Irving H Zucker, PhD

  • 7775 Citations
  • 51 h-Index
1973 …2020

Research output per year

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Research Output

2004
26 Scopus citations

Exercise training and sympathetic regulation in experimental heart failure

Zucker, I. H., Patel, K. P., Schultz, H. D., Li, Y. F., Wang, W. & Pliquett, R. U., Jul 2004, In : Exercise and Sport Sciences Reviews. 32, 3, p. 107-111 5 p.

Research output: Contribution to journalReview article

53 Scopus citations

Superoxide mediates sympathoexcitation in heart failure: Roles of angiotensin II and NAD(P)H oxidase

Gao, L., Wang, W., Li, Y. L., Schultz, H. D., Liu, D., Cornish, K. G. & Zucker, I. H., Oct 29 2004, In : Circulation Research. 95, 9, p. 937-944 8 p.

Research output: Contribution to journalArticle

205 Scopus citations

The origin of sympathetic outflow in heart failure: The roles of angiotensin II and nitric oxide

Zucker, I. H., Schultz, H. D., Li, Y. F., Wang, Y., Wang, W. & Patel, K. P., 2004, In : Progress in Biophysics and Molecular Biology. 84, 2-3, p. 217-232 16 p.

Research output: Contribution to journalReview article

112 Scopus citations
2005

Augmented input from cardiac sympathetic afferents inhibits baroreflex in rats with heart failure

Gao, L., Schultz, H. D., Patel, K. P., Zucker, I. H. & Wang, W., Jun 2005, In : Hypertension. 45, 6, p. 1173-1181 9 p.

Research output: Contribution to journalArticle

59 Scopus citations

Effects of angiotensin II on autonomic components of nasopharyngeal stimulation in male conscious rabbits

Mousa, T. M., Gao, L., Cornish, K. G. & Zucker, I. H., May 2005, In : Journal of Applied Physiology. 98, 5, p. 1607-1611 5 p.

Research output: Contribution to journalArticle

8 Scopus citations
35 Scopus citations
94 Scopus citations

Gene transfer of neuronal nitric oxide synthase to carotid body reverses enhanced chemoreceptor function in heart failure rabbits

Li, Y. L., Li, Y. F., Liu, D., Cornish, K. G., Patel, K. P., Zucker, I. H., Channon, K. M. & Schultz, H. D., Aug 5 2005, In : Circulation Research. 97, 3, p. 260-267 8 p.

Research output: Contribution to journalArticle

58 Scopus citations

Manipulation of neuronal nitric oxide synthase within the paraventricular nucleus using adenovirus and antisense technology.

Li, Y. F., Wang, Y., Channon, K. M., Schultz, H. D., Zucker, I. H. & Patel, K. P., 2005, In : Methods in molecular medicine. 112, p. 59-79 21 p.

Research output: Contribution to journalReview article

14 Scopus citations

Simvastatin therapy normalizes sympathetic neural control in experimental heart failure: Roles of angiotensin II type 1 receptors and NAD(P)H oxidase

Gao, L., Wang, W., Li, Y. L., Schultz, H. D., Liu, D., Cornish, K. G. & Zucker, I. H., Sep 20 2005, In : Circulation. 112, 12, p. 1763-1770 8 p.

Research output: Contribution to journalArticle

113 Scopus citations
165 Scopus citations

The regulation of sympathetic nerve activity by angiotensin II involves reactive oxygen species and MAPK

Zucker, I. H. & Gao, L., Oct 14 2005, In : Circulation Research. 97, 8, p. 737-739 3 p.

Research output: Contribution to journalEditorial

17 Scopus citations
2006

Differential effects of cardiac sympathetic afferent stimulation on neurons in the nucleus tractus solitarius

Wang, W. Z., Gao, L., Pan, Y. X., Zucker, I. H. & Wang, W., Dec 1 2006, In : Neuroscience Letters. 409, 2, p. 146-150 5 p.

Research output: Contribution to journalArticle

34 Scopus citations
30 Scopus citations

Neuronal angiotensin II type 1 receptor upregulation in heart failure: Activation of activator protein 1 and Jun N-terminal kinase

Liu, D., Gao, L., Roy, S. K., Cornish, K. G. & Zucker, I. H., Oct 2006, In : Circulation Research. 99, 9, p. 1004-1011 8 p.

Research output: Contribution to journalArticle

63 Scopus citations

Novel mechanisms of sympathetic regulation in chronic heart failure

Zucker, I. H., Dec 2006, In : Hypertension. 48, 6, p. 1005-1011 7 p.

Research output: Contribution to journalShort survey

135 Scopus citations

Statins and Sympathetic Nerve Activity in Heart Failure

Zucker, I. H. & Gao, L., Dec 2006, In : Journal of Cardiac Failure. 12, 9, p. 759 1 p.

Research output: Contribution to journalLetter

3 Scopus citations
2007
41 Scopus citations

Cardiac sympathetic afferent stimulation augments the arterial chemoreceptor reflex in anesthetized rats

Gao, L., Pan, Y. X., Wang, W. Z., Li, Y. L., Schultz, H. D., Zucker, I. H. & Wang, W., Jan 2007, In : Journal of Applied Physiology. 102, 1, p. 37-43 7 p.

Research output: Contribution to journalArticle

31 Scopus citations

Chronic baroreceptor activation enhances survival in dogs with pacing-induced heart failure

Zucker, I. H., Hackley, J. F., Cornish, K. G., Hiser, B. A., Anderson, N. R., Kieval, R., Irwin, E. D., Serdar, D. J., Peuler, J. D. & Rossing, M. A., Nov 2007, In : Hypertension. 50, 5, p. 904-910 7 p.

Research output: Contribution to journalArticle

110 Scopus citations

Exercise training normalizes sympathetic outflow by central antioxidant mechanisms in rabbits with pacing-induced chronic heart failure

Gao, L., Wang, W., Liu, D. & Zucker, I. H., Jun 2007, In : Circulation. 115, 24, p. 3095-3102 8 p.

Research output: Contribution to journalArticle

110 Scopus citations

Exercise training prevents arterial baroreflex dysfunction in rats treated with central angiotensin II

Pan, Y. X., Gao, L., Wang, W. Z., Zheng, H., Liu, D., Patel, K. P., Zucker, I. H. & Wang, W., Mar 2007, In : Hypertension. 49, 3, p. 519-527 9 p.

Research output: Contribution to journalArticle

31 Scopus citations
1 Scopus citations
93 Scopus citations

Roles of nitric oxide and angiotensin II in the impaired baroreflex gain of pregnancy

Daubert, D. L., Liu, D., Zucker, I. H. & Brooks, V. L., Jun 2007, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 292, 6, p. R2179-R2187

Research output: Contribution to journalArticle

7 Scopus citations
2008

Angiotensin-converting enzyme 2: A new player in central sympathetic regulation?

Zucker, I. H., Mar 2008, In : Circulation Research. 102, 6, p. 628-629 2 p.

Research output: Contribution to journalEditorial

1 Scopus citations

Cardiac ErbB-1/ErbB-2 mutant expression in young adult mice leads to cardiac dysfunction

Rajagopalan, V., Zucker, I. H., Jones, J. A., Carlson, M. & Ma, Y. J., Aug 2008, In : American Journal of Physiology - Heart and Circulatory Physiology. 295, 2, p. H543-H554

Research output: Contribution to journalArticle

28 Scopus citations

Effects of angiotensin type 2 receptor overexpression in the rostral ventrolateral medulla on blood pressure and urine excretion in normal rats

Gao, L., Wang, W., Wang, W., Li, H., Sumners, C. & Zucker, I. H., Feb 2008, In : Hypertension. 51, 2 PART 2, p. 521-527 7 p.

Research output: Contribution to journalArticle

55 Scopus citations

Exercise training enhances baroreflex sensitivity by an angiotensin II-dependent mechanism in chronic heart failure

Mousa, T. M., Liu, D., Cornish, K. G. & Zucker, I. H., Mar 2008, In : Journal of Applied Physiology. 104, 3, p. 616-624 9 p.

Research output: Contribution to journalArticle

63 Scopus citations
91 Scopus citations
54 Scopus citations

Role of oxidant stress on AT1 receptor expression in neurons of rabbits with heart failure and in cultured neurons

Liu, D., Gao, L., Roy, S. K., Cornish, K. G. & Zucker, I. H., Jul 18 2008, In : Circulation Research. 103, 2, p. 186-193 8 p.

Research output: Contribution to journalArticle

48 Scopus citations
44 Scopus citations

Through the looking glass: the future of physiology. Passion, responsibility and morality in science.

Zucker, I. H., Apr 2008, In : The Physiologist. 51, 2, p. 49, 51-56

Research output: Contribution to journalArticle

1 Scopus citations
2009
30 Scopus citations

NADPH oxidase-derived reactive oxygen species in skeletal muscle modulates the exercise pressor reflex

Wang, H. J., Pan, Y. X., Wang, W. Z., Zucker, I. H. & Wang, W., Aug 2009, In : Journal of Applied Physiology. 107, 2, p. 450-459 10 p.

Research output: Contribution to journalArticle

37 Scopus citations
80 Scopus citations

Tonic glutamatergic input in the rostral ventrolateral medulla is increased in rats with chronic heart failure.

Wang, W. Z., Gao, L., Wang, H. J., Zucker, I. H. & Wang, W., Feb 2009, In : Hypertension. 53, 2, p. 370-374 5 p.

Research output: Contribution to journalArticle

44 Scopus citations
2010

Alteration in skeletal muscle afferents in rats with chronic heart failure

Wang, H. J., Li, Y. L., Gao, L., Zucker, I. H. & Wang, W., Dec 2010, In : Journal of Physiology. 588, 24, p. 5033-5047 15 p.

Research output: Contribution to journalArticle

56 Scopus citations
46 Scopus citations

Developmental changes in AT1 and AT2 receptor-protein expression in rats

Yu, L., Zheng, M., Wang, W., Rozanski, G. J., Zucker, I. H. & Gao, L., Dec 2010, In : JRAAS - Journal of the Renin-Angiotensin-Aldosterone System. 11, 4, p. 214-221 8 p.

Research output: Contribution to journalArticle

43 Scopus citations
42 Scopus citations

Exercise training normalizes ACE and ACE2 in the brain of rabbits with pacing-induced heart failure

Kar, S., Gao, L. & Zucker, I. H., Apr 2010, In : Journal of Applied Physiology. 108, 4, p. 923-932 10 p.

Research output: Contribution to journalArticle

62 Scopus citations

Exercise training prevents the exaggerated exercise pressor reflex in rats with chronic heart failure

Wang, H. J., Pan, Y. X., Wang, W. Z., Gao, L., Zimmerman, M. C., Zucker, I. H. & Wang, W., May 2010, In : Journal of Applied Physiology. 108, 5, p. 1365-1375 11 p.

Research output: Contribution to journalArticle

38 Scopus citations

The attenuation of central angiotensin II-dependent pressor response and intra-neuronal signaling by intracarotid injection of nanoformulated copper/zinc superoxide dismutase

Rosenbaugh, E. G., Roat, J. W., Gao, L., Yang, R. F., Manickam, D. S., Yin, J. X., Schultz, H. D., Bronich, T. K., Batrakova, E. V., Kabanov, A. V., Zucker, I. H. & Zimmerman, M. C., Jul 2010, In : Biomaterials. 31, 19, p. 5218-5226 9 p.

Research output: Contribution to journalArticle

58 Scopus citations
2011

AT2 receptor signaling and sympathetic regulation

Gao, L. & Zucker, I. H., Apr 2011, In : Current Opinion in Pharmacology. 11, 2, p. 124-130 7 p.

Research output: Contribution to journalReview article

50 Scopus citations
45 Scopus citations