson, P., Adamson, M., Knowles, T., Neme, J., Koutakis, P., Phillips, N., Pipinos, I. & MacTaggart, J., Dec 2015, In : Surgery (United States). 158, 6, p. 1617-1627 11 p.

Research output: Contribution to journalArticle

12 Scopus citations

Preoperative frailty risk analysis index to stratify patients undergoing carotid endarterectomy

Melin, A. A., Schmid, K. K., Lynch, T. G., Pipinos, I. I., Kappes, S., Longo, G. M., Gupta, P. K. & Johanning, J. M., Mar 1 2015, In : Journal of vascular surgery. 61, 3, p. 683-689 7 p.

Research output: Contribution to journalArticle

46 Scopus citations

Protein concentration and mitochondrial content in the gastrocnemius predicts mortality rates in patients with peripheral arterial disease

Thompson, J. R., Swanson, S. A., Haynatzki, G., Koutakis, P., Johanning, J. M., Reppert, P. R., Papoutsi, E., Miserlis, D., Zhu, Z., Casale, G. P. & Pipinos, I. I., 2015, In : Annals of surgery. 261, 3, p. 605-610 6 p.

Research output: Contribution to journalArticle

17 Scopus citations

Spatiotemporal Changes Posttreatment in Peripheral Arterial Disease

Myers, S. A., Huben, N. B., Yentes, J. M., McCamley, J. D., Lyden, E. R., Pipinos, I. I. & Johanning, J. M., 2015, In : Rehabilitation Research and Practice. 2015, 124023.

Research output: Contribution to journalReview article

1 Scopus citations
5 Scopus citations

Therapeutic potential of sustained-release sodium nitrite for critical limb ischemia in the setting of metabolic syndrome

Polhemus, D. J., Bradley, J. M., Islam, K. N., Brewster, L. P., Calvert, J. W., Tao, Y. X., Chang, C. C., Pipinos, I. I., Goodchild, T. T. & Lefer, D. J., Jul 6 2015, In : American Journal of Physiology - Heart and Circulatory Physiology. 309, 1, p. H82-H92

Research output: Contribution to journalArticle

9 Scopus citations
2014

A switch in the source of ATP production and a loss in capacity to perform glycolysis are hallmarks of hepatocyte failure in advance liver disease

Nishikawa, T., Bellance, N., Damm, A., Bing, H., Zhu, Z., Handa, K., Yovchev, M. I., Sehgal, V., Moss, T. J., Oertel, M., Ram, P. T., Pipinos, I. I., Soto-Gutierrez, A., Fox, I. J. & Nagrath, D., Jun 2014, In : Journal of Hepatology. 60, 6, p. 1203-1211 9 p.

Research output: Contribution to journalArticle

48 Scopus citations

A totally recombinant human fibrin sealant

Carlson, M. A., Calcaterra, J., Johanning, J. M., Pipinos, I. I., Cordes, C. M. & Velander, W. H., Mar 2014, In : Journal of Surgical Research. 187, 1, p. 334-342 9 p.

Research output: Contribution to journalArticle

16 Scopus citations

Biaxial mechanical properties of the human thoracic and abdominal aorta, common carotid, subclavian, renal and common iliac arteries

Kamenskiy, A. V., Dzenis, Y. A., Kazmi, S. A. J., Pemberton, M. A., Pipinos, I. I., Phillips, N. Y., Herber, K., Woodford, T., Bowen, R. E., Lomneth, C. S. & MacTaggart, J. N., Oct 7 2014, In : Biomechanics and Modeling in Mechanobiology. 13, 6, p. 1341-1359 19 p.

Research output: Contribution to journalArticle

39 Scopus citations
3 Scopus citations

Oxidative damage in the gastrocnemius of patients with peripheral artery disease is myofiber type selective

Koutakis, P., Weiss, D. J., Miserlis, D., Shostrom, V. K., Papoutsi, E., Ha, D. M., Carpenter, L. A., McComb, R. D., Casale, G. P. & Pipinos, I. I., 2014, In : Redox Biology. 2, 1, p. 921-928 8 p.

Research output: Contribution to journalArticle

33 Scopus citations

Passive biaxial mechanical properties and in vivo axial pre-stretch of the diseased human femoropopliteal and tibial arteries

Kamenskiy, A. V., Pipinos, I. I., Dzenis, Y. A., Lomneth, C. S., Kazmi, S. A. J., Phillips, N. Y. & MacTaggart, J. N., Mar 2014, In : Acta Biomaterialia. 10, 3, p. 1301-1313 13 p.

Research output: Contribution to journalArticle

32 Scopus citations

Surface-enhanced Raman spectral biomarkers correlate with Ankle Brachial Index and characterize leg muscle biochemical composition of patients with peripheral arterial disease

Cluff, K., Kelly, A. M., Koutakis, P., He, X. N., Huang, X., Lu, Y. F., Pipinos, I. I., Casale, G. P. & Subbiah, J., 2014, In : Physiological Reports. 2, 9, e12148.

Research output: Contribution to journalArticle

8 Scopus citations

Three-dimensional bending, torsion and axial compression of the femoropopliteal artery during limb flexion

MacTaggart, J. N., Phillips, N. Y., Lomneth, C. S., Pipinos, I. I., Bowen, R., Timothy Baxter, B., Johanning, J., Matthew Longo, G., Desyatova, A. S., Moulton, M. J., Dzenis, Y. A. & Kamenskiy, A. V., Jul 18 2014, In : Journal of Biomechanics. 47, 10, p. 2249-2256 8 p.

Research output: Contribution to journalArticle

35 Scopus citations
2013
12 Scopus citations